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Your search keyword '"Natural immunosuppression"' showing total 3 results
Start Over Descriptor "Natural immunosuppression" Publisher american society of hematology
3 results on '"Natural immunosuppression"'

1. Killer aAPCs as tools for immunosuppression

Author

Hermann Einsele

Subjects
Natural immunosuppression, medicine.drug_class, Chemistry, medicine.medical_treatment, Immunology, Immunosuppression, Cell Biology, Hematology, Fas receptor, Monoclonal antibody, Biochemistry, Cell biology, Therapeutic immunosuppression, medicine
Abstract

Schutz and colleagues have generated killer artificial antigen-presenting cells (κaAPCs) by coupling an apoptosis-inducing α-Fas (CD95)–IgM mAb together with HLA-A2-IgG1 molecules covalently on the surface of epoxy beads. Specific T-cell depletion was rapidly achieved in 30 minutes in a Fas/

Published
2008

2. Immune Tolerance Resulting in a Dramatic Clinical Improvement in a High-Responding Inhibitor Hemophilia A Patient Using Immunosuppression with Mycofenolate Mofetil and a Factor VIII Concentrate Containing Von Willebrand Factor

Author

Yacine Taoufik, Anne Rafowicz, Thierry Lambert, Benoît Guillet, Cécile Goujard, and Marie Dreyfus

Subjects
Natural immunosuppression, biology, business.industry, medicine.medical_treatment, Immunology, Immunosuppression, Cell Biology, Hematology, Hemarthrosis, Recombinant coagulation factor VIIa, medicine.disease, Biochemistry, Immune tolerance, Immunophenotyping, Benefit analysis, Von Willebrand factor, biology.protein, Medicine, business
Abstract

A 40 year-old Caucasian patient with severe familial hemophilia A (FVIII These preliminary results show that this IT treatment, performed despite a high theoretical risk of failure, resulted in this patient in a dramatic clinical improvement, even though biological criteria of success have not yet been achieved. The respective roles of the type of FVIII concentrate, and of immunosuppression remain to be assessed, as well as the cost/benefit analysis on a longer follow-up period.

Published
2005

3. On the TRAIL of HIV-induced immunosuppression

Author

Pierre-Olivier Vidalain

Subjects
Natural immunosuppression, Death ligands, business.industry, medicine.medical_treatment, Immunology, Human immunodeficiency virus (HIV), Immunosuppression, Cell Biology, Hematology, medicine.disease_cause, Biochemistry, Therapeutic immunosuppression, medicine, business
Abstract

Comment on Herbeuval et al, page [2458][1] Several recent reports have documented the critical contribution of TRAIL to T-cell depletion during HIV infection. In this issue of Blood , Herbeuval and colleagues provide evidence that antigen-presenting cells are a major source of this death ligand

Published
2005

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