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Returnable packaging systems (RPS) related to consumer products help to reduce problematic plastic and glass waste in supply chains. The purpose of this paper is to investigate distribution and return processes and the related cost drivers and benefits of returnable packaging with a deposit refund system in retail stores. Through the lens of the actor–network theory and based on 30 interviews with store managers, including on‐site observations, we develop a research model that structures key processes of RPS and their input and output factors. By subsequently applying system dynamics modeling, we find that: (1) customers' process satisfaction, (2) price elasticity of demand, and (3) time between repeat purchases are key variables that impact RPS' attractiveness and performance. This research contributes to an in‐depth understanding of processes within RPS as well as interdependencies between cost drivers and benefits for retailers. From a managerial perspective, these insights can enable retailers to take action based on the influencing factors for efficient operations related to RPS. Finally, this research has policy implications as it provides argumentation for the commercial benefits of RPS for retailers aside from the overemphasized cost perspectives. [ABSTRACT FROM AUTHOR]

From the historical roots of metalworking to the forefront of modern nanotechnology, functional materials have played a pivotal role in transforming societies, and their influence is poised to persist into the future. Encompassing a wide array of solid‐state materials, spanning semiconductors to polymers, molecular crystals to nanoparticles, functional materials find application in critical sectors such as electronics, computers, information, communication, biotechnology, aerospace, defense, environment, energy, medicine and consumer products. This feature article delves into diverse instances of functional materials, exploring their structures, their properties and the underlying mechanisms that contribute to their outstanding performance across fields like batteries, photovoltaics, magnetics and heterogeneous catalysts. The field of structural sciences serves as the cornerstone for unraveling the intricate relationship between structure, dynamics and function. Acting as a bridge, it connects the fundamental understanding of materials to their practical applications. [ABSTRACT FROM AUTHOR]

Background: Quantitative risk assessment (QRA) for skin sensitization is used to derive safe use levels of sensitising fragrance ingredients in products. Post‐marketing surveillance of the prevalence of contact allergy to these ingredients provides relevant data to help evaluate the performance of these measures. Objectives: To determine a suitable patch test concentration for five fragrance materials that had hitherto not been tested on a regular basis. These concentrations are then to be used in a surveillance study with patch testing consecutive patients over an extended monitoring period. Materials and Methods: Furaneol, CAS.3658‐77‐3; trans‐2‐hexenal, CAS.6728‐26‐3; 4,8‐dimethyl‐4,9‐decadienal, CAS.71077‐31‐1; longifolene, CAS.475‐20‐7; benzaldehyde, CAS.10052‐7, were patch tested with other fragrance allergens in four clinics. Patch testing was conducted in three rounds, starting with the lowest concentrations of the five ingredients. The doses were increased in the subsequent rounds if no late‐appearing positive reactions and virtually no irritant reactions were reported. Results: Overall, 373 patients were tested. No positive allergic reaction was reported to the five ingredients. Patch test results of other fragrance allergens are reported. Conclusions: The highest test concentrations are each considered safe for patch testing consecutive patients. Further surveillance based on these preparations will evaluate the hypothesis that QRA‐driven consumer product levels of these fragrances can prevent sensitization. [ABSTRACT FROM AUTHOR]

We vary greatly in our perception of risk, not just because of differences between risks themselves, but also because of individual, contextual and cultural differences too. To better understand and predict responses to risk, we need to (a) integrate these components, combining approaches from different psychological disciplines and (b) also consider risk tolerance – how individuals trade-off between risks and benefits. We therefore developed an ICONS (individual, contextual, cognitive, social) framework; using it across two empirical studies (n = 4228) to examine how individuals perceive and respond to the quotidian risks associated with consumer products. Three dimensions underlined risk perceptions: benefits, dread and individual responsibility. Risk tolerance was typically predicted by interactions between individual (demographic, cultural worldview, personality) and contextual (product type/category, harm information) factors. In turn, perceived dread, benefits and individual differences shaped how likely participants were to communicate risk information. Our results demonstrate for the first time how the interaction between individual, cognitive (risk tolerance, intensity), contextual, and social (risk communication) factors is key to understanding and predicting risk perceptions. Together, our findings help explain why societal responses to risks are often difficult to predict and have implications for the spread, and amplification, of risk information. [ABSTRACT FROM AUTHOR]

Child impeding packs are difficult for children to open so protect them from unintended access to hazardous contents inside the pack. However, if packs are difficult for adults to open, in normal usage scenarios, this may result in a higher occurrence of packs being left open. This research explores differences in ease of usage and closure compliance between two types of child impeding packs of liquid laundry detergent capsules. The two packs, "Pinch & Lift" and "Press & Lift", had different opening and closing mechanisms. "Press & Lift" also included an audible "click" signal to confirm complete closure to the user. The research was performed across two studies. In both studies, the packs were used in participants' homes according to their usual storage and usage practices as replacements to their current liquid laundry detergent capsule pack. All participants had small children living with them in their household. In Study 1, self-reported closure and ease of use data was collected from 99 adult participants in Germany. They used each package in their home for 10 days. Study 2 extended Study 1 by measuring closure rates with an objective assessment using in pack sensors for a 10-day period for each pack. Self-reported closure and ease of use data were also collected. Study 2 was conducted with 87 participants in the United Kingdom. Results across both studies showed "Press & Lift" with the audible "Click" close signal to be rated by participants to be significantly easier to open and close and have a higher self-reported closure rate than "Pinch & Lift". In addition, Study 2 results demonstrated higher closure rates using "Press & Lift" based on the sensor-measured closure compliance. Together, the results suggest transition to a pack with a mechanism that is child impeding and easier for an adult to use with an audible closure signal, like the "Press & Lift" system, has potential to reduce child access to a capsule from a pack by reducing the likelihood of the pack being left open by the adult user. Ultimately, such packs could protect children from potential poisoning injury across a range of consumer products. [ABSTRACT FROM AUTHOR]

