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Your search keyword '"Kowalski, Melanie"' showing total 9 results
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9 results on '"Kowalski, Melanie"'

3. Finding Balance : Collaborative Workflows for Risk Management in Sharing Cultural Heritage Collections Online

Author

Hintz, Carrie, author, Kowalski, Melanie T., author, Quigley, Sarah, author, and Bailey, Jody, author

Subjects
Social sciences, Library Science and Museum Studies, Textbooks
Abstract

Digitizing rare and unique historical documents so they can be shared online is mission-critical work for most cultural heritage institutions, but it can be difficult to complete this work, especially intellectual property rights management, at a scale that matches user demand. The authors of this open educational resource offer guidance for creating scalable, cross-functional workflows using a risk-management approach that increases efficiency and distributes responsibility for rights assessment work more equitably across stakeholders. It includes advice for navigating knowledge gaps, building an engaged team with the right skillsets, reimagining workflows, and rethinking traditional archival processing workflows to build capacity for rights analysis during arrangement and description. Each chapter includes a helpful exercise for implementing this guidance in your own institution.

Published
2023

4. Prognostic relevance of gait-related cognitive functions for dementia conversion in amnestic mild cognitive impairment.

Author

Tuena, Cosimo, Maestri, Sara, Serino, Silvia, Pedroli, Elisa, Stramba-Badiale, Marco, Riva, Giuseppe, the Alzheimer's Disease Neuroimaging Initiative, Silbert, Lisa C., Lind, Betty, Crissey, Rachel, Kaye, Jeffrey A., Carter, Raina, Dolen, Sara, Quinn, Joseph, Schneider, Lon S., Pawluczyk, Sonia, Becerra, Mauricio, Teodoro, Liberty, Dagerman, Karen, and Spann, Bryan M.

Subjects
MILD cognitive impairment, AMNESTIC mild cognitive impairment, DISEASE risk factors, EXECUTIVE function, COGNITIVE ability, COGNITIVE processing speed
Abstract

Background: Increasing research suggests that gait abnormalities can be a risk factor for Alzheimer's Disease (AD). Notably, there is growing evidence highlighting this risk factor in individuals with amnestic Mild Cognitive Impairment (aMCI), however further studies are needed. The aim of this study is to analyze cognitive tests results and brain-related measures over time in aMCI and examine how the presence of gait abnormalities (neurological or orthopedic) or normal gait affects these trends. Additionally, we sought to assess the significance of gait and gait-related measures as prognostic indicators for the progression from aMCI to AD dementia, comparing those who converted to AD with those who remained with a stable aMCI diagnosis during the follow-up. Methods: Four hundred two individuals with aMCI from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database were included. Robust linear mixed-effects models were used to study the impact of gait abnormalities on a comprehensive neuropsychological battery over 36 months while controlling for relevant medical variables at baseline. The impact of gait on brain measures was also investigated. Lastly, the Cox proportional-hazards model was used to explore the prognostic relevance of abnormal gait and neuropsychological associated tests. Results: While controlling for relevant covariates, we found that gait abnormalities led to a greater decline over time in attention (DSST) and global cognition (MMSE). Intriguingly, psychomotor speed (TMT-A) and divided attention (TMT-B) declined uniquely in the abnormal gait group. Conversely, specific AD global cognition tests (ADAS-13) and auditory-verbal memory (RAVLT immediate recall) declined over time independently of gait profile. All the other cognitive tests were not significantly affected by time or by gait profile. In addition, we found that ventricles size increased faster in the abnormal gait group compared to the normal gait group. In terms of prognosis, abnormal gait (HR = 1.7), MMSE (HR = 1.09), and DSST (HR = 1.03) covariates showed a higher impact on AD dementia conversion. Conclusions: The importance of the link between gait and related cognitive functions in terms of diagnosis, prognosis, and rehabilitation in aMCI is critical. We showed that in aMCI gait abnormalities lead to executive functions/attention deterioration and conversion to AD dementia. [ABSTRACT FROM AUTHOR]

Published
2023
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5. Reports Outline Alzheimer Disease Study Findings from University College London (UCL) (Association Between False Memories and Delusions in Alzheimer Disease).

