15 results on '"Fillipo, Rebecca"'
Search Results
2. Facets of physical function assessed by patient-reported outcome measures in oncology research
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Coles, Theresa, Fillipo, Rebecca, Plyler, Kate, Hernandez, Alexy, Henke, Debra M., Arizmendi, Cara, Cantrell, Sarah, Lagoo-Deenadayalan, Sandhya, Rory Goodwin, C., LeBlanc, Thomas W., Horodniceanu, Erica G., Bhatnagar, Vishal, Reeve, Bryce B., and Weinfurt, Kevin
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- 2024
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3. What facets of physical function are most important to adults diagnosed with cancer?
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Coles, Theresa, Plyler, Kate, Hernandez, Alexy, Fillipo, Rebecca, Henke, Debra M., Arizmendi, Cara, Lagoo-Deenadayalan, Sandhya, Goodwin, C. Rory, LeBlanc, Thomas W., Horodniceanu, Erica G., Bhatnagar, Vishal, Reeve, Bryce B., and Weinfurt, Kevin P.
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- 2024
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4. Exploring Definitions of Acute Low Back Pain Severity as Predictors of Transition to Chronic Low Back Pain: A Community-Based Longitudinal Pilot Study
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Fillipo, Rebecca, primary, Burke, Colleen, additional, Kosinski, Andrzej, additional, George, Steven Z., additional, Kapos, Flavia, additional, and Goode, Adam, additional
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- 2024
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5. Transition from Acute to Chronic Low Back Pain: A Community-Based Longitudinal Study
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Burke, Colleen, primary, Fillipo, Rebecca, additional, George, Steven Z., additional, Kapos, Flavia P., additional, Kosinski, Andrzej, additional, and Goode, Adam, additional
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- 2024
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6. Characterizing Acute Low Back Pain in a Community-Based Cohort: Results from a Feasibility Cohort Study
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Burke,Colleen, Taylor,Kenneth, Fillipo,Rebecca, George,Steven, Kapos,Flavia, Danyluk,Stephanie, Kingsbury,Carla, Seebeck,Kelley, Lewis,Christopher, Ford,Emily, Plez,Cecilia, Kosinski,Andrzej, Brown,Michael, Goode,Adam, Burke,Colleen, Taylor,Kenneth, Fillipo,Rebecca, George,Steven, Kapos,Flavia, Danyluk,Stephanie, Kingsbury,Carla, Seebeck,Kelley, Lewis,Christopher, Ford,Emily, Plez,Cecilia, Kosinski,Andrzej, Brown,Michael, and Goode,Adam
- Abstract
Colleen A Burke,1,2,* Kenneth A Taylor,1,3,* Rebecca Fillipo,2 Steven Z George,1â 3 Flavia P Kapos,1,3 Stephanie T Danyluk,1 Carla A Kingsbury,4 Kelley Seebeck,1 Christopher E Lewis,4 Emily Ford,4 Cecilia Plez,4 Andrzej S Kosinski,5 Michael C Brown,6,7 Adam P Goode1â 3 1Department of Orthopedic Surgery, Duke University School of Medicine, Durham, NC, USA; 2Department of Population Health Sciences, Duke University School of Medicine, Durham, NC, USA; 3Duke Clinical Research Institute, Duke University, Durham, NC, USA; 4Duke Clinical and Translational Science Institute, Duke University School of Medicine, Durham, NC, USA; 5Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, USA; 6Department of Neurosurgery, Duke University School of Medicine, Durham, NC, USA; 7Duke Cancer Institute, Duke University, Durham, NC, USA*These authors contributed equally to this workCorrespondence: Adam P Goode, Department of Orthopedic Surgery, Duke University School of Medicine, 311 Trent Drive, Durham, NC, 27710, USA, Tel +1 919 681 6157, Fax +1 919 684 1846, Email adam.goode@duke.eduIntroduction: Acute low back pain (LBP) is a common experience; however, the associated pain severity, pain frequency, and characteristics of individuals with acute LBP in community settings have yet to be well understood. In this manuscript, two acute-LBP severity categorization definitions were developed: 1) pain impact frequency (impact-based) and 2) pain intensity (intensity-based) severity categories. The purpose of this manuscript is to describe and then compare these acute-LBP severity groups in the following characteristics: 1) sociodemographic, 2) general and physical health, and 3) psychological using a feasibility cohort study.Methods: This cross-sectional study used baseline data from 131 community-based participants with acute LBP (< 4 weeks duration before screening and ⥠30 pain-free days before acute LBP onset). Des
