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Objectives: Men with low physical fitness and high occupational physical activity are recently shown to have an increased risk of cardiovascular disease and all-cause mortality. The association between occupational physical activity with cardiovascular disease and all-cause mortality may also depend on leisure time physical activity. Design: A prospective cohort study. Setting: The Copenhagen City Heart Study. Participants: 7819 men and women aged 25-66 years without a history of cardiovascular disease who attended an initial examination in the Copenhagen City Heart Study in 1976-1978. Outcome measures: Myocardial infarction and all-cause mortality. Occupational physical activity was defined by combining information from baseline (1976-1978) with reassessment in 1981-1983. Conventional risk factors were controlled for in Cox analyses. Results: During the follow-up from 1976 to 1978 until 2010, 2888 subjects died of all-cause mortality and 787 had a first event of myocardial infarction. Overall, occupational physical activity predicted all-cause mortality and myocardial infarction in men but not in women (test for interaction p=0.02). High occupational physical activity was associated with an increased risk of all-cause mortality among men with low (HR 1.56; 95% CI 1.11 to 2.18) and moderate (HR 1.31; 95% CI 1.05 to 1.63) leisure time physical activity but not among men with high leisure time physical activity (HR 1.00; 95% CI 0.78 to 1.26) (test for interaction p=0.04). Similar but weaker tendencies were found for myocardial infarction. Among women, occupational physical activity was not associated with subsequent all-cause mortality or myocardial infarction. Conclusions: The findings suggest that high occupational physical activity imposes harmful effects particularly among men with low levels of leisure time physical activity. [ABSTRACT FROM AUTHOR]

Presents information on a study which aims at comparing the risk of myocardial infarction associated with smoking in men and women. Methodology of the study; Statistical analysis used in the study; Result of the study.

Examines the prevalence of arterial hypertension, history of weight change and current body weight. Significance of diet reduction in the treatment of moderate hypertension; Influence of body weight changes on arterial hypertension; Analysis on the relation between blood pressure after weight changes and predicted blood pressure for attained body weight.

Examines the association between self reported alcohol intake and subsequent mortality in Copenhagen, Denmark. Influence of sex, age, body mass index, and smoking on alcohol intake and mortality; Percentage of mortality risk on alcohol abstainers; Absence of modification by sex, age, body mass index and smoking on the risk for alcohol mortality.

The article focuses on the Copenhagen City Heart Study on longevity in joggers, published in a prestigious peer-reviewed issue. It is noted that 1878 joggers and 10 158 non-joggers for up to 35 years were followed in this large prospective longitudinal observational study, which found that a remarkable 44% lower risk of mortality during follow-up for both men and women were possessed by joggers.

Objective To assess the relation between self reported intensity and frequency of stress and first time incidence of primary breast cancer. Design Prospective cohort study with 18 years of follow-up. Setting Copenhagen City heart study, Denmark. Participants The 6689 women participating in the Copenhagen City heart study were asked about their perceived level of stress at baseline in 1981-3. These women were followed until 1999 in the Danish nationwide cancer registry, with < 0.1% loss to follow-up. Main outcome measure First time incidence of primary breast cancer. Results During follow-up 251 women were diagnosed with breast cancer. After adjustment for confounders, women with high levels of stress had a hazard ratio of 0.60 (95% confidence interval 0.37 to 0.97) for breast cancer compared with women with low levels of stress. Furthermore, for each increase in stress level on a six point stress scale an 8% lower risk of primary breast cancer was found (hazard ratio 0.92, 0.85 to 0.99). This association seemed to be stable over time and was particularly pronounced in women receiving hormone therapy. Conclusion High endogenous concentrations of oestrogen are a known risk factor for breast cancer, and impairment of oestrogen synthesis induced by chronic stress may explain a lower incidence of breast cancer in women with high stress. Impairment of normal body function should not, however, be considered a healthy response, and the cumulative health consequences of stress may be disadvantageous. [ABSTRACT FROM AUTHOR]

Discusses the results of an observational study of mortality rates among male joggers aged 20-79 in Copenhagen, Denmark. Trends in jogging habits among participants during a five-year period; Use of a Cox proportional hazards regression model in the analysis of the association between jogging and risk of death; Conclusion that regular jogging is not related to increased mortality in men.

The article discusses a study which examines the association of arcus corneae and xanthelasmata on the determination of individuals' risk of ischaemic vascular disease and death. Findings reveal that xanthelasmata can predict risk of myocardial infarction, ischaemic vascular disease and death. However, it indicates that arcus corneae is not an effective risk indicator for cardiovascular diseases.