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Your search keyword '"M.H.M. Heemskerk"' showing total 2 results
Start Over Author "M.H.M. Heemskerk" Publisher biomed central
2 results on '"M.H.M. Heemskerk"'

1. P74. A Good Manufacturing Practice procedure to generate therapeutic numbers of highly pure anti-leukaemic virus-specific T-cells

Author

Jhf Falkenburg, Renate S. Hagedoorn, M.H.M. Heemskerk, E.A.G. van Liempt, Inge Jedema, Pauline Meij, M.M. van Loenen, and R. de Boer

Subjects
Pharmacology, Cancer Research, business.industry, Immunology, Congenital cytomegalovirus infection, medicine.disease, Virus, Clinical trial, Transplantation, surgical procedures, operative, Oncology, Poster Presentation, Molecular Medicine, Immunology and Allergy, Medicine, Donor derived, Good manufacturing practice, Stem cell, business
Abstract

Meeting abstracts Recently, we have started a clinical trial to treat patients with high risk acute leukaemia with a donor-derived HA-1-TCR transduced virus-specific T-cell product as early as 8 weeks and 14 weeks after allogeneic stem cell transplantation (allo-SCT). Donor derived Cytomegalovirus

Published
2014

2. S78. Proffered paper: High-affinity CD20-specific TCRs suitable for adoptive immunotherapy can be readily isolated from the allo-repertoire using reverse immunology

Author

Jhf Falkenburg, Mp Schoonakker, Pleun Hombrink, M.H.M. Heemskerk, Lorenz Jahn, Chopie Hassan, P.A. van Veelen, and Mgd Kester

Subjects
Pharmacology, CD20, Cancer Research, biology, business.industry, Repertoire, Immunology, T-cell receptor, Adoptive immunotherapy, Invited Speaker Presentation, Chimeric antigen receptor, Oncology, biology.protein, Molecular Medicine, Immunology and Allergy, Medicine, business
Abstract

Meeting abstracts Studies using T-cell receptor (TCR) or chimeric antigen receptor (CAR) transduced T-cells have shown the effectiveness of adoptive immunotherapy to treat different malignancies. The efficacy and safety of such interventions greatly depends on good target selection to prevent on

Published
2014

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