31 results on '"Huitao Zhang"'
Search Results
2. Associations of the circulating levels of cytokines with the risk of myeloproliferative neoplasms: a bidirectional mendelian-randomization study
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Hao Xiong, Huitao Zhang, Jun Bai, Yanhong Li, Lijuan Li, and Liansheng Zhang
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Myeloproliferative neoplasms ,Mendelian randomization ,Inflammatory ,Cytokines ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Objective In the pathogenesis of myeloproliferative neoplasms (MPN), inflammation plays an important role. However, it is unclear whether there is a causal link between inflammation and MPNs. We used a bidirectional, two-sample Mendelian randomization (MR) approach to investigate the causal relationship between systemic inflammatory cytokines and myeloproliferative neoplasms. Methods A genome-wide association study (GWAS) of 8293 European participants identified genetic instrumental variables for circulating cytokines and growth factors. Summary statistics of MPN were obtained from a GWAS including 1086 cases and 407,155 controls of European ancestry. The inverse-variance-weighted method was mainly used to compute odds ratios (OR) and 95% confidence intervals (Cl). Results Our results showed that higher Interleukin-2 receptor, alpha subunit (IL-2rα) levels, and higher Interferon gamma-induced protein 10 (IP-10) levels were associated with an increased risk of MPN (OR = 1.36,95%CI = 1.03–1.81, P = 0.032; OR = 1.55,95%CI = 1.09–2.22, P = 0.015; respectively).In addition, Genetically predicted MPN promotes expression of the inflammatory cytokines interleukin-10 (IL-10) (BETA = 0.033, 95% CI = 0.003 ~ 0.064, P = 0.032) and monokine induced by interferon-gamma (MIG) (BETA = 0.052, 95% CI = 0.002–0.102, P = 0.043) and, on activation, normal T cells express and secrete RANTES (BETA = 0.055, 95% CI = 0.0090.1, P = 0.018). Conclusion Our findings suggest that cytokines are essential to the pathophysiology of MPN. More research is required if these biomarkers can be used to prevent and treat MPN.
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- 2024
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3. Grating-based x-ray dark-field CT for lung cancer diagnosis in mice
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Peiyuan Guo, Li Zhang, Jincheng Lu, Huitao Zhang, Xiaohua Zhu, Chengpeng Wu, Xiangwen Zhan, Hongxia Yin, Zhenchang Wang, Yan Xu, and Zhentian Wang
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Disease progression ,Early detection of cancer ,Lung diseases ,Tomography (x-ray computed) ,X-rays ,Medical physics. Medical radiology. Nuclear medicine ,R895-920 - Abstract
Abstract Background The low absorption of x-rays in lung tissue and the poor resolution of conventional computed tomography (CT) limits its use to detect lung disease. However, x-ray dark-field imaging can sense the scattered x-rays deflected by the structures being imaged. This technique can facilitate the detection of small alveolar lesions that would be difficult to detect with conventional CT. Therefore, it may provide an alternative imaging modality to diagnose lung disease at an early stage. Methods Eight mice were inoculated with lung cancers simultaneously. Each time two mice were scanned using a grating-based dark-field CT on days 4, 8, 12, and 16 after the introduction of the cancer cells. The detectability index was calculated between nodules and healthy parenchyma for both attenuation and dark-field modalities. High-resolution micro-CT and pathological examinations were used to crosscheck and validate our results. Paired t-test was used for comparing the ability of dark-field and attenuation modalities in pulmonary nodule detection. Results The nodules were shown as a signal decrease in the dark-field modality and a signal increase in the attenuation modality. The number of nodules increased from day 8 to day 16, indicating disease progression. The detectability indices of dark-field modality were higher than those of attenuation modality (p = 0.025). Conclusions Compared with the standard attenuation CT, the dark-field CT improved the detection of lung nodules. Relevance statement Dark-field CT has a higher detectability index than conventional attenuation CT in lung nodule detection. This technique could improve the early diagnosis of lung cancer. Key points • Lung cancer progression was observed using x-ray dark-field CT. • Dark-field modality complements with attenuation modality in lung nodule detection. • Dark-field modality showed a detectability index higher than that attenuation in nodule detection. Graphical Abstract
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- 2024
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4. A spider mating plug functions to protect sperm.
