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1. Solid-supported catalysts for atom-transfer radical cyclization of 2-haloacetamides

Author

Clark, Andrew J., Filik, Robert P., Haddleton, David M., Radique, Arnaud, Sanders, Christopher J., Thomas, Gerard H., and Smith, Mark E.

Subjects
Chemistry, Organic -- Research, Ring formation (Chemistry) -- Research, Amides -- Research, Biological sciences, Chemistry
Abstract

Research has been conducted on the copper(I) halide complexes of silica-supported ligands to demonstrate that they are efficient cyclization mediators of activated and unactivated 2-haloacetamides. Experiments indicate that N-alkyl substituent affects catalyst efficiency.

Published
1999

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