153 results on '"Grimsgaard AS"'
Search Results
2. Drinking alcohol in moderation is associated with lower rate of all-cause mortality in individuals with higher rather than lower educational level: findings from the MORGAM project
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Di Castelnuovo, Augusto, Bonaccio, Marialaura, Costanzo, Simona, McElduff, Patrick, Linneberg, Allen, Salomaa, Veikko, Männistö, Satu, Ferrières, Jean, Dallongeville, Jean, Thorand, Barbara, Brenner, Hermann, Ferrario, Marco, Veronesi, Giovanni, Tamosiunas, Abdonas, Grimsgaard, Sameline, Drygas, Wojciech, Malyutina, Sofia, Söderberg, Stefan, Nordendahl, Maria, Kee, Frank, Grassi, Guido, Dabboura, Salim, Borchini, Rossana, Westermann, Dirk, Schrage, Benedikt, Zeller, Tanja, Kuulasmaa, Kari, Blankenberg, Stefan, Donati, Maria Benedetta, Iacoviello, Licia, and de Gaetano, Giovanni
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- 2023
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3. Comparing associations of handgrip strength and chair stand performance with all-cause mortality—implications for defining probable sarcopenia: the Tromsø Study 2015–2020
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Jonas Johansson, Sameline Grimsgaard, Bjørn Heine Strand, Avan A. Sayer, and Rachel Cooper
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Handgrip strength ,Chair stand performance ,All-cause mortality ,Sarcopenia ,Medicine - Abstract
Abstract Background Widely adopted criteria suggest using either low handgrip strength or poor chair stand performance to identify probable sarcopenia. However, there are limited direct comparisons of these measures in relation to important clinical endpoints. We aimed to compare associations between these two measures of probable sarcopenia and all-cause mortality. Methods Analyses included 7838 community-dwelling participants (55% women) aged 40–84 years from the seventh survey of the Tromsø Study (2015–2016), with handgrip strength assessed using a Jamar + Digital Dynamometer and a five-repetition chair stand test (5-CST) also undertaken. We generated sex-specific T-scores and categorised these as “not low”, “low”, and “very low” handgrip strength or 5-CST performance. Cox Proportional Hazard regression models were used to investigate associations between these two categorised performance scores and time to death (up to November 2020 ascertained from the Norwegian Cause of Death registry), adjusted for potential confounders including lifestyle factors and specific diseases. Results A total of 233 deaths occurred (median follow-up 4.7 years) with 1- and 5-year mortality rates at 3.1 (95% confidence interval [CI] 2.1, 4.6) and 6.3 (95% CI 5.5, 7.2) per 1000 person-years, respectively. There was poor agreement between the handgrip strength and 5-CST categories for men (Cohen’s kappa [κ] = 0.19) or women (κ = 0.20). Fully adjusted models including handgrip strength and 5-CST performance mutually adjusted for each other, showed higher mortality rates among participants with low (hazard ratio [HR] 1.22, 95% CI 0.87, 1.71) and very low (HR 1.68, 95% CI 1.02, 2.75) handgrip strength compared with the not low category. Similar associations, although stronger, were seen for low (HR 1.88, 95% CI 1.38, 2.56) and very low (HR 2.64, 95% CI 1.73, 4.03) 5-CST performance compared with the not low category. Conclusions We found poor agreement between T-score categories for handgrip strength and 5-CST performance and independent associations with mortality. Our findings suggest that these tests identify different people at risk when case-finding probable sarcopenia. As discussions on an international consensus for sarcopenia definitions proceed, testing both handgrip strength and chair stand performance should be recommended rather than viewing these as interchangeable assessments.
