32 results on '"Kihara, Yasuki"'
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2. Relationship between 2nd-generation angiotensin receptor blockers and the risk of hypotension in COVID-19 patients admitted to hospital
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Yoshihara, Fumiki, Matsuzawa, Yasushi, Nakatsuka, Kiyomasa, Kirigaya, Jin, Takeuchi, Ichiro, Kimura, Kazuo, Konishi, Masaaki, Tamura, Kouichi, Fukui, Kazuki, Tsukahara, Kengo, Shimizu, Hiroyuki, Iwabuchi, Keisuke, Yamada, Yu, Saka, Kenichiro, Sato, Yukihito, Ogawa, Masahiro, Hayakawa, Kayoko, Ohmagari, Norio, Ikeda, Syuhei, Akao, Masaharu, Shimomura, Hideki, Kihara, Yasuki, Yoshimoto, Akihiro, Morita, Masanori, Kumada, Norihiko, Ogata, Soshiro, Nishimura, Kunihiro, Arisato, Tetsuya, Matsuo, Miki, Kishida, Masatsugu, Yasuda, Satoshi, and Ogawa, Hisao
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- 2024
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3. Clinical outcomes of COVID-19 caused by the Alpha variant compared with one by wild type in Kobe, Japan. A multi-center nested case-control study
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Doi, Asako, Iwata, Kentaro, Nakamura, Tadahiro, Oh, Koji, Isome, Kenichi, Hasegawa, Kohei, Kuroda, Hirokazu, Hasuike, Toshikazu, Seo, Ryutaro, Kosai, Hisato, Nakanishi, Noriko, Nomoto, Ryohei, Fujiyama, Riyo, Kusunoki, Nobuya, Iwamoto, Tomotada, Nishioka, Hiroaki, Tomii, Keisuke, and Kihara, Yasuki
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- 2023
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4. GJA1 gene polymorphism is a genetic predictor of recurrence after pulmonary vein isolation in patients with paroxysmal atrial fibrillation
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Okamura, Sho, Ochi, Hidenori, Onohara, Yuko, Nakashima, Mika, Akiyama, Rie, Tokuyama, Takehito, Okubo, Yousaku, Ikeuchi, Yoshihiro, Miyauchi, Shunsuke, Miyamoto, Shogo, Oguri, Naoto, Uotani, Yukimi, Odake, Yodo, Chayama, Kazuaki, Kihara, Yasuki, and Nakano, Yukiko
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- 2022
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5. Modifiers of the Risk of Diabetes for Long-Term Outcomes After Coronary Revascularization: CREDO-Kyoto PCI/CABG Registry
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Kimura, Takeshi, Shiomi, Hiroki, Matsuda, Mitsuo, Takeuchi, Yuzo, Mitsuoka, Hirokazu, Uegaito, Takashi, Nakagawa, Yoshihisa, Tamura, Toshihiro, Konishi, Takashi, Ootani, Seiji, Fujiwara, Hisayoshi, Takatsu, Yoshiki, Sato, Yukihito, Taniguchi, Ryoji, Kataoka, Kazuaki, Inoko, Moriaki, Nohara, Ryuji, Nakano, Kimisato, Miyamoto, Syoichi, Kunihiko, Nagai, Murakami, Tomoyuki, Takeda, Teruki, Ishida, Katsuya, Nobuyoshi, Masakiyo, Yamaji, Kyohei, Yasumoto, Hitoshi, Iwabuchi, Masashi, Ando, Kenji, Domei, Takenori, Kato, Masayuki, Tatami, Ryozo, Shirotani, Manabu, Hattori, Ryuichi, Kita, Toru, Furukawa, Yutaka, Ehara, Natsuhiko, Kihara, Yasuki, Eizawa, Hiroshi, Kato, Hiroshi, Ishii, Katsuhisa, Aoyama, Takeshi, Sakurai, Takahiro, Kawanami, Masaki, Suyama, Tamaki, Tada, Eiji, Tanaka, Masaru, Inada, Tsukasa, Uzui, Hiroyasu, Nakano, Akira, Lee, Jong-Dae, Onodera, Tomoya, Takizawa, Akinori, Ryuzo, Nawada, Shinoda, Eiji, Takahashi, Masaaki, Yamada, Miho, Horie, Minoru, Yamamoto, Takashi, Takashima, Hiroyuki, Sakai, Hiroshi, Tamura, Takashi, Toyofuku, Mamoru, Kotoura, Hajime, Miura, Akira, Takahashi, Mamoru, Matoba, Yoshiki, Takumi, Takuro, Tei, Chuwa, Hamasaki, Shuichi, Doi, Osamu, Kambara, Hirofumi, Kaburagi, Satoshi, Sakamoto, Hiroki, Tada, Tomohisa, Mitsudo, Kazuaki, Kadota, Kazushige, Tada, Takeshi, Miki, Shinji, Mizoguchi, Tetsu, Akira, Yoshida, Kaneda, Kazuhisa, Ogawa, Hisao, Sugamura, Koichi, Sugiyama, Seigo, Doyama, Kiyoshi, Araki, Makoto, Suwa, Satoru, Sakata, Ryuzo, Ikeda, Tadashi, Marui, Akira, Minatoya, Kenji, Yamazaki, Kazuhiro, Onoe, Masahiko, Ogawa, Tatsuya, Yamanaka, Kazuo, Iwakura, Atsushi, Ohno, Nobuhisa, Fujiwara, Keiichi, Hanyu, Michiya, Soga, Kinji, Matsushita, Tsutomu, Nishiwaki, Noboru, Yoshida, Yuichi, Tamura, Nobushige, Okada, Yukikatsu, Nasu, Michihiro, Koyama, Tadaaki, Nakayama, Shogo, Tanaka, Kuniyoshi, Koshiji, Takaaki, Morioka, Koichi, Shimamoto, Mitsuomi, Yamazaki, Fumio, Terai, Yasuhiko, Nishizawa, Junichiro, Aota, Masaki, Kanemitsu, Naoki, Hara, Hiroyuki, Tabata, Takafumi, Imoto, Yutaka, Yamamoto, Hiroyuki, Matsuda, Katsuhiko, Nara, Masafumi, Tsuneyoshi, Hiroshi, Komiya, Tatsuhiko, Nakajima, Hiroyuki, Esaki, Jiro, Kawasuji, Michio, Moriyama, Syuji, Tambara, Keiichi, Arimura, Sakiko, Fujino, Yumika, Hanazawa, Miya, Hibi, Chikako, Kato, Risa, Kinoshita, Yui, Kitagawa, Kumiko, Kitamura, Masayo, Kuwahara, Takahiro, Sachiko, Maeda, Miki, Izumi, Minematsu, Saeko, Nishida, Satoko, Okamoto, Naoko, Saeki, Asuka, Sasae, Hitomi, Sato, Yuki, Takahashi, Asuka, Takinami, Emi, Tezuka, Saori, Tsuda, Marina, Tsumori, Miyuki, Uchida, Yuriko, Yamamoto, Yuko, Yamauchi, Misato, Yamazaki, Itsuki, Yoshimoto, Mai, Abe, Mitsuru, Fuki, Masayuki, Hayano, Mamoru, Kato, Eri, Kato, Yoshihiro, Matsumura-Nakano, Yukiko, Nakajima, Tetsu, Nakatsuma, Kenji, Natsuaki, Masahiro, Takeji, Yasuaki, Tazaki, Junichi, Tokushige, Akihiro, Watanabe, Hiroki, Yaku, Hidenori, Yamamoto, Erika, Yamamoto, Ko, Yamashita, Yugo, Yoshikawa, Yusuke, Morimoto, Takeshi, Kato, Eri T., Imada, Kazuaki, Nishikawa, Ryusuke, Mabuchi, Hiroshi, and Soga, Yoshiharu
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- 2022
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6. Current conditions and significance of outpatient cardiac rehabilitation and home nursing-care services in heart failure patients with mid-range or preserved ejection fraction: post-hoc analysis of the REAL-HF registry
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Kitagawa, Toshiro, Hidaka, Takayuki, Watanabe, Noriaki, Naka, Makiko, Yamaguchi, Mizuho, Kanai, Kana, Isobe, Mitsuaki, Kihara, Yasuki, and Nakano, Yukiko