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- 2024
7. Characterizing Acute Low Back Pain in a Community-Based Cohort: Results from a Feasibility Cohort Study.
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Burke, Colleen A, Taylor, Kenneth A, Fillipo, Rebecca, George, Steven Z, Kapos, Flavia P, Danyluk, Stephanie T, Kingsbury, Carla A, Seebeck, Kelley, Lewis, Christopher E, Ford, Emily, Plez, Cecilia, Kosinski, Andrzej S, Brown, Michael C, and Goode, Adam P
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LUMBAR pain ,SOCIAL role ,COHORT analysis ,WORLD health ,CROSS-sectional method - Abstract
Introduction: Acute low back pain (LBP) is a common experience; however, the associated pain severity, pain frequency, and characteristics of individuals with acute LBP in community settings have yet to be well understood. In this manuscript, two acute-LBP severity categorization definitions were developed: 1) pain impact frequency (impact-based) and 2) pain intensity (intensity-based) severity categories. The purpose of this manuscript is to describe and then compare these acute-LBP severity groups in the following characteristics: 1) sociodemographic, 2) general and physical health, and 3) psychological using a feasibility cohort study. Methods: This cross-sectional study used baseline data from 131 community-based participants with acute LBP (< 4 weeks duration before screening and ≥ 30 pain-free days before acute LBP onset). Descriptive associations were calculated as prevalence ratios of categorical variables and Hedges' g for continuous variables. Results: Our analyses identified several large associations for impact-based and intensity-based categories with global mental health, global physical health, STarT Back Screening Tool risk category, and general health. Larger associations were found with social constructs (racially and ethnically minoritized, performance of social roles, and isolation) when using the intensity-based versus impact-based categorization. Discussion: This study adds to the literature by providing standard ways to characterize community-based individuals experiencing acute-LBP. The robust differences observed between these categorization approaches suggest that how we define acute-LBP severity is consequential; these different approaches may be used to improve the early identification of factors potentially contributing to the development of chronic-LBP. [ABSTRACT FROM AUTHOR]
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- 2024
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8. Use of Implementation Strategies to Promote the Uptake of Knee Osteoarthritis Practice Guidelines and Improve Patient Outcomes: A Systematic Review.
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Ramirez, Michelle M., Fillipo, Rebecca, Allen, Kelli D., Nelson, Amanda E., Skalla, Lesley A., Drake, Connor D., and Horn, Maggie E.
