25 results on '"Worek, Franz"'
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2. Protein networking: nicotinic acetylcholine receptors and their protein–protein-associations
3. Effects of the nerve agent VX on hiPSC-derived motor neurons
4. Trauma-toxicology: concepts, causes, complications
5. Targeting miR-497-5p rescues human keratinocyte dysfunction upon skin exposure to sulfur mustard
6. Disulfide-adducts with cysteine residues in human serum albumin prove exposure to malodorous mercaptans in vitro
7. Identification of ligands binding to MB327-PAM-1, a binding pocket relevant for resensitization of nAChRs
8. Determination of tissue distribution of VX and its metabolites EMPA and EA-2192 in various rat tissues by LC-ESI-MS/MS after phosphotriesterase treatment
9. Synthesis and biological evaluation of novel MB327 analogs as resensitizers for desensitized nicotinic acetylcholine receptors after intoxication with nerve agents
10. The use of bispyridinium non-oxime analogues for the restoration of nerve agent impaired neuromuscular transmission in rat hemidiaphragms – Structure optimization
11. Inhibition kinetics of acetylcholinesterase and butyrylcholinesterase from various species by 2-(2-cresyl)-4H-1,3,2-benzodioxaphosphorin-2-oxide (CBDP)
12. Uncharged mono- and bisoximes: In search of a zwitterion to countermeasure organophosphorus intoxication
13. Suitability of human HepaRG cells and liver spheroids as in vitro model to investigate the bioactivation of the organothiophosphate pesticide parathion
14. Screening for new ligands of the MB327-PAM-1 binding site of the nicotinic acetylcholine receptor
15. Restoration of nerve agent impaired neuromuscular transmission in rat diaphragm by bispyridinium non-oximes – Structure-activity relationships
16. Toxicokinetic analysis of the highly toxic nerve agent VX in commercially available multi-organ-chips – Ways to overcome compound absorption
17. MS Binding Assays with UNC0642 as reporter ligand for the MB327 binding site of the nicotinic acetylcholine receptor
18. AChE reactivation in precision-cut lung slices following organophosphorus compound poisoning
19. Cell-Sonar, a Novel Method for Intracellular Tracking of Secretory Pathways.
20. Konstruktion und gentechnische Herstellung katalytischer Bioscavenger zur Detoxifizierung phosphororganischer Verbindungen
21. 44th International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT), 28–31 May 2024, Munich, Germany.
22. The influence of the model pesticides parathion and paraoxon on human cytochrome P450 and associated oxygenases in HepaRG cells.
23. Development of a scintillation proximity assay for [ 3 H]epibatidine binding sites of Tetronarce californica muscle-type nicotinic acetylcholine receptor.
24. Concentration-dependent effects of the nerve agents cyclosarin and VX on cytochrome P450 in a HepaRG cell-based liver model.
25. Mercaptans in malodorants break disulfide bridges in human serum albumin and form adducts suitable as biomarkers of exposure in vitro.
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