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Your search keyword '"Kang, Yang Gyu"' showing total 8 results
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8 results on '"Kang, Yang Gyu"'

2. Immune-enhancing effects of Portulaca oleracea L.– based complex extract in cyclophosphamide-induced splenocytes and immunosuppressed rats

Author

Park, Young Mi, primary, Lee, Hak Yong, additional, Kang, Yang Gyu, additional, Park, Sang Hoon, additional, Lee, Bong Gun, additional, Park, Yeon Ju, additional, Oh, Hong Geun, additional, Moon, Dae In, additional, Kim, Young Pill, additional, Park, Deuk Seon, additional, Lee, Hyang Man, additional, Kim, Ok jin, additional, Yang, Hye-Jeong, additional, Kim, Min Jung, additional, and Lee, Young-Rae, additional

Published
2018
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3. Immune-enhancing effects of Portulaca oleracea L.– based complex extract in cyclophosphamide-induced splenocytes and immunosuppressed rats.

Author

Park, Young Mi, Lee, Hak Yong, Kang, Yang Gyu, Park, Sang Hoon, Lee, Bong Gun, Park, Yeon Ju, Oh, Hong Geun, Moon, Dae In, Kim, Young Pill, Park, Deuk Seon, Lee, Hyang Man, Kim, Ok jin, Yang, Hye-Jeong, Kim, Min Jung, and Lee, Young-Rae

Subjects
PORTULACA oleracea, CYCLOPHOSPHAMIDE, ASIAN medicine, RATS, KILLER cells, TRADITIONAL medicine
Abstract

Portulaca oleracea L. is a traditional oriental medicine known for its pharmacological effects. The present study aimed to investigate the immunostimulatory effects of PPCE on cyclophosphamide-stimulated rat model and in isolated spleen cells. The result showed that PPCE exerted an immunostimulatory effect in vivo and in vitro. Specifically, PPCE significantly enhanced splenocyte proliferation and upregulated inflammatory cytokines (IL-2, IL-12, TNF-α, and IFN-γ) and NK cell activity in vitro. The immunostimulatory effect was further investigated through various immunological assays. Oral administration of PPCE increased the swimming time and number of immune cells in rats. Histological analysis revealed that PPCE administration exerted splenic recovery. Thus, P. oleracea L. based complex extracts may be used as an immunostimulatory agent in medicine or functional foods. [ABSTRACT FROM AUTHOR]

Published
2019
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6. Prolonged oral administration ofGastrodia elataextract improves spatial learning and memory of scopolamine-treated rats

Author

Park, Young-Mi, primary, Lee, Bong-Gun, additional, Park, Sang-Hoon, additional, Oh, Hong-Geun, additional, Kang, Yang-Gyu, additional, Kim, Ok-Jin, additional, Kwon, Lee-Seong, additional, Kim, Yong-Phill, additional, Choi, Min-Hyu, additional, Jeong, Yong-Seob, additional, Oh, Jisun, additional, and Lee, Hak-Yong, additional

Published
2015
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7. The Effects of Sea Cucumber as an Anti-gastritis, Anti-gastric Ulcer, and Anti-Helicobater

Author

Oh, Hong-Geun, primary, Moon, Dae-In, additional, Kim, Jung-Hoon, additional, Kang, Young-Rye, additional, Park, Jung-Woo, additional, Seo, Min-Young, additional, Park, Sang-Hoon, additional, Kang, Yang-Gyu, additional, Choe, Chung-Hyeon, additional, Park, In-Sun, additional, Kim, Ju, additional, Yu, Kang-Yeol, additional, Seol, Eu-Ddeum, additional, Kim, Ok-Jin, additional, and Lee, Hak-Yong, additional

Published
2012
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8. Prolonged oral administration of Gastrodia elataextract improves spatial learning and memory of scopolamine-treated rats

Author

Park, Young-Mi, Lee, Bong-Gun, Park, Sang-Hoon, Oh, Hong-Geun, Kang, Yang-Gyu, Kim, Ok-Jin, Kwon, Lee-Seong, Kim, Yong-Phill, Choi, Min-Hyu, Jeong, Yong-Seob, Oh, Jisun, and Lee, Hak-Yong

Abstract

Gastrodia elata(GE) is traditionally used for treatment of various disorders including neurodegenerative diseases such as Alzheimer’s disease. To investigate the neuroprotective effect of GE, amyloid-β peptide (Aβ)-treated PC12 cells were cultured with GE aqueous extract. In vitroassay demonstrated that 50 µM of pre-aggregated Aβ was lethal to about a half portion of PC12 cells and that Aβ aggregate-induced cell death was significantly decreased with GE treatment at ≤10 mg/mL in a dose-dependent manner. To further examine in vivocognitive-improving effects, an artificial amnesic animal model, scopolamineinjected Sprague-Dawley rats, were orally administered the extract for 6 weeks followed by behavioral tests (the passive avoidance test and Morris water maze test). The results showed that an acute treatment with scopolamine (1 mg/kg of body weight) effectively induced memory impairment in normal rats and that the learning and memory capability of scopolamine-treated rats improved after prolonged administration of GE extract (50, 250 and 500 mg/kg of body weight for 6 weeks). These findings suggest that a GE regimen may potentially ameliorate learning and memory deficits and/or cognitive impairments caused by neuronal cell death.

Published
2015
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