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- 2023
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4. Comparing associations of handgrip strength and chair stand performance with all-cause mortality—implications for defining probable sarcopenia: the Tromsø Study 2015–2020
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Johansson, Jonas, Grimsgaard, Sameline, Strand, Bjørn Heine, Sayer, Avan A., and Cooper, Rachel
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- 2023
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5. Patient and public involvement in health research in Norway: a survey among researchers and patient organisations
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Aas, Sigve Nyvik, Distefano, Marita Borg, Pettersen, Ingvild, Gravrok, Berit, Nordvoll, Laila Yvonne, Bjaastad, Jon Fauskanger, and Grimsgaard, Sameline
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- 2023
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6. Social inequality in prevalence of NCD risk factors: a cross-sectional analysis from the population-based Tromsø Study 2015–2016
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Bjarne K Jacobsen, Jonas Johansson, Tom Wilsgaard, Laila Arnesdatter Hopstock, Sameline Grimsgaard, Inger Ariansen, and Rebecca A Hetland
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Medicine - Abstract
Objective We aimed to examine associations between educational level, serving as an indicator of socioeconomic position, and prevalence of WHO-established leading behavioural and biological risk factors for non-communicable diseases (NCDs), in middle-aged to older women and men.Design Population-based cross-sectional study.Setting All inhabitants of the municipality of Tromsø, Norway, aged ≥40 years, were invited to the seventh survey (2015–2016) of the Tromsø Study; an ongoing population-based cohort study.Participants Of the 32 591 invited; 65% attended, and a total of 21 069 women (53%) and men aged 40–99 years were included in our study.Outcome measures We assessed associations between educational level and NCD behavioural and biological risk factors: daily smoking, physical inactivity (sedentary in leisure time), insufficient fruit/vegetable intake (10 g/day in women, >20 g/day in men), hypertension, obesity, intermediate hyperglycaemia and hypercholesterolaemia. These were expressed as odds ratios (OR) per unit decrease in educational level, with 95% CIs, in women and men.Results In women (results were not significantly different in men), we observed statistically significant associations between lower educational levels and higher odds of daily smoking (OR 1.69; 95% CI 1.60 to 1.78), physical inactivity (OR 1.38; 95% CI 1.31 to 1.46), insufficient fruit/vegetable intake (OR 1.54, 95% CI 1.43 to 1.66), hypertension (OR 1.25; 95% CI 1.20 to 1.30), obesity (OR 1.23; 95% CI 1.18 to 1.29), intermediate hyperglycaemia (OR 1.12; 95% CI 1.06 to 1.19), and hypercholesterolaemia (OR 1.07; 95% CI 1.03 to 1.12), and lower odds of harmful alcohol use (OR 0.75; 95% CI 0.72 to 0.78).Conclusion We found statistically significant educational gradients in women and men for all WHO-established leading NCD risk factors within a Nordic middle-aged to older general population. The prevalence of all risk factors increased at lower educational levels, except for harmful alcohol use, which increased at higher educational levels.
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- 2024
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7. Educational patterning in biological health seven years apart: Findings from the Tromsø Study
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Neufcourt, Lola, Castagné, Raphaële, Wilsgaard, Tom, Grimsgaard, Sameline, Chadeau-Hyam, Marc, Vuckovic, Dragana, Ugarteche-Perez, Ainhoa, Farbu, Erlend Hoftun, Sandanger, Torkjel M., Delpierre, Cyrille, and Kelly-Irving, Michelle
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- 2024
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8. Patient and public involvement in health research in Norway: a survey among researchers and patient organisations
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Sigve Nyvik Aas, Marita Borg Distefano, Ingvild Pettersen, Berit Gravrok, Laila Yvonne Nordvoll, Jon Fauskanger Bjaastad, and Sameline Grimsgaard
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Patient and public involvement ,User representatives ,Health research ,Medicine ,Medicine (General) ,R5-920 - Abstract
Abstract Background Patient and public involvement (PPI) in health research may improve both the relevance and quality of the research. There is however a lack of research investigating the experiences, attitudes and barriers towards PPI in clinical research in Norway. The Norwegian Clinical Research Infrastructure Network therefore conducted a survey among researchers and PPI contributors aiming to investigate experiences with PPI and identify current challenges for successful involvement. Methods Two survey questionnaires were developed and distributed in October and November 2021. The survey targeting 1185 researchers was distributed from the research administrative system in the Regional Health Trusts. The survey targeting PPI contributors was distributed through Norwegian patient organisations, regional and national competence centers. Results The response rate was 30% among researchers and was unobtainable from PPI contributors due to the survey distribution strategy. PPI was most frequently used in the planning and conduct of the studies, and less utilized in dissemination and implementation of results. Both researchers and user representatives were generally positive to PPI, and agreed that PPI might be more useful in clinical research than in underpinning research. Researchers and PPI contributors who reported that roles and expectations were clarified in advance, were more likely to experience a common understanding of roles and responsibilities in the research project. Both groups pointed to the importance of earmarked funding for PPI activities. There was a demand for a closer collaboration between researchers and patient organisations to develop accessible tools and effective models for PPI in health research. Conclusions Surveys among clinical researchers and PPI contributors indicate overall positive attitudes towards PPI in clinical research. However, more resources, such as budget, time, and accessible tools, are needed. Clarifying roles and expectations, and creating new PPI models under resource constraints can enhance its effectiveness. PPI is underutilized in disseminating and implementing research results, presenting an opportunity for improving healthcare outcomes.
