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The text is a review of the book "Prolegomena to a Science of Antiquity" by David Hernández de la Fuente. The author highlights the importance of studying Antiquity and reflects on the different historiographical and ideological trends that have worked in this area. The book is structured into six chapters and addresses topics such as the study of Antiquity in history, the birth of the sciences of Antiquity, and the expansion and specialization of these disciplines in the 19th century. The author also emphasizes the importance of philology in the study of Antiquity. The text analyzes the origin and development of archaeology and the study of material culture, which dates back to the travels of antiquarians in search of objects in historical places. The influence of archaeological excavations in Pompeii and Herculaneum during the reign of Charles III of Spain is mentioned. The text also addresses the crisis of European thought at the end of the 19th century and the impact of Friedrich Nietzsche and Sigmund Freud on studies of Antiquity. The text also examines new forms of studying Antiquity in the 20th century and current perspectives for its study, including the feminist movement and Black Lives Matter. The importance of the classical legacy is highlighted, and the disappearance of philology in universities is criticized. [Extracted from the article]

The text is a summary of the book "From the Archaeological Record to the Museum: The Path of History. Studies in Tribute to Mercedes Unzu Urmeneta," edited by Javier Martínez Sarasate, Javier Andreu Pintado, and María Jesús Peréx Agorreta. The book presents twenty-five contributions from experts in ancient and medieval history and archaeology of Navarra, addressing topics such as prehistory, the influence of Rome in the Ebro Valley and the Pyrenean region, and aspects of the medieval and modern era. It highlights the importance of Mercedes Unzu in the study of ancient Basques and her contribution to the knowledge of this society in Navarra. The chapters of the book deal with various topics related to the ancient city of Pompaelo and other archaeological findings in the region. The authors of the chapters include several experts in the field of archaeology and ancient and medieval history. [Extracted from the article]

The article "Preliminaries to a Science of Antiquity" is a review of the book written by David Hernández de la Fuente. The author highlights the importance of studying Antiquity and reflects on the different historiographic and ideological trends that have worked in this area. The book addresses topics such as the study of Antiquity in its beginnings, the birth of the Sciences of Antiquity, and the expansion and specialization of these disciplines in the 19th century. The importance of philology in the study of Antiquity and the difficulty of reconstructing the past due to separate copies of historical sources are also mentioned. The text analyzes the origin and development of archaeology and the study of material culture, as well as the influence of archaeological excavations in Pompeii and Herculaneum during the reign of Charles III of Spain. The crisis of European thought at the end of the 19th century and the importance of Friedrich Nietzsche and Sigmund Freud in studies on Antiquity are also addressed. The new forms of studying Antiquity in the 20th century and the influence of social movements such as feminism and Black Lives Matter on the understanding of Antiquity are mentioned. The importance of the classical legacy in Western society is highlighted, and the disappearance of philology in universities is criticized. [Extracted from the article]

Simple Summary: This study evaluates the occurrence of second primary neoplasms (SPNs) in individuals with a history of melanoma (MM) and identify factors that increase the risk in our population. A prospective cohort study was conducted, involving 529 MM survivors from January 2005 to August 2021. Among the 529 patients, 89 were diagnosed with SPNs, with 62 being skin tumors and 37 being solid organ tumors. The estimated probability of developing SPNs after MM diagnosis was found to increase over time, reaching 4.1% at 1 year, 11% at 5 years, and 19% at 10 years. Several factors were significantly associated with a higher risk of SPNs, including older age, primary MM location on the face or neck, and the histologic subtype of lentigo maligna MM. We conclude that individuals with primary MM located on the face and neck, as well as those with the histological subtype of lentigo maligna-MM, have a higher risk of developing SPNs. Age also independently influences the risk. Understanding these risk factors can assist in developing MM guidelines that provide specific follow-up recommendations for individuals at the highest risk. (1) Introduction: The association between melanoma (MM) and the occurrence of second primary neoplasms (SPNs) has been extensively studied, with reported incidence rates ranging from 1.5% to 20%. This study aims to evaluate the occurrence of SPNs in patients with a history of primary MM and to describe the factors that make the risk higher in our population. (2) Material and Methods: We conducted a prospective cohort study and calculated the incidence rates and relative risks (RR) for the development of different SPNs in 529 MM survivors from 1 January 2005 to 1 August 2021. Survival and mortality rates were obtained, and the Cox proportional hazards model was used to determine the demographic and MM-related factors that influence the overall risk. (3) Results: Among the 529 patients included, 89 were diagnosed with SPNs (29 prior to MM diagnosis, 11 synchronous, and 49 after MM), resulting in 62 skin tumors and 37 solid organ tumors. The estimated probability of developing SPNs after MM diagnosis was 4.1% at 1 year, 11% at 5 years, and 19% at 10 years. Older age, primary MM location on the face or neck, and histologic subtype of lentigo maligna mm were significantly associated with a higher risk of SPNs. (4) Conclusions: In our population, the risk of developing SPNs was higher in patients with primary MM located on the face and neck and with the histological subtype of lentigo maligna-MM. Age also independently influences the risk. Understanding these hazard factors can aid in the development of MM guidelines with specific follow-up recommendations for individuals with the highest risk. [ABSTRACT FROM AUTHOR]

This article discusses the successful treatment of epidermal nevus (EN) in a patient with phacomatosis spilosebacea (PSS) using topical sirolimus. EN is a type of birthmark, while PSS is a rare disorder characterized by the presence of EN along with other organ system involvement. Treatment of EN can be challenging, but topical sirolimus has shown promising results in managing difficult-to-treat dermatological disorders. In this case, a patient with PSS experienced a marked decrease in thickness of the EN lesions after 5 weeks of treatment with topical sirolimus, with no adverse effects reported. Further follow-up is needed to confirm the long-term improvement. [Extracted from the article]

The article summarizes María Engracia Muñoz-Santos' book on the spectacles in ancient Rome, focusing on the events that took place in the city of Rome. The author uses various sources to support her argument, including political, historical, epic texts, artistic and iconographic sources, as well as skeletal remains. The book examines different types of spectacles, such as gladiatorial battles, venationes, and damnationes, as well as chariot races in the circus. The origins of these events, the places where they took place, and the participants involved, including the editors, spectators, and other protagonists, are also mentioned. However, it is noted that the book does not provide enough information about the spectacles outside the city of Rome. [Extracted from the article]

Primary TMAU is a rare metabolic disorder that results from the failure of hepatic FMO3 to oxidize TMA due to a mutation in the I FMO3 i gene. Trimethylaminuria (TMAU) is a rare metabolic disorder characterized by an unpleasant body odor resembling decaying fish.[1] Biochemically, all affected patients present with an increased amount of trimethylamine (TMA) due to a mutation in the I FMO3 i gene, leading to the inability to oxidize this amine to the non-odorous metabolite, trimethylamine N-oxide (TMAO).[2] Patients with TMAU may experience serious psychosocial phenomena that limit their quality of life and also several systemic diseases.[3] Many therapeutic regimens have been proposed, and TMAU symptoms can be temporarily alleviated with certain drugs. Our patient exhibited a substantial and sustained improvement after a deprivation diet, underlining the importance of avoiding food containing elevated amounts of TMA in patients with mutations affecting the I FMO3 i gene. [Extracted from the article]