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He Jiang, Yongjia Zhan, Qingqing Wu, Huitao Zhang, Matjaž Kuntner, and Lihong Tu
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Medicine ,Science - Abstract
Mating plugs in animals are ubiquitous and are commonly interpreted to be products of mating strategies. In spiders, however, mating plugs may also take on functions beyond female remating prevention. Due to the vagaries of female genital (spermathecal) anatomy, most spiders face the problem of having to secure additional, non-anatomical, protection for transferred sperm. Here, we test the hypothesis that mating plugs, rather than (or in addition to) being adaptations for mating strategies, may serve as sperm protection mechanism. Based on a comparative study on 411 epigyna sampled from 36 families, 187 genera, 330 species of entelegyne spiders, our results confirm the necessity of a sperm protection mechanism. We divided the entelegyne spermathecae into four types: SEG, SED, SCG and SCD. We also studied detailed morphology of epigynal tracts in the spider Diphya wulingensis having the SEG type spermathecae, using 3D-reconstruction based on semi thin histological series section. In this species, we hypothesize that two distinct types of mating plug, the sperm plug and the secretion plug, serve different functions. Morphological details support this: sperm plugs are formed on a modified spermathecal wall by the spilled sperm, and function as a temporary protection mechanism to prevent sperm from leaking and desiccating, while secretion plugs function in postcopulation both as a permanent protection mechanism, and to prevent additional mating. Furthermore, with the modified spermathecal wall of S2 stalk, the problem of shunt of sperm input and output, and the possibility of female multiple mating have been resolved. Variation in spermathecal morphology also suggests that the problem of sperm protection might be resolved in different ways in spiders. Considering mating plugs of varying shapes and origins in the vast morphospace of spiders, we conclude that mating plugs might serve different purposes that relate both to mating strategies, as well as to sperm protection.
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- 2024
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5. Fracture-vuggy carbonate reservoir characterization based on multiple geological information fusion
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Yan Wang, Pengfei Xie, Huitao Zhang, Yuming Liu, and Aiying Yang
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carbonate reservoir ,Fractured-vuggy reservoir ,geological modeling ,probability fusion ,fracture ,Science - Abstract
The complexity and strong heterogeneity of carbonate reservoirs with fracture-vuggy structures present significant challenges in reservoir characterization. To address these challenges, we propose a novel multi-element information fusion modeling approach. This approach is designed to integrate multiple methods and incorporate multi-probability fusion at various facies and scales, thereby bridging the gap between geological information and reservoir modeling. Our methodology involves four key steps. First, the statistics between frequency of karst and geological information are acquired, and we quantify the statistics to regression equations. Second, these regression equations are transferred to probability bodies. The probability bodies can be applied in modeling as a soft control. But just one single body can be input in modeling process. Third, multiple probability bodies are fused into a fusion probability body by a probability fusion algorithm, which can keep the potential information of probability bodies. Finally, we apply the probability body in modeling workflow. By this way, the fusion method bridges the gap between geological information and modeling. The model established through our proposed method showed a significant level of consistency with reservoir re-evaluation, achieving an impressive 90% degree of alignment. Furthermore, the history match analysis revealed a high correlation, indicating the model's reliability. The method effectively integrates various scales and types of geological information, offering an accurate approach to complex carbonate reservoir modeling.
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- 2024
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6. Mechanical stimulation on a microfluidic device to highly enhance small extracellular vesicle secretion of mesenchymal stem cells
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Rui Hao, Shi Hu, Huitao Zhang, Xi Chen, Zitong Yu, Jingyi Ren, Hang Guo, and Hui Yang
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Microfluidics ,Small extracellular vesicles ,Mechanical squeezing ,Secretion amount ,Mesenchymal stem cells ,Medicine (General) ,R5-920 ,Biology (General) ,QH301-705.5 - Abstract
Small extracellular vesicles (sEVs) are recognized as promising detection biomarkers and attractive delivery vehicles, showing great potential in diagnosis and treatment of diseases. However, the applications of sEVs are usually restricted by their poor secretion amount from donor cells under routine cell culture conditions, which is especially true for mesenchymal stem cells (MSCs) due to their limited expansion and early senescence. Here, a microfluidic device is proposed for boosting sEV secretion from MSCs derived from human fetal bone marrow (BM-MSCs). As the cells rapidly pass through a microfluidic channel with a series of narrow squeezing ridges, mechanical stimulation permeabilizes the cell membrane, thus promoting them to secrete more sEVs into extracellular space. In this study, the microfluidic device demonstrates that mechanical-squeezing effect could increase the secretion amount of sEVs from the BM-MSCs by approximately 4-fold, while maintaining cellular growth state of the stem cells. Further, the secreted sEVs are efficiently taken up by immortalized human corneal epithelial cells and accelerate corneal epithelial wound healing in vitro, indicating that this technique wound not affect the functionality of sEVs and demonstrating the application potentials of this technique.
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- 2023
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7. Optimization of Protoplast Preparation System from Leaves and Establishment of a Transient Transformation System in Apium graveolens
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Jiageng Du, Huitao Zhang, Weilong Li, Xiaoyan Li, Zhuo Wang, Ying Zhang, Aisheng Xiong, and Mengyao Li
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celery ,protoplast preparation ,transient transformation system ,subcellular localization ,Agriculture - Abstract
Protoplast culture and transformation technology offer a novel method for developing new plant varieties. Nonetheless, the effective preparation of protoplasts and transformation technology specific to celery has yet to be achieved. This study utilized celery seedling leaves as the primary materials to examine the key factors influencing protoplast isolation. The aim was to prepare leaf protoplasts with a high yield and of high quality and subsequently conduct transient gene transformation and expression. The findings indicated that the most effective procedure for isolating and purifying protoplasts was enzymatic digestion using an enzyme solution consisting of 2.0% cellulase, 0.1% pectolase, and 0.6 M mannitol for a duration of 8 h. Subsequently, the protoplasts were filtered through a 400-mesh sieve and purified through centrifugation at 200× g. Within this system, the overall protoplast yield was exceptionally high, reaching a viability rate of up to 95%. The transient transformation system yielded a maximum transformation efficiency of approximately 53%, as evaluated using the green fluorescent protein (GFP) as a reporter gene. The parameters of the transient transformation system were as follows: a protoplast concentration of 5 × 105 cells·mL−1, exogenous DNA concentration of 500 μg·mL−1, final concentration of PEG4000 at 40%, and transformation duration of 15 min. The transient transformation system was also utilized to further analyze the protein localization characteristics of the celery transcription factor AgMYB80. The findings indicated that AgMYB80 predominantly localizes in the nucleus, thereby confirming the reliability and effectiveness of the transient transformation system. This study successfully established an efficient system for isolating, purifying, and transforming celery protoplasts, and will serve as a basis for future studies on molecular biology and gene function.
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- 2023
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8. Chattering suppression of the sliding mode observer for marine electric propulsion motor based on piecewise power function
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Xiangfeng Li, Shengqiang Zhan, Fang Guo, Zidan Zhuang, Huitao Zhang, Hui Liao, and Lili Qu
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PMSM ,sliding mode observer ,sensorless control ,piecewise power function ,chatter suppression ,General Works - Abstract
The sliding mode observer (SMO)–based sensorless control is essentially a discontinuous switching control algorithm. Therefore, there is large speed or torque chattering in the permanent magnet synchronous motor (PMSM) with existing sliding mode observer–based control methods. In order to solve this problem well, an algorithm based on an improved sliding mode observer is proposed. In detail, the piecewise power function approach is used to replace the traditional ones, that is, the sgn function or the sigmoid function approach. Simulation verifications are conducted to validate the effectiveness of the proposed observer. It shows that the piecewise power function–based sliding mode observer algorithm has obvious advantages in the stability of the three-phase current, namely, it improves the estimation accuracy of the rotor position, rotor speed, and dynamic response to various loads. For further verification, the proposed sliding mode observer algorithm is implemented and verified in a marine electric propulsion motor with a DSP chip of TMS320F28377D. Experimental results validate that the piecewise power function–based sliding mode observer algorithm has high control accuracy and fewer fluctuations, which are all vital in marine engineering.
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- 2022
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9. Generation of three lines from multiorgan venous and lymphatic defect syndrome patients
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Xiaojun Hu, Junjie Mao, Ke Zhang, Huitao Zhang, Dan Li, Bin Zhou, Hong Shan, Bing Li, and Pengfei Pang
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Biology (General) ,QH301-705.5 - Abstract
Multiorgan venous and lymphatic defect (MOVLD) syndrome is a unique visceral vascular malformations with complex etiologies. In this study, primary skin fibroblasts were obtained from three MOVLD patients and reprogrammed into iPSCs by Yamanaka’s classical strategy. The MOVLD- iPSCs carrying the DDX24 p.Glu271Lys mutation were confirmed by Sanger sequencing. The pluripotency of MOVLD-iPSCs was verified by the specific molecular markers and gene expression, trilineage differentiation potential. The establishment of the MOVLD-iPSCs will provide a useful model for understanding the mechanisms involved the MOVLD and promoting the development of medical treatment.