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- 2022
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7. JCS/JHFS 2021 Guideline Focused Update on Diagnosis and Treatment of Acute and Chronic Heart Failure
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Tsutsui, Hiroyuki, Ide, Tomomi, Ito, Hiroshi, Kihara, Yasuki, Kinugawa, Koichiro, Kinugawa, Shintaro, Makaya, Miyuki, Murohara, Toyoaki, Node, Koichi, Saito, Yoshihiko, Sakata, Yasushi, Shimizu, Wataru, Yamamoto, Kazuhiro, Bando, Yasuko, Iwasaki, Yu-Ki, Kinugasa, Yoshiharu, Mizote, Isamu, Nakagawa, Hitoshi, Oishi, Shogo, Okada, Akiko, Tanaka, Atsushi, Akasaka, Takashi, Ono, Minoru, Kimura, Takeshi, Kohsaka, Shun, Kosuge, Masami, and Momomura, Shin-Ichi
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- 2021
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8. Risk stratification and prognosis prediction using cardiac biomarkers in COVID-19: a single-centre retrospective cohort study
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Sano, Madoka, primary, Toyota, Toshiaki, additional, Morimoto, Takeshi, additional, Noguchi, Yu, additional, Shigeno, Ryo, additional, Murai, Ryosuke, additional, Okada, Taiji, additional, Sasaki, Yasuhiro, additional, Taniguchi, Tomohiko, additional, Kim, Kitae, additional, Kobori, Atsushi, additional, Ehara, Natsuhiko, additional, Kinoshita, Makoto, additional, Doi, Asako, additional, Tomii, Keisuke, additional, Kihara, Yasuki, additional, and Furukawa, Yutaka, additional
- Published
- 2024
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9. Risk of Death and Cardiovascular Events in Asian Patients With Atrial Fibrillation and Chronic Obstructive Pulmonary Disease: A Report From the Prospective APHRS Registry
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Bucci, Tommaso, primary, Romiti, Giulio Francesco, additional, Shantsila, Alena, additional, Teo, Wee‐Siong, additional, Park, Hyung‐Wook, additional, Shimizu, Wataru, additional, Corica, Bernadette, additional, Proietti, Marco, additional, Tse, Hung‐Fat, additional, Chao, Tze‐Fan, additional, Frost, Frederick, additional, Lip, Gregory Y. H., additional, David, Chun‐Wah Siu, additional, Yodogawa, Kenji, additional, Tsutsui, Hiroyuki, additional, Mukai, Yasushi, additional, Tomita, Hirofumi, additional, Horiuchi, Daisuke, additional, Hagii, Joji, additional, Aonuma, Kazutaka, additional, Okumura, Yasuo, additional, Goya, Masahiko, additional, Hirao, Kenzo, additional, Hagiwara, Nobuhisa, additional, Suzuki, Atsushi, additional, Yamane, Teiichi, additional, Ikeda, Takanori, additional, Yuzawa, Hitomi, additional, Satomi, Kazuhiro, additional, Yazaki, Yoshinao, additional, Fukuda, Keiichi, additional, Kobayashi, Yoshinori, additional, Morita, Norishige, additional, Murohara, Toyoaki, additional, Watanabe, Eiichi, additional, Harada, Masahide, additional, Sakagami, Satoru, additional, Saeki, Takahiro, additional, Kusano, Kengo, additional, Miyamoto, Koji, additional, Miyazaki, Shinsuke, additional, Tada, Hiroshi, additional, Inoue, Koichi, additional, Tanaka, Nobuaki, additional, Koretsune, Yukihiro, additional, Abe, Haruhiko, additional, Kihara, Yasuki, additional, Nakano, Yukiko, additional, Shimizu, Akihiko, additional, Yoshiga, Yasuhiro, additional, Sakamoto, Tomohiro, additional, Okumura, Ken, additional, Takahashi, Naohiko, additional, Shinohara, Tetsuji, additional, Soejima, Kyoko, additional, Takagi, Masahiko, additional, Kawamura, Mitsuharu, additional, Munetsugu, Yumi, additional, Kim, Sung‐Hwan, additional, Shim, Jae‐Min, additional, Uhm, Jae Sun, additional, Im, Sung Il, additional, Par, Hyoung‐Seob, additional, Kim, Jun Hyung, additional, On, Young Keun, additional, Oh, Il‐Young, additional, Shin, Seung Yong, additional, Ko, Jum Suk, additional, Park, Jun Beom, additional, Wong, Kelvin Cheok‐Keng, additional, Lim, Toon‐Wei, additional, Foo, David, additional, Chen, Shih‐Ann, additional, Lin, YennJiang, additional, Chung, Fa‐Po, additional, Hu, Yu‐Feng, additional, Chang, Shil‐Lin, additional, Tuan, Ta‐Chuan, additional, Liao, Jo‐Nan, additional, Li, Cheng‐Hung, additional, Huang, Jin‐Long, additional, Hsieh, Yu‐Cheng, additional, Wu, Tsu‐Juey, additional, Liao, Ying‐Chieh, additional, Chiang, Cheng‐Hung, additional, Hsiao, Hsiang‐Chiang, additional, Yeh, Tung‐Chen, additional, Lin, Wei‐Siang, additional, Lin, Wen‐Yu, additional, Kuo, Jen‐Yuan, additional, Hong, Chong‐Lie, additional, Wu, Yih‐Je, additional, Li, Ying‐Siang, additional, Tsai, Jui‐Peng, additional, Sung, Kuo‐Tzu, additional, and Chang, Sheng‐Hsiung, additional
- Published
- 2024
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10. The International Classification of Functioning, Disabilities, and Health categories rated as necessary for care planning for older patients with heart failure: a survey of care managers in Japan
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Shiota, Shigehito, Kitagawa, Toshiro, Hidaka, Takayuki, Goto, Naoya, Mio, Naoki, Kanai, Kana, Naka, Makiko, Togino, Hiroko, Mochizuki, Mariko, Ochikubo, Hiroyuki, Nakano, Yukiko, Kihara, Yasuki, and Kimura, Hiroaki
- Published
- 2021
- Full Text
- View/download PDF
11. Smoking status and endothelial function in Japanese men
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Hashimoto, Haruki, Maruhashi, Tatsuya, Yamaji, Takayuki, Harada, Takahiro, Han, Yiming, Takaeko, Yuji, Kihara, Yasuki, Chayama, Kazuaki, Goto, Chikara, Aibara, Yoshiki, Yusoff, Farina Mohamad, Kishimoto, Shinji, Kajikawa, Masato, Nakashima, Ayumu, and Higashi, Yukihito
- Published
- 2021
- Full Text
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12. Minor allele of GJA1 gene polymorphism is associated with higher heart rate during atrial fibrillation