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- 2023
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9. Life expectancy associated with different ages at diagnosis of type 2 diabetes in high-income countries: 23 million person-years of observation
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Kaptoge, S, Seshasai, SRK, Sun, L, Walker, M, Bolton, T, Spackman, S, Ataklte, F, Willeit, P, Bell, S, Burgess, S, Pennells, L, Altay, S, Assmann, G, Ben-Shlomo, Y, Best, LG, Björkelund, C, Blazer, DG, Brenner, H, Brunner, EJ, Dagenais, GR, Cooper, JA, Cooper, C, Crespo, CJ, Cushman, M, D'Agostino, RB, Sr, Daimon, M, Daniels, LB, Danker, R, Davidson, KW, de Jongh, RT, Donfrancesco, C, Ducimetiere, P, Elders, PJM, Engström, G, Ford, I, Gallacher, I, Bakker, SJL, Goldbourt, U, de La Cámara, G, Grimsgaard, S, Gudnason, V, Hansson, PO, Imano, H, Jukema, JW, Kabrhel, C, Kauhanen, J, Kavousi, M, Kiechl, S, Knuiman, MW, Kromhout, D, Krumholz, HM, Kuller, LH, Laatikainen, T, Lowler, DA, Meyer, HE, Mukamal, K, Nietert, PJ, Ninomiya, T, Nitsch, D, Nordestgaard, BG, Palmieri, L, Price, JF, Ridker, PM, Sun, Q, Rosengren, A, Roussel, R, Sakurai, M, Salomaa, V, Schöttker, B, Shaw, JE, Strandberg, TE, Sundström, J, Tolonen, H, Tverdal, A, Verschuren, WMM, Völzke, H, Wagenknecht, L, Wallace, RB, Wannamethee, SG, Wareham, NJ, Wassertheil-Smoller, S, Yamagishi, K, Yeap, BB, Harrison, S, Inouye, M, Griffin, S, Butterworth, AS, Wood, AM, Thompson, SG, Sattar, N, Danesh, J, Di Angelantonio, E, Tipping, RW, Russell, S, Johansen, M, Bancks, MP, Mongraw-Chaffin, M, Magliano, D, Barr, ELM, Zimmet, PZ, Whincup, PH, Willeit, J, Leitner, C, Lawlor, DA, Elwood, P, Sutherland, SE, Hunt, KJ, Selmer, RM, Haheim, LL, Ariansen, I, Tybjaer-Hansen, A, Frikkle-Schmidt, R, Langsted, A, Lo Noce, C, Balkau, B, Bonnet, F, Fumeron, F, Pablos, DL, Ferro, CR, Morales, TG, Mclachlan, S, Guralnik, J, Khaw, KT, Holleczek, B, Stocker, H, Nissinen, A, Vartiainen, E, Jousilahti, P, Harald, K, Massaro, JM, Pencina, M, Lyass, A, Susa, S, Oizumi, T, Kayama, T, Chetrit, A, Roth, J, Orenstein, L, Welin, L, Svärdsudd, K, Lissner, L, Hange, D, Mehlig, K, Tilvis, RS, Dennison, E, Westbury, L, Norman, PE, Almeida, OP, Hankey, GJ, Hata, J, Shibata, M, Furuta, Y, Bom, MT, Rutters, F, Muilwijk, M, Kraft, P, Lindstrom, S, Turman, C, Kiyama, M, Kitamura, A, Gerber, Y, Salonen, JT, van Schoor, LN, van Zutphen, EM, Melander, O, Psaty, BM, Blaha, M, de Boer, IH, Kronmal, RA, Grandits, G, Shin, H-C, Albertorio, JR, Gillum, RF, Hu, FB, Humphries, S, Hill- Briggs, F, Vrany, E, Butler, M, Schwartz, JE, Iso, H, Amouyel, P, Arveiler, D, Ferrieres, J, Gansevoort, RT, de Boer, R, Kieneker, L, Trompet, S, Kearney, P, Cantin, B, Després, JP, Lamarche, B, Laughlin, G, McEvoy, L, Aspelund, T, Thorsson, B, Sigurdsson, G, Tilly, M, Ikram, MA, Dorr, M, Schipf, S, Fretts, AM, Umans, JG, Ali, T, Shara, N, Davey-Smith, G, Can, G, Yüksel, H, Özkan, U, Nakagawa, H, Morikawa, Y, Ishizaki, M, Njølstad, I, Wilsgaard, T, Mathiesen, E, Buring, J, Cook, N, Arndt, V, Rothenbacher, D, Manson, J, Tinker, L, Shipley, M, Tabak, AG, Kivimaki, M, Packard, C, Robertson, M, Feskens, E, and Geleijnse, M
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- 2023
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10. Lipid Levels During Adult Lifetime in Men and Women With and Without a Subsequent Incident Myocardial Infarction: A Longitudinal Analysis of Data From the Tromsø Study 1974 to 2016
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Grethe Albrektsen, Tom Wilsgaard, Ivar Heuch, Maja‐Lisa Løchen, Dag Steinar Thelle, Inger Njølstad, Sameline Grimsgaard, and Kaare Harald Bønaa
