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Part of the Drugs in series, this easily accessible pocket-sized guide covers the optimal use of medications when treating patients with neurological ailments. This second edition of Drugs in Neurology outlines the indications, contra-indications, side-effects, and important interactions of each drug. Since the publication of the first Drugs in Neurology, a revolution in the neurological sciences has been underway with numerous previously untreatable conditions, receiving disease modifying research. This edition has been updated in its entirety to mirror the significant progress made in each field of neurology, including new drug profiles on emerging/recently licensed agents and a new chapter covering Neurogenetics. Practical aspects related to prescribing and therapeutic drug monitoring are explored and based on the most up-to-date evidence-based guidance. This practical handbook is relevant to neurology and neurosurgery registrars in training, consultants, general practitioners, general physicians, junior doctors, specialist nurses, pharmacists, and medical students.

Many rare diseases are genetic and lack effective cures. Herbal medicine, developed by ancient healers without the benefit of modern cell biology knowledge, focuses on alleviating symptoms associated with uncommon conditions. Herbal Medicine for Rare Diseases: Alleviating Symptoms by GMP Herbal Formulations adopts an herbal medicine approach to addressing signs and symptoms of rare diseases.Each herb possesses a multitude of compounds that allow it to treat various conditions, while a single condition can often be addressed by several different herbs, illustrating complex relationships that artificial intelligence (AI) excels at deciphering. The herbal prescriptions in this book are generated using AI models, trained on a decade's worth of medical insurance data from Taiwan, featuring the use of Good Manufacturing Practice (GMP)-certified traditional Chinese medicine (TCM) products. The connection between deep learning and big data ensures that the trained AI model represents the collective wisdom of ~5,000 herbal medical doctors in Taiwan who contributed to the training data.Features Prescribes granulated herbal products sourced from GMP-certified manufacturers to ensure quality and safety Provides precise dosage information for the GMP herbal products in every prescription Includes a wealth of common and alternative herbal prescriptions tailored for specific conditions or combinations thereof Cites evidence from preclinical and clinical studies of the herb and formula to offer insights into their efficacy and mechanisms In each section Herbal Medicine for Rare Diseases: Alleviating Symptoms by GMP Herbal Formulations, AI-generated prescriptions are meticulously annotated with evidence from modern pharmacological and phytochemical studies of the herbs and multi-herb formulas included in the prescriptions. This book is beneficial for health professionals and practitioners, particularly those who specialise in complementary, alternative, and herbal medicine.

For decades, Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics has served as the ultimate resource for clinicians integrating genetics and genomics into medical practice. With detailed coverage in contributions from more than 250 of the world's most trusted authorities in medical genetics and a series of 11 volumes available for individual sale, the seventh edition of this classic reference includes the latest information on seminal topics such as prenatal diagnosis, genome sequencing, public health genetics, and genetic counseling. Volumes 3–11 cover diagnosis, management, and treatment of both rare and common disorders in all organ systems. Students, medical providers, and researchers all benefit from the latest information about the role of the genome in health and disease. This comprehensive yet practical resource emphasizes theory and research fundamentals across the full spectrum of applications to medicine. In this volume, leading physicians and researchers thoroughly examine medical genetics and genomics as applied to endocrine, skin, connective tissue and skeletal disorders, with emphasis on understanding the genetic mechanisms underlying these conditions, diagnostic approaches, and treatment methods that make use of current genomic technologies and translational studies. With regular advances in genomic technologies propelling precision medicine into the clinic, Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics, seventh edition, bridges the gap between high-level molecular genetics and genomics and practical application and serves as an invaluable clinical tool for the health professionals and researchers. - Thoroughly introduces genetic researchers, students, and healthcare professionals to the genetic and genomic bases of endocrinologic, dermatologic, connective tissue, and skeletal disorders - Includes color images supporting identification, concept illustration, and method processing - Features contributions by leading international researchers and specialist medical practitioners