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Okamura, Sho, Onohara, Yuko, Ochi, Hidenori, Tokuyama, Takehito, Hironobe, Naoya, Okubo, Yosaku, Ikeuchi, Yoshihiro, Miyauchi, Shunsuke, Chayama, Kazuaki, Kihara, Yasuki, and Nakano, Yukiko
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- 2021
- Full Text
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13. A cross-sectional follow up study to estimate seroprevalence of coronavirus disease 2019 in Kobe, Japan
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Doi, Asako, Iwata, Kentaro, Kuroda, Hirokazu, Hasuike, Toshikazu, Nasu, Seiko, Nishioka, Hiroaki, Tomii, Keisuke, Morimoto, Takeshi, and Kihara, Yasuki
- Published
- 2021
- Full Text
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14. Serum Values of Cholesterol Absorption and Synthesis Biomarkers in Japanese Healthy Subjects: The CACHE Study HEALTHY Analysis
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Ishibashi, Yutaka, primary, Yoshida, Hiroshi, additional, Kotani, Kazuhiko, additional, Akiyama, Yusuke, additional, Fujii, Hisako, additional, Harada-Shiba, Mariko, additional, Ishida, Tatsuro, additional, Ishigaki, Yasushi, additional, Kabata, Daijiro, additional, Kihara, Yasuki, additional, Kurisu, Satoshi, additional, Masuda, Daisaku, additional, Matoba, Tetsuya, additional, Matsuki, Kota, additional, Matsumura, Takeshi, additional, Mori, Kenta, additional, Nakagami, Tomoko, additional, Nakazato, Masamitsu, additional, Taniuchi, Satsuki, additional, Ueno, Hiroaki, additional, Yamashita, Shizuya, additional, Yano, Shozo, additional, Yoshida, Hisako, additional, and Shoji, Tetsuo, additional
- Published
- 2023
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15. Association between Familial Hypercholesterolemia and Serum Levels of Cholesterol Synthesis and Absorption Markers: The CACHE Study FH Analysis
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Matsuki, Kota, primary, Harada-Shiba, Mariko, additional, Hori, Mika, additional, Ogura, Masatsune, additional, Akiyama, Yusuke, additional, Fujii, Hisako, additional, Ishibashi, Yutaka, additional, Ishida, Tatsuro, additional, Ishigaki, Yasushi, additional, Kabata, Daijiro, additional, Kihara, Yasuki, additional, Kotani, Kazuhiko, additional, Kurisu, Satoshi, additional, Masuda, Daisaku, additional, Matoba, Tetsuya, additional, Matsumura, Takeshi, additional, Mori, Kenta, additional, Nakagami, Tomoko, additional, Nakazato, Masamitsu, additional, Taniuchi, Satsuki, additional, Ueno, Hiroaki, additional, Yamashita, Shizuya, additional, Yoshida, Hiroshi, additional, Yoshida, Hisako, additional, and Shoji, Tetsuo, additional
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- 2023
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16. A COMBINED APPROACH USING HIGH-SENSITIVE TROPONIN I AND N-TERMINAL PRO-B-TYPE NATRIURETIC PEPTIDE FOR RISK STRATIFICATION IN PATIENTS WITH CORONAVIRUS DISEASE 2019
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Sano, Madoka, primary, Toyota, Toshiaki, additional, Morimoto, Takeshi, additional, Murai, Ryosuke, additional, Okada, Taiji, additional, Taniguchi, Tomohiko, additional, Kim, Kitae, additional, Kobori, Atsushi, additional, Ehara, Natsuhiko, additional, Kinoshita, Makoto, additional, Doi, Asako, additional, Tomii, Keisuke, additional, Kihara, Yasuki, additional, and Furukawa, Yutaka, additional
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- 2023
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17. Association of Serum Levels of Cholesterol Absorption and Synthesis Markers with the Presence of Cardiovascular Disease: The CACHE Study CVD Analysis
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Katsuki, Shunsuke, primary, Matoba, Tetsuya, additional, Akiyama, Yusuke, additional, Yoshida, Hiroshi, additional, Kotani, Kazuhiko, additional, Fujii, Hisako, additional, Harada-Shiba, Mariko, additional, Ishibashi, Yutaka, additional, Ishida, Tatsuro, additional, Ishigaki, Yasushi, additional, Kabata, Daijiro, additional, Kihara, Yasuki, additional, Kurisu, Satoshi, additional, Masuda, Daisaku, additional, Matsuki, Kota, additional, Matsumura, Takeshi, additional, Mori, Kenta, additional, Nakagami, Tomoko, additional, Nakazato, Masamitsu, additional, Taniuchi, Satsuki, additional, Ueno, Hiroaki, additional, Yamashita, Shizuya, additional, Yoshida, Hisako, additional, Tsutsui, Hiroyuki, additional, and Shoji, Tetsuo, additional
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- 2023
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18. Targeted deep sequencing analyses of long QT syndrome in a Japanese population
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Nagata, Yuki, primary, Watanabe, Ryo, additional, Eichhorn, Christian, additional, Ohno, Seiko, additional, Aiba, Takeshi, additional, Ishikawa, Taisuke, additional, Nakano, Yukiko, additional, Aizawa, Yoshiyasu, additional, Hayashi, Kenshi, additional, Murakoshi, Nobuyuki, additional, Nakajima, Tadashi, additional, Yagihara, Nobue, additional, Mishima, Hiroyuki, additional, Sudo, Takeaki, additional, Higuchi, Chihiro, additional, Takahashi, Atsushi, additional, Sekine, Akihiro, additional, Makiyama, Takeru, additional, Tanaka, Yoshihiro, additional, Watanabe, Atsuyuki, additional, Tachibana, Motomi, additional, Morita, Hiroshi, additional, Yoshiura, Koh-ichiro, additional, Tsunoda, Tatsuhiko, additional, Watanabe, Hiroshi, additional, Kurabayashi, Masahiko, additional, Nogami, Akihiko, additional, Kihara, Yasuki, additional, Horie, Minoru, additional, Shimizu, Wataru, additional, Makita, Naomasa, additional, and Tanaka, Toshihiro, additional
- Published
- 2022
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19. Association of Kidney Function with Serum Levels of Cholesterol Absorption and Synthesis Markers: The CACHE Study CKD Analysis