Di-iso-nonyl phthalate (DINP) and di-iso-decyl phthalate (DIDP) have been employed increasingly as plasticizers to replace di-(2-ethylhexyl) phthalate (DEHP), a hormonal disruptor. Through this systematic review, we reviewed their (1) contamination levels in the environmental media, foods, and consumer products, (2) human exposure levels in national biomonitoring studies, and (3) associations with human sex and thyroid hormone disruption. PubMed, Scopus, and Web of Science were searched and eligible studies were identified. DINP and DIDP were found at higher concentrations in indoor environments, especially with high human activity and PVC use. In foods, contamination levels vary by production methods and tend to be higher in fatty foods. In children's products, both plasticizers were more highly detected in samples measured before 2010. National biomonitoring data from several countries demonstrated that urinary levels of DINP and DIDP metabolites were relatively lower than those of DEHP. However, exposure to DINP has been associated with anti-androgenic potential in male offspring and adults and decreased thyroid hormones in mother–child pairs. In conclusion, existing literatures demonstrated widespread occurrence of DINP and DIDP in the indoor environment, diet, and children's products, and in the human populations worldwide. At the current levels of exposure, DINP exhibited endocrine disruption potentials similar to those of DEHP, especially among males and pregnant women. Knowledge gaps in DIDP exposure among the human population were identified and should be considered for future studies. [ABSTRACT FROM AUTHOR]

The article discusses the right to repair and its potential effects on the circular economy. Other topics include how the right to repair movement create challenges for producers and designers of consumer products, as well as the responses made by companies to class action lawsuits, changing consumer demands, and the adoption and growth of environmental, social, and governance (ESG) principles.

As e‐commerce emerges as a central mechanism through which customers make purchases, so does the diversity of products they choose to purchase online. One of the fastest‐growing product categories is that of large and oversized items, often referred to as "big and bulky" items. This trend is particularly pronounced in the United States, with the online appliance and furniture markets experiencing substantial growth. Significant growth is also observed in the last‐mile delivery services sector for these large items. This presents a plethora of opportunities for industry stakeholders. Capitalizing on these opportunities and achieving service differentiation requires significant strategic investments in specialized equipment and capabilities by retailers and logistics service providers. These capabilities differ significantly from those typically required to deliver standard consumer products. This shift in operational context requires a deep understanding of customer preferences regarding big and bulky item delivery services. In this study, we determine customer preferences for big and bulky item delivery service features and quantify the effect of customer psychographic traits on those preferences. We accomplish this by conducting a choice‐based conjoint experiment. Our findings indicate significant effects that bear both research and managerial implications. [ABSTRACT FROM AUTHOR]

Cyclic and linear siloxanes are compounds synthesized from silicon consisting of alternating atoms of silicone and oxygen [Si-O] units with organic side chains. The most common cyclic siloxanes are octamethylcyclotetrasiloxane (D4), decamethylcyclopentasiloxane (D5), and dodecamethylcyclohexasiloxane (D6), while the most common linear siloxanes are high molecular weight polydimethylsiloxanes (PDMS) and low molecular weight volatile linear siloxanes known as hexamethyldisiloxane (L2), octamethyltrisiloxane (L3), decamethyltetrasiloxane (L4), dodecamethylpentasiloxane (L5). These compounds (1) exhibit low dermal toxicity, (2) are generally inert and non-reactive, and (3) are compatible with a wide range of chemicals offering beneficial chemical properties which include the following: wash-off or transfer resistance from the skin, sun protection factor (SPF) enhancement, emolliency in cleaning products). Because of these properties, these compounds are incorporated into multiple consumer products for use on the skin, such as cosmetics and health-care products, with over 300,000 tons annually sold into the personal care and consumer products sector. Because of their widespread use in consumer products and potential for human dermal exposure, a comprehensive understanding of the dermal absorption and overall fate of siloxanes following dermal exposure is important. This review summarizes available data associated with the dermal absorption/penetration as well as fate of the most commonly used siloxane substances. [ABSTRACT FROM AUTHOR]

Summary: While consumers are increasingly used to purchasing online, virtual reality (VR) is well acknowledged to enhance consumer experience via immersive and interaction systems. In our research, we recruited 160 participants (80 per experiment) to compare their consumer experiences of choosing Fast‐Moving Consumer Goods (FMCGs) in a virtual store (via VR) and on an online webpage. Specifically, each participant was asked to choose four FMCGs (foods in Experiment 1 and non‐foods in Experiment 2) for the next 4 weeks, and they filled out the Positive and Negative Affect Scale before and after completing choice tasks. Results of the anova showed that there was a significant decrease in negative affect scores following both food and non‐food choices (Mbefore = 1.3 vs. Mafter = 1.2). Positive affect ratings were significantly higher for food choices in VR than online (MVR = 2.5 vs. Monline = 2.1), with no significant difference for non‐food choices. This highlights the impact of VR on food choice and its potential to transform human–food interactions. The study reveals that VR can narrow the gap between consumers' expectations and actual perceptions by creating an immersive and interactive shopping experience, thus significantly influencing consumer behaviour. [ABSTRACT FROM AUTHOR]

Flexible polyurethane foams (PUF) are used in many consumer products. PUF may contain trace levels of aromatic diamine impurities that could represent a potential health risk. The risk associated with sleeping on a PUF mattress was evaluated. Toxicity benchmarks for sensitization and non-cancer endpoints were derived from the respective points-of-departure using standard assessment factors. For the cancer endpoints, toxicity benchmarks were derived from the 25th-percentile values of animal studies. Recently published emission and migration data allowed to link exposure with the CertiPURTM voluntary quality limits of ≤5 mg.kg−1 for 2,4-toluene diamine and 4,4'-methylene dianiline in PUF. Using conservative exposure scenarios, lifetime-average daily internal doses from the combined inhalation and dermal exposures were calculated. Margins of safety for non-cancer and sensitization endpoints were >104. The theoretical excess cancer risk was ≤1.5 × 10−7. It is concluded that sleeping on a mattress that satisfies the CertiPUR limit value does not pose undue risk to consumers. [ABSTRACT FROM AUTHOR]

