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Your search keyword '"Keisuke Kurihara"' showing total 9 results
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9 results on '"Keisuke Kurihara"'

1. Acute necrotic disorder of the small intestine post‐coronavirus disease‐2019 vaccination

Author

Tomoyuki Nishimura, Seiji Onogawa, Takuya Yamamoto, Yasuhiro Okuda, Morito Ikeda, Nozomu Matsumoto, Keisuke Kurihara, Akinori Shimizu, Shosuke Kitamura, Yoshio Katamura, Naomichi Hirano, Shingo Itamoto, Masahiro Nakahara, Shuji Yonehara, Fumio Shimamoto, and Keiji Hanada

Subjects
COVID‐19, necrosis, side effects, small intestine, vaccines, Diseases of the digestive system. Gastroenterology, RC799-869
Abstract

Abstract The Pfizer‐BioNTech coronavirus disease 2019 (COVID‐19) vaccine is extensively used worldwide, and its safety has been proven. Herein, we report a case of an acute necrotic disorder in the small intestine post‐COVID‐19 vaccination. The patient developed severe abdominal pain the day after the first vaccination. Contrast‐enhanced computed tomography showed extensive ileum wall thickening and ascites. Colonoscopy revealed a ring‐shaped ulcer and stricture in the terminal ileum. Ileocecal resection was performed, and the patient did not have further episodes of a necrotic disorder in the small intestine. Although it is unknown if this event is associated with vaccination, and this occurrence also does not outweigh the efficacy and safety of the Pfizer‐BioNTech COVID‐19 vaccine, gastroenterologists need to be aware of this rare case, given its noteworthy timing.

Published
2023
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6. Curative surgery for primary squamous cell carcinoma of the liver: a rare case study

Author

Yasuhiro Okuda, Tomoyuki Abe, Morito Ikeda, Keisuke Kurihara, Akinori Shimizu, Akihiko Oshita, Shuji Yonehara, and Keiji Hanada

Subjects
Gastroenterology, General Medicine
Abstract

Primary squamous cell carcinoma (SCC) of the liver is an extremely rare disease with a very poor prognosis. An 83-year-old woman was referred to our hospital with left abdominal pain. Laboratory data showed mildly elevated C-reactive protein and biliary enzymes. The tumor markers carcinoembryonic antigen, alpha-fetoprotein, and carbohydrate antigen 19-9 were within normal ranges. Contrast-enhanced computed tomography revealed a 60 mm-sized low-density mass with poor contrast enhancement located in the lateral segment of the liver. The tumor showed low signal on T

Published
2022

8. Observation of Surface Potential of Micropatterned Self-assembled Electrets for MEMS Vibrational Energy Harvesters.

Author

Daisuke Yamane, Kosuke Kawashima, Reiki Sugimoto, Ruichen Li, Hideyuki Kayaguchi, Keisuke Kurihara, Hisao Ishi, and Yuya Tanaka

Subjects
SURFACE potential, ELECTRETS, MICROFABRICATION
Abstract

In this paper, we present the observation results of the surface potential of micropattemed thick (> 1 pm) self-assembled electrets (SAEs) for MEMS vibrational energy harvesters (VEHs). To evaluate the surface potential of micropattemed SAEs, we propose and develop test devices with removable through-hole substrates corresponding to the moving electrodes of SAE-MEMS VEHs. In this study, SAEs are deposited simultaneously on two test devices with different through-hole spacings and on a reference flat substrate using the same vacuum evaporation process. The surface potential of SAEs is proportional to the film thickness, and when the film thickness of the SAE deposited on the flat substrate is 4.48 pm, the surface potential exceeds 200 V. At this time, in a test device where the average thickness of micropattemed SAEs is 3.08 pm, the measured surface potential is 68 V. In addition, it is experimentally observed that when micropattemed SAEs are formed using the through-hole structures, the microfabrication process causes the SAE pattern to spread wider than the through-hole dimensions, and the surface profiles are not flat. These findings provide useful insights for the design of SAE-MEMS VEHs using micropattemed SAEs with through-hole structures. [ABSTRACT FROM AUTHOR]

Published
2023
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9. Endoscopic approach in the diagnosis of high-grade pancreatic intraepithelial neoplasia

Author

Keiji Hanada, Akihiro Shimizu, Keisuke Kurihara, Morito Ikeda, Takuya Yamamoto, Yasuhiro Okuda, and Susumu Tazuma

Subjects
Cholangiopancreatography, Endoscopic Retrograde, Pancreatic Neoplasms, Pancreatic Juice, Gastroenterology, Pancreatic Ducts, Humans, Radiology, Nuclear Medicine and imaging, Constriction, Pathologic, Carcinoma, Pancreatic Ductal, Dilatation, Pathologic
Abstract

Early diagnosis of pancreatic ductal adenocarcinoma (PDAC) is essential for improving prognosis; however, diagnosing PDAC at an early stage is challenging. In patients with localized high-grade pancreatic intraepithelial neoplasia (HG-PanIN), whose tumorous lesion is undetectable on cross-sectional images such as computed tomography or magnetic resonance image, long-term survival is expected. Pancreatic cystic lesions or main pancreatic duct (MPD) dilatation are important indirect findings for the initial diagnosis of HG-PanIN. Magnetic resonance cholangiopancreatography (MRCP) and endoscopic ultrasound (EUS) should play important roles in detecting abnormal image findings, such as local irregular MPD stenosis, caliber MPD changes, small cystic lesions, or branch duct dilatation. Additionally, EUS could detect hypoechoic areas around the MPD stenosis in some patients with HG-PanIN. Subsequently, endoscopic retrograde cholangiopancreatography (ERCP) and its associated pancreatic juice cytology, including serial pancreatic juice aspiration cytologic examination (SPACE) after placement of an endoscopic nasopancreatic drainage (ENPD) tube, may have high diagnostic accuracy for confirming the malignancy in HG-PanIN. Although ERCP and its associated pancreatic cytology, including SPACE, may be associated with post-ERCP pancreatitis (PEP), a recent randomized trial suggested that a 4-Fr ENPD tube may reduce the incidence of PEP. In the future, further prospective multicenter studies are required to establish a standard method of SPACE. Additionally, further studies for novel biomarkers could help to establish evolutionary methods with duodenal fluid and pancreatic juice for the early and accurate diagnosis of early-stage PDAC.

Published
2022

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