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A new report presents research on the incidence of eosinophilic esophagitis (EoE) in patients with inflammatory bowel disease (IBD). The study aimed to differentiate true EoE from esophageal eosinophilia in IBD patients by evaluating the expression of major basic protein (MBP) and interleukin-13 (IL-13) in esophageal biopsies. The results showed that MBP may be an excellent marker in distinguishing true EoE from eosinophilia caused by IBD. The researchers concluded that MBP, along with endoscopic and histologic changes, can assist in the diagnosis of EoE in IBD patients. [Extracted from the article]

A recent study conducted at Brigham and Women's Hospital in Boston, Massachusetts, explored the predictive value of baseline peripheral eosinophil counts (AECs) for proton pump inhibitor (PPI) response in eosinophilic esophagitis (EoE). The study found that baseline peripheral eosinophilia independently predicts PPI nonresponse and food impaction in EoE patients. This information may help guide therapy selection and prevent delays in achieving histologic remission. The study was published in the Journal of Clinical Gastroenterology and has been peer-reviewed. [Extracted from the article]