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Your search keyword '"Roula Hourani"' showing total 6 results
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6 results on '"Roula Hourani"'

1. A multi-institutional meningioma MRI dataset for automated multi-sequence image segmentation

Author

Dominic LaBella, Omaditya Khanna, Shan McBurney-Lin, Ryan Mclean, Pierre Nedelec, Arif S. Rashid, Nourel hoda Tahon, Talissa Altes, Ujjwal Baid, Radhika Bhalerao, Yaseen Dhemesh, Scott Floyd, Devon Godfrey, Fathi Hilal, Anastasia Janas, Anahita Kazerooni, Collin Kent, John Kirkpatrick, Florian Kofler, Kevin Leu, Nazanin Maleki, Bjoern Menze, Maxence Pajot, Zachary J. Reitman, Jeffrey D. Rudie, Rachit Saluja, Yury Velichko, Chunhao Wang, Pranav I. Warman, Nico Sollmann, David Diffley, Khanak K. Nandolia, Daniel I Warren, Ali Hussain, John Pascal Fehringer, Yulia Bronstein, Lisa Deptula, Evan G. Stein, Mahsa Taherzadeh, Eduardo Portela de Oliveira, Aoife Haughey, Marinos Kontzialis, Luca Saba, Benjamin Turner, Melanie M. T. Brüßeler, Shehbaz Ansari, Athanasios Gkampenis, David Maximilian Weiss, Aya Mansour, Islam H. Shawali, Nikolay Yordanov, Joel M. Stein, Roula Hourani, Mohammed Yahya Moshebah, Ahmed Magdy Abouelatta, Tanvir Rizvi, Klara Willms, Dann C. Martin, Abdullah Okar, Gennaro D’Anna, Ahmed Taha, Yasaman Sharifi, Shahriar Faghani, Dominic Kite, Marco Pinho, Muhammad Ammar Haider, Michelle Alonso-Basanta, Javier Villanueva-Meyer, Andreas M. Rauschecker, Ayman Nada, Mariam Aboian, Adam Flanders, Spyridon Bakas, and Evan Calabrese

Subjects
Science
Abstract

Abstract Meningiomas are the most common primary intracranial tumors and can be associated with significant morbidity and mortality. Radiologists, neurosurgeons, neuro-oncologists, and radiation oncologists rely on brain MRI for diagnosis, treatment planning, and longitudinal treatment monitoring. However, automated, objective, and quantitative tools for non-invasive assessment of meningiomas on multi-sequence MR images are not available. Here we present the BraTS Pre-operative Meningioma Dataset, as the largest multi-institutional expert annotated multilabel meningioma multi-sequence MR image dataset to date. This dataset includes 1,141 multi-sequence MR images from six sites, each with four structural MRI sequences (T2-, T2/FLAIR-, pre-contrast T1-, and post-contrast T1-weighted) accompanied by expert manually refined segmentations of three distinct meningioma sub-compartments: enhancing tumor, non-enhancing tumor, and surrounding non-enhancing T2/FLAIR hyperintensity. Basic demographic data are provided including age at time of initial imaging, sex, and CNS WHO grade. The goal of releasing this dataset is to facilitate the development of automated computational methods for meningioma segmentation and expedite their incorporation into clinical practice, ultimately targeting improvement in the care of meningioma patients.

Published
2024
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2. Rheumatoid Cerebral Vasculitis in a Patient in Remission

Author

Georges El Hasbani, Hala El Ouweini, Fatema Dabdoub, Roula Hourani, Ali SM Jawad, and Imad Uthman

Subjects
Medicine (General), R5-920
Abstract

Cerebral vasculitis is a very rare extra-articular complication of rheumatoid arthritis (RA) that is often challenging to diagnose. Elevated titers of rheumatoid factor (RF), anti-cyclic citrullinated peptide antibodies (anti-CCP), and antinuclear antibodies (ANA) have been linked with severe complications. The absence of highly elevated titers of RF, anti-CCP, and ANA can complicate the diagnosis of RA-associated cerebral vasculitis. We report the case of a 59-year-old woman with long-standing arthritis maintained on rituximab and leflunomide who developed sudden headaches and altered level of consciousness. Laboratory work-up revealed normal lymphocyte count and mildly elevated total serum protein and anti-CCP with negative RF and ANA and no evidence for viral or bacterial infections. Cerebrospinal fluid analysis (CSF) showed slightly elevated anti-CCP with normal levels of CXCL-13 and interleukin 6 (IL-6). Brain magnetic resonance imaging (MRI) showed ill-defined lesion of high T2 signal. Using MR angiogram, MR perfusion, and MR spectroscopy, the diagnosis of rheumatoid cerebral vasculitis was confirmed. The patient was treated with intravenous methyl-prednisolone with fast complete improvement. We conclude that adequate immunosuppression in RA might not be able to prevent rare extra-articular manifestations such as rheumatoid cerebral vasculitis.

Published
2022
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4. Analysis of the BraTS 2023 Intracranial Meningioma Segmentation Challenge.