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incident myocardial infarction ,lipid profile ,longitudinal study ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Background The atherosclerotic effect of an adverse lipid profile is assumed to accumulate throughout life, leading to increased risk of myocardial infarction (MI). Still, little is known about age at onset and duration of unfavorable lipid levels before MI. Methods and Results Longitudinal data on serum lipid levels for 26 130 individuals (50.5% women, aged 20–89 years) were obtained from 7 population‐based health surveys in Tromsø, Norway. Diagnoses of MI were obtained from national registers. A linear mixed model was applied to compare age‐ and sex‐specific mean values of total cholesterol, high‐density lipoprotein cholesterol (HDL‐C), and triglyceride concentration by MI status (MI versus non‐MI). Already from young adulthood, 20 to 35 years before the incident MI, individuals with a subsequent incident MI had on average more adverse lipid levels than individuals of the same age and sex without MI. Analogous to a dose–response relationship, there was a clear trend toward more severe adverse lipid levels the lower the age at incident MI (P
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- 2023
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11. Associations between postprandial triglyceride concentrations and sex, age, and body mass index: cross-sectional analyses from the Tromsø study 2015–2016
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Mari Mikkelsen, Tom Wilsgaard, Sameline Grimsgaard, Laila A. Hopstock, and Patrik Hansson
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lipids ,non-fasting triglycerides ,postprandial period ,time since last meal ,sex ,age ,Nutrition. Foods and food supply ,TX341-641 - Abstract
IntroductionElevated serum triglyceride concentrations increase the risk of developing atherosclerosis, the leading cause of cardiovascular disease. Postprandial triglyceride concentrations have shown to be a stronger predictor of cardiovascular disease compared to fasting triglycerides. It is therefore clinically relevant to study patterns of postprandial triglyceride concentrations in a general adult population.AimsThe aim of this cross-sectional analysis was to examine postprandial triglyceride concentrations in women and men, and the association with age, body mass index and menopausal status.MethodsNon-fasting blood samples from 20,963 women and men aged 40 years and older, attending the seventh survey of the Tromsø Study (2015–2016), were analyzed for postprandial triglyceride concentrations using descriptive statistics and linear regression models. Self-reported time since last meal before blood sampling was categorized into 1-h intervals with 7+ hours considered fasting.ResultsMen had higher triglyceride concentrations compared to women. The pattern of postprandial triglyceride concentrations differed between the sexes. In women, the highest triglyceride concentration (19% higher compared to fasting level, p < 0.001) was found 3–4 h postprandially compared to 1–3 h in men (30% higher compared to fasting level, p < 0.001). In women, all subgroups of age and BMI had higher triglyceride concentrations than the reference group (age 40–49 years and BMI < 25 kg/m2), but no linear trend for age was observed. In men, triglyceride concentrations were inversely associated with age. Body mass index was positively associated with triglyceride concentration in both women (p < 0.001) and men (p < 0.001), although this association was somewhat modified by age in women. Postmenopausal women had significantly higher triglyceride concentrations compared to premenopausal women (p < 0.05).ConclusionPostprandial triglyceride concentrations differed in groups of sex, age, body mass index, and menopausal status.