We combine nonparametric price response modeling and dynamic pricing. In particular, we model sales response for fast-moving consumer goods sold by a physical retailer using a Bayesian semiparametric approach and incorporate the price of the previous period as well as further time-dependent covariates. All nonlinear effects including the one-period lagged price dynamics are modeled via P-splines, and embedding the semiparametric model into a Hierarchical Bayesian framework enables the estimation of nonlinear heterogeneous (i.e., store-specific) immediate and lagged price effects. The nonlinear heterogeneous model specification is used for price optimization and allows the derivation of optimal price paths of brands for individual stores of retailers. In an empirical study, we demonstrate that our proposed model can provide higher expected profits compared to competing benchmark models, while at the same time not seriously suffering from boundary problems for optimized prices and sales quantities. Optimal price policies for brands are determined by a discrete dynamic programming algorithm. [ABSTRACT FROM AUTHOR]

Background When detecting Salmonella spp. in food samples, unlike with culture-based procedures where there are solid standards, PCR techniques are generally dominated by commercial solutions, often backed by the conformity of reference organizations, and based on rigorous validation studies. The few independent standards that exist are not subject to revision and improvement to the same extent as the manufacturer's methods. Moreover, since commercial networks do not promote them, they are implemented less in everyday practice. The German standard DIN 10135 is an example of this. In this method, before PCR detection, a primary enrichment (16–20 h) followed by a secondary selective enrichment of at least 6 h is needed. Nevertheless, it allows the possibility of only applying the first step if evidence of their correct operation is provided. Objective To evaluate how necessary is the secondary enrichment for DIN 10135 standard. Methods Short and complete enrichment steps were compared in the context of the evaluation of the limit of detection for 11 types of food. Additionally, a blind assay was performed with 75 food samples. Results The data show that a simple primary enrichment may be sufficient and that the second selective enrichment with the tested matrixes would not be strictly essential. The blind study obtained a 98.6% of trueness and precision of 100%. Conclusions At least for the end consumer products, a secondary enrichment of 6 h is not necessary for all the products tested. Highlights In the context of the DIN 10135 standard, the primary enrichment (16–20 h, 37 ± 1°C) can be enough for detecting Salmonella spp. [ABSTRACT FROM AUTHOR]

The core objective of a successful product supply strategy is to determine the mechanism through which consumers' psychological effects influence customer demand. As stated in the theory of supply and demand, a higher level of dynamic equilibrium should be formed in which demand drives supply and supply creates demand. There is a lack of systematic research in the literature on the identification of consumer goods demand attributes and the formation of influencing factors in consumer goods supply chains. In this paper, we use the literature on demand functions and product pricing functions to establish three mathematical models to study the factors that influence retailers in designing and planning product supply strategies for different customers under nonessential demand patterns and to solve the profit maximization problem. The results of numerical examples validate the validity of the model. The research results can help retailers develop different supply strategies according to different types of customers and different demand patterns, thereby improving business performance. The theoretical contribution of this study is the construction of value ranges and a demand function diagram for identifying consumer product demand attributes. [ABSTRACT FROM AUTHOR]

Current calls for deep societal transformation stress the need to go beyond green consumption and aim for the reduction of material consumption. Such a shift is enacted by grassroots initiatives around reuse, repair and sharing. However, the possibility of postconsumerist perspectives and practices to reach a broader audience is affected by discursive opportunity structures (DOS) formed in public debate. To understand the DOS it is relevant to pay attention both to the continuous normalisation of consumption and to the ways in which alternatives are represented. To develop new analytical tools for examining what postconsumerist initiatives are up against, we introduce the concept of banal consumerism : mundane, habitual expressions that reproduce consumer culture. Through an empirical study of Swedish daily newspapers, we construct the basis for a typology of different expressions of banal consumerism. We find several expressions, of which the massive advertising of consumer goods is the most common but editorial material also plays an important role. This largely disabling DOS is then put in relation to the potentially enabling opportunities entailed in the existing media coverage of postconsumerist initiatives, practices and perspectives. The results show that postconsumerist initiatives and practices are newsworthy and presented as commendable. The fact that high levels of material consumption negatively impact the environment and life on the planet is widely accepted. To argue for degrowth or criticise consumerism is, however, controversial. Thus, support for postconsumerist practices coexist with massive expressions of banal consumerism, creating a complex set of DOS for the postconsumerist initiatives to navigate. [ABSTRACT FROM AUTHOR]

After a disaster, the population undertakes a series of actions aimed at saving and rescuing other people who may be in danger, as well as the gathering of goods considered indispensable to ensure their safety. Numerous studies have indicated that gender is one of the factors that conditions the lived experience of a disaster and, therefore, the actions that people undertake during the emergency. However, previous studies addressing the issue of gender in this respect have focused on how people are evacuated from the danger area, rather than on the rescue of goods. With the aim of contributing to filling this gap, the current article studies the patterns of the reproduction of/alteration in gender roles in the rescue of material goods following the earthquake in Lorca (Spain) in 2011 through the analysis of raw data collected from four focus groups comprising people who survived this catastrophic event. The results demonstrate that during the rescue actions in the disaster the men and women studied behaved to a great extent in line with traditional gender roles, although there were certain actions undertaken that involved a degree of alteration to these roles. [ABSTRACT FROM AUTHOR]

This research was conducted to determine the influence of managerial ownership, audit committee, profitability and tax avoidance on company value in manufacturing companies in the consumer goods sector for the 2018-2022 period. This research uses a purposive sampling model and the population in this research is manufacturing companies in the consumer goods sector, totaling 16 companies listed on the Indonesia Stock Exchange (BEI) for the 2018-2022 period that meet the criteria. The data analysis model used is panel data regression analysis. The research results in this study show that simultaneously the variables Managerial Ownership, Audit Committee, Profitability and Tax Avoidance have no influence on Company Value. However, partially the variables Managerial Ownership, Audit Committee, and Tax Avoidance do not have a significant influence on Company Value. Meanwhile, Profitability (ROA) has a significant influence on Company Value. [ABSTRACT FROM AUTHOR]

