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S78. Proffered paper: High-affinity CD20-specific TCRs suitable for adoptive immunotherapy can be readily isolated from the allo-repertoire using reverse immunology

Authors :
Jhf Falkenburg
Mp Schoonakker
Pleun Hombrink
M.H.M. Heemskerk
Lorenz Jahn
Chopie Hassan
P.A. van Veelen
Mgd Kester
Source :
Journal for Immunotherapy of Cancer
Publication Year :
2014
Publisher :
BioMed Central, 2014.

Abstract

Meeting abstracts Studies using T-cell receptor (TCR) or chimeric antigen receptor (CAR) transduced T-cells have shown the effectiveness of adoptive immunotherapy to treat different malignancies. The efficacy and safety of such interventions greatly depends on good target selection to prevent on

Details

Language :
English
ISSN :
20511426
Volume :
2
Issue :
Suppl 2
Database :
OpenAIRE
Journal :
Journal for Immunotherapy of Cancer
Accession number :
edsair.doi.dedup.....ba621b2fb38a9932f1365a9d61147874