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1. Personality Type of the Glaucoma Patient

Author

Mitchell Watnik, Daniel Y. Kim, Isaac J. Barthelow, Ingrid J. Clark, James D. Brandt, Diana R. Shiba, Douglas E. Styles, and Michele C. Lim

Subjects
Male, medicine.medical_specialty, Personality Inventory, genetic structures, media_common.quotation_subject, Hysteria, Glaucoma, Minnesota Multiphasic Personality Inventory, Personality profile, Humans, Medicine, Personality, Prospective Studies, Psychiatry, Aged, media_common, business.industry, Automated perimetry, Middle Aged, medicine.disease, eye diseases, Hypochondriasis, Test (assessment), Ophthalmology, Personality type, Female, business, Attitude to Health, Glaucoma, Open-Angle
Abstract

To characterize the personality profile of glaucoma subjects.One hundred eight subjects including 56 open-angle glaucoma (OAG) and 52 controls were given the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) test and all performed automated perimetry. Clinical and demographic information which could relate to personality type was collected.OAG subjects had significantly higher Hypochondriasis (Hs; P=0.0082), Hysteria (Hy; P=0.0056), and Health Concerns (HEA; P=0.0025) mean scores than the control group. OAG subjects also had a significantly greater frequency of clinically abnormal score for hysteria (P=0.0262), and health concerns (P=0.0018). Multivariate analysis of variance revealed that Hypochondriasis, Hysteria, and Health Concerns scores were related to number of systemic medications used and to diagnostic group. Other potential explanatory variables such as sex, ethnicity, number of medical problems, length of glaucoma diagnosis, occurrence of glaucoma surgery, intraocular pressure, and visual status (logMAR, visual field indices) were not related to these personality scores.Patients with a diagnosis of OAG had more abnormal MMPI-2 scores in areas that focus upon concerns of somatic complaints and poor health. The use of systemic medications, which may be a constant reminder of illness, is a factor that may contribute to higher MMPI-2 scores.

Published
2007
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2. Asymmetries and Visual Field Summaries as Predictors of Glaucoma in the Ocular Hypertension Treatment Study