The aim of this research is to examine how competent the impact of capital structure and intangible assets is to company value which is moderated by managerial ownership. The views in this research use secondary data sourced from annual reports of companies in the consumer goods industry sector for 2018 - 2022 with a sample size of 110 company data which will then be examined using the eviews 12 statistical test. The results of the data testing state that capital structure have a negative effect on company value. Intangible assets has no effect on company value. Managerial ownership does not moderate capital structure on firm value. Managerial ownership does not moderate intangible assets on company value. Capital structure and intangible assets influance company value. [ABSTRACT FROM AUTHOR]

Nanomaterials are integrated within consumer products to enhance specific properties of interest. Their release throughout the lifecycle of nano-enabled products raises concerns; specifically, mechanical strains can lead to the generation of fragmented materials containing nanomaterials. We investigated the potential release of single-walled carbon nanotubes (SWCNTs—brand TUBALL™) from epoxy composite materials. A pin-on-disk-type tribometer was used for the accelerated mechanical aging of the nanocomposites. A pristine nanocomposite material, abraded material and debris obtained from the abrasion in the tribometer were analyzed by Raman spectroscopy. The airborne-produced particles were captured using particle collectors. Stat Peel's Identifier C2 system was used to monitor the SWCNT content of respirable particles produced during the abrasion test. The SWCNT amounts found were below the LoQ. The Raman spectra conducted on the Stat Peel filters helped identify the presence of free SWCNTs released from the epoxy matrix, although they were notably scarce. Raman spectroscopy has been proved to be a crucial technique for the identification, characterization and assessment of structural changes and degradation in SWCNTs that occurred during the abrasion experiments. [ABSTRACT FROM AUTHOR]

Pharmacists and pharmacies are key drivers in the American marketplace. They serve as an endpoint of the pharmaceutical supply chain and are the dispensers of a range of consumer goods, some nonthreatening and others potentially harmful to public health. In adding pharmacies to the roster of consumerist locales in the postwar period, scholars might draw even deeper connections about the transformation of health, corporate medicine, and American economic power. To understand the interface of consumerism, corporatism, and health in postwar America, this article holds the postwar pharmacy as a key site of commodity exchange and business and positions it within the larger American firmament, paying attention to the design of pharmacies. In particular, the article will add to the knowledge about the tangible ways that medical and health care spaces are constructed, organized, and designed to best generate profits. Besides prescription medications, alcohol, tobacco, and sugar-rich products were also vital elements of the postwar pharmacy and will be featured in this article. What is more, this article focuses on a central debate between pharmacists during the postwar period about how pharmacies were shifting from the role of healer to that of a retailer — from a "conscientious guardian" to a "commercialized jungle" — in order to highlight how the public health role of pharmacies was undermined by industry pressures for profit. Based on unused corporate guides and manuals, company records, photographs, and management documents, this article will spotlight the underexplored interiority of pharmacies – the store's insides, processes of organization, and design features related to potentially habit-changing substances. [ABSTRACT FROM AUTHOR]

In this contribution, we introduce 'career hubs' as an alternative to interlocking directorates and propose to study transnational corporate elite networks with this new concept. Career hubs, the most frequent common career organizations, put emphasis on knowledge brokering and allow us to study a larger variety of organizations to understand the form and the spread of elite networks. We use a sample of 1366 firms on the Forbes 2000 list of 2018 and investigate the careers of 16,500 top executives by linking these data to the BoardEx database. We find three types of career hubs: global audit and consulting firms, financial firms participating in a transatlantic banking alliance and large US consumer goods conglomerates – and highlight the mechanisms through which they shape the spatial structures of finance led capitalism. In the conclusion, we consider the implication of our results for the literature on corporate networks and propose a series of future research avenues in the career hub perspective. [ABSTRACT FROM AUTHOR]

In recent decades, the versatility of fossil-based polymers has led them to become one of the most used materials for the production of several consumer goods. The destiny of post-consumer plastics is crucial for environmental sustainability. Two are the alternatives to landfilling: (i) energy recovery, i.e., replacement of traditional fuel with plastic litter, and (ii) recycling, i.e., processing of plastic wastes to produce secondary raw materials that may substitute primary raw materials. This work presents the investigation of a device for the hydraulic separation of heterogeneous plastic wastes, which, when properly upscaled, may be efficiently used within recycling plants. This apparatus is suitable for the separation of granules or flakes of plastics with a density higher than 1000 Kg/m3 and may replace existing technologies for mechanical recycling. The purpose of the device is to separate the useful fraction from a mixture of plastics and water introduced inside. The separation procedure efficacy relies on the difference in density, dimension, and shape of the processed plastic particles and on the flow features within the device. Experiments were carried out to test the efficacy of the device as a function of those factors. To increase the range of variation in the key parameters influencing the apparatus's working principles, Computational Fluid Dynamics was employed to build a numerical model of the device. The validated numerical model suitable to fully characterize the apparatus performance features a hybrid grid with an inner mesh of 3·10−3 m size, a careful modeling of the near-wall region, and the k-ω SST turbulent model. [ABSTRACT FROM AUTHOR]

Pressure-sensitive adhesive tapes may be associated with a wide range of criminal and terrorist activity as physical evidence. In this study, a carbon powder suspension formulation for the detection of latent fingermarks on the adhesive side of tapes was modified by using consumer products as alternative surfactant sources. The modified formulations were used to successfully develop latent fingermarks deposited on transparent adhesive tape. This project ultimately intends to establish the performance windows of the modified techniques to allow evidence-based decision-making during technical exploitation in contested and austere environments. [ABSTRACT FROM AUTHOR]