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Shoji, Tetsuo, primary, Akiyama, Yusuke, additional, Fujii, Hisako, additional, Harada-Shiba, Mariko, additional, Ishibashi, Yutaka, additional, Ishida, Tatsuro, additional, Ishigaki, Yasushi, additional, Kabata, Daijiro, additional, Kihara, Yasuki, additional, Kotani, Kazuhiko, additional, Kurisu, Satoshi, additional, Masuda, Daisaku, additional, Matoba, Tetsuya, additional, Matsuki, Kota, additional, Matsumura, Takeshi, additional, Mori, Kenta, additional, Nakagami, Tomoko, additional, Nakazato, Masamitsu, additional, Taniuchi, Satsuki, additional, Ueno, Hiroaki, additional, Yamashita, Shizuya, additional, Yoshida, Hisako, additional, and Yoshida, Hiroshi, additional
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- 2022
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20. Features and Outcomes of Histologically Proven Myocarditis With Fulminant Presentation
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Kanaoka, Koshiro, primary, Onoue, Kenji, additional, Terasaki, Satoshi, additional, Nakano, Tomoya, additional, Nakai, Michikazu, additional, Sumita, Yoko, additional, Hatakeyama, Kinta, additional, Terasaki, Fumio, additional, Kawakami, Rika, additional, Iwanaga, Yoshitaka, additional, Miyamoto, Yoshihiro, additional, Saito, Yoshihiko, additional, Yuda, Satoshi, additional, Tanno, Masaya, additional, Takahashi, Toru, additional, Yokoshiki, Hisashi, additional, Toba, Masahiro, additional, Anzai, Toshihisa, additional, Nagai, Toshiyuki, additional, Sato, Takuma, additional, Takenaka, Takashi, additional, Yamazaki, Seiji, additional, Katagiri, Yuki, additional, Takeuchi, Toshiharu, additional, Sugitatsu, Kazuya, additional, Kakinoki, Shigeo, additional, Matsumoto, Tomoaki, additional, Urasawa, Kazushi, additional, Tan, Michinao, additional, Tsujino, Ichizo, additional, Kamigaki, Mitsunori, additional, Tomita, Hirofumi, additional, Hanada, Kenji, additional, Kushibiki, Motoi, additional, Nakamura, Akihiro, additional, Morino, Yoshihiro, additional, Nasu, Takahito, additional, Yasuda, Satoshi, additional, Suzuki, Hideaki, additional, Iwabuchi, Kaoru, additional, Tsuji, Kanako, additional, Namiuchi, Shigeto, additional, Komaru, Tatsuya, additional, Yagi, Masahiro, additional, Uematsu, Shoko, additional, Takahashi, Toshiaki, additional, Takeda, Satoru, additional, Nakanishi, Toru, additional, Watanabe, Masafumi, additional, Wanezaki, Masahiro, additional, Matsui, Motoyuki, additional, Sugawara, Shigeo, additional, Takeishi, Yasuchika, additional, Oikawa, Masayoshi, additional, Komatsu, Nobuo, additional, Suzuki, Satoshi, additional, Okamoto, Hiroshi, additional, Takeyasu, Noriyuki, additional, Akiyama, Daiki, additional, Eki, Yutaka, additional, Kakuta, Tsunekazu, additional, Sugiyama, Tomoyo, additional, Koizumi, Tomomi, additional, Ueno, Koji, additional, Kario, Kazuomi, additional, Taki, Mizuri, additional, Matsumoto, Yuri, additional, Yasu, Takanori, additional, Nishioka, Osamu, additional, Naito, Shigeto, additional, Murata, Makoto, additional, Tange, Shoichi, additional, Kaneko, Katsumi, additional, Muto, Makoto, additional, Inagaki, Hiroshi, additional, Hasegawa, Shuichi, additional, Tachibana, Eizo, additional, Atsumi, Wataru, additional, Suzuki, Masahiro, additional, Muramatsu, Toshihiro, additional, Yamada, Yoshihiro, additional, Taguchi, Isao, additional, Fukuda, Yoshiaki, additional, Matsui, Akihiro, additional, Kanda, Junji, additional, Hozawa, Koji, additional, Matsumura, Akihiko, additional, Shimizu, Wataru, additional, Yamamoto, Takeshi, additional, Komuro, Issei, additional, Hatano, Masaru, additional, Ikeda, Takanori, additional, Kiuchi, Shunsuke, additional, Chikamori, Taishiro, additional, Takei, Yasuyoshi, additional, Soejima, Kyoko, additional, Minamishima, Toshinori, additional, Tanaka, Hiroyuki, additional, Shimizu, Shigeo, additional, Kasao, Masashi, additional, Kadohira, Tadayuki, additional, Minamino, Tohru, additional, Shimada, Kazunori, additional, Iwata, Hiroshi, additional, Momiyama, Yukihiko, additional, Ashikaga, Takashi, additional, Nozato, Toshihiro, additional, Fujiwara, Yasumasa, additional, Inoue, Kenji, additional, Sasano, Tetsuo, additional, Matsuda, Junji, additional, Ishii, Yasuhiro, additional, Ono, Yuichi, additional, Tanabe, Kengo, additional, Horiuchi, Yu, additional, Shinke, Toshiro, additional, Kodama, Yusuke, additional, Moroi, Masao, additional, Yazaki, Yoshiyuki, additional, Mizumura, Taisuke, additional, Ohta, Hiroshi, additional, Akashi, Yoshihiro, additional, Kotoku, Nozomi, additional, Ikari, Yuji, additional, Maruyama, Mitsunori, additional, Sato, Yasuhiro, additional, Tamura, Koichi, additional, Konishi, Masaaki, additional, Suzuki, Hiroshi, additional, Ebato, Mio, additional, Fukui, Kazuki, additional, Yumoto, Kazuhiko, additional, Iwasawa, Takamasa, additional, Kashimura, Takeshi, additional, Takahashi, Kazuyoshi, additional, Okada, Yoshinobu, additional, Kaku, Bunji, additional, Usuda, Kazuo, additional, Maruyama, Michiro, additional, Kameyama, Tomoki, additional, Higashikata, Toshinori, additional, Hodatsu, Akihiko, additional, Osato, Kazuo, additional, Nagata, Yoji, additional, Maeno, Koji, additional, Satake, Kazuo, additional, Sawanobori, Takao, additional, Watanabe, Noboru, additional, Kuwahara, Koichiro, additional, Motoki, Hirohiko, additional, Kitabayashi, Hiroshi, additional, Otagiri, Kyuhachi, additional, Kono, Tsunesuke, additional, Yamagishi, Daisuke, additional, Yazaki, Yoshikazu, additional, Noda, Toshiyuki, additional, Morishima, Itsuro, additional, Watanabe, Naoki, additional, Tanaka, Shinichiro, additional, Onodera, Tomoya, additional, Nawada, Ryuzo, additional, Watanabe, Akinori, additional, Matsunaga, Masaki, additional, Suwa, Satoru, additional, Sakamoto, Hiroshi, additional, Sakamoto, Hiroki, additional, Aoyama, Takeshi, additional, Kanamori, Norio, additional, Muto, Masahiro, additional, Maekawa, Yuichiro, additional, Ohtani, Hayato, additional, Ozaki, Yukio, additional, Naruse, Kenshin, additional, Takemoto, Kenji, additional, Kamiya, Haruo, additional, Suzuki, Takeshi, additional, Tomita, Yasushi, additional, Suzuki, Susumu, additional, Kametani, Ryosuke, additional, Aoyama, Hidekazu, additional, Osanai, Hiroyuki, additional, Harada, Ken, additional, Kada, Kenji, additional, Saeki, Tomoaki, additional, Kobayashi, Koichi, additional, Ogawa, Yasuhiro, additional, Terasawa, Akihiro, additional, Shinoda, Masanori, additional, Oguri, Mitsutoshi, additional, Shimizu, Kiyokazu, additional, Sawamura, Akinori, additional, Sugiura, Atsushi, additional, Hattori, Kosuke, additional, Mokuno, Shinji, additional, Kondo, Kazuhisa, additional, Dohi, Kaoru, additional, Moriwaki, Keishi, additional, Kasai, Atsunobu, additional, Nakakuki, Tetsuya, additional, Kaitani, Kazuaki, additional, Jinnai, Toshikazu, additional, Yamamoto, Takashi, additional, Kurata, Hiroyuki, additional, Wada, Atsuyuki, additional, Akao, Masaharu, additional, Hamatani, Yasuhiro, additional, Ishibashi, Kazuya, additional, Akakabe, Yoshiki, additional, Asaumi, Yasuhide, additional, Matama, Hideo, additional, Sakata, Yasushi, additional, Kioka, Hidetaka, additional, Takaishi, Hiroshi, additional, Takase, Toru, additional, Matsuda, Mitsuo, additional, Sato, Fumi, additional, Hasegawa, Shinji, additional, Ishigami, Kenichi, additional, Ichikawa, Minoru, additional, Takagi, Takashi, additional, Inoko, Moriaki, additional, Hoshiga, Masaaki, additional, Fujita, Shuichi, additional, Takeda, Yoshihiro, additional, Kawarabayashi, Takahiko, additional, Takaoka, Hideyuki, additional, Nakajima, Kenji, additional, Yuguchi, Tadashi, additional, Kawasaki, Tatsuya, additional, Shinoda, Yukinori, additional, Sato, Yukihito, additional, Ishihara, Masaharu, additional, Matsumoto, Yuki, additional, Kawai, Hiroya, additional, Takaya, Tomofumi, additional, Matsuo, Kouki, additional, Mano, Toshiaki, additional, Hirata, Kenichi, additional, Hisamatsu, Eriko, additional, Inoue, Nobutaka, additional, Tamita, Koichi, additional, Mukohara, Naoki, additional, Shimoyama, Hisashi, additional, Miyajima, Toru, additional, Tamura, Toshihiro, additional, Tamaki, Yodo, additional, Suzuki, Megumi, additional, Yokota, Ryoji, additional, Horii, Manabu, additional, Yamanaka, Kazuo, additional, Kawata, Hiroyuki, additional, Hashimoto, Yukihiro, additional, Nakada, Yasuki, additional, Nakagawa, Hitoshi, additional, Ueda, Tomoya, additional, Nishida, Taku, additional, Seno, Ayako, additional, Watanabe, Makoto, additional, Akasaka, Takashi, additional, Tanimoto, Takashi, additional, Toyofuku, Mamoru, additional, Yamamoto, Kazuhiro, additional, Kinugasa, Yoshiharu, additional, Hirai, Masayuki, additional, Nasu, Hiroshi, additional, Shirota, Kinya, additional, Oda, Tsuyoshi, additional, Oka, Takefumi, additional, Kadota, Kazushige, additional, Ohya, Masanobu, additional, Ito, Hiroshi, additional, Nakamura, Kazufumi, additional, Ogura, Soichiro, additional, Fuke, Soichiro, additional, Uemura, Shiro, additional, Matsubara, Hiromi, additional, Watanabe, Atsuyuki, additional, Morishima, Nobuyuki, additional, Kihara, Yasuki, additional, Hidaka, Takayuki, additional, Ueda, Hironori, additional, Ono, Yujiro, additional, Muraoka, Yuji, additional, Hatanari, Miyo, additional, Miyamoto, Yoshinori, additional, Dote, Keigo, additional, Kato, Masaya, additional, Yano, Masafumi, additional, Mochizuki, Mamoru, additional, Ikeda, Yasuhiro, additional, Fujinaga, Hiroyuki, additional, Hosokawa, Shinobu, additional, Sata, Masataka, additional, Yamaguchi, Koji, additional, Aki, Naoko, additional, Minamino, Tetsuo, additional, Miyake, Yuichi, additional, Takagi, Yuichiro, additional, Doi, Masayuki, additional, Taketani, Yoshio, additional, Okayama, Hideki, additional, Shigematsu, Tatsuya, additional, Higaki, Akinori, additional, Yamaguchi, Osamu, additional, Inaba, Shinji, additional, Ikeda, Shuntaro, additional, Kawai, Kazuya, additional, Kitaoka, Hiroaki, additional, Kubo, Toru, additional, Ando, Kenji, additional, Inui, Kaoru, additional, Fukumoto, Yoshihiro, additional, Hori, Kensuke, additional, Homma, Takehiro, additional, Kawasaki, Tomohiro, additional, Mohri, Masahiro, additional, Fujiwara, Masaki, additional, Tsutsui, Hiroyuki, additional, Ide, Tomomi, additional, Miura, Shin-Ichiro, additional, Kuwano, Takashi, additional, Shimomura, Hideki, additional, Kadokami, Toshiaki, additional, Taba, Masanao, additional, Kondou, Katsuhiro, additional, Kubota, Toru, additional, Nagatomo, Daisuke, additional, Mukai, Yasushi, additional, Matsukawa, Ryuichi, additional, Tashiro, Hideki, additional, Shimomura, Mitsuhiro, additional, Maemura, Koji, additional, Kawano, Hiroaki, additional, Oku, Koji, additional, Yamasa, Toshihiko, additional, Kizaki, Yoshihisa, additional, Sakamoto, Tomohiro, additional, Tamura, Yudai, additional, Ito, Teruhiko, additional, Fujimoto, Kazuteru, additional, Tsujita, Kenichi, additional, Takashio, Seiji, additional, Kurokawa, Hirofumi, additional, Takahashi, Naohiko, additional, Saito, Shotaro, additional, Arikawa, Masaya, additional, Shibata, Yoshisato, additional, Nishihira, Kensaku, additional, Tsuruda, Toshihiro, additional, Sonoda, Masahiro, additional, Atsuchi, Nobuhiko, additional, Ohishi, Mitsuru, additional, Higuchi, Koji, additional, Miyata, Masaaki, additional, Oketani, Naoya, additional, Akimoto, Yoshinori, additional, Asahi, Tomohiro, additional, and Wake, Minoru, additional
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- 2022
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21. Development and appropriateness of a scoring method for International Classification of Functioning, Disabilities, and Health assessment in older patients with heart failure: a Delphi survey of expert panel in Japan