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- 2023
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12. Management
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Grimsgaard, Wanda, primary
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- 2022
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13. Design
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Grimsgaard, Wanda, primary
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- 2022
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14. Strategy
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Grimsgaard, Wanda, primary
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- 2022
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15. Insight
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Grimsgaard, Wanda, primary
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- 2022
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16. Production
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Grimsgaard, Wanda, primary
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- 2022
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17. Lifestyle factors as mediators of area-level socio-economic differentials in cardiovascular disease risk factors. The Tromsø Study
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Tiwari, Sweta, Cerin, Ester, Wilsgaard, Tom, Løvsletten, Ola, Njølstad, Inger, Grimsgaard, Sameline, Hopstock, Laila A., Schirmer, Henrik, Rosengren, Annika, Kristoffersen, Kathrine, and Løchen, Maja-Lisa
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- 2022
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18. Dataset of fitness trackers and smartwatches to measuring physical activity in research
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Henriksen, André, Woldaregay, Ashenafi Zebene, Muzny, Miroslav, Hartvigsen, Gunnar, Hopstock, Laila Arnesdatter, and Grimsgaard, Sameline
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- 2022
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19. Simple cardiovascular risk stratification by replacing total serum cholesterol with anthropometric measures: The MORGAM prospective cohort project
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Rosberg, Victoria, Vishram-Nielsen, Julie KK, Kristensen, Anna M. Dyrvig, Pareek, Manan, Sehested, Thomas S.G., Nilsson, Peter M, Linneberg, Allan, Palmieri, Luigi, Giampaoli, Simona, Donfrancesco, Chiara, Kee, Frank, Mancia, Giuseppe, Cesana, Giancarlo, Veronesi, Giovanni, Grassi, Guido, Kuulasmaa, Kari, Salomaa, Veikko, Palosaari, Tarja, Sans, Susana, Ferrieres, Jean, Dallongeville, Jean, Söderberg, Stefan, Moitry, Marie, Drygas, Wojciech, Tamosiunas, Abdonas, Peters, Annette, Brenner, Hermann, Schöttker, Ben, Grimsgaard, Sameline, Biering-Sørensen, Tor, and Olsen, Michael H
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- 2022
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20. Advancing a new model of collaborative practice: a decade of Whole Health interprofessional education across Veterans Health Administration.
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Liao, Theresa H., Rindfleisch, J. Adam, Howard, Kelly Peyton, Castellani, Marc, and Noyes, Sara Grimsgaard
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VETERANS' health ,INTERPROFESSIONAL education ,TRANSFORMATIVE learning ,INTEGRATIVE medicine ,MEDICAL care - Abstract
Large-scale implementation of interprofessional education across the United States Veterans Health Administration has supported advancement of a new model of collaborative practice, the Whole Health System, centering on the patient and what matters most to them. Other health care systems can consider similar educational efforts for health care transformation. [ABSTRACT FROM AUTHOR]
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- 2024
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21. Dataset of fitness trackers and smartwatches to measuring physical activity in research
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André Henriksen, Ashenafi Zebene Woldaregay, Miroslav Muzny, Gunnar Hartvigsen, Laila Arnesdatter Hopstock, and Sameline Grimsgaard
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Motor activity ,Activity tracker ,Smart watch ,Heart rate ,Photoplethysmography ,Wearables ,Medicine ,Biology (General) ,QH301-705.5 ,Science (General) ,Q1-390 - Abstract
Abstract Objectives Accelerometer-based wrist-worn fitness trackers and smartwatches (wearables) appeared on the consumer market in 2011. Many wearable devices have been released since. The objective of this data paper is to describe a dataset of 423 wearables released before July 2017. Data description We identified wearables and extracted information from six online and offline databases. We also visited websites for all identified companies/brands to identify additional wearables, as well as obtained additional information for each identified device. Twelve attributes were collected: wearable name, company/brand name, release year, country of origin, whether the wearable was crowd funded, form factor (fitness tracker or smartwatch), and sensors supported. Support for the following sensors were mapped: accelerometer, magnetometer, gyroscope, altimeter or barometer, global-positioning-system, and optical pulse sensor (i.e., photoplethysmograph). The search was conducted between May 15th and July 1st, 2017. The included data gives an overview of most in-scope wearables released before July 2017 and allows researchers to conduct additional analysis not performed in the related article. Further insights can be achieved by complementing this list with wearable models released after July 2017.