Subjects
CENTRAL nervous system diseases, ALZHEIMER'S disease, BRAIN diseases, MEDICAL societies, FALSE memory syndrome, DELUSIONS
Abstract

A recent study conducted by researchers at University College London (UCL) explored the association between false memories and delusions in Alzheimer's disease (AD). The study aimed to understand the mechanisms behind delusion formation in AD and whether delusions are linked to false recognition and lower brain volumes. The researchers analyzed data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) and found that false memories were not directly associated with the presence of delusions. Additionally, there was no overlap between brain regions associated with false memories and those associated with delusions. These findings suggest that delusions in AD do not arise from misremembering and support the search for specific therapeutic targets for psychosis treatment. [Extracted from the article]

Published
2024

6. University of Washington Researcher Updates Understanding of Alzheimer Disease (Interpretable discriminant analysis for functional data supported on random nonlinear domains with an application to Alzheimer's disease).

Subjects
ALZHEIMER'S disease, DISCRIMINANT analysis, CENTRAL nervous system diseases, RESEARCH personnel, FUNCTIONAL analysis
Abstract

A recent report discusses new research on Alzheimer's disease conducted by a researcher at the University of Washington. The study introduces a novel framework for classifying functional data related to Alzheimer's disease based on cortical surface geometry and cortical thickness. The proposed model uses a direct approach to estimate the most discriminant direction while controlling for complexity. The research applies this method to a pooled dataset from the Alzheimer's Disease Neuroimaging Initiative and Parkinson's Progression Markers Initiative, identifying discriminant directions consistent with existing neuroscience literature. The full article can be accessed for free through the provided link. This article discusses a study conducted at the University of Washington in Seattle, United States, focusing on dementia and tauopathies. Tauopathies are a group of neurodegenerative diseases that include Alzheimer's disease. The study aims to understand the underlying mechanisms of these conditions and develop potential treatments. The research provides valuable insights into brain diseases and conditions, specifically those affecting the central nervous system. [Extracted from the article]

Published
2024

7. Choisir sans préférer : dépasser le paradigme libéral pour repenser le multiculturalisme et les femmes

Author

Anne Iavarone-Turcotte and Anne Iavarone-Turcotte

Abstract

Ce livre montre que l'on peut repenser le rapport tendu entre multiculturalisme et féminisme, d'une manière qui dépasse les automatismes que dicte la doctrine libérale classique. En philosophie comme en droit, ces automatismes sont logés dans le paradigme du choix, qui offre des réponses simples – presque intuitives – à la question. Car les femmes concernées ne choisissent-elles pas les pratiques pointées du doigt, de même que leur communauté d'appartenance? Ne sont-elles pas libres de quitter cette communauté, ou d'y rester, mais de réformer – ensemble – ses pratiques? Ne faut-il pas reconnaître et respecter ces choix individuels et collectifs, sous peine d'inviter le paternalisme et la victimisation? À ces questions, certaines féministes répondent que l'on peut « choisir sans préférer », même de manière libre et éclairée. Cette intuition suggère des pistes encore inédites en droit, qui sont explorées ici au moyen de l'exemple fécond du règlement religieux des divorces.

Published
2024

8. Reports Outline Alzheimer Disease Study Findings from University College London (UCL) (Association Between False Memories and Delusions in Alzheimer Disease)

Subjects
Research, Reports, Diseases -- Research -- United Kingdom, Medical research -- Reports, Alzheimer's disease -- Research, Medicine, Experimental -- Reports
Abstract

2024 OCT 4 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- New study results on Alzheimer disease have been published. According to news reporting [...]

Published
2024

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