Pressure-sensitive adhesive tapes may be associated with a wide range of criminal and terrorist activity as physical evidence. In this study, a carbon powder suspension formulation for the detection of latent fingermarks on the adhesive side of tapes was modified by using consumer products as alternative surfactant sources. The modified formulations were used to successfully develop latent fingermarks deposited on transparent adhesive tape. This project ultimately intends to establish the performance windows of the modified techniques to allow evidence-based decision-making during technical exploitation in contested and austere environments. [ABSTRACT FROM AUTHOR]

"The Apple II Age: How the Computer Became Personal" by Laine Nooney challenges the popular Silicon Valley narrative of computing's rise as a product of counterculture visionaries. Instead, Nooney argues that personal computing was driven by financial interests rather than a desire for social revolution. The book explores the history of the Apple II computer, highlighting its hardware and software innovations, such as the VisiCalc spreadsheet program and games like Mystery House. Nooney emphasizes the importance of selling the Apple II and the role of connections to investors and sources of capital in its success. The book provides a nuanced and antideterministic perspective on the history of computing, disrupting the techno-utopian narrative often associated with it. [Extracted from the article]

Phthalate esters (PAEs) are widely used as plasticizers to enhance the flexibility and durability of different consumer products, including clothing. However, concerns have been raised about the potential adverse health effects associated with the presence of phthalates in textiles, such as endocrine disruption, reproductive toxicity and potential carcinogenicity. Based on examination of more than 120 published articles, this paper presents a comprehensive review of studies concerning the phthalate content in clothing and other textile products, with special emphasis on those conducted in the last decade (2014–2023). The types and role of PAEs as plasticizers, the relevant legislation in different countries (emphasizing the importance of monitoring PAE levels in clothing to protect consumer health) and the analytical methods used for PAE determination are critically evaluated. The review also discusses the models used to evaluate exposure to PAEs and the associated health risks. Finally, the study limitations and challenges related to determining the phthalate contents of textile products are considered. [ABSTRACT FROM AUTHOR]

Benzisothiazolinone (BIT) and propyl paraben (PP) are preservatives in cleaning products; however, their toxicities are not well understood. In this study, zebrafish embryos were exposed to BIT, PP, and mixtures of both for 96 h to investigate the effects on growth hormone (GH), insulin-like growth factor-1 (IGF-1), and the transcription of 19 genes related to the GH/IGFs axis. Concentrations of BIT and PP were measured in the whole body of larvae. Zebrafish pairs were also exposed to BIT, PP, and mixtures for 21 d to evaluate the effects on sex hormones, histology in gonad, and transcription of 22 genes related to the hypothalamus-pituitary-gonad axis and vitellogenin. The mixtures had potentiation effects on development, reproduction, hormones, and gene transcripts than individual exposure. Larvae exposed to 229 μg L−1 BIT, 64.5 μg L−1 PP, and mixtures showed reduced growth. Decreased GH and IGF-1 levels were supported by gene regulation associated with the GH/IGFs axis. In larvae, reactive oxygen species, superoxide dismutase, catalase, and glutathione peroxidase levels were increased under all exposures. The gonadosomatic index in males and number of eggs decreased after mixture exposure. In females exposed to mixtures, the percentage of atretic follicle in ovary was significantly increased. The significant decrease in testosterone in males and significant decrease in 17β-estradiol in females exposed to mixtures suggest anti-estrogenic and anti-androgenic potential. Thus, preservative mixtures in consumer products may be more toxic than the individual substances, which is important for managing the risks of mixing preservatives. [Display omitted] • Toxicity of BIT and PP was evaluated considering the content ratio in the product. • Embryonic development of zebrafish was inhibited at 229 μg L−1 BIT and 64.5 μg L−1 PP. • BIT and PP mixture decreased GH and IGF-1 and increased oxidative stress in larvae. • Anti-estrogenicity and anti-androgenicity were observed in fish exposed to mixtures. • The adverse effects were more prominent for mixtures than for individual chemicals. [ABSTRACT FROM AUTHOR]

This study proposes a simulation model for allocating counterbalanced forklifts in a logistics distribution center (LDC) with aisle constraints. Modeling the case study for a consumer goods firm, the performance measures of the logistics operation were calculated and certain experimental scenarios were purposed for decision-making regarding the number of forklifts and their productivity. The relevance of this research is validated by the gap in existing literature on enhancing forklift assignments in massive storage systems with restrictions. The simulation scenarios contribute toward standardizing logistics operations with similar characteristics, starting from the layout stage of an LDC. The designed simulation model demonstrates that the simulated allocation incorporates technical and human resources in warehouse operations. Utilizing discrete-event simulation (DES) as a framework, this study assesses various scenarios in an LDC with restrictions on the forklift. The hypothesis of the problem was analyzed, and the simulation model was used to characterize the system behavior under different scenarios and guide the decision-making processes impacting operational costs and client service levels. This research employs DES to address performance indicators and operational costs, serving as a methodological guide for resource allocation in logistics operations at distribution centers. [ABSTRACT FROM AUTHOR]

The Modernization of Cosmetics Regulation Act of 2022 (MoCRA) amends the Food, Drug and Cosmetic Act (FDCA), elevating the standard of proof of safety (better known as a "safety standard") for cosmetics to the standard of a "reasonable certainty ... [of] ... safe."a standard equal to that of food ingredients. The standards of the proof of safety differ for various classes of FDA-regulated product categories e.g., cosmetics, dietary supplements, food ingredients and food itself. This manuscript describes the various standards of proof, the essential differences between the standards, key elements required to achieve a particular standard and, compares the standards to more familiar legal terms such as "a preponderance of the evidence" or "beyond reasonable doubt." The standards of proof for these product categories are also ranked according to increasing threshold for achievement of "safe" status. Lastly, this manuscript suggests how the requirements for the high standard of a "reasonable certainty of safe" (or "reasonable certainty of no harm") might be met. • Modernization of Cosmetics Regulation Act of 2022 and new safety requirements. • How various categories of FDA regulated products are judged for safety. • Safety categories explained in more familiar terms, such as preponderance of evidence. • Items to consider in producing a document to the standard of proof of "reasonable certainty of no harm". [ABSTRACT FROM AUTHOR]