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Shiota, Shigehito, primary, Kitagawa, Toshiro, additional, Goto, Naoya, additional, Fujisita, Hironori, additional, Tamekuni, Yurika, additional, Nakayama, Susumu, additional, Mio, Naoki, additional, Kanai, Kana, additional, Naka, Makiko, additional, Yamaguchi, Mizuho, additional, Mochizuki, Mariko, additional, Ochikubo, Hiroyuki, additional, Hidaka, Takayuki, additional, Yasunobu, Yuji, additional, Nakano, Yukiko, additional, Kihara, Yasuki, additional, and Kimura, Hiroaki, additional
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- 2022
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22. Significant Correlates of Nocturnal Hypertension in Patients With Hypertension Who Are Treated With Antihypertensive Drugs.
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Maruhashi, Tatsuya, Kinoshita, Yoshihiko, Ozono, Ryoji, Nakamaru, Mitsuaki, Ninomiya, Masanori, Oiwa, Jiro, Kawagoe, Takuji, Yoshida, Osamu, Matsumoto, Toshiyuki, Fukunaga, Yasuo, Sumii, Kotaro, Ueda, Hironori, Shiode, Nobuo, Takahari, Kosuke, Hayashi, Yasuhiko, Ono, Yujiro, Nakano, Yukiko, Takahashi, Masakazu, Kihara, Yasuki, and Higashi, Yukihito
- Subjects
AMBULATORY blood pressure monitoring ,ANTIHYPERTENSIVE agents ,HYPERTENSION ,RECEIVER operating characteristic curves ,BLOOD pressure ,CLINICAL trial registries - Abstract
Background Nocturnal hypertension assessed by a home blood pressure monitoring (HBPM) device is associated with an increased risk of cardiovascular events. However, it is still difficult to assess nighttime blood pressure (BP) frequently. The purpose of this cross-sectional study was to identify significant correlates of nocturnal hypertension assessed by an HBPM device in patients with hypertension who are treated with antihypertensive drugs. Methods We measured nighttime BP, morning BP, and evening BP by an HBPM device for 7 consecutive days in 365 medicated patients with hypertension. Results Of the 365 subjects, 138 (37.8%) had nocturnal hypertension defined as a mean nighttime systolic BP of ≥ 120 mm Hg. Receiver operating characteristic curve analyses showed that the diagnostic accuracy of morning systolic BP for subjects with nocturnal hypertension was significantly superior to that of evening systolic BP (P = 0.04) and that of office systolic BP (P < 0.001). Multivariate analysis revealed that morning systolic BP of 125–<135 mm Hg (odds ratio [OR], 2.26; 95% confidence interval [CI], 1.13–4.58; P = 0.02), morning systolic BP of ≥ 135 mm Hg (OR, 16.4; 95% CI, 8.20–32.7; P < 0.001), and a history of cerebrovascular disease (OR, 3.99; 95% CI, 1.75–9.13; P = 0.001) were significantly associated with a higher risk of nocturnal hypertension and that bedtime dosing of antihypertensive drugs was significantly associated with a lower risk of nocturnal hypertension (OR, 0.56; 95% CI, 0.32–0.97; P = 0.04). Conclusions Morning systolic BP of ≥ 125 mm Hg, a history of cerebrovascular disease, and bedtime dosing were significant correlates of nocturnal hypertension in medicated patients with hypertension, and may help detect this risky BP condition. Clinical trials registration University Hospital Medical Information Network Clinical Trials Registry (UMIN000019173). [ABSTRACT FROM AUTHOR]
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- 2023
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23. GJA1遺伝子多型マイナーアレルは心房細動中の高心拍数に関与している
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Okamura, Sho, primary, Onohara, Yuko, additional, Ochi, Hidenori, additional, Tokuyama, Takehito, additional, Okubo, Yosaku, additional, Ikeuchi, Yoshihiro, additional, Miyauchi, Shunsuke, additional, Miyamoto, Shogo, additional, Uotani, Yukimi, additional, Chayama, Kazuaki, additional, Kihara, Yasuki, additional, and Nakano, Yukiko, additional
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- 2022
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24. Modifiers of the Risk of Diabetes for Long-Term Outcomes After Coronary Revascularization
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Yamaji, Kyohei, primary, Shiomi, Hiroki, additional, Morimoto, Takeshi, additional, Matsumura-Nakano, Yukiko, additional, Ehara, Natsuhiko, additional, Sakamoto, Hiroki, additional, Takeji, Yasuaki, additional, Yoshikawa, Yusuke, additional, Yamamoto, Ko, additional, Kato, Eri T., additional, Imada, Kazuaki, additional, Tada, Takeshi, additional, Taniguchi, Ryoji, additional, Nishikawa, Ryusuke, additional, Tada, Tomohisa, additional, Uegaito, Takashi, additional, Ogawa, Tatsuya, additional, Yamada, Miho, additional, Takeda, Teruki, additional, Eizawa, Hiroshi, additional, Tamura, Nobushige, additional, Tambara, Keiichi, additional, Suwa, Satoru, additional, Shirotani, Manabu, additional, Tamura, Toshihiro, additional, Inoko, Moriaki, additional, Nishizawa, Junichiro, additional, Natsuaki, Masahiro, additional, Sakai, Hiroshi, additional, Yamamoto, Takashi, additional, Kanemitsu, Naoki, additional, Ohno, Nobuhisa, additional, Ishii, Katsuhisa, additional, Marui, Akira, additional, Tsuneyoshi, Hiroshi, additional, Terai, Yasuhiko, additional, Nakayama, Shogo, additional, Yamazaki, Kazuhiro, additional, Takahashi, Mamoru, additional, Tamura, Takashi, additional, Esaki, Jiro, additional, Miki, Shinji, additional, Onodera, Tomoya, additional, Mabuchi, Hiroshi, additional, Furukawa, Yutaka, additional, Tanaka, Masaru, additional, Komiya, Tatsuhiko, additional, Soga, Yoshiharu, additional, Hanyu, Michiya, additional, Domei, Takenori, additional, Ando, Kenji, additional, Kadota, Kazushige, additional, Minatoya, Kenji, additional, Nakagawa, Yoshihisa, additional, Kimura, Takeshi, additional, Matsuda, Mitsuo, additional, Takeuchi, Yuzo, additional, Mitsuoka, Hirokazu, additional, Konishi, Takashi, additional, Ootani, Seiji, additional, Fujiwara, Hisayoshi, additional, Takatsu, Yoshiki, additional, Sato, Yukihito, additional, Kataoka, Kazuaki, additional, Nohara, Ryuji, additional, Nakano, Kimisato, additional, Miyamoto, Syoichi, additional, Kunihiko, Nagai, additional, Murakami, Tomoyuki, additional, Ishida, Katsuya, additional, Nobuyoshi, Masakiyo, additional, Yamaji, Kyohei, additional, Yasumoto, Hitoshi, additional, Iwabuchi, Masashi, additional, Kato, Masayuki, additional, Tatami, Ryozo, additional, Hattori, Ryuichi, additional, Kita, Toru, additional, Kihara, Yasuki, additional, Kato, Hiroshi, additional, Aoyama, Takeshi, additional, Sakurai, Takahiro, additional, Kawanami, Masaki, additional, Suyama, Tamaki, additional, Tada, Eiji, additional, Inada, Tsukasa, additional, Uzui, Hiroyasu, additional, Nakano, Akira, additional, Lee, Jong-Dae, additional, Takizawa, Akinori, additional, Ryuzo, Nawada, additional, Shinoda, Eiji, additional, Takahashi, Masaaki, additional, Horie, Minoru, additional, Takashima, Hiroyuki, additional, Toyofuku, Mamoru, additional, Kotoura, Hajime, additional, Miura, Akira, additional, Matoba, Yoshiki, additional, Takumi, Takuro, additional, Tei, Chuwa, additional, Hamasaki, Shuichi, additional, Doi, Osamu, additional, Kambara, Hirofumi, additional, Kaburagi, Satoshi, additional, Mitsudo, Kazuaki, additional, Mizoguchi, Tetsu, additional, Akira, Yoshida, additional, Kaneda, Kazuhisa, additional, Ogawa, Hisao, additional, Sugamura, Koichi, additional, Sugiyama, Seigo, additional, Doyama, Kiyoshi, additional, Araki, Makoto, additional, Sakata, Ryuzo, additional, Ikeda, Tadashi, additional, Onoe, Masahiko, additional, Yamanaka, Kazuo, additional, Iwakura, Atsushi, additional, Fujiwara, Keiichi, additional, Soga, Kinji, additional, Matsushita, Tsutomu, additional, Nishiwaki, Noboru, additional, Yoshida, Yuichi, additional, Okada, Yukikatsu, additional, Nasu, Michihiro, additional, Koyama, Tadaaki, additional, Tanaka, Kuniyoshi, additional, Koshiji, Takaaki, additional, Morioka, Koichi, additional, Shimamoto, Mitsuomi, additional, Yamazaki, Fumio, additional, Aota, Masaki, additional, Hara, Hiroyuki, additional, Tabata, Takafumi, additional, Imoto, Yutaka, additional, Yamamoto, Hiroyuki, additional, Matsuda, Katsuhiko, additional, Nara, Masafumi, additional, Nakajima, Hiroyuki, additional, Kawasuji, Michio, additional, Moriyama, Syuji, additional, Arimura, Sakiko, additional, Fujino, Yumika, additional, Hanazawa, Miya, additional, Hibi, Chikako, additional, Kato, Risa, additional, Kinoshita, Yui, additional, Kitagawa, Kumiko, additional, Kitamura, Masayo, additional, Kuwahara, Takahiro, additional, Sachiko, Maeda, additional, Miki, Izumi, additional, Minematsu, Saeko, additional, Nishida, Satoko, additional, Okamoto, Naoko, additional, Saeki, Asuka, additional, Sasae, Hitomi, additional, Sato, Yuki, additional, Takahashi, Asuka, additional, Takinami, Emi, additional, Tezuka, Saori, additional, Tsuda, Marina, additional, Tsumori, Miyuki, additional, Uchida, Yuriko, additional, Yamamoto, Yuko, additional, Yamauchi, Misato, additional, Yamazaki, Itsuki, additional, Yoshimoto, Mai, additional, Abe, Mitsuru, additional, Fuki, Masayuki, additional, Hayano, Mamoru, additional, Kato, Eri, additional, Kato, Yoshihiro, additional, Nakajima, Tetsu, additional, Nakatsuma, Kenji, additional, Tazaki, Junichi, additional, Tokushige, Akihiro, additional, Watanabe, Hiroki, additional, Yaku, Hidenori, additional, Yamamoto, Erika, additional, and Yamashita, Yugo, additional
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- 2022
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25. Plasma MicroRNAs as noninvasive diagnostic biomarkers in patients with Brugada syndrome
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Ikeuchi, Yoshihiro, primary, Ochi, Hidenori, additional, Motoda, Chikaaki, additional, Tokuyama, Takehito, additional, Okubo, Yousaku, additional, Okamura, Sho, additional, Miyauchi, Syunsuke, additional, Miyamoto, Shogo, additional, Uotani, Yukimi, additional, Onohara, Yuko, additional, Nakashima, Mika, additional, Akiyama, Rie, additional, Tahara, Hidetoshi, additional, Chayama, Kazuaki, additional, Kihara, Yasuki, additional, and Nakano, Yukiko, additional
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- 2022
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26. Comparison of Cryoballoon and Contact Force-Sensing Radiofrequency Ablation for Persistent Atrial Fibrillation in Clinical Practice
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Kobori, Atsushi, primary, Sasaki, Yasuhiro, additional, Pak, Misun, additional, Ishikura, Masahiro, additional, Murai, Ryosuke, additional, Okada, Taiji, additional, Toyota, Toshiaki, additional, Taniguchi, Tomohiko, additional, Kim, Kitae, additional, Ehara, Natsuhiko, additional, Kinoshita, Makoto, additional, Kihara, Yasuki, additional, and Furukawa, Yutaka, additional
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- 2022
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27. Relationship between Diabetes Mellitus and Serum Lathosterol and Campesterol Levels: The CACHE Study DM Analysis
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Matsumura, Takeshi, primary, Ishigaki, Yasushi, additional, Nakagami, Tomoko, additional, Akiyama, Yusuke, additional, Ishibashi, Yutaka, additional, Ishida, Tatsuro, additional, Fujii, Hisako, additional, Harada-Shiba, Mariko, additional, Kabata, Daijiro, additional, Kihara, Yasuki, additional, Kotani, Kazuhiko, additional, Kurisu, Satoshi, additional, Masuda, Daisaku, additional, Matoba, Tetsuya, additional, Matsuki, Kota, additional, Mori, Kenta, additional, Nakazato, Masamitsu, additional, Taniuchi, Satsuki, additional, Ueno, Hiroaki, additional, Yamashita, Shizuya, additional, Yoshida, Hiroshi, additional, Yoshida, Hisako, additional, and Shoji, Tetsuo, additional
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- 2022
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28. Acupuncture: Could it be a treatment for angina pectoris?