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- 2022
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22. Social inequality in prevalence of NCD risk factors: a cross-sectional analysis from the population-based Tromsø Study 2015–2016
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Hetland, Rebecca A, primary, Wilsgaard, Tom, additional, Hopstock, Laila Arnesdatter, additional, Ariansen, Inger, additional, Johansson, Jonas, additional, Jacobsen, Bjarne K, additional, and Grimsgaard, Sameline, additional
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- 2024
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23. Anthropometric measures are satisfactory substitutes for the DXA‐derived visceral adipose tissue in the association with cardiometabolic risk—The Tromsø Study 2015–2016
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Marie W. Lundblad, Bjarne K. Jacobsen, Jonas Johansson, Sameline Grimsgaard, Lene F. Andersen, and Laila A. Hopstock
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cardiometabolic health ,dual energy x‐ray absorptiometry ,obesity ,overweight ,population studies ,visceral adipose tissue ,Internal medicine ,RC31-1245 - Abstract
Abstract Background Body mass index (BMI) increases while cardiometabolic risk factors decrease in individuals in high‐income countries. This paradoxical observation raises the question of whether current measures of overweight and obesity properly identify cardiometabolic risk. Methods A total of 3675 participants (59% women) aged 40–84 years with whole‐body dual‐energy x‐ray absorptiometry scans from the seventh survey of the Tromsø Study were included to examine the association between visceral adipose tissue (VAT) in grams and BMI, waist circumference (WC), waist‐to‐hip ratio (WHR), and waist‐to‐height ratio (WHtR). Further, their association with single cardiometabolic risk factors (blood pressure, triglycerides, total cholesterol, high‐density lipoprotein [HDL] cholesterol, glycated hemoglobin, high‐sensitivity C‐reactive protein), modified single components from the ATP Ⅲ criteria for metabolic syndrome (hypertension, diabetes, high triglycerides, and low HDL cholesterol), and metabolic syndrome were examined. Results VAT mass was strongly correlated with BMI (r ≥ 0.77), WC (r ≥ 0.80), WHR (r ≥ 0.58), and WHtR (r ≥ 0.78). WC was the strongest predictor for VAT (area under the curve: 0.90). Compared to anthropometric measures, the associations between VAT and metabolic syndrome as well as single components of metabolic syndrome were statistically significantly stronger, but the clinical differences were likely minor. Conclusion Although VAT mass showed statistically stronger associations with cardiometabolic risk compared to traditional anthropometrics, the clinical importance was likely small. Simple, clinically available tools seem to satisfactory substitute for VAT to identify cardiometabolic risk.
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- 2021
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24. Complex lifestyle intervention among inactive older adults with elevated cardiovascular disease risk and obesity: a mixed-method, single-arm feasibility study for RESTART—a randomized controlled trial
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Trygve S. Deraas, Laila Hopstock, Andre Henriksen, Bente Morseth, Anne Sofie Sand, Inger Njølstad, Sigurd Pedersen, Edvard Sagelv, Jonas Johansson, and Sameline Grimsgaard
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Feasibility study ,Older adults ,Lifestyle intervention ,Primary prevention ,Cardiovascular disease risk ,Obesity ,Medicine (General) ,R5-920 - Abstract
Abstract Background Physical inactivity and obesity are global public health challenges. Older adults are important to target for prevention and management of disease and chronic conditions. However, many individuals struggle with maintaining increased physical activity (PA) and improved diet. This feasibility study provides the foundation for the RESTART trial, a randomized controlled trial (RCT) to test a complex intervention to facilitate favourable lifestyle changes older adults can sustain. The primary objective of this study was to investigate study feasibility (recruitment, adherence, side-effects, and logistics) using an interdisciplinary approach. Methods This 1-year prospective mixed-method single-arm feasibility study was conducted in Tromsø, Norway, from September 2017. We invited by mail randomly selected participants from the seventh survey of the Tromsø Study (2015–2016) aged 55–75 years with sedentary lifestyle, obesity, and elevated cardiovascular risk. Participants attended a 6-month complex lifestyle intervention program, comprising instructor-led high-intensive exercise and nutritionist- and psychologist-led counselling, followed by a 6-month follow-up. All participants used a Polar activity tracker for daily activity monitoring during the intervention. Participants were interviewed three times throughout the study. Primary outcome was study feasibility measures. Results We invited potential participants (n=75) by mail of which 27 % (n=20) agreed to participate. Telephone screening excluded four participants, and altogether 16 participants completed baseline screening. The intervention and test procedures of primary and secondary outcomes were feasible and acceptable for the participants. There were no exercise-induced injuries, indicating that the intervention program is safe. Participants experienced that the dietary and psychological counselling were delivered too early in the intervention and in too close proximity to the start of the exercise program. Minor logistic improvements were implemented throughout the intervention period. Conclusion This study indicates that it is feasible to conduct a full-scale RCT of a multi-component randomized intervention trial, based on the model of the present study. No dropouts due to exercise-induced injury indicates that the exercises were safe. While minor improvements in logistics were implemented during the intervention, we will improve recruitment and adherence strategies, rearrange schedule of intervention contents (exercise, diet, and psychology), as well as improve the content of the dietary and behavioural counselling to maximize outcome effects in the RESTART protocol. Trial registration ClinicalTrials.gov Identifier: NCT03807323 Registered 16 January 2019 – retrospectively registered.