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- 2022
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10. Generation of Stable Cell Lines of APP695 (K595N, M596L) Gene Over-Expression via Lentiviral Over-Expression System
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Huitao Zhang, Hao, Rui, Yu, Zitong, Hu, Shi, Ren, Jingyi, Hong, Yanhang, Wang, Shifan, Sun, Huihui, Zhang, Pengcheng, Zhang, Yi, Yang, Hui, and Ding, Juan
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- 2024
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11. Available energy routing algorithm considering QoS requirements for LEO satellite network.
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Li Yang, Huitao Zhang, Yaowen Qi, and Qilong Huang
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- 2024
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12. One-Step Method for Material Quantitation Using In-Line Tomography With Single Scanning.
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Suyu Liao, Shiwo Deng, Yining Zhu, Huitao Zhang, Peiping Zhu, Kai Zhang, and Xing Zhao
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- 2023
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13. Design and implementation of open laboratory management system based on 2DPCA face identification technology.
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Huitao Zhang, Li Yang, Jingwu Sun, and Zhiguo Liu
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- 2022
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14. Fast Iterative Reconstruction for Multi-spectral CT by a Schmidt Orthogonal Modification Algorithm (SOMA).
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Huiying Pan, Shusen Zhao, Weibin Zhang, Huitao Zhang, and Xing Zhao
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- 2022
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15. Influence of different microbial inoculants on nitrogen retention and diazotroph community succession during cotton straw composting
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Liuyan Zhou, Yuqing Xie, Xiaowu Wang, Pengbing Li, Yuyue Liu, Zhifang Wang, Jinping Dai, Huitao Zhang, and Xinping Yang
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Environmental Engineering ,General Chemical Engineering ,Environmental Chemistry ,Safety, Risk, Reliability and Quality - Published
- 2023
16. Nitratireductor luteus sp. nov. isolated from saline-alkali land
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Xinping, Yang, Liuyan, Zhou, Xiaowu, Wang, Zhifang, Wang, Pengbin, Li, Jinping, Dai, Huitao, Zhang, and Yuqing, Xie
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General Medicine ,Molecular Biology ,Microbiology - Abstract
The Gram-staining negative, oxidase and catalase negative strain KC-ST17
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- 2022
17. Hemodialysis Arteriovenous Fistula Dysfunction: Retrospective Comparison of Post-thrombotic Percutaneous Endovascular Interventions with Pre-emptive Angioplasty
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Xinyan Hu, Bing Li, Junjie Mao, Xiaojun Hu, Jingjing Zhang, Hui Guo, Dashuai Wang, Yongyu Zhang, Jianan He, Ni Zhao, Huitao Zhang, and Pengfei Pang
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Angioplasty ,Graft Occlusion, Vascular ,Thrombosis ,General Medicine ,Urokinase-Type Plasminogen Activator ,Arteriovenous Shunt, Surgical ,Treatment Outcome ,Renal Dialysis ,Arteriovenous Fistula ,Humans ,Surgery ,Cardiology and Cardiovascular Medicine ,Angioplasty, Balloon ,Vascular Patency ,Retrospective Studies - Abstract
We aimed to compare the clinical outcomes of pre-emptive angioplasty versus post-thrombotic percutaneous endovascular restoration of dysfunctional arteriovenous fistula (AVF).This retrospective study reviewed the data from 80 patients who underwent 114 endovascular interventions for a malfunctioning AVF from July 2016 to August 2019. Stenotic AVFs were treated with pre-emptive angioplasty. Thrombosed AVFs were treated with percutaneous pharmacomechanical fibrinolysis with urokinase used only during the operation or continuously infused. The differences in patency rates were evaluated using the Kaplan-Meier method. In addition, univariate and multivariate regression Cox models were used to determine influential factors on the postintervention primary patency.Post-thrombotic interventions and pre-emptive angioplasty yielded statistically similar rates in clinical success (100 vs. 100%), anatomic success (94 vs. 89%; P = 0.52), complication (4 vs. 11%; P = 0.29), as well as postintervention primary, assisted primary and secondary patency (P = 0.80; 0.57; 0.57). The use of pre-emptive angioplasty was associated with reduced total cost (¥25,108 vs. ¥30,833, P 0.001). The patients who used urokinase only during the operation prolonged both the primary and assisted primary patency (P = 0.02; 0.002), while those with continuous infusion of urokinase had worst patency rates and high costs (¥39,275 vs. ¥25,108 vs. ¥27,140, P 0.001). Compared with the other locations, dysfunction in the anastomotic or juxta-anastomotic segment (HR = 0.41, P = 0.001) was associated with prolonged postintervention primary patency.No clinical outcome differences were found between the post-thrombotic percutaneous endovascular interventions and pre-emptive angioplasty. However, pre-emptive angioplasty decreased access expenditure.