This book contains the essential information required by physicians and bench scientists to understand the definition of a given autoimmune disease and its diagnostic criteria and treatment. Autoimmune diseases are a family of more than one hundred chronic, and often disabling, illnesses that develop when underlying defects in the immune system lead the body to attack its own organs, tissues, and cells. In Autoimmune Disease Diagnosis: Systemic and Organ-specific Diseases, the editors have gathered a critical review by renowned experts of more than 120 autoimmune diseases. A contemporary overview of these conditions with special emphasis on diagnosis is presented. This edition of Autoimmune Disease Diagnosis is divided into two parts, the first covering systemic autoimmune diseases, and the second covering organ-specific autoimmune diseases. They cover all the newly approved classification criteria, such as those for systemic lupus erythematosus, antiphospholipid syndrome, several systemic vasculitis, etc. This edition also reviews newly described systemic autoimmune conditions: immune-mediated necrotizing myopathy, VEXAS, immunoglobulin G4-associated autoimmune disease, autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA), and autoimmune manifestations induced by immune-therapies. Several organ-specific diseases have been added, including autoimmune alopecia and other immune-mediated dermatosis, autoimmune encephalitis, and autoimmune dysautonomia, among others. This is an essential guide to the diagnosis of autoimmune diseases for internists, rheumatologists, clinical immunologists, primary care physicians, and bench scientists.

Greenfield's is the world's leading neuropathology reference. It provides a comprehensive account of the pathological findings in neurological disease, their biological basis, and their clinical manifestations. The two volume work provides a remarkable text which is clear, comprehensive and precise with exceptional illustrations. The tenth edition features fully updated sections covering CNS tumours, neurodegeneration, skeletal muscle, epilepsy, paediatric and forensic neuropathology.Expert coverage from an international team of Editors and contributors ensures authoritative and up to date content. The two volume set includes a downloadable and easily used e-version. This is a tried and tested reference for scientists, clinicians, researchers, and students who wish to learn more about neurological disease.

By weaving vignettes and case studies throughout, this fascinating and original textbook provides an accessible primer not only on the key principles of neuroscience but, crucially, how they may manifest in the everyday lives of people with neurological conditions.Each chapter begins with the story of a person or family, including a description of what they want to do in their everyday life, before presenting the neuroscientific principles that underlie this person's situation. Rather than a technical book about neuroanatomy, physiology, or pathology, the spotlight is on understanding the way that neurological differences impact a person's life. Through focusing on a particular condition, each chapter highlights a different aspect of the nervous system, and what happens when things change. A wide range of topics are covered, from conditions such as Parkinson's, dementia, MS, and autism, to conditions resulting from traumatic events such as spinal cord injuries, stroke, and chronic pain. The goal of the book is to trace a thread from neuroscience to how the nervous system affects active participation in daily activities. This approach gives students and professionals a thorough and informed grounding to support problem-solving in practice, improving evidence-based assessment, interventions, and outcomes.Following current evidence-based teaching practices, this text emphasizes engaged teaching/learning methods throughout each chapter to encourage students'own active discovery. This ground-breaking text will be essential reading for any health science students as well as professionals in practice.

Motor Speech Disorders: Diagnosis and Treatment, Fourth Edition offers a detailed yet streamlined introduction to motor speech disorders for graduate speech-language pathology students and beginning clinicians. The text begins with a brief historical overview of motor speech disorders, providing useful context for understanding the technology and methodology used by today's speech-language pathologists for assessment and treatment. The book also provides a practical introduction to the human motor system with 45 full-color anatomical illustrations enabling readers to more easily understand the challenging material. A full chapter is dedicated to the assessment of the disorders and includes a detailed explanation of the complete motor speech examination.

Acquired Neurogenic Communication Disorders: An Integrated Clinical Approach provides an overview of acquired neurogenic communication and swallowing disorders for undergraduate courses in communication sciences and disorders programs. Compared to other books on this subject, this text is organized by anatomical systems and locations, not by disorder. The authors aim to teach students about the cognitive, speech, language, and swallowing disorders that occur with damage to neurological systems in a manner that breaks down silos that artificially separate disorders that routinely co-occur. This approach reflects the reality that most individuals with acquired brain injuries have multiple cognitive, communication, and swallowing disorders.

Third Edition AJN Book-of-the-Year Award Winner: Child Health! This acclaimed text delivers the specialized knowledge and skills required for in-depth physical and psychosocial assessment and treatment of children from birth through adolescence. Comprehensive and detailed, it emphasizes the unique anatomic and physiologic differences between infants, children, and adults and underscores the need for a distinct approach to the pediatric population. The fourth edition is updated with a unique chapter on diagnostic reasoning along with new content on this topic throughout. Also included is a new section on the pediatric telehealth visit and discussion of the clinical impact of the pandemic on the physical and psychological assessment of pediatric patients. New case studies and critical thinking exercises for each chapter illuminate content along with abundant four-color photograph and images. The text is written with a level of depth that makes it ideal both as a text for advanced practice nursing students and as a reference for practicing pediatric healthcare providers. It encompasses the physical, psychosocial, developmental, and cultural aspects of child assessment. Detailed tables list normal growth and developmental milestones as well as developmental red flags and developmental screening tools. New to the Fourth Edition: A fully revised chapter on mental health assessment of children A new section on providing Trauma Informed Care to children A revised chapter on diagnostic reasoning and clinical decision making along with new diagnostic reasoning content throughout Content on the pediatric telehealth visit Focus on the clinical impact of the pandemic on the physical and psychosocial assessment of pediatric patients Key Features: Organized by body system to aid in speedy information retrieval Examines the unique anatomic and physiologic differences among infants, children, and adults Addresses family, developmental, nutritional, and child mistreatment assessment Describes in detail helpful communication techniques when working with children of different developmental levels Incorporates current screening and health promotion guidelines Offers a specific chapter on the diagnostic process and formulating pediatric differential diagnoses