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KNEE osteoarthritis ,CINAHL database ,LEARNING strategies ,CONSUMERS ,QUALITY of life - Abstract
Objective: Translation of knee osteoarthritis (KOA) clinical practice guidelines (CPGs) to practice remains suboptimal. The primary purpose of this systematic review was to describe the use of implementation strategies to promote KOA CPG–recommended care. Methods: Medline (via PubMed), Embase, CINAHL, and Web of Science were searched from inception to February 23, 2023, and the search was subsequently updated and expanded on January 16, 2024. Implementation strategies were mapped per the Expert Recommendations for Implementing Change taxonomy. Risk of bias (RoB) was assessed using the Cochrane Effective Practice and Organisation of Care criteria. The review was registered prospectively (PROSPERO identifier: CRD42023402383). Results: Nineteen studies were included in the final review. All (100% [n = 4]) studies that included the domains of "provide interactive assistance," "train and educate stakeholders" (89% [n = 16]), "engage consumers" (87% [n = 13]), and "support clinicians" (79% [n = 11]) showed a change to provider adherence. Studies that showed a change to disability included the domains of "train and educate stakeholders," "engage consumers," and "adapt and tailor to context." Studies that used the domains "train and educate stakeholders," "engage consumers," and "support clinicians" showed a change in pain and quality of life. Most studies had a low to moderate RoB. Conclusion: Implementation strategies have the potential to impact clinician uptake of CPGs and patient‐reported outcomes. The implementation context, using an active learning strategy with a patient partner, restructuring funding models, and integrating taxonomies to tailor multifaceted strategies should be prioritized. Further experimental research is recommended to determine which implementation strategies are most effective. [ABSTRACT FROM AUTHOR]
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- 2024
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9. Transition from Acute to Chronic Low Back Pain in a Community-Based Cohort
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Burke, Colleen, primary, Fillipo, Rebecca, additional, George, Steven, additional, and Goode, Adam Payne, additional
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- 2024
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10. Associations Between Comorbid Pain Sites and Pain Bothersomeness with Pain Impact in Adults with Symptomatic Lumbar Spinal Stenosis: Baseline Data Analysis of the Lumbar Stenosis Prognostic Subgroups for Personalizing Care and Treatment Study
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Parman, Natasha L., Meier, Eric N., Friedly, Janna L., Suri, Pradeep, Horn, Maggie E., Burke, Colleen A., Saito, Ayumi, Heagerty, Patrick J., Jarvik, Jeffrey G., Goode, Adam P., Cizik, Amy M., Smersh, Monica, Johnston, Sandra K., Fillipo, Rebecca, and Rundell, Sean D.
- Abstract
Few studies examine how comorbid pain locations and bothersomeness impact adults with lumbar spinal stenosis (LSS). We describe the associations of the number of comorbid pain sites and cumulative bothersomeness of those sites with pain impact. This cross-sectional study uses baseline data from a cohort of adults aged ≥50 seeking non-surgical care for LSS at two spine clinics. Comorbid pain locations are summed from a self-reported checklist of 9 locations (range 0-9), and bothersomeness at each site is rated between 0-2 (range 0-18, higher indicates greater bothersomeness). Our dependent variable was a pain impact score (range 8-50), which is the sum of 8 items on the interference and function scales of the PROMIS-29 and back pain intensity rating. We use descriptive statistics and linear regression adjusted for confounders for analysis. As of September 2023, 449 participants completed the baseline data collection; 407 complete cases were analyzed. 62% were female, 37% had pain for >5 years, and 21% used opioids in the last month. The mean number of comorbid pain locations was 4.3 (SD 2.2), the mean bothersomeness was 5.9 (SD 3.2), and the mean impact was 27.7 (SD 9.0). For every additional pain site, the pain impact score increases 0.93 points (95% CI= 0.49-1.36) and pain bothersomeness increases 0.90 points (95% CI= 0.60-1.19). Comorbid pain locations and bothersomeness may be important to consider when creating a care plan to reduce pain impact in adults with LSS. Funded by the National Institutes of Health (T90 AT008544, R01 AG069891, P30AR072572).
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- 2024
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11. Longitudinal Analyses of Patient-Reported Outcomes Measurement Information System Pain Scores in the Project Baseline Health Study
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Liao, Shirley, Fillipo, Rebecca, Subramaniam, Hamsa, Nelson, Benjamin, Carroll, Megan K., Sullivan, Shannon, Mahaffey, Kenneth W, Nunes, Julio C., and Taylor, Kenneth A.
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Data describing longitudinal pain outcomes is limited, particularly among patients experiencing chronic medical and psychiatric conditions. This study analyzed longitudinal patient-reported pain intensity and interference within six disease-specific subgroups (arthritis, major depressive disorder, generalized anxiety disorder, comorbid depression and anxiety, migraine, and type 2 diabetes) as well as a healthy (free from chronic illness) comparator group from the Project Baseline Health Study, a community-based observational cohort study with data collected from 2017-2023. Cross-sectional distributions were created for pain intensity and interference scores taken at enrollment. Longitudinal correlations were calculated between pain scores and psychosocial measures collected concurrently every six months. In the analysis population (N = 2009 of 2505 total PBHS participants), each of the six disease-specific subgroups displayed higher average pain intensity and interference scores than the healthy comparator group. While 25% of healthy participants reported no pain intensity at enrollment and 37% reported no pain interference, these proportions were lower for all disease cohorts (Arthritis: 9%, 15%; Depression: 16%, 24%; Anxiety: 15%; 21%; Depression-Anxiety: 10%, 16%; Migraine: 12%; 22%; T2D: 15%, 23% - respectively). Within all subgroups, Satisfaction With Life (SWL) was the most negatively correlated with pain scores while the Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7) were the most positively correlated. By examining pain distributions and correlations in a community-based population, this study offers novel insights into how patients with chronic illnesses experience pain.