Development of New Approach Methodologies (NAMs) capable of providing a No Expected Sensitization Induction Level (NESIL) value remains a high priority for the fragrance industry for conducting a Quantitative Risk Assesment (QRA) to evaluate dermal sensitization. The in vi tro GARDskin assay was recently adopted by the OECD (TG 442E) for the hazard identification of skin sensitizers. Continuous potency predictions are derived using a modified protocol that incorporates dose-response measurements. Linear regression models have been developed to predict human NESIL values. The aim of the study was to evaluate the precision and reproducibility of the continuous potency predictions from the GARDskin Dose-Response (DR) assay and its application in conducting QRA for fragrance materials using a Next Generation Risk Assessment (NGRA) framework. Results indicated that the GARDskin Dose-Response model predicted human NESIL values with a good degree of concordance with published NESIL values, which were also reproducible in 3 separate experiments. Using Isocyclocitral as an example, a QRA was conducted to determine its safe use levels in different consumer product types using a NGRA framework. This study represents a major step towards the establishment of the assay to derive NESIL values for conducting QRA evaluations for fragrance materials using a NGRA framework. • Developed a Next Generation Risk Assessment (NGRA) framework for conducting QRA2 for fragrance materials. • The GARDskin Dose Response (DR) assay is a reliable and reproducible method for predicting NESIL for fragrance materials. • NGRA for QRA2 was validated using isocyclocitral as a case study. [ABSTRACT FROM AUTHOR]

The entire world is committed to maintaining the 1.5 °C global temperature rise target in order to avoid very serious impacts of climate change. However, because the food sector is one of the primary contributors of GHG emissions, the environmental impact of food products is now a new criterion for consumer product selection, and this includes milk. The current review investigates the state of the art of the environmental impact of animal-based milk (ABM) (cow, buffalo, goat, and sheep) and plant-based milk (PBM) (almond, oat, soy, pea, and coconut) systems using 70 milk life cycle assessment (LCA) studies. The critical review aims to produce two primary deliverables concerning the environmental impact of ABM and PBM. The first section is concerned with generating a universal LCA framework for ABM and PBM systems, as well as the recalculation of collated results to standardize and synthesize a full comparison of AM and PBM based on several eco indicators and presents a hierarchy of environmentally sustainable milk. From the synthesis of results, it was observed that the lowest mean of global warming potential (GWP) in ABM is cow milk, and in PBM is coconut milk, i.e., 1.29 and 0.257 kg CO 2 /kg of milk, respectively. The second section highlights the comparative effects of assumptions for LCA system functions i.e., system boundaries and impact allocation methodology, with critical insights. Apart from that, the current review also investigates the hotspots in ABM and PBM systems, presents the priority order of processes for the mitigation measures, and provides multiple mitigation strategies and their effect. The authors also identify challenges and future research areas to make dairy and nondairy milk systems more environmentally sustainable. [Display omitted] • 70 LCA and CF studies were reviewed of animal and plant-based milk (PBM) systems. • The environmental impact of animal and plant-based milk systems was thoroughly compared. • Environmental aspects of the PBM system are relatively unexplored and require rigorous evaluation. • GHG emissions from PBM are low, but water footprints are high compared to cow's milk. • Hotspots of animal milk: enteric fermentation, animal feed, manure, PBM: processing, packaging, transport. [ABSTRACT FROM AUTHOR]

[Display omitted] • SP-ICP-MS can be used to estimate the size of carbon-based particles in the range of 2 – 4 µm. • SP-ICP-MS can be used to estimate numbers of carbon-based particles by using correction method. • Particle washing method can effectively purify the polystyrene particles from their suspending medium. • Carbon-based particles released from teabag and disposable mask in the size range of 1 – 2 µm were observed. A method based on single particle inductively coupled plasma mass spectrometry (SP-ICP-MS) with the use of regular sample introduction system was developed for the study of microplastics released from consumer products. With the standard type nebulizer used in SP-ICP-MS, the effect of sample introduction rate was evaluated and the flow rate of 0.18 mL min−1 was selected for further use. Under this condition, the transport efficiency was determined by using a commercially available uniform size of 50 nm AuNPs, and the calibration graph was constructed by using sucrose as dissolved forms of carbon. With this calibration approach, size analysis of polystyrene particles in the range of 1 – 6 µm was performed with the size detection limit of approx. 400 nm. The SP-ICP-MS was then applied to determine the particle size of laboratory synthesized polystyrene latex. The sizes obtained were found to positively deviate from the reference sizes reported by scanning electron microscopy (SEM), suggesting the potential problem from matrix interferences. Therefore, particle washing method by using deionized water was proposed to purify the polystyrene particles from their suspending medium. After particle washing, the sizes obtained from SP-ICP-MS with correction factor agreed well with the reference sizes. Therefore, the SP-ICP-MS method was applied to investigate the microplastics released from teabags and disposable face masks with the results compared with those from dynamic light scattering (DLS) and SEM. [ABSTRACT FROM AUTHOR]

Product development is often an important component in increasing demand for successful aquaculture species. However, this topic has not received much attention due to limited data availability. In this paper, we investigate how the composition of salmon sales differ by product form by comparing the four largest European countries in terms of salmon consumption: France, Germany, Spain and the United Kingdom. The composition of salmon products varies significantly across countries, with unprocessed products dominating in Spain and highly processed products being the most important in the United Kingdom. We also find a high degree of price transmission for the less processed consumer products in all markets, while the price transmission is zero for most highly processed products. This is important since it implies that the more processed consumer products are largely are insulated from the high price volatility of salmon at the producer level. • The composition in terms of product forms being sold varies significantly between major European salmon markets • Price transmission is high for relatively unprocessed products and low for processed products in all markets • Demand is more stable in markets with a higher market share for processed product forms • More processed consumer products are largely are insulated from the high price volatility of salmon at the producer level [ABSTRACT FROM AUTHOR]

