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1. Identification of prosaposin and transgelin as potential biomarkers for gallbladder cancer using quantitative proteomics.

Author

Sahasrabuddhe, Nandini A., Barbhuiya, Mustafa A., Bhunia, Shushruta, Subbannayya, Tejaswini, Gowda, Harsha, Advani, Jayshree, Shrivastav, Braj R., Navani, Sanjay, Leal, Pamela, Roa, Juan Carlos, Chaerkady, Raghothama, Gupta, Sanjeev, Chatterjee, Aditi, Pandey, Akhilesh, and Tiwari, Pramod K.

Subjects
*SAPOSINS, *MICROFILAMENT proteins, *BIOMARKERS, *GALLBLADDER cancer, *PROTEOMICS, *LYSOSOMES
Abstract

Highlights: [•] Quantitative proteomic analysis of gallbladder cancer. [•] LC–MS/MS analysis using Fourier transform high resolution mass spectrometry. [•] 2575 proteins identified including several upregulated lysosomal proteins. [•] Prosaposin and transgelin validated as candidate markers using tissue microarrays. [Copyright &y& Elsevier]

Published
2014
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