1. Recurrent Kaposi's varicelliform eruption in Darier's disease.
- Author
-
Higgins, P.G. and Crow, K.D.
- Subjects
DISEASE relapse ,KERATOSIS follicularis ,KAPOSI'S sarcoma ,VARICELLA-zoster virus ,SKIN disease genetics ,DISEASES in women ,HERPES simplex virus ,VIRUSES - Abstract
This paper describes five attacks of Kaposi's varicelliform eruption which occurred during a period of 18 months in a woman with Darier's disease. Herpes simplex virus type 1 was isolated from the lesions in three of the four episodes which were studied in the laboratory and Coxsackievirus type A16 from the remaining attack. It is suggested that Coxsackievirus A16 may be a hitherto overlooked cause of Kaposi's varicelliform eruption. Infection with any one of a number of viruses may be accompanied by vesicular lesions of the skin. Herpes simplex virus and vaccinia virus arc the two most frequently found affecting established skin disease, especially atopic eczema, when the term Kaposi's varicelliform eruption is commonly used to describe the condition. Hyperkeratosis follicularis, Darier's disease, is an uncommon dyskeratosis with a characteristic clinical and histological picture and may be complicated by secondary viral infection. In most of the published reports of Kaposi's varicelliform eruption in Darier's disease, herpes simplex virus has either been assumed to be the infecting agent (Bleiberg & Kiosk, 1951; Kesten, 1952; Hitselberger & Burns, 1961) or actually proven to be by virus isolation (von Weiss, Kibrick & Lever, 19655 Doeglas & Moolhuysen, 1969; Izumi & Goldschmidt, 1970). Infection with vaccinia virus has also been recorded (Gerstcin & Shelley, 1960). The purpose of this paper is to report the occurrence of five attacks of Kaposi's varicelliform eruption in a patient with Darier's disease within a period of 18 months, together with the virological findings. [ABSTRACT FROM AUTHOR]
- Published
- 1973