Plastics have a significant role in various sectors of the global economy since they are widely utilized in agriculture, architecture, and construction, as well as health and consumer goods. They play a crucial role in several industries as they are utilized in the production of diverse things such as defense materials, sanitary wares, tiles, plastic bottles, artificial leather, and various other household goods. Plastics are utilized in the packaging of food items, medications, detergents, and cosmetics. The overconsumption of plastics presents a significant peril to both the ecosystem and human existence on Earth. The accumulation of plastics on land and in the sea has sparked interest in finding ways to breakdown these polymers. It is necessary to employ suitable biodegradable techniques to decrease the accumulation of plastics in the environment. To address the environmental issues related to plastics, it is crucial to have a comprehensive understanding of the interaction between microorganisms and polymers. A wide range of creatures, particularly microbes, have developed techniques to survive and break down plastics. This review specifically examines the categorization of plastics based on their thermal and biodegradable properties, as well as the many types of degradation and biodegradation. It also discusses the various types of degradable plastics, the characterization of biodegradation, and the factors that influence the process of biodegradation. The plastic breakdown and bioremediation capabilities of these microbes make them ideal for green chemistry applications aimed at removing hazardous polymers from the ecosystem. [Display omitted] • Recent advances in the microbial and enzymatic degradation of synthetic plastics. • Individual and combinatorial degradation of petro-plastics for low-carbon economy. • Employment of isolated and mutant enzymes to enhance the efficiency of biodegradation. • Existing approaches & assays for degradation assessment based on varying properties. • Potent hazards of fragmented plastic, micro- and nanoplastics to the living beings. [ABSTRACT FROM AUTHOR]

Consumer goods volume and their consumption structure significantly contribute to water pollution within economic zones. However, there remains a need to better comprehend the nuanced and seasonal nonlinear relationship between consumer goods and water pollution, which currently obstructs essential consumption adjustments aimed at reducing water pollution. This study selected an effective machine learning model Light Gradient Boosting Machine (LightGBM) with SHapley Additive Explanations (SHAP) to assess the nonlinear relationship between consumer goods and water pollution during flood and non-flood seasons within the Yangtze River Economic Belt from 2013 to 2022, Baidu Index of consumer goods were used to represent the potential consumption level (PCL). The findings revealed the following: (1) During flood seasons, hydroelectricity and the PCL of furniture and cultural goods emerged as factors driving water pollution reduction. Conversely, GDP, PCL of communication devices, and beverages played significant roles in exacerbating water pollution. During non-flood seasons, the drivers for reducing water pollution included GDP, income gap and PCL of cultural goods. Meanwhile, PCL of cars, western medicine and oil became pivotal drivers for exacerbating water pollution. (2) Concerning consumption structure during flood and non-flood seasons, maintaining consumption levels of costume industrial goods, cultural, sports and health goods and transportation and accommodation goods below 66.71%, 77.66% and 79.61% respectively of their average PCL appeared beneficial in reducing water pollution. During flood seasons, consumption levels of cars and furniture below 85.69% and 91.46% respectively of their average PCL were associated with reduced water pollution. During non-flood seasons, consumption levels of cars and oil below 82.95% and 71.28% respectively of their average PCL could help reduce water pollution. (3) The proportion of hydroelectricity generation exceeding 2% and 3% respectively during flood and non-flood seasons helped in reducing water pollution. Moreover, GDP per capita surpassing 2388.82 and 2075.78 respectively during flood and non-flood season was preferable for reducing water pollution. These findings deepened our understanding of the nonlinear relationship and identify promising consumer goods and their consumption structure that could effectively aid in reducing water pollution from a consumption perspective. [ABSTRACT FROM AUTHOR]

The Research Institute for Fragrance Materials (RIFM) and Creme Global Cremeglobal.com partnered to develop an aggregate exposure model for fragrance ingredients. The model provides a realistic estimate of the total exposure of fragrance ingredients to individuals across a population. The Threshold of Toxicological Concern (TTC) and Dermal Sensitization Threshold (DST) were used to demonstrate the magnitude of low exposure to fragrance materials. The total chronic systemic, inhalation, and dermal 95th percentile exposures on approximately 3000 fragrance ingredients in RIFM's inventory were compared to their respective TTC or DST. Additionally, representative fragrance ingredients were randomly selected and analyzed for exposure distribution by product type (i.e., cosmetic/personal care, household care, oral care, and air care) and route of exposure. It was found that 76 % of fragrance ingredients fall below their respective TTC limits when compared to 95th percentile systemic exposure, while 99 % are below inhalation TTC limits. The lowest 95th percentile aggregate exposure by product type was from household care products, then air care, and oral care products. The highest exposure was from personal care/cosmetic products. The volume of use for most fragrance ingredients (63 %) was <1 metric ton, estimating that environmental exposure to fragrance ingredients is likely low. • The Creme RIFM Aggregate Exposure model provides a realistic estimate of exposure. • Aggregate exposure of approximately 3000 fragrance ingredients was assessed. • 76 % and 99 % of fragrance ingredients fall below the systemic and respiratory TTC. • Household care and air care products have the lowest exposures by product type. • Oral and personal care/cosmetic products have the highest exposures by product type. [ABSTRACT FROM AUTHOR]

