Antibodies to Glutamate Reduce the IL-6 Content in Cerebral Structures in Mice with Age-Related Memory Impairment.

Authors :: Davydova TV
Vetrile LA
Zakharova IA
Source :: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2024 Sep; Vol. 177 (5), pp. 607-609. Date of Electronic Publication: 2024 Sep 28.
Publication Year :: 2024
Abstract: Intranasal administration of antibodies to glutamate for 14 days improved passive avoidance conditioning and reduces the content of IL-6 within 7 days after their withdrawal in the prefrontal cortex and hippocampus of aging C57BL/6 mice.<br /> (© 2024. Springer Science+Business Media, LLC, part of Springer Nature.)

Subjects :: Animals
Male
Mice
Administration, Intranasal
Avoidance Learning drug effects
Mice, Inbred C57BL
Aging
Antibodies
Glutamic Acid metabolism
Hippocampus metabolism
Hippocampus drug effects
Interleukin-6 metabolism
Interleukin-6 immunology
Memory Disorders drug therapy
Prefrontal Cortex metabolism
Prefrontal Cortex drug effects

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