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GABA-receptors in peripheral tissues.
- Source :
-
Life sciences [Life Sci] 1990; Vol. 46 (21), pp. 1489-501. - Publication Year :
- 1990
-
Abstract
- Gamma-aminobutyric acid (GABA) and its receptors are found in a wide range of peripheral tissues, including parts of the peripheral nervous system, endocrines, and non-neural tissues such as smooth muscle and the female reproductive system. In all these, both GABAA- and GABAB-receptor types are found, with good evidence for a physiological role in the gut, pancreatic islets and the urinary bladder. In some tissues, the pharmacology of GABA-induced actions is quite atypical and should be further explored with the newer ligands and modulators for GABAA- and GABAB-receptors.
- Subjects :
- Animals
Cardiovascular Physiological Phenomena
Cardiovascular System analysis
Endocrine Glands analysis
Endocrine Glands physiology
Gallbladder analysis
Gallbladder physiology
Lung analysis
Lung physiology
Nervous System analysis
Nervous System Physiological Phenomena
Receptors, GABA-A analysis
Urinary Bladder analysis
Urinary Bladder physiology
Urogenital System analysis
Urogenital System physiology
Receptors, GABA-A physiology
Subjects
Details
- Language :
- English
- ISSN :
- 0024-3205
- Volume :
- 46
- Issue :
- 21
- Database :
- MEDLINE
- Journal :
- Life sciences
- Publication Type :
- Academic Journal
- Accession number :
- 2162457
- Full Text :
- https://doi.org/10.1016/0024-3205(90)90421-m