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1. Internal Marketing Tools

Author

Rezaei, Niloufar, Rahmatabadi, Yazdan, Akbari, Morteza, Foroudi, Pantea, University of Tehran, Foroudi, Pantea, editor, and Akbari, Morteza, editor

Published
2024
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3. List of contributors

Author

Agwamba, Ernest C., primary, Ahadian, Samad, additional, Ahmadi, Fatemeh Maghsood, additional, Ahmadian, Roohollah, additional, Akbari, Babak, additional, Akhtari, Negin, additional, Alarcin, Emine, additional, Alem, Halima, additional, Ancira-Cortez, Alejandra, additional, Aref, Amir Reza, additional, Avci-Adali, Meltem, additional, Ayran, Musa, additional, Azarian, Maryam, additional, Bal-Öztürk, Ayça, additional, Barabadi, Hamed, additional, Barati, Maedeh, additional, Bardouni, Mohammad Mahdi, additional, Barzegar, Sajjad, additional, Bilakaya, Besa, additional, Bozlar, Michael, additional, Bozorgchami, Negar, additional, Camlik, Gamze, additional, Cekuc, Mehmet Sertac, additional, Chakafana, Graham, additional, Chakraborty, Gulmi, additional, Chhikara, Nidhi, additional, Cruz-Nova, Pedro, additional, Davari-Kia, Kamyar, additional, De, Ranjit, additional, Degim, Ismail Tuncer, additional, Degim, Zelihagul, additional, Eivazzadeh-Keihan, Reza, additional, Ezati, Negin, additional, Farahani, Ehsan Ortegoli, additional, Farani, Marzieh Ramezani, additional, Fateh, Sahand Tehrani, additional, Fateh, Sepand Tehrani, additional, Fatehi, Dorin, additional, Ghorbani-Bidkorpeh, Fatemeh, additional, Gibbens-Bandala, Brenda, additional, Goshtasbi, Nazanin, additional, Gunduz, Oguzhan, additional, Haeri, Azadeh, additional, Hakimi, Fatemeh, additional, Hamidi, Mehrdad, additional, Hashemi, Atieh, additional, Hassan, Moustapha, additional, Hojjati, Saba, additional, Hosseinabadi, Tahereh, additional, Hosseinpour-Moghadam, Reza, additional, Huh, Yun Suk, additional, Imani, Mahsa, additional, Ipek, Tuba Canak, additional, Jabbari, Farzaneh, additional, Jahani, Reza, additional, Jounaki, Kamyar, additional, Kakavand, Melika, additional, Karami, Kimiya, additional, Karslı, Seher, additional, Katerere, David R., additional, Kaushik, Ajeet, additional, Khajeamiri, Yasaman, additional, Khan, Sofia, additional, Khoramipour, Mahsa, additional, Khoskam, Maryam, additional, Koyuncuoglu, Rumeysa, additional, Kumar, Anuj, additional, Kumar, Govindarajan V., additional, Kumar, Krishan, additional, Kumari, Sonika, additional, Lalebeigi, Farnaz, additional, Lim, Vuanghao, additional, Lotfi, Malihe, additional, Lotfi, Mohammad Javad, additional, Mahata, Manoj Kumar, additional, Makwikwi, Tendai, additional, Maleki, Ali, additional, Maleki, Aziz, additional, Maleksabet, Hanieh, additional, Manicum, Amanda-Lee E., additional, Masoumi, Niloofar, additional, Mehryab, Fatemeh, additional, Meléndez-Alafort, Laura, additional, Merati, Faezeh, additional, Mirshafiyan, Mahshad, additional, Moammeri, Ali, additional, Mohit, Elham, additional, Moradi, Ashkan, additional, Mortazavi, Seyed Alireza, additional, Mortazavi, Seyedeh Maryam, additional, Mosayebnia, Mona, additional, Mostafavi, Ebrahim, additional, Movahed, Mahsa Azami, additional, Naderi, Nooshin, additional, Naei, Vahid Yaghoubi, additional, Namazifard, Saina, additional, Nasiri, Azadeh, additional, Nasri, Negar, additional, Nazari, Hojjatollah, additional, Nejati, Omid, additional, Noqani, Hesam, additional, Ocampo-García, Blanca, additional, Ozarici, Huseyin Berkay, additional, Özcan-Bülbül, Ece, additional, Preetam, Subham, additional, Rad, Dorsa Morshedi, additional, Ramazani, Ali, additional, Rath, Rajeswari, additional, Reeves, Sheena M., additional, Rezaei, Niloufar, additional, Rostami, Sanaz, additional, Saadatidizaji, Zahra, additional, Sabzini, Mahdi, additional, Sadat, Zahra, additional, Sadighian, Somayeh, additional, Sadri, Bahareh, additional, Sahrayi, Hamidreza, additional, Saleemi, Mansab Ali, additional, Salehi-Najafabadi, Amir, additional, Samadi, Amirmasoud, additional, Sanyal, Rupa, additional, Sarrami Foroushani, Elnaz, additional, Seyedhamzeh, Mohammad, additional, Shamsabadipour, Amin, additional, Sharma, Ajay, additional, Sharma, Anil Kumar, additional, Sharma, Anirudh, additional, Sharma, Saurabh, additional, Sharma, Varruchi, additional, Singh, Jasdeep, additional, Song, Yo Han, additional, Soni, Savita, additional, Sood, Ankur, additional, Subudhi, P. Debishree, additional, Tabarzad, Maryam, additional, Tabatabaei, Mahsa Seyed, additional, Taghizadeh, Fatemeh, additional, Tayebi, Lobat, additional, Ulag, Songul, additional, Uyar, Perihan, additional, Vosough, Massoud, additional, Warkiani, Majid Ebrahimi, additional, Yavari, Maryam, additional, Yaşayan, Gökçen, additional, Yildiz, Irem, additional, Zare, Iman, additional, Zare, Mohammad Reza, additional, Zarepour, Atefeh, additional, Zarkesh, Ibrahim, additional, and Zarrabi, Ali, additional

Published
2024
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7. Chitosan‐coated nanoparticles in innovative cancer bio‐medicine.