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- 2022
18. Effects of bacterial inoculation on lignocellulose degradation and microbial properties during cow dung composting.
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Liuyan Zhou, Xinping Yang, Xiaowu Wang, Lei Feng, Zhifang Wang, Jinping Dai, Huitao Zhang, and Yuqing Xie
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- 2023
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19. Reconstruction Algorithm-Based CT Imaging for the Diagnosis of Hepatic Ascites
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Huitao Zhang, Wenhao Lv, Haofeng Diao, and Li Shang
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Article Subject ,General Immunology and Microbiology ,Applied Mathematics ,Ascites ,Water ,General Medicine ,General Biochemistry, Genetics and Molecular Biology ,Artificial Intelligence ,Modeling and Simulation ,Humans ,Radiographic Image Interpretation, Computer-Assisted ,Calcium ,Tomography, X-Ray Computed ,Algorithms ,Iodine - Abstract
The study was aimed at exploring the diagnostic value of artificial intelligence reconstruction algorithm combined with CT image parameters on hepatic ascites, expected to provide a reference for the etiological evaluation of clinical abdominal effusion. Specifically, the adaptive iterative hard threshold (AIHT) algorithm for CT image reconstruction was proposed. Then, 100 patients with peritoneal effusion were selected as the research subjects. After 8 cases were excluded, the remaining was divided into 50 cases of the S1 group (hepatic ascites) and 42 cases of the D0 group (cancerous peritoneal effusion). Gemstone energy spectrum CT scanning was performed on all patients, and CT image parameters of the two groups were compared. It was found that CT value of mixed energy, CT value of 60-100 KeV single energy, concentration value of water (calcium), concentration value of water (iodine), and slope of energy spectrum curve in the S1 group were significantly lower than those in the D0 group ( P < 0.05 ). The effective atomic number in the S1 group was significantly higher than that in the D0 group ( P < 0.05 ). Of the 50 patients in the S1 group, 3 (6%) had an ascending and 47 (94%) had a descending spectral curve. Of the 42 patients in the D0 group, 37 (88.1%) had an ascending and 5 (11.9%) had a descending spectral curve. The sensitivity and specificity of water (iodine) were 0.927 and 0.836, respectively. The sensitivity and specificity of water (calcium) were 0.863 and 0.887, respectively. For different scan ranges ([0,90]; [0,120]), root mean square error (RMSE) of AIHT reconstructed image was significantly smaller than that of traditional algorithm, while peak signal-to-noise ratio (PSNR) was opposite. The differences were statistically significant ( P < 0.05 ). In conclusion, AIHT-based CT images can better display the distribution of hepatic ascites, and the parameters of CT value, effective atomic number, water (iodine), water (calcium), and spectral curve can all provide help for the identification of hepatic ascites. Especially, water (iodine) and water (calcium) demonstrated high diagnostic performance of hepatic ascites.
