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Identification of prosaposin and transgelin as potential biomarkers for gallbladder cancer using quantitative proteomics.

Authors :
Sahasrabuddhe, Nandini A.
Barbhuiya, Mustafa A.
Bhunia, Shushruta
Subbannayya, Tejaswini
Gowda, Harsha
Advani, Jayshree
Shrivastav, Braj R.
Navani, Sanjay
Leal, Pamela
Roa, Juan Carlos
Chaerkady, Raghothama
Gupta, Sanjeev
Chatterjee, Aditi
Pandey, Akhilesh
Tiwari, Pramod K.
Source :
Biochemical & Biophysical Research Communications. Apr2014, Vol. 446 Issue 4, p863-869. 7p.
Publication Year :
2014

Abstract

Highlights: [•] Quantitative proteomic analysis of gallbladder cancer. [•] LC–MS/MS analysis using Fourier transform high resolution mass spectrometry. [•] 2575 proteins identified including several upregulated lysosomal proteins. [•] Prosaposin and transgelin validated as candidate markers using tissue microarrays. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
0006291X
Volume :
446
Issue :
4
Database :
Academic Search Index
Journal :
Biochemical & Biophysical Research Communications
Publication Type :
Academic Journal
Accession number :
95670676
Full Text :
https://doi.org/10.1016/j.bbrc.2014.03.017