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- 2021
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25. Lifestyle factors as mediators of area-level socio-economic differentials in cardiovascular disease risk factors. The Tromsø Study
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Sweta Tiwari, Ester Cerin, Tom Wilsgaard, Ola Løvsletten, Inger Njølstad, Sameline Grimsgaard, Laila A. Hopstock, Henrik Schirmer, Annika Rosengren, Kathrine Kristoffersen, and Maja-Lisa Løchen
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Area level socio-economic status ,Cardiovascular disease ,Risk factors ,Mediation ,Public aspects of medicine ,RA1-1270 ,Social sciences (General) ,H1-99 - Abstract
Introduction: Cardiovascular disease (CVD) is a leading cause of death and disability and living in areas with low socio-economic status (SES) is associated with increased risk of CVD. Lifestyle factors such as smoking, physical inactivity, an unhealthy diet and harmful alcohol use are main risk factors that contribute to other modifiable risk factors, such as hypertension, raised blood cholesterol, obesity, and diabetes. The potential impact of area-level socio-economic status (ASES) on metabolic CVD risk factors via lifestyle behaviors independent of individual SES has not been investigated previously. Aims: To estimate associations of ASES with CVD risk factors and the mediating role of lifestyle behaviors independent of individual-level SES. Methods: In this cross-sectional study, we included 19,415 participants (52% women) from the seventh survey of the Tromsø Study (2015–2016) (Tromsø7). The exposure variable ASES was created by aggregating individual-level SES variables (education, income, housing ownership) at the geographical subdivision level. Individual-level SES data and geographical subdivision of Tromsø municipality (36 areas) were obtained from Statistics Norway. Variables from questionnaires and clinical examinations obtained from Tromsø7 were used as mediators (smoking, snuff, alcohol, and physical activity), while the outcome variables were body mass index (BMI), total/high-density lipoprotein (HDL) cholesterol ratio, waist circumference, hypertension, diabetes. Mediation and mediated moderation analysis were performed with age as a moderator, stratified by sex. Results: ASES was significantly associated with all outcome variables. CVD risk factor level declined with an increase in ASES. These associations were mediated by differences in smoking habits, alcohol use and physical activity. The associations of ASES with total/HDL cholesterol ratio and waist circumference (women) were moderated by age, and the moderating effects were mediated by smoking and physical activity in both sexes. The largest mediated effects were seen in the associations of ASES with total/HDL cholesterol ratio, with the mediators accounting for 43% of the observed effects. Conclusions: Living in lower SES areas is associated with increased CVD risk due to unhealthy lifestyle behaviors, such as smoking, alcohol use and physical inactivity. These associations were stronger in women and among older participants.
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- 2022
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26. Barns deltakelse som en vilje til ikke å la seg styre
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Grimsgaard, Cathrine, primary
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- 2022
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27. Regional and temporal differences in the associations between cardiovascular disease and its classic risk factors: an analysis of 49 cohorts from 11 European countries
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Reinikainen, J, Kuulasmaa, K, Oskarsson, V, Amouyel, P, Biasch, K, Brenner, H, De Ponti, R, Donfrancesco, C, Drygas, W, Ferrieres, J, Grassi, G, Grimsgaard, S, Iacoviello, L, Jousilahti, P, Kårhus, L, Kee, F, Linneberg, A, Luksiene, D, Mariño, J, Moitry, M, Palmieri, L, Peters, A, Piwonska, A, Quarti-Trevano, F, Salomaa, V, Sans, S, Schmidt, C, Schöttker, B, Söderberg, S, Tamosiunas, A, Thorand, B, Tunstall-Pedoe, H, Vanuzzo, D, Veronesi, G, Woodward, M, Lekadir, K, Niiranen, T, Kårhus, LL, Schmidt, CO, Reinikainen, J, Kuulasmaa, K, Oskarsson, V, Amouyel, P, Biasch, K, Brenner, H, De Ponti, R, Donfrancesco, C, Drygas, W, Ferrieres, J, Grassi, G, Grimsgaard, S, Iacoviello, L, Jousilahti, P, Kårhus, L, Kee, F, Linneberg, A, Luksiene, D, Mariño, J, Moitry, M, Palmieri, L, Peters, A, Piwonska, A, Quarti-Trevano, F, Salomaa, V, Sans, S, Schmidt, C, Schöttker, B, Söderberg, S, Tamosiunas, A, Thorand, B, Tunstall-Pedoe, H, Vanuzzo, D, Veronesi, G, Woodward, M, Lekadir, K, Niiranen, T, Kårhus, LL, and Schmidt, CO
- Abstract
Aims: The regional and temporal differences in the associations between cardiovascular disease (CVD) and its classic risk factors are unknown. The current study examined these associations in different European regions over a 30-year period. Methods and results: The study sample comprised 553 818 individuals from 49 cohorts in 11 European countries (baseline: 1982-2012) who were followed up for a maximum of 10 years. Risk factors [sex, smoking, diabetes, non-HDL cholesterol, systolic blood pressure (BP), and body mass index (BMI)] and CVD events (coronary heart disease or stroke) were harmonized across cohorts. Risk factor-outcome associations were analysed using multivariable-adjusted Cox regression models, and differences in associations were assessed using meta-regression. The differences in the risk factor-CVD associations between central Europe, northern Europe, southern Europe, and the UK were generally small. Men had a slightly higher hazard ratio (HR) in southern Europe (P = 0.043 for overall difference), and those with diabetes had a slightly lower HR in central Europe (P = 0.022 for overall difference) compared with the other regions. Of the six CVD risk factors, minor HR decreases per decade were observed for non-HDL cholesterol [7% per mmol/L; 95% confidence interval (CI), 3-10%] and systolic BP (4% per 20 mmHg; 95% CI, 1-8%), while a minor HR increase per decade was observed for BMI (7% per 10 kg/m2; 95% CI, 1-13%). Conclusion: The results demonstrate that all classic CVD risk factors are still relevant in Europe, irrespective of regional area. Preventive strategies should focus on risk factors with the greatest population attributable risk.
