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Start Over Author "Frank Heckel" Publisher american chemical society (acs)
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1. Production of Natural Methyl Anthranilate by Microbial N-Demethylation of N-Methyl Methyl Anthranilate by the Topsoil-Isolated Bacterium Bacillus megaterium

Author

Peter Schreier, Frank Heckel, Dag Harmsen, and Marcus Taupp

Subjects
Bacillaceae, biology, Stereochemistry, Chemistry, Methyl anthranilate, fungi, General Chemistry, biology.organism_classification, Methylation, Bacillales, chemistry.chemical_compound, Biotransformation, Biochemistry, Bacillus megaterium, bacteria, ortho-Aminobenzoates, General Agricultural and Biological Sciences, Soil Microbiology, Bacteria, Demethylation
Abstract

Bacillus megaterium, isolated in a screening process from topsoil, was used for N-demethylation of natural N-methyl methyl anthranilate to produce natural methyl anthranilate. Maximal productivity of 70 mg/L/day was achieved under laboratory-scale conditions without further optimization. No byproducts were observed. Thus, production of “natural” methyl anthranilate using B. megaterium is a significant improvement over comparable already existing procedures. Keywords: Bacillus megaterium; bioflavor; biotransformation; methyl anthranilate; N-demethylation; N-methyl methyl anthranilate

Published
2005
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