Author

Dominic LaBella, Ujjwal Baid, Omaditya Khanna, Shan McBurney-Lin, Ryan McLean, Pierre Nedelec, Arif Rashid, Nourel Hoda Tahon, Talissa Altes, Radhika Bhalerao, Yaseen Dhemesh, Devon Godfrey, Fathi Hilal, Scott Floyd, Anastasia Janas, Anahita Fathi Kazerooni, John Kirkpatrick, Collin Kent, Florian Kofler, Kevin Leu, Nazanin Maleki, Bjoern H. Menze, Maxence Pajot, Zachary J. Reitman, Jeffrey D. Rudie, Rachit Saluja, Yury Velichko, Chunhao Wang, Pranav Warman, Maruf Adewole, Jake Albrecht, Udunna Anazodo, Syed Muhammad Anwar, Timothy Bergquist, Sully F. Chen, Verena Chung, Gian Marco Conte, Farouk Dako, James A. Eddy, Ivan Ezhov, Nastaran Khalili, Juan Eugenio Iglesias, Zhifan Jiang, Elaine Johanson, Koen Van Leemput, Hongwei Bran Li, Marius George Linguraru, Xinyang Liu, Aria Mahtabfar, Zeke Meier, Ahmed W. Moawad, John Mongan, Marie Piraud, Russell Takeshi Shinohara, Walter F. Wiggins, Aly H. Abayazeed, Rachel Akinola, András Jakab, Michel Bilello, Maria Correia de Verdier, Priscila Crivellaro, Christos Davatzikos, Keyvan Farahani, John B. Freymann, Christopher Hess, Raymond Y. Huang, Philipp Lohmann, Mana Moassefi, Matthew W. Pease, Philipp Vollmuth, Nico Sollmann, David Diffley, Khanak K. Nandolia, Daniel I. Warren, Ali Hussain, Pascal Fehringer, Yulia Bronstein, Lisa Deptula, Evan G. Stein, Mahsa Taherzadeh, Eduardo Portela de Oliveira, Aoife Haughey, Marinos Kontzialis, Luca Saba, Benjamin Turner, Melanie M. T. Brüßeler, Shehbaz Ansari, Athanasios Gkampenis, David Maximilian Weiss, Aya Mansour, Islam H. Shawali, Nikolay Yordanov, Joel M. Stein, Roula Hourani, Mohammed Yahya Moshebah, Ahmed Magdy Abouelatta, Tanvir Rizvi, Klara Willms, Dann C. Martin, and Abdullah Okar

Published
2024
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5. Brain magnetic resonance imaging findings and brain volumetric differences in a large series of benign rolandic epilepsy

Author

Rida Salman, Wassim Nasreddine, Salem Hannoun, Widad Abou Chaar, Karl Asmar, Ahmad Beydoun, and Roula Hourani

Subjects
Case-Control Studies, Humans, Brain, Radiology, Nuclear Medicine and imaging, Neurology (clinical), General Medicine, Gray Matter, Child, Epilepsy, Rolandic, Magnetic Resonance Imaging
Abstract

Background Several studies with a small sample size have investigated the relationship between structural and functional changes on MRI and the clinical and natural history of BRE. We aim to assess the frequency of incidental epileptogenic lesions on brain MRI in a large cohort of patients diagnosed with BRE and to assess the difference in volumetric brain measurements in BRE patients compared to healthy controls. Methods The case–control study includes 214 typical BRE cases and 197 control children with non-epileptic spells. Brain MRIs were evaluated for abnormalities which were classified into normal and abnormal with or without epileptogenic lesions with categorization of epileptogenic lesions. Brain segmentation was also performed for a smaller group of BRE patients and another healthy control group. Pearson’s chi-squared test and two-tailed independent samples t-test were used. Results In patients with BRE, 7% had an epileptogenic lesion on their MRI. The frequency of epileptogenic lesion in the control group was 10.2% and not significantly different from those with BRE ( p= 0.2). Significantly higher intracranial and white matter volumes were found in BRE patients compared to the healthy group while lower gray matter volume was found in BRE patients. Cortical and subcortical regions showed either higher or lower volumes with BRE. Interestingly, altered subcallosal cortex development which has a known association with depression was also found in BRE. Conclusions Our findings confirm the absence of any association between specific brain MRI abnormalities and BRE. However, the altered cortical and subcortical development in BRE patients suggests a microstructural-functional correlation.

Published
2022
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6. Critical infections in the head and neck: A pictorial review of acute presentations and complications

Author

Muhammed Shareef, Youssef Ghosn, Mihran Khdhir, Tamara El Annan, Raquelle Alam, and Roula Hourani

Subjects
Radiology, Nuclear Medicine and imaging, Neurology (clinical), General Medicine
Abstract

Non-traumatic head and neck emergencies include several disease processes such as infectious, inflammatory, and malignant. Infections are among the most common pathological processes that affect the head and neck, and are particularly important due to their acute, severe, and potentially life-threatening nature. Radiologists need to be well acquainted with these entities because any delay or misdiagnosis can lead to significant morbidity and mortality. Having a general understanding of such diseases is crucial, their prevalence, clinical presentation, common causative pathogens, route of spread, potential complications, and multimodality radiological appearance. Furthermore, understanding the relevant anatomy of the region, including the various fascial planes and spaces, is essential for radiologists for accurate image interpretation and assessment of potential complications. Our aim is to review the most common severe infections affecting the head and neck as well as other rare but potentially life-threatening infections. We will also describe their imaging features while focusing on the anatomy of the regions involved and describing their potential complications and treatment options.

Published
2022

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