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Chronic Effects of Adaptive Servo-Ventilation Therapy on Mortality and the Urgent Rehospitalization Rate in Patients Experiencing Recurrent Admissions for Heart Failure - A Multicenter Prospective Observational Study (SAVIOR-L).
- Source :
-
Circulation journal : official journal of the Japanese Circulation Society [Circ J] 2024 Apr 25; Vol. 88 (5), pp. 692-702. Date of Electronic Publication: 2024 Apr 12. - Publication Year :
- 2024
-
Abstract
- Background: This study investigated whether the chronic use of adaptive servo-ventilation (ASV) reduces all-cause mortality and the rate of urgent rehospitalization in patients with heart failure (HF).<br />Methods and results: This multicenter prospective observational study enrolled patients hospitalized for HF in Japan between 2019 and 2020 who were treated either with or without ASV therapy. Of 845 patients, 110 (13%) received chronic ASV at hospital discharge. The primary outcome was a composite of all-cause death and urgent rehospitalization for HF, and was observed in 272 patients over a 1-year follow-up. Following 1:3 sequential propensity score matching, 384 patients were included in the subsequent analysis. The median time to the primary outcome was significantly shorter in the ASV than in non-ASV group (19.7 vs. 34.4 weeks; P=0.013). In contrast, there was no significant difference in the all-cause mortality event-free rate between the 2 groups.<br />Conclusions: Chronic use of ASV did not impact all-cause mortality in patients experiencing recurrent admissions for HF.
Details
- Language :
- English
- ISSN :
- 1347-4820
- Volume :
- 88
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Circulation journal : official journal of the Japanese Circulation Society
- Publication Type :
- Academic Journal
- Accession number :
- 38569914
- Full Text :
- https://doi.org/10.1253/circj.CJ-23-0827