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Your search keyword '"Eunice W. Kagucia"' showing total 2 results
Start Over Author "Eunice W. Kagucia" Publisher cold spring harbor laboratory
2 results on '"Eunice W. Kagucia"'

1. Temporal trends of SARS-CoV-2 seroprevalence in transfusion blood donors during the first wave of the COVID-19 epidemic in Kenya

Author

Kadondi Kasera, Mercy Mwangangi, Anthony Etyang, Sammy Kihara, Shirine Voller, Ambrose Agweyu, Christian Bottomley, Perpetual Wanjiku, Irene Orgut, John N. Gitonga, J. Anthony G. Scott, Henry K. Karanja, Sophie Uyoga, Lynette Isabella Ochola-Oyier, Daniel B. Wright, Edwine Barasa, Elizabeth Odhiambo, James Nyagwange, Ifedayo M. O. Adetifa, Rashid Aman, George M. Warimwe, James Tuju, Benjamin Tsofa, Katherine E. Gallagher, Khamisi Kithi, Thomas Rotich, Eunice W. Kagucia, Wangari Ng’ang’a, Patrick Amoth, Philip Bejon, Daisy Mugo, Mark Otiende, Christine Yegon, Charles Rombo, and Teresa Lambe

Subjects
Transmission (mechanics), Coronavirus disease 2019 (COVID-19), business.industry, law, Environmental health, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), virus diseases, Medicine, Seroprevalence, Test performance, business, law.invention, Sampling bias
Abstract

Observed SARS-CoV-2 infections and deaths are low in tropical Africa raising questions about the extent of transmission. We measured SARS-CoV-2 IgG by ELISA in 9,922 blood donors across Kenya and adjusted for sampling bias and test performance. By 1st September 2020, 577 COVID-19 deaths were observed nationwide and seroprevalence was 9.1% (95%CI 7.6-10.8%). Seroprevalence in Nairobi was 22.7% (18.0-27.7%). Although most people remained susceptible, SARS-CoV-2 had spread widely in Kenya with apparently low associated mortality.

Published
2021

2. Sero-surveillance for IgG to SARS-CoV-2 at antenatal care clinics in two Kenyan referral hospitals

Author

Kadondi Kasera, Eunice W. Kagucia, Edwine Barasa, Christian Bottomley, John N. Gitonga, Adetifa Imo., Rabia Aziza, Leonard Ndwiga, Amek Nyaguara, Wangari Ng’ang’a, Scott Jag., Henry K. Karanja, James Tuju, Patrick Amoth, Lynette Isabella Ochola-Oyier, Lucy B. Ochola, Daisy Mugo, Sophie Uyoga, Edward Otieno, Charles N. Agoti, Benjamin Tsofa, Eddy Nzomo, Gideon Nyutu, Rashid Aman, Ruth Lucinde, S Agunda, Mercy Mwangangi, Anthony Etyang, George M. Warimwe, James Nyagwange, Katherine E. Gallagher, Philip Bejon, Evanson Kamuri, Mark Otiende, K Thuranira, Ambrose Agweyu, and Perpetual Wanjiku

Subjects
medicine.medical_specialty, Kenya, Referral, Obstetrics, business.industry, Transmission (medicine), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Pandemic, medicine, Seroprevalence, Igg elisa, business, Sero surveillance
Abstract

The high proportion of SARS-CoV-2 infections that remain undetected presents a challenge to tracking the progress of the pandemic and implementing control measures in Kenya. We determined the prevalence of IgG to SARS-CoV-2 in residual blood samples from mothers attending antenatal care services at 2 referral hospitals in Kenya. We used a validated IgG ELISA for SARS-Cov-2 spike protein and adjusted the results for assay sensitivity and specificity. In Kenyatta National Hospital, Nairobi, seroprevalence in August 2020 was 49.9% (95% CI 42.7-58.0). In Kilifi County Hospital seroprevalence increased from 1.3% (95% CI 0.04-4.7) in September to 11.0% (95% CI 6.2-16.7) in November 2020. There has been substantial, unobserved transmission of SARS-CoV-2 in parts of Nairobi and Kilifi Counties.

Published
2021

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