Using a practical, easy-to-reference signs and symptoms approach, Fenichel's Clinical Pediatric Neurology, 9th Edition, provides a solid foundation in the diagnosis and management of primary neurologic disorders of childhood while bringing you fully up to date with developments in the field. It offers step-by-step, authoritative guidance that considers each presenting symptom in terms of differential diagnosis and treatment, reflecting real-life patient evaluation and management. Perfect for board exam preparation, office use, or residency reference, this well-organized, revised edition is an ideal introduction to this complex and fast-changing field. - Defines age at onset, course of illness, clinical features, and treatment options for each neurological disease, all logically organized by neurological signs and symptoms in a highly templated format. - Brings you up to date with every aspect of the field, with integrated content on new medications, new topics such as neurological complications of COVID in children, and a new chapter on behavioral neurology. - Includes comprehensive coverage of genetics in relation to epilepsy, autism, and many neurometabolic disorders, with up-to-date coverage of genetic testing, diagnosis, and pharmacogenomics. - Features weighted differential diagnosis tables and treatment algorithms that help you quickly identify the more common and most treatable neurological disorders, as well as evaluate and manage the most difficult neurodegenerative disorders, including those caused by inborn errors of metabolism. - Provides helpful boxes that synthesize symptoms and foundational points, an increased number of imaging examples throughout, and more than 300 illustrations, tables, and charts that support and clarify the text. - Shares the knowledge and experience of clinical neurologist and epileptologist, Dr. Kaitlin C. James, and Dr. J. Eric Piña-Garza, a longtime associate and protégé of Dr. Gerald Fenichel.

The second edition of this text has proved to be a very successful pediatric study guide, helping many pediatricians around the world to study pediatrics in a very easy, simplified way. Even the most complex subjects are condensed into very straight forward and easy to remember information blocks. This book not only prepares students to pass their exams but also prepares pediatricians for general pediatric encounters, emphasizing all new updates from the American Academy of Pediatrics and American Board of Pediatrics. It has proved very popular among new pediatricians and new pediatric residents worldwide. In the last 3 years, the AAP and ABP have released a lot of updates, such as, management of fever in well-appearing infants, COVID-19, asthma management, and new vaccine guidelines from the CDC. The pediatric board exam always includes new diseases, which are included in each chapter, as well as new questions and answers that must be added to the last-minute review chapter, as well as other questions to be edited to follow the new recommendations and guidelines in pediatrics. New pictures and better quality illustrations are also included. Pediatric residents and fellows preparing for the board examination, pediatricians, and pediatric subspecialists preparing for certification maintenance will find Pediatric Board Study Guide: A Last-Minute Review, 3rd edition, easy to use and comprehensive, making it the ideal resource and study tool.

Now in its fourth edition, Occupational Hearing Loss delivers a complete overview of the hazards of occupational noise exposure, causes of hearing loss, testing of hearing, criteria to distinguish occupational hearing loss, and more. The book emphasizes medical and societal factors in its coverage of topics such as audiometry and who should do it, evoked response testing, and conductive and sensorineural hearing loss, as well as mixed, central, and functional hearing loss.Brought together by experienced practitioners and written by experts with depth and experience in the field, this book is written clearly in language accessible to non-medical personnel. No other book available has the breadth, practical detail, or comprehensive scope. A unique compendium of information about specific problems of occupational hearing loss and hearing conservation, the book is both a balanced reference and an easy-to-use guide to protecting the hearing of industrial workers.This title is an ideal read for any student or professional occupational physician, audiologist, health and safety engineer, industrial hygienist, and otolaryngologist.

