1. GABA-receptors in peripheral tissues.
- Author
-
Ong J and Kerr DI
- Subjects
- Animals, Cardiovascular Physiological Phenomena, Cardiovascular System analysis, Endocrine Glands analysis, Endocrine Glands physiology, Gallbladder analysis, Gallbladder physiology, Lung analysis, Lung physiology, Nervous System analysis, Nervous System Physiological Phenomena, Receptors, GABA-A analysis, Urinary Bladder analysis, Urinary Bladder physiology, Urogenital System analysis, Urogenital System physiology, Receptors, GABA-A physiology
- Abstract
Gamma-aminobutyric acid (GABA) and its receptors are found in a wide range of peripheral tissues, including parts of the peripheral nervous system, endocrines, and non-neural tissues such as smooth muscle and the female reproductive system. In all these, both GABAA- and GABAB-receptor types are found, with good evidence for a physiological role in the gut, pancreatic islets and the urinary bladder. In some tissues, the pharmacology of GABA-induced actions is quite atypical and should be further explored with the newer ligands and modulators for GABAA- and GABAB-receptors.
- Published
- 1990
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