New Inflammatory Bowel Disease Findings from Division of Pediatric Gastroenterology Described (Major Basic Protein Is a Useful Marker To Distinguish Eosinophilic Esophagitis From Ibd-associated Eosinophilia In Children).

A new report presents research on the incidence of eosinophilic esophagitis (EoE) in patients with inflammatory bowel disease (IBD). The study aimed to differentiate true EoE from esophageal eosinophilia in IBD patients by evaluating the expression of major basic protein (MBP) and interleukin-13 (IL-13) in esophageal biopsies. The results showed that MBP may be an excellent marker in distinguishing true EoE from eosinophilia caused by IBD. The researchers concluded that MBP, along with endoscopic and histologic changes, can assist in the diagnosis of EoE in IBD patients. [Extracted from the article]