Handbook of Nutritional Disorders is a comprehensive handbook covering topics in nutrition, malnutrition, and the clinical disorders associated with nutrition from deficiency to toxicity. It includes information on disorders related to carbohydrate, lipid, and protein metabolism as well as vitamin and mineral abnormalities. The book details various types of supplements, feeding methods, and therapies for many specific patients. It aims to educate readers on ways to prevent disorders resulting from all types of malnutrition and their potentially severe complications.Features Strong focus on diabetes featuring information on various forms of the disease and treatment information Detailed discussion of lipids and related disorders – cardiovascular disease is the number one cause of death, informs users on prevention and treatment of hypertension, myocardial infarction, and stroke Contains information on selective nutritional disorders including obesity, dehydration, imbalances, malabsorption, alcoholism, neuropsychiatric disorders, eating disorders, cancer, and pollutant poisonings Written for researchers, academia, and students in healthcare and nutrition fields, this book educates individuals on prevention of disorders resulting from all types of malnutrition and their potentially severe complications.

Various topics covered in this book are: Mendelian Genetics, Non-Mendelian Genetics, Genetics counseling, Cancer Genetics, Problem Solving in Genetics, Legal and Ethical Issues in Human Genetics. Provides the basic knowledge about human genetics and application of genetic principles in the practice of medicine. Important concepts of genetics with experimental details have been also incorporated. Provides diagrams, microphotographs, tables and laboratory features for easy understanding and better retention. At the end of the book an extensive glossary and question answers have been provided which will help the students to prepare them for their exams. This book will be greater use to understand the science of inheritance and its implications in the field of molecular biology and human genetics.

Handbook of Neural Engineering: A Modern Approach provides a comprehensive overview of the field from biology to recent technological advances through an interdisciplinary lens. The book is divided into three sections: 1) Biological Considerations for Neural Engineering, 2) Neural Engineering Strategies, and 3) Emerging Technologies for Neural Engineering. It provides the first comprehensive text that addresses this combination of subjects. Neurodegenerative diseases, including Alzheimer's, Parkinson's and Multiple Sclerosis, represent an enormous healthcare burden, and many of these diseases lack true cures, making it imperative to study the biological systems that become disordered to understand potential treatment options. This book covers the basic neurobiology and physiology, common neural engineering strategies, and emerging technologies in this field. It is designed to support an upper year/graduate elective course in neural engineering, and will provide a foundational overview of the field for interdisciplinary researchers, clinicians, engineers, and industry professionals. The handbook provides readers with a strong base in both biological and engineering principles along with the concepts necessary to implement solutions using Neural Engineering. - Includes coverage of foundational concepts of the fast-moving field of Neural Engineering, from overview and structure of the nervous system, cellular biology of the nervous system, extracellular matrix of the nervous system, role of the immune system in the nervous system, disease states of the nervous system, and the effects of trauma and chronic pain on the nervous system - Provides readers with understanding of Neural Engineering strategies, in key areas such as imagining, examining nervous system function, neural interfaces, Brain-Computer Interfaces, neural prostheses, neurorobotics, and neural tissue engineering - Includes a complete section on emerging technologies for neural engineering applications, such as optogenetics, gene editing, brain organoids, and modeling with organ-on-a-chip systems

An expert, concise guide on the pathophysiology and treatment of foot and ankle disordersFoot and ankle problems can be quite complex and constitute a large percentage of orthopaedic conditions, including congenital and acquired deformities, arthritis, tumors, heel pain, nerve damage, trauma, and more. Synopsis of Foot and Ankle Surgery, edited by renowned foot and ankle surgeons and educators Simon Lee and Christopher E. Gross, is an easy-to-read resource covering a wide range of foot and ankle fundamentals. The book fills a gap in the literature, and in particular orthopaedic resources, by providing a reader-friendly handbook for medical students and junior residents who need quick and reliable clinical information at their fingertips.This textbook serves as a primer for beginners as well as a resource for more established clinicians to expand current understanding and knowledge of foot and ankle pathologies and techniques. The opening five chapters lay an essential groundwork, covering anatomy, an overview of surgical approaches, biomechanics, imaging basics, and medical history and physical examination. Common and less prevalent conditions are addressed in the 18 subsequent chapters, while the final two chapters discuss orthotics and prosthetics and orthobiologics, respectively.Key FeaturesContributions from world-renowned experts in their respective fieldsA succinct resource detailing the clinical intricacies and challenges inherent to foot and ankle surgeryPearls and concepts to enhance learning, knowledge, clinical rotations, and careersHigh-quality illustrations and surgical photographs enrich understanding of underlying anatomy and techniquesThis indispensable resource will help medical students, orthopaedic and podiatric residents, nurses, and physician assistants to expand knowledge on foot and ankle anatomy and improve management of a comprehensive range of conditions.