Author

Rezaei, Niloufar, Zarkesh, Ibrahim, Fotouhi, Alireza, Alikhani, Hani Keshavarz, Hassan, Moustapha, and Vosough, Massoud

Subjects
*CHITOSAN, *NANOPARTICLES, *CYTOTOXINS, *PRODUCTION methods, *ANTIBACTERIAL agents, *BIODEGRADABLE plastics
Abstract

In the recent decade, nanoparticles (NPs) have had enormous implications in cancer biomedicine, including research, diagnosis, and therapy. However, their broad application still faces obstacles due to some practical limitations and requires further development. Recently, there has been more interest in the coated class of nanoparticles to address those challenges. Chitosan‐coated NPs are simple to produce, biodegradable, biocompatible, exhibit antibacterial activity, and have less cytotoxicity. This study provides an updated and comprehensive overview of the application of chitosan‐coated NPs as a promising class of NPs in cancer biomedicine. Additionally, we discussed chitosan‐coated lipid, metal, and polymer‐based nanoparticles in biomedical applications. Furthermore, different coating methods and production/characterization procedures were reviewed. Moreover, the biological and physicochemical advantages of chitosan‐coated NPs, including facilitated controlled release, greater physicochemical stability, improved cell/tissue interaction, and enhanced bioavailability of medications, were highlighted. Finally, the prospects of chitosan‐coated NPs in cancer biomedicine were discussed. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Nano-based drug delivery systems in hepatocellular carcinoma.

Author

Abtahi, Maryam Sadat, Fotouhi, Alireza, Rezaei, Niloufar, Akalin, Hilal, Ozkul, Yusuf, Hossein-Khannazer, Nikoo, and Vosough, Massoud

Abstract

AbstractThe high recurrence rate of hepatocellular carcinoma (HCC) and poor prognosis after medical treatment reflects the necessity to improve the current chemotherapy protocols, particularly drug delivery methods. Development of targeted and efficient drug delivery systems (DDSs), in all active, passive and stimuli-responsive forms for selective delivery of therapeutic drugs to the tumour site has been extended to improve efficacy and reduce the severe side effects. Recent advances in nanotechnology offer promising breakthroughs in the diagnosis, treatment and monitoring of cancer cells. In this review, the specific design of DDSs based on the different nano-particles and their surface engineering is discussed. In addition, the innovative clinical studies in which nano-based DDS was used in the treatment of HCC were highlighted. [ABSTRACT FROM AUTHOR]

Published
2024
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10. 3D Printing of Alginate/Chitosan-Based Scaffold Empowered by Tyrosol-Loaded Niosome for Wound Healing Applications: In Vitro and In Vivo Performances.

Author

Beram FM, Ali SN, Mesbahian G, Pashizeh F, Keshvadi M, Mashayekhi F, Khodadadi B, Bashiri Z, Moeinzadeh A, Rezaei N, Namazifard S, Hossein-Khannazer N, and Tavakkoli Yaraki M

Subjects
Mice, Animals, Liposomes, Alginates pharmacology, Alginates chemistry, Wound Healing, Anti-Bacterial Agents pharmacology, Anti-Bacterial Agents therapeutic use, Anti-Bacterial Agents chemistry, Printing, Three-Dimensional, Chitosan pharmacology, Chitosan chemistry, Phenylethyl Alcohol analogs & derivatives
Abstract

This study introduces a tyrosol-loaded niosome integrated into a chitosan-alginate scaffold (Nio-Tyro@CS-AL), employing advanced electrospinning and 3D printing techniques for wound healing applications. The niosomes, measuring 185.40 ± 6.40 nm with a polydispersity index of 0.168 ± 0.012, encapsulated tyrosol with an efficiency of 77.54 ± 1.25%. The scaffold's microsized porous structure (600-900 μm) enhances water absorption, promoting cell adhesion, migration, and proliferation. Mechanical property assessments revealed the scaffold's enhanced resilience, with niosomes increasing the compressive strength, modulus, and strain to failure, indicative of its suitability for wound healing. Controlled tyrosol release was demonstrated in vitro, essential for therapeutic efficacy. The scaffold exhibited significant antibacterial activity against Pseudomonas aeruginosa and Staphylococcus aureus , with substantial biofilm inhibition and downregulation of bacterial genes ( ndvb and icab ). A wound healing assay highlighted a notable increase in MMP-2 and MMP-9 mRNA expression and the wound closure area (69.35 ± 2.21%) in HFF cells treated with Nio-Tyro@CS-AL. In vivo studies in mice confirmed the scaffold's biocompatibility, showing no significant inflammatory response, hypertrophic scarring, or foreign body reaction. Histological evaluations revealed increased fibroblast and macrophage activity, enhanced re-epithelialization, and angiogenesis in wounds treated with Nio-Tyro@CS-AL, indicating effective tissue integration and repair. Overall, the Nio-Tyro@CS-AL scaffold presents a significant advancement in wound-healing materials, combining antibacterial properties with enhanced tissue regeneration, and holds promising potential for clinical applications in wound management.

Published
2024
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