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- 2024
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12. Transition from Acute to Chronic Low Back Pain in a Community-Based Cohort
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Burke, Colleen A., Fillipo, Rebecca, George, Steven Z., Kapos, Flavia P., Kosinski, Andrzej S., Ford, Emily, Danyluk, Stephanie T., Kingsbury, Carla A., Seebeck, Kelley, Lewis, Christopher E., Plez, Cecilia, Brown, Michael C., and Goode, Adam P.
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The transition from acute to chronic low back pain (LBP) in community settings is not well understood. The purpose of this study was to assess the feasibility of recruitment and estimate the transition and continuation of chronic LBP. We also explored characteristics associated with this transition to chronic LBP. We enrolled n=131 participants, of which n=118 (90%) completed 3-month outcomes and n=111 (85%) completed 6-month outcomes. Acute LBP was defined by a duration of <4 weeks and a 30-day LBP-free period before the current acute episode. Chronic LBP was defined as pain most or every day over the past 3 months. The transition from acute to chronic LBP at 3 months was 32.2% (38/118), and at 6 months, 80.6% (25/31) of participants who transitioned at 3 months continued to have chronic LBP at 6 months. Participants with more frequent acute LBP and at an intensity of 30/100 were more likely to transition to chronic LBP (Risk Ratio (RR)=3.13, 95% Confidence Interval (CI) 1.84, 5.30) and continue to have chronic LBP at 6-months (RR=3.10, 95% CI 1.48, 6.08). Higher risk on the STarT Back Screening Tool was associated with the transition to chronic LBP at 3 months (RR=1.73, 95% CI 1.28, 2.35) and continuation of chronic LBP at 6 months (RR=1.26, 95% CI 1.10, 1.45). The recruitment of acute LBP was feasible in a community setting. Acute LBP is a common condition in the community and frequently transitions to chronic LBP, suggesting the potential for substantial burden in the community.
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- 2024
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13. Ventral Hernia Reconstruction with GORE ENFORM Biomaterial.
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Hollins AW, Atia A, Zhang G, Mateas C, Schmidt M, Fillipo R, Hope WW, and Levinson H
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Introduction: Ventral hernia repair (VHR) is one of the most common surgeries performed in the United States. Degradable mesh is the recommended choice for patients presenting with high-risk co-morbidities or increased risk for infection. GORE® ENFORM Biomaterial
TM is a biosynthetic degradable mesh that has recently been approved for use in ventral hernia reconstruction with no reports of its clinical outcomes. Methods: This study was a single surgeon case series. Patients were included in the study if they underwent VHR with GORE® ENFORM BiomaterialTM . The decision to use GORE® ENFORM BiomaterialTM was the senior surgeon's decision based on the patient's center for disease control classification. Patient comorbidities, hernia characteristics, postoperative hernia recurrence, and surgical site occurrences (SSOs) were collected at in-patient follow-up appointments and chart review. Patients were asked to complete preoperative and postoperative patient-reported outcomes (PROs) using the Patient-Reported Outcomes Measurement Information System (PROMIS) Pain Intensity short form 3a and the hernia-specific quality of life (HerQLes) survey. Results: A total of 15 patients were included in this study. The average length of follow-up was 315 days. Postoperatively, 26.7% of patients had an SSO with 4 surgical site infections. Two patients required an operative washout with mesh removal. One patient experienced hernia recurrence. Eight of the 15 patients completed preoperative and postoperative PROs. Conclusion: This is the first clinical study to report the outcomes of ventral hernia repair using ENFORM mesh. These results show that Enform mesh is an option to consider in complex ventral hernia reconstruction., Competing Interests: The authors declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: Dr Howard Levinson is a consultant for GORE. Dr William Hope is a consultant for GORE. No research or funding was provided by GORE for this study. This was a principal investigator-driven research study., (© 2022 The Author(s).)- Published
- 2024
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14. Characterizing Acute Low Back Pain in a Community-Based Cohort.
