Solid-supported catalysts for atom-transfer radical cyclization of 2-haloacetamides

Authors :: Clark, Andrew J.
Filik, Robert P.
Haddleton, David M.
Radique, Arnaud
Sanders, Christopher J.
Thomas, Gerard H.
Smith, Mark E.
Source :: Journal of Organic Chemistry. Nov 26, 1999, Vol. 64 Issue 24, p8954, 4 p.
Publication Year :: 1999
Abstract: Research has been conducted on the copper(I) halide complexes of silica-supported ligands to demonstrate that they are efficient cyclization mediators of activated and unactivated 2-haloacetamides. Experiments indicate that N-alkyl substituent affects catalyst efficiency.

Subjects :: Chemistry, Organic -- Research
Ring formation (Chemistry) -- Research
Amides -- Research
Biological sciences
Chemistry

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