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Immune Tolerance Resulting in a Dramatic Clinical Improvement in a High-Responding Inhibitor Hemophilia A Patient Using Immunosuppression with Mycofenolate Mofetil and a Factor VIII Concentrate Containing Von Willebrand Factor
- Source :
- Blood. 106:3220-3220
- Publication Year :
- 2005
- Publisher :
- American Society of Hematology, 2005.
-
Abstract
- A 40 year-old Caucasian patient with severe familial hemophilia A (FVIII These preliminary results show that this IT treatment, performed despite a high theoretical risk of failure, resulted in this patient in a dramatic clinical improvement, even though biological criteria of success have not yet been achieved. The respective roles of the type of FVIII concentrate, and of immunosuppression remain to be assessed, as well as the cost/benefit analysis on a longer follow-up period.
- Subjects :
- Natural immunosuppression
biology
business.industry
medicine.medical_treatment
Immunology
Immunosuppression
Cell Biology
Hematology
Hemarthrosis
Recombinant coagulation factor VIIa
medicine.disease
Biochemistry
Immune tolerance
Immunophenotyping
Benefit analysis
Von Willebrand factor
biology.protein
Medicine
business
Subjects
Details
- ISSN :
- 15280020 and 00064971
- Volume :
- 106
- Database :
- OpenAIRE
- Journal :
- Blood
- Accession number :
- edsair.doi...........a10f19efe4fb35da660f3ba4455e7396