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- 2022
20. Analysis of Spatial Structure and Filling Mechanism of Paleokarst Conduit Against a Background of Denudation: A Case Study in the Tahe Oilfield, Tarim Basin
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Chenhe Zhang, Zhiqian Gao, Tailiang Fan, Duan Wei, Jun Wua, Debin Yang, Jinxian Liu, Huitao Zhang, Bo Li, Zhe Chang, Yu Gu, Ming Jiang, Ze Gao, Aolin Wang, and Qianxi Zou
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- 2023
21. Protein Post-translational Modification Site Prediction using Deep Learning
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Yujuan Deng, Yunfang Fu, Huitao Zhang, Xin Liu, and Zhiguo Liu
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General Earth and Planetary Sciences ,General Environmental Science - Published
- 2022
22. Encapsulating has-miR-29a into HuMSCs-derived Exosomes by a Nanoengineering Platform to Efficiently Alleviate Aβ1-42 Expression in APPswe-SH-SY5Y Cells
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Huitao Zhang, Hui Yang, Rui Hao, Zitong Yu, Shi Hu, Jingyi Ren, Juan Ding, and Yi Zhang
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Background Exosomes derived from human umbilical cord mesenchymal stem cells (HuMSCs) have been utilized as a potential therapeutic candidate to alleviate amyloid β-protein (Aβ) expression in APP/PS1 or 5XFAD transgenic mice due to their low immunogenicity and extensive sources. Accumulated evidence also suggests that encysting appropriate cargos into exosomes can more effectively reduce Aβ expression by interfering with the metabolism of β-Amyloid precursor protein (APP). Therefore, exosomes loaded with bioactive substances to reduce Aβ expression have attracted much attention. A new strategy to load therapeutic exogenous cargoes of interest into exosomes in a high-throughput and straightforward fashion is desired. Results In this study, neuroblastoma SH-SY5Y cells were stably transfected with Swedish mutant APP695K, 595N plasmid to construct a cell model of Aβ overexpression. Then extracted Exosomes from HuMSCs and loaded with micro (miR)-29a via a microfluidic exosome nanoengineering platform (ExoNP) to target a post-transcriptional modification of the β-secretase1 (β-site APP cleaving enzyme 1, BACE1) gene to prevent protein expression. Finally, processed exosomes were utilized to treat APPswe-SH-SY5Y cells and decrease the expression of Aβ1−42 and BACE1 and further alleviated apoptosis. Conclusion HuMSCs-derived exosomes loaded with hsa-miR-29a via ExoNP to efficiently deliver to APPswe-SH-SY5Y cells and alleviate Aβ1−42 expression and promote cell survival.
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- 2022
23. One-Step Method for Material Quantitation Using In-Line Tomography With Single Scanning
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Suyu Liao, Shiwo Deng, Yining Zhu, Huitao Zhang, Peiping Zhu, Kai Zhang, and Xing Zhao
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Image and Video Processing (eess.IV) ,FOS: Electrical engineering, electronic engineering, information engineering ,Biomedical Engineering ,FOS: Physical sciences ,Medical Physics (physics.med-ph) ,Electrical Engineering and Systems Science - Image and Video Processing ,Physics - Medical Physics - Abstract
Objective: Quantitative technique based on In-line phase-contrast computed tomography with single scanning attracts more attention in application due to the flexibility of the implementation. However, the quantitative results usually suffer from artifacts and noise, since the phase retrieval and reconstruction are independent ("two-steps") without feedback from the original data. Our goal is to develop a method for material quantitative imaging based on a priori information specifically for the single-scanning data. Method: An iterative method that directly reconstructs the refractive index decrement delta and imaginary beta of the object from observed data ("one-step") within single object-to-detector distance (ODD) scanning. Simultaneously, high-quality quantitative reconstruction results are obtained by using a linear approximation that achieves material decomposition in the iterative process. Results: By comparing the equivalent atomic number of the material decomposition results in experiments, the accuracy of the proposed method is greater than 97.2%. Conclusion: The quantitative reconstruction and decomposition results are effectively improved, and there are feedback and corrections during the iteration, which effectively reduce the impact of noise and errors. Significance: This algorithm has the potential for quantitative imaging research, especially for imaging live samples and human breast preclinical studies.
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- 2022
24. The effect of bacteria inoculation on the lignocellulose degradation and the microbial properties during cow dung composting
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Liuyan Zhou, Xinping Yang, Yuqing Xie, Xiaowu Wang, Jinping Dai, Zhifang Wang, Huitao Zhang, and Lei Feng
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The goal of this work was to explore the potential effects of bacteria inoculation on the lignocellulose degradation and the underlying microbial mechanism during cow dung composting. The results suggested that bacteria inoculation better-accelerated temperature rose and increased thermophilic phase. Compared to the control (without inoculation, CK), the cellulose, hemicellulose, and lignin degradation rates of treated group (EG) increased from 53.3% to 70.0%, 50.2% to 61.3% and 46.4% to 60.0%, respectively. The microbial community structure and diversity were obviously changed by inoculation. Moreover, inoculation contributed to modulate the key compost microbial functional populations linking to the degradation of lignocelluloses by stamp analysis. Correlation matrix analysis indicated that the expression of bacterial lingo-cellulolytic enzymes were closely related to the key microbial functional populations. Overall, the results confirmed the importance of bacteria inoculation and have important implication for promoting the efficiency and quality of cow dung compost.