Here, we report a comparative study of different sum parameter analysis methods for the extraction of per- and polyfluoroalkyl substances (PFAS) from manufactured consumer products, which can be measured by combustion ion chromatography (CIC). Therefore, a hydrolysis-based extraction method was further developed, which accounts for the addition of hydrolyzable covalently bound polyfluoroalkylated side-chain polymers (SFPs) to the extractable organic fluorine portion of the mass balance proposed as "hydrolyzable organically bound fluorine" (HOF). To test this hypothesis, the method was applied to 39 different consumer products containing fluoropolymers or monomeric PFAS taken from four different categories: outdoor textiles, paper packaging, carpeting, and permanent baking sheets. We also evaluated the method's efficiency by extracting four synthesized fluorotelomer polyacrylate reference compounds. The total fluorine (TF) and extractable organically bound fluorine (EOF) values were measured through CIC using established protocols. The TF values ranged from sub-ppb to %-levels, depending on the compound class. All samples showed results for hydrolyzed organofluorine (HOF) between 0.03 and 76.3 μg/g, while most EOF values were lower (

In 2013, California revised its upholstered furniture flammability standard TB 117–2013 to improve fire safety without the need for flame retardant (FR) chemicals. Subsequent legislation (SB 1019) required disclosure of FR content. In 2020 California expanded restriction on FR chemicals to include juvenile products and upholstered furniture (AB 2998). To monitor trends in FR use, and assess the effectiveness of the new regulations, we analyzed 346 samples from upholstered furniture (n = 270) and children's consumer products (n = 76), collected pre- and post-regulatory intervention for added FR chemicals (i.e., ∑FR > 1000 mg/kg). Upholstered furniture samples, collected from products before enactment of the new regulations, had a median FR concentration of 41,600 mg/kg (range: 1360–92,900 mg/kg), with 100% of the foam samples and 13.7% of the textile samples containing ∑FR > 1000 mg/kg. Firemaster formulations (FM 550 and FM 600), a mixture of triphenyl phosphate (TPHP), 2-ethylhexyl-2,3,4,5-tetrabromobenzoate (EH-TBB), bis(2-ethylhexyl)-3,4,5,6-tetrabromophthalate (BEH-TEBP) and a mixture of isopropyl- or tert-butyl-triphenyl phosphates (ITPs or TBPPs), were the most frequently detected FR (34%), followed by tris(1,3-dichloroisopropyl) phosphate (TDCIPP; 25%), TPHP with a mixture of polybrominated diphenyl ethers (BDE-47, 99, 100, 153 and 154; 20%) and tris(2-chloroethyl) phosphate (TCEP; 11%). Upholstered furniture components collected after enactment of the new legislation had a median FR concentration of 2600 mg/kg (range: 1160–49,800 mg/kg, outlier sample 282,200 mg/kg), with 11.9% of the foam samples and no textile samples containing ∑FR > 1000 mg/kg. Of these samples, tris(1-chloro-2-propyl) phosphate (TCIPP) was the most frequently detected FR (55%), followed by TDCIPP (30%) and Firemaster (FM 550, 15%). No PBDEs were detected in the post-regulatory intervention products. Our initial work on children's products showed 15% of the samples contained ∑FR > 1000 mg/kg. In our post- AB 2998 work, no regulated children's product components failed compliance (i.e., ∑FR > 1000 mg/kg). The data confirm successful adoption of the new regulations with most samples in compliance, demonstrating the efficacy of regulatory intervention. Given these results, environmental FR exposure is expected to decrease as older FR treated consumer products are replaced with FR free products. [Display omitted] • Flame retardants in consumer products decrease after new California regulation. • TCIPP was the most prevalent flame retardant in non-compliant products. • All children's products were compliant with California's new flame retardant ban. • This study demonstrates impact and efficacy of regulatory intervention. [ABSTRACT FROM AUTHOR]

BPA is used in a wide range of consumer products with very concern toxicological properties. The European Union has restricted its use to protect human health. Industry has substituted BPA by BPA analogues. However, there is a lack of knowledge about their impacts. In this work, BPA and 5 BPA analogues (BPS, BPAP, BPAF, BPFL and BPC) have been studied in classical SH-SY5Y and the alternative 3D in vitro models after 24 and 96 h of exposure. Cell viability, percentage of ROS, cell cycle phases as well as the morphology of the spheroids were measured. The 2D model was more sensitive than the 3D models with differences in cell viability higher than 60% after 24 h of exposure, and different mechanisms of ROS production. After chronic exposure, both models were more affected in comparison to the 24 h exposure. After a recovery time (96 h), the spheroids exposed to 2.5–40 µM were able to recover cell viability and the morphology. Among the BPs tested, BPFL>BPAF>BPAP and >BPC revealed higher toxicological effects, while BPS was the only one with lower effects than BPA. To conclude, the SH-SY5Y 3D model is a suitable candidate to perform more reliable in vitro neurotoxicity tests. [Display omitted] • Cytotoxicity of BPA analogues were assessed in the SH-SY5Y neuroblastoma cell line. • The sensitivity of SH-SY5Y 2D and 3D in vitro models was studied under BPs exposure. • BPFL>BPAF>BPAP>BPC had greater effects on both in vitro models than BPA and BPS. • 2D in vitro models demonstrated higher sensitivity than 3D models at 24 and 96 h. • Under chronic exposure both in vitro models demonstrated more toxic consequences. [ABSTRACT FROM AUTHOR]

New Approach Methodologies (NAMs) are a rapidly growing set of tools/methods for use food, drug, consumer product, or chemical safety assessment paradigms. The massive growth in NAMs tech development, publication, and legislation has been paralleled by a growing sense of frustration. The challenge of realizing the systems-level changes needed to catalyze the broad-scale adoption and use of NAMs is substantial. This Commentary asserts that these challenges may be less unique than perceived to date, and points to specific opportunities to learn from decades of experience (both positive and negative) from the Quality Improvement (QI) movement in the public health and healthcare arenas. Specific recommendations to inform and guide NAMs development are offered. • The NAM arena can learn from decades of experience in the public health and healthcare Quality Improvement movements. • Before selecting or implementing any NAM approach, users should first clearly define the desired system improvement. • Systems change requires iterative engagements within a complex, multi-stakeholder and multi-setting ecosystem. [ABSTRACT FROM AUTHOR]