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1. Antibodies to Glutamate Reduce the IL-6 Content in Cerebral Structures in Mice with Age-Related Memory Impairment.

Author

Davydova TV, Vetrile LA, and Zakharova IA

Subjects
Animals, Male, Mice, Administration, Intranasal, Avoidance Learning drug effects, Mice, Inbred C57BL, Aging, Antibodies, Glutamic Acid metabolism, Hippocampus metabolism, Hippocampus drug effects, Interleukin-6 metabolism, Interleukin-6 immunology, Memory Disorders drug therapy, Prefrontal Cortex metabolism, Prefrontal Cortex drug effects
Abstract

Intranasal administration of antibodies to glutamate for 14 days improved passive avoidance conditioning and reduces the content of IL-6 within 7 days after their withdrawal in the prefrontal cortex and hippocampus of aging C57BL/6 mice., (© 2024. Springer Science+Business Media, LLC, part of Springer Nature.)

Published
2024
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