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Teragawa, Hiroki, Oshita, Chikage, Orita, Yuichi, and Kihara, Yasuki
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- 2024
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29. Acupuncture: Could it be a treatment for angina pectoris?
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Teragawa, Hiroki, Oshita, Chikage, Orita, Yuichi, and Kihara, Yasuki
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- 2021
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30. Chronic Effects of Adaptive Servo-Ventilation Therapy on Mortality and the Urgent Rehospitalization Rate in Patients Experiencing Recurrent Admissions for Heart Failure - A Multicenter Prospective Observational Study (SAVIOR-L).
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Fukumoto Y, Tada T, Suzuki H, Nishimoto Y, Moriuchi K, Arikawa T, Adachi H, Momomura SI, Seino Y, Yasumura Y, Yokoyama H, Hiasa G, Hidaka T, Nohara S, Okayama H, Tsutsui H, Kasai T, Takata Y, Enomoto M, Saigusa Y, Yamamoto K, Kinugawa K, and Kihara Y
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- Humans, Aged, Male, Female, Prospective Studies, Aged, 80 and over, Japan epidemiology, Middle Aged, Time Factors, Treatment Outcome, Heart Failure mortality, Heart Failure therapy, Patient Readmission statistics & numerical data
- Abstract
Background: This study investigated whether the chronic use of adaptive servo-ventilation (ASV) reduces all-cause mortality and the rate of urgent rehospitalization in patients with heart failure (HF)., Methods and results: This multicenter prospective observational study enrolled patients hospitalized for HF in Japan between 2019 and 2020 who were treated either with or without ASV therapy. Of 845 patients, 110 (13%) received chronic ASV at hospital discharge. The primary outcome was a composite of all-cause death and urgent rehospitalization for HF, and was observed in 272 patients over a 1-year follow-up. Following 1:3 sequential propensity score matching, 384 patients were included in the subsequent analysis. The median time to the primary outcome was significantly shorter in the ASV than in non-ASV group (19.7 vs. 34.4 weeks; P=0.013). In contrast, there was no significant difference in the all-cause mortality event-free rate between the 2 groups., Conclusions: Chronic use of ASV did not impact all-cause mortality in patients experiencing recurrent admissions for HF.
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- 2024
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31. Relationship between Diabetes Mellitus and Serum Lathosterol and Campesterol Levels: The CACHE Study DM Analysis.
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Matsumura T, Ishigaki Y, Nakagami T, Akiyama Y, Ishibashi Y, Ishida T, Fujii H, Harada-Shiba M, Kabata D, Kihara Y, Kotani K, Kurisu S, Masuda D, Matoba T, Matsuki K, Mori K, Nakazato M, Taniuchi S, Ueno H, Yamashita S, Yoshida H, Yoshida H, and Shoji T
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- Humans, Female, Middle Aged, Male, Glycated Hemoglobin, Cholesterol, Ezetimibe, Biomarkers, Hydroxymethylglutaryl-CoA Reductase Inhibitors therapeutic use, Phytosterols, Diabetes Mellitus
- Abstract
Aim: Risk of cardiovascular disease is increased in patients with diabetes mellitus (DM). Cholesterol metabolism (hepatic synthesis and intestinal absorption) is known to be associated with cardiovascular risk. Next, we examined the association of DM with cholesterol absorption/synthesis., Methods: The CACHE Consortium, which is comprised of 13 research groups in Japan possessing data of lathosterol (Latho, synthesis marker) and campesterol (Campe, absorption marker) measured by gas chromatography, compiled the clinical data using the REDCap system. Among the 3597 records, data from 2944 individuals were used for several analyses including this study., Results: This study analyzed data from eligible 2182 individuals including 830 patients with DM; 42.2% were female, median age was 59 years, and median HbA1c of patients with DM was 7.0%. There was no difference in Latho between DM and non-DM individuals. Campe and Campe/Latho ratio were significantly lower in DM individuals than in non-DM individuals. When the associations of glycemic control markers with these markers were analyzed with multivariable-adjusted regression model using restricted cubic splines, Campe and Campe/Latho ratio showed inverse associations with glucose levels and HbA1c. However, Latho showed an inverted U-shaped association with plasma glucose, whereas Latho showed a U-shaped association with HbA1c. These associations remained even after excluding statin and/or ezetimibe users., Conclusion: We demonstrated that DM and hyperglycemia were independent factors for lower cholesterol absorption marker levels regardless of statin/ezetimibe use.
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- 2023
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32. JCS/JHFS 2021 Guideline Focused Update on Diagnosis and Treatment of Acute and Chronic Heart Failure.
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Tsutsui H, Ide T, Ito H, Kihara Y, Kinugawa K, Kinugawa S, Makaya M, Murohara T, Node K, Saito Y, Sakata Y, Shimizu W, Yamamoto K, Bando Y, Iwasaki YK, Kinugasa Y, Mizote I, Nakagawa H, Oishi S, Okada A, Tanaka A, Akasaka T, Ono M, Kimura T, Kosaka S, Kosuge M, and Momomura SI
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- Chronic Disease, Humans, Heart Failure diagnosis, Heart Failure therapy
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- 2021
- Full Text
- View/download PDF
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