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Burke C, Taylor KA, Fillipo R, George SZ, Kapos FP, Danyluk S, Kingsbury CA, Seebeck K, Lewis CE, Ford E, Plez C, Kosinski AS, Brown MC, and Goode AP
- Abstract
Acute low back pain (LBP) is a common experience, however, the associated pain severity, pain frequency, and characteristics of individuals with acute LBP in community settings have yet to be well understood. In this manuscript, three acute LBP severity categorization definitions were used based on LBP frequency combined with either 1) pain impact frequency (impact-based) or 2) pain intensity (intensity-based), as well as LBP pain interference frequency (interference only-based) severity categories. The purpose of this manuscript is to describe and then compare these acute LBP severity groups in the following characteristics: 1) sociodemographic, 2) general and physical health, and 3) psychological. This cross-sectional study used baseline data from 131 community-based participants with acute LBP (<4 weeks duration before screening and ≥30 pain-free days before acute LBP onset). Descriptive associations were calculated as prevalence ratios for categorical variables and Hedges' g for continuous variables. Our analyses identified several large associations for impact-based and intensity-based categories with global mental health, global physical health, STarT Back Screening Tool risk category, and general health. Larger associations were found with social constructs (racially and ethnically minoritized, performance of social roles, and isolation) when using the intensity-based versus impact-based categorization. The interference-based category did not capture as much variability between acute LBP severity categories. This study adds to the literature by providing standard ways to characterize community-based individuals experiencing acute LBP. The robust differences observed between these categorization approaches suggest that how we define acute LBP severity is consequential; these different approaches may be used to improve the early identification of factors potentially contributing to the development of chronic LBP.
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- 2024
- Full Text
- View/download PDF
15. Transition from Acute to Chronic Low Back Pain in a Community-Based Cohort.
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Burke C, Fillipo R, George SZ, and Goode AP
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The transition from acute to chronic low back pain (LBP) in community settings has yet to be well understood. We recruited n=131 participants with acute LBP from the community and followed them for 3 and 6-month outcomes. Acute LBP was defined by a duration of < 4 weeks, and participants must have reported a 30-day LBP-free period before the current acute episode. Chronic LBP was defined as pain most or every day over the past 3 months. Baseline psychological, social, and demographic factors were examined as predictors of transition to chronic LBP at 3 months or continuation of chronic LBP at 6 months. The transition from acute to chronic LBP at 3 months was 32.2% ( 38/118). At 6 months, 80.7% (25/111) of participants who transitioned at 3 months continued to have chronic LBP. At 6 months, participants who identified as Black or African American were more likely than white participants to transition to chronic LBP (RR=1.76, 95% CI 1.05, 2.95) and more likely to continue to have chronic LBP (RR=2.19, 95% CI 1.14, 4.21). Those classified at baseline by both LBP most or every day and intensity of at least 30/100 were more likely to transition to chronic LBP (RR=3.13, 95% CI 1.84, 5.30) and continue to have chronic LBP at 6 months (RR=2.58, 95% CI 1.43, 4.16). The STarT Back Screening Tool and the OSPRO-YF were associated with the transition to chronic LBP at 3 months and continuation at 6 months. Participants with higher PROMIS General Health and PROMIS Physical Health scores were less likely to transition to chronic LBP or continue to have chronic LBP at 6 months. These findings identify factors of acute LBP in the community that may predict the transition to chronic LBP. Larger studies are needed to confirm these findings and better understand the mechanisms driving the transition to chronic LBP.
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- 2024
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