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- 2022
25. Multi-scale dilated dense reconstruction network for limited-angle computed tomography
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Haichuan Zhou, Yining Zhu, Huitao Zhang, Xing Zhao, and Peng Zhang
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Radiological and Ultrasound Technology ,Radiology, Nuclear Medicine and imaging - Abstract
Objective. Due to the incomplete projection data, the image reconstructed by limited-angle computed tomography (CT) usually suffers from significant artifacts, by which the structural details are heavily blurred. In this study, we aim to develop a novel approach to improve the limited-angle CT reconstruction performance, especially for the narrow scanning angular range. Approach. A deep learning based iterative framework for limited-angle tomography is proposed, which is named multi-scale dilated dense reconstruction network (MSDDRNet). The MSDDRNet utilizes a multi-scale dilated dense convolution neural network (MSDD-CNN) with conventional reconstruction algorithm for predicting image from incomplete projection data. The MSDD-CNN enhances the image features in the network by merging the DenseNet-Like structure, which serves to restore invisible singularities and reduce artifacts, as well as introducing constraints on the projection domain data into the iterative process to achieve better image detail recovery. Additionally, to improve the training speed of the network, we use a strategy of pre-training and model migration. Main results. Numerical experiments demonstrate that the proposed MSDDRNet performs well in terms of artifact correction, noise reduction and structure recovery compared to existing methods with limited scan angles, and we also extend the proposed method to more general scanning condition and other application such as dental CT data. Significance. The proposed method is a general framework, which can be applied to other CT problems, such as low dose CT, sparse-data CT and spectral CT.
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- 2023
26. Design of Anti-Lock Braking System for FSAE Racing Vehicle Based on New Slip Ratio Observation Method
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Yicai Liu, Da Wang, Luxu Liang, Huitao Zhang, Wenjie Wang, Mo Lv, Yiyang Wang, Yi Sun, and Shuai Yang
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- 2022
27. Projection-to-image transform frame: a lightweight block reconstruction network for computed tomography
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Genwei Ma, Xing Zhao, Yining Zhu, and Huitao Zhang
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Radiological and Ultrasound Technology ,Phantoms, Imaging ,Research Design ,Image Processing, Computer-Assisted ,ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION ,Radiology, Nuclear Medicine and imaging ,Neural Networks, Computer ,Radiation Dosage ,Tomography, X-Ray Computed ,Algorithms - Abstract
Several reconstruction networks have been invented to solve the problem of learning-based computed tomography (CT) reconstruction. However, the application of neural networks to tomographic reconstruction remains challenging due to unacceptable memory space requirements. In this study, we present a novel lightweight block reconstruction network (LBRN), which transforms the reconstruction operator into a deep neural network by unrolling the filter back-projection (FBP) method. Specifically, the proposed network contains two main modules, which respectively correspond to the filter and back-projection of the FBP method. The first module of the LBRN decouples the relationship of the Radon transform between the reconstructed image and the projection data. Therefore, the following module, block back-projection, can use the block reconstruction strategy. Because each image block is only connected with part-filtered projection data, the network structure is greatly simplified and the parameters of the whole network are dramatically reduced. Moreover, this approach is trained end-to-end, working directly from raw projection data, and does not depend on any initial images. Five reconstruction experiments are conducted to evaluate the performance of the proposed LBRN: full angle, low-dose CT, region of interest, metal artifact reduction and a real data experiment. The results of the experiments show that the LBRN can be effectively introduced into the reconstruction process and has outstanding advantages in terms of different reconstruction problems.