Author

Mary B. Hall, John M. Ramocki, Jody R. Piltz-Seymour, Donald F. Everett, Lea Morton, Robert A. Copeland, Stacey S. Goldstein, Michele C. Lim, Harry A. Quigley, Silvia Orengo-Nania, Bernard Becker, Heather Johnson, Richard K. Parrish, Manju Sharma, Teresa A. Long, Karen Clark, David S. Friedman, Cheryl L. Vitelli, Ditte J. Hess, Annisa L. Jamil, Michael A. Kass, Fermin P. Ballesteros, Lisa Levin, Fortunata Darmody, Carol J. Pollack-Rundle, Hina N. Ahmed, Celso Tello, Shan C. Lin, Maria Cristina Wells-Albornoz, Robb R. Shrader, Laura L. Schulz, Betsy Hornbeck, Ellen Long, Donald J. Zack, Jo Anne Katz, Nina C. Mondoc, Kathleen A. Lamping, Robert J. Derick, Julia A. Beiser, Felicia Keel, Kathryn R. Sherman, Allan J. Flach, John Connett, Alan L. Robin, Ronald L. Gross, Jeffrey M. Liebmann, Joern B. Soltau, Sandy Lear, Terry J. Bergstrom, Ramzi Hemady, Denise M. Owensby, William M. Bourne, Janice T. Petner, Arthur L. Schwartz, Shannan E. Bandermann, Ruth Vandenbroucke, Michelle A. Tehranisa, James D. Brandt, Linda M. Zangwill, Douglas R. Anderson, Valerie Margol, Charles J. Patorgis, Robert Ritch, Ingrid J. Clark, Allan E. Kolker, Osaro A. Okuonghae, John M. O'Grady, Joyce C. Schiffman, Y. P. Dang, Deborah Lee, Melanie Gutkowski, Robin L. Montgomery, Sayoko E. Moroi, Mark B. Sherwood, Rachel Scott, Simon K. Law, Deborah Darnley-Fisch, Mark S Juzych, Eydie Miller, Donald L. Budenz, Camilele M. Hylton, Keri Dirkes, N. Douglas Baker, Steven J. Gedde, Donald A. Abrams, Kimberly E. Cello, Deborah A. Dunn, Pamela M. Frady, Steven L. Mansberger, George A. Cioffi, Paul McManus, Deborah L. Simon, Bettina J. Modica, John L. Keltner, Emily L. Patterson, Myron Yanoff, Marianne L. Perry, Juanjuan Fan, Nancy J. Tvedt, Jean L. Walker, Shelly R. Smith, Kathyrne McKinney, Aldo Fantin, Dale K. Heur, Benita D. Slight, Karen D. Schacht, Francisco Fantes, Mark L. McDermott, Pamela A. Sample, Anjali M. Bhorade, Thomas S. Harbin, Carla J. Siegfried, Salvador Murillo, J. Philip Miller, Shaban Demirel, Marilyn A. Sponzo, Patricia A. Morris, Linda A. Van Conett, Eve J. Higginbotham, Barry R Davis, Michael V. Drake, Sheila M. Rock, Nauman R. Imami, Donna Leef, Madeline L. Del Calvo, Howard S. Weiss, J. Rigby Slight, Cheryl McGill, William J. Feuer, Anne L. Coleman, Dale K. Heuer, Juan Allen, David M. Lehmann, Edward M. Barnett, Clete Clark, Claude L Cowan, Jo Anne M Fraser, Irvin P. Pollack, Chris A. Johnson, Paul Weber, Mary Jameson, Jo Ann A Giaconi, Ivan R. Schwab, Sandra Quirin, David C. Herman, Montana L. Hooper, Judit Mohay, Steven M. Kymes, Bhupinder S. Dhillon, Julie M. Wright, Elizabeth Carnegie, Becky A. Nielsen, Ronald Munson, Monica Y. Allen, Teresa A. Roediger, M. Roy Wilson, G. Richard Bennett, Robert N. Weinreb, John A. Keltner, Allen D. Beck, Mary Bednarski, Henry D. Jampel, Christina A. Bruno, Bobbie Ballenberg, Kevin L. Powdrill, Anastasias Costarides, Anne M. Boeckl, Prithvi S. Sankar, Richard S. Baker, Robyn Priest-Reed, Douglas E. Gaasterland, Gregory L. Skuta, Lindsay C. Bennett, Jeffrey J. Casper, Frank S. Ashburn, Diane Moore, Nathan Congdon, Bret A Hughes, Mae E. Gordon, Robert L. Stamper, Douglas H. Johnson, and Richard A. Levine

Subjects
Male, Intraocular pressure, Time Factors, genetic structures, Open angle glaucoma, Eye disease, Vision Disorders, Ocular hypertension, Glaucoma, Article, Risk Factors, medicine, Psychophysics, Humans, Antihypertensive Agents, Intraocular Pressure, Monocular, business.industry, Middle Aged, Prognosis, medicine.disease, eye diseases, Visual field, Visual Field Tests, Optometry, Female, Ocular Hypertension, sense organs, Visual Fields, business, Glaucoma, Open-Angle
Abstract

To evaluate whether baseline visual field data and asymmetries between eyes predict the onset of primary open-angle glaucoma (POAG) in Ocular Hypertension Treatment Study (OHTS) participants.A new index, mean prognosis (MP), was designed for optimal combination of visual field thresholds, to discriminate between eyes that developed POAG from eyes that did not. Baseline intraocular pressure (IOP) in fellow eyes was used to construct measures of IOP asymmetry. Age-adjusted baseline thresholds were used to develop indicators of visual field asymmetry and summary measures of visual field defects. Marginal multivariate failure time models were constructed that relate the new index MP, IOP asymmetry, and visual field asymmetry to POAG onset for OHTS participants.The marginal multivariate failure time analysis showed that the MP index is significantly related to POAG onset (P0.0001) and appears to be a more highly significant predictor of POAG onset than either mean deviation (MD; P = 0.17) or pattern standard deviation (PSD; P = 0.046). A 1-mm Hg increase in IOP asymmetry between fellow eyes is associated with a 17% increase in risk for development of POAG. When threshold asymmetry between eyes existed, the eye with lower thresholds was at a 37% greater risk of development of POAG, and this feature was more predictive of POAG onset than the visual field index MD, though not as strong a predictor as PSD.The MP index, IOP asymmetry, and binocular test point asymmetry can assist in clinical evaluation of eyes at risk of development of POAG.

Published
2006
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