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Researchers at the University of Leeds conducted a study on the association between metformin use and cardiovascular health in patients with Type 2 Diabetes Mellitus (T2DM). The study found that metformin use was linked to higher myocardial perfusion reserve (MPR) and improved survival rates in patients with T2DM. This multicenter study included 572 patients with T2DM, with 68% of them prescribed metformin, and concluded that metformin may have a positive impact on cardiovascular outcomes in this patient population. [Extracted from the article]

A recent study conducted at the University of Leeds focused on patients with diabetes mellitus (DM) and heart failure (HF) to assess the prevalence of silent ischemic heart disease (IHD) and coronary microvascular dysfunction (CMD). The research utilized cardiovascular magnetic resonance (CMR) to quantify these conditions and found that patients with DM and HF had a higher prevalence of silent IHD, evidence of CMD, and worse cardiovascular outcomes compared to non-diabetic patients with HF. The study highlights the potential value of CMR in assessing these conditions in patients with DM and HF. [Extracted from the article]