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- 2022
28. Understanding working conditions for Entererococcus sp. L1 on methane production: A low temperature condition-based biogas production experiment
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Wang Xiaou, Yang Xinping, Aihemati Guli, Wang Zhifang, Huitao Zhang, Jingping Dai, Xie Yuqing, Feng Lei, Jiang Li, and Jing Chen
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biology ,Strain (chemistry) ,Renewable Energy, Sustainability and the Environment ,Chemistry ,Forestry ,biology.organism_classification ,chemistry.chemical_compound ,Biogas ,Fermentation ,Food science ,Methane production ,Citric acid ,Waste Management and Disposal ,Agronomy and Crop Science ,Cow dung ,Bacteria ,Biogas production - Abstract
To provide an elaborate understanding on the performance of Entererococcus sp. L1 in biogas production at different fermentation periods under controlled low temperature, biogas optimization experiments was undertaken. Specifically, microscopic and culture techniques, physiological and biochemical studies, and measurement of optical densities at 600 wavelengths (OD600) were undertaken to identify and characterize the Entererococcus sp. L1. The aim was to identify the strain and determine its optimum working conditions in biogas production at different fermentation periods under controlled low temperature. The result confirmed the strain as hydrogen-producing bacteria (Enteroccus sp. L1). It was also confirmed that the organic nitrogen source was significantly better than the inorganic nitrogen source in supporting the growth of the bacteria. The optimal pH and temperature for the growth and biogas production performance of the Entererococcus sp. L1 was 7 and 15 °C respectively. The Na2HPO4 concentration of 0.2% was confirmed to be best for the optimum growth of the bacteria, and addition of citric acid resulted to significant inhibitory effect on the growth of the Entererococcus sp. L1. The effect of adding different concentrations (0, 1%, 5%, 10%) of the L1 bacteria inoculum on cow dung at simulated low temperature (15 °C) biogas fermentation showed that 10% treatment had the highest gas production of 3121 ml, which was 89% higher than the control (0 concentration). The daily gas production rate was 0.02 m3/(m−3d−1), which was 90% higher than the control. This showed that 10% treatment provided the best gas production result, with highest gas production occurring at 10% treatment within 31–60 days of fermentation (p
- Published
- 2021
29. Myocardial infarction biomarker C-reactive protein detection on nanocomposite aptasensor.
- Author
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Jing Li, Haitao Li, Jinpeng Xu, Xingzhou Zhao, Shujiang Song, and Huitao Zhang
- Subjects
C-reactive protein ,TROPONIN I ,BIOMARKERS ,MYOCARDIAL infarction ,NANOCOMPOSITE materials ,CARBON nanotubes - Abstract
Myocardial infarction (MI) is considered as one of the major life-threatening health issues worldwide. Growing number of cases every year is demanding rapid, portable, and early detection by the sensing devices for the identification of MI. This research work introduces a modified interdigitated electrode (IDE) sensing surface constructed with single-walled carbon nanotube (SWCN) to detect the cardiac biomarker, C-reactive protein (CRP). CRP-specific aptamer was conjugated with gold nanoparticle and attached on SWCN-constructed IDE surface. This probe-modified sensing surface has reached the limit of CRP detection to 10 pM on a linear regression curve with the regression coefficient of R² = 0.9223 [y = 0.9198x - 0.4326]. Further, control molecules, such as random aptamer sequence and nontarget cardiac biomarker (Troponin I), did not show the current response, indicating the specific CRP detection. This sensing strategy helps to detect the lower level of CRP and diagnose the MI at its earlier stages. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
30. Think of Several Issues on Precision Guided Weapons Intelligentizing
- Author
-
Fan Huitao, Zhang Xinchao
- Subjects
precision guided weapons ,artificial intelligence ,transfer learning ,the combination of intuition and rationality ,Motor vehicles. Aeronautics. Astronautics ,TL1-4050 - Abstract
This article introduces the role of artificial intelligence technology in advancing the intlelligence of precision Guided weapons, outlines the current status of intelligence in it’s detection and recognizing, guidance and control. It discusses the problems faced during the intelligentization process, such as the construction of large samples, transferring simulation performance to real-world capabilities, issues with interptetability and reliability, and the assessment of intelligent weapon performance. Targeted solutions are pesented, including hardware-in-the-loop simulation training, transfer learning, combining human intuition with rationality, and reconstructiong evaluation methods. Three impacts of intelligent precision guided weapons on equipment development and operational use were proposed: increasing importance of simulation technology, significant changed in training patterns, and existing conmbat modes will be overturned.
- Published
- 2024
- Full Text
- View/download PDF
31. Intelligent Classification and Characteristics of Missile Weaponry
- Author
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Fan Huitao, Zhang Tonghe, Zhang Liang
- Subjects
intelligence ,missile ,intelligent classification ,intelligent feature ,weaponry ,Motor vehicles. Aeronautics. Astronautics ,TL1-4050 - Abstract
This paper discusses the intelligent classification and characteristics of missile weaponry, and defines the concept and connotation of intelligent missile. Based on the principle of algorithm design and the development characteristics of missile weaponry, the intelligent level of missile is divided into four levels, that are the initial level, the medium level, the high level and the super level, and the internal meaning of each level is expounded. This paper focuses on the intelligent characteristics of missile weaponry, and describes the capability performance of four levels of intelligent missiles, also discusses the key development technologies of intelligent missile, and introduces the research focus of various key technologies at the current stage based on the current technical status.
- Published
- 2022
- Full Text
- View/download PDF
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