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The P-block atom can effectively regulate the activity of two-electron CO2 reduction on Sn(200) surface.

Designing photocatalysts with suitable band alignment and considerable carrier mobility is extremely important. Here, by means of first-principles calculation, we systematically investigated the structural, photoelectronic, and carrier mobility behavior of the two-dimensional Janus MoSSe/WSSe superlattice. The results show that both armchair-type (A

Two-dimensional Janus MXY materials have been successfully synthesized from their parent species by CVD, SEAR, or PLD techniques. However, their detailed evolution process and underlying atomistic mechanism are far from understood conclusively, which are prompts for further research. Here, taking Janus MoSSe as a representation, the evolution process from MoS

Background: This study aimed to investigate the distribution and drug resistance of pathogens in hospitalized patients in the respiratory and critical care medicine department during the Coronavirus Disease 2019 (COVID-19) pandemic, analyze the risk factors of drug- resistance, and construct the risk prediction model.Methods: Patients who showed positive results in the bacterial culture in the Department of Respiratory and Critical Care Medicine of a large tertiary teaching hospital were enrolled using WHONET 5.6 software from December 2019 to June 2021. The patients were divided into training and validation sets based on a random number table method (8:2). A prediction model was then developed using the training set and verified using the validation set. Single factor analysis was used to compare the general situation and clinical characteristics of patients in the two groups. The risk prediction model of drug-resistant bacteria was constructed using the multi-factor logistic regression. A line diagram was then established based on the regression coefficient of the model. The model was internally and externally verified using receiver operating characteristic (ROC), area under the curve (AUC), and calibration curve.Results: Klebsiella pneumoniae (196/791, 24.78%), Pseudomonas aeruginosa (136/791, 17.19%), Acinetobacter baumannii (82/791, 10.37%), Escherichia coli (82/791, 10.37%), and Enterococcus faecalis (35/791, 4.42%) were the top five bacterial isolates. The isolated drug-resistant bacteria mainly included ESBL-producing E. coli (53/174, 30.46%) and K. pneumonia (28/174, 16.09%), carbapenem-resistant Acinetobacter baumannii (CR-Ab) (34/179, 19.54%), carbapenem-resistant Pseudomonas aeruginosa (CR-Pa) (17/174, 9.77%) and Klebsiella pneumoniae (CR-Kp) (7/174, 4.02%), and methicillin-resistant Staphylococcus aureus (MRSA) (11/174, 6.32%). gram-negative bacteria had a high resistance to ampicillin, ceftriaxone, cefotaxime, cefazolin, cefuroxime, aztreonam, cefepime, and ceftazidime. However, resistance rates of gram-negative bacteria to tigecycline, ertapenem, and cefoxitin were low. The nosocomial infection prediction model of drug-resistant bacteria was developed based on the combined use of antibiotics (antifungal drugs or respiratory quinolones), pharmacological immunosuppression, PCT > 0.5 ng/mL, CKD stage 4-5, indwelling catheter, and age > 60 years via multivariate logistic regression. The AUC under the ROC curve of the training and validation sets were 0.768 (95 % CI:0.624 - 0.817) and 0.753 (95 % CI: 0.657-0.785), respectively, indicating that the model had good discrimination. The predictive ability of the model was evaluated using calibration curve. The Hosmer-Lemeshow test showed that the model fitting had no significant difference (P > 0.05).Conclusions: E. coli, A. baumannii, K. pneumoniae, and P. aeruginosa are the main drug-resistant bacteria in nosocomial infection. COVID-19 does not increase the drug resistance pressure of the main strains. The combined use of antifungal, respiratory quinolone antibiotics, indwelling catheter, chronic renal failure, and age > 60 years are the independent risk factors of drug-resistant bacteria infection. The risk prediction model of drug-resistant bacteria infection can help in the prevention and control of hospital antibacterial-resistant bacteria infection.

The Schottky barrier height (ESBH) is a crucial factor in determining the transport properties of semiconductor materials and it directly regulates the carrier mobility in opto-electronics devices.

Background Shoulder function complications are common after treatment for breast cancer. Quite a few survivors still report a limited shoulder range of motion, even though the free range-of-motion upper limb exercise is helpful to restore shoulder function. Mirror therapy (MT) is a classical and effective rehabilitation technique to recover motor and sensory function for the limbs; in addition, studies have reported that MT has an influence on patients with shoulder functional dysfunction including increasing shoulder range of motion, improving shoulder function scores, and decreasing pain scores. Here, we describe a protocol of a randomized controlled trial to explore if free range-of-motion upper limb exercise based on MT has efficacy on shoulder function in survivors after surgery of breast cancer. Methods/design This is a prospective, single-blind, two-arm randomized controlled trial. An estimated 70 participants will be randomly allocated to (1) the MT group or (2) the control group. The participants in the control group receive free range-of-motion upper limb exercise, and participants in the MT group will engage in free range-of-motion upper limb exercise based on MT. The intervention will start on the first day after surgery and be completed at 8 weeks after surgery. The primary outcome in this protocol is shoulder range of motion (ROM), while the Constant-Murley Score (CMS); Disability of the Arm, Shoulder, and Hand Questionnaire (DASH); Tampa Scale of Kinesiophobia (13-item TSK); visual analog scale (VAS); grip strength; arm circumference; and lymphedema are the secondary outcomes. Assessment will be conducted before allocation (baseline) and at 2 weeks, 4 weeks, and 8 weeks after surgery. Discussion Based on the results that MT has an influence on shoulder function immediately after intervention in patients without nerve injury, this randomized controlled trial is to observe the efficacy of MT on shoulder function after a long-term intervention in breast cancer survivors. We look forward to the innovation of this study for both breast cancer rehabilitation and MT. Trial registration Chinese Clinical Trial Registry (ChiCTR) ChiCTR2000033080. Registered on 19 May 2020