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- 2024
28. Regional and temporal differences in the associations between cardiovascular disease and its classic risk factors:an analysis of 49 cohorts from 11 European countries
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Reinikainen, Jaakko, Kuulasmaa, Kari, Oskarsson, Viktor, Amouyel, Philippe, Biasch, Katia, Brenner, Hermann, De Ponti, Roberto, Donfrancesco, Chiara, Drygas, Wojciech, Ferrieres, Jean, Grassi, Guido, Grimsgaard, Sameline, Iacoviello, Licia, Jousilahti, Pekka, Kårhus, Line L, Kee, Frank, Linneberg, Allan, Luksiene, Dalia, Mariño, Joany, Moitry, Marie, Palmieri, Luigi, Peters, Annette, Piwonska, Aleksandra, Quarti-Trevano, Fosca, Salomaa, Veikko, Sans, Susana, Schmidt, Carsten Oliver, Schöttker, Ben, Söderberg, Stefan, Tamosiunas, Abdonas, Thorand, Barbara, Tunstall-Pedoe, Hugh, Vanuzzo, Diego, Veronesi, Giovanni, Woodward, Mark, Lekadir, Karim, Niiranen, Teemu, Reinikainen, Jaakko, Kuulasmaa, Kari, Oskarsson, Viktor, Amouyel, Philippe, Biasch, Katia, Brenner, Hermann, De Ponti, Roberto, Donfrancesco, Chiara, Drygas, Wojciech, Ferrieres, Jean, Grassi, Guido, Grimsgaard, Sameline, Iacoviello, Licia, Jousilahti, Pekka, Kårhus, Line L, Kee, Frank, Linneberg, Allan, Luksiene, Dalia, Mariño, Joany, Moitry, Marie, Palmieri, Luigi, Peters, Annette, Piwonska, Aleksandra, Quarti-Trevano, Fosca, Salomaa, Veikko, Sans, Susana, Schmidt, Carsten Oliver, Schöttker, Ben, Söderberg, Stefan, Tamosiunas, Abdonas, Thorand, Barbara, Tunstall-Pedoe, Hugh, Vanuzzo, Diego, Veronesi, Giovanni, Woodward, Mark, Lekadir, Karim, and Niiranen, Teemu
- Abstract
Aims The regional and temporal differences in the associations between cardiovascular disease (CVD) and its classic risk factors are unknown. The current study examined these associations in different European regions over a 30-year period. Methods and results The study sample comprised 553 818 individuals from 49 cohorts in 11 European countries (baseline: 1982–2012) who were followed up for a maximum of 10 years. Risk factors [sex, smoking, diabetes, non-HDL cholesterol, systolic blood pressure (BP), and body mass index (BMI)] and CVD events (coronary heart disease or stroke) were harmonized across cohorts. Risk factor–outcome associations were analysed using multivariable-adjusted Cox regression models, and differences in associations were assessed using meta-regression. The differences in the risk factor–CVD associations between central Europe, northern Europe, southern Europe, and the UK were generally small. Men had a slightly higher hazard ratio (HR) in southern Europe (P = 0.043 for overall difference), and those with diabetes had a slightly lower HR in central Europe (P = 0.022 for overall difference) compared with the other regions. Of the six CVD risk factors, minor HR decreases per decade were observed for non-HDL cholesterol [7% per mmol/L; 95% confidence interval (CI), 3–10%] and systolic BP (4% per 20 mmHg; 95% CI, 1–8%), while a minor HR increase per decade was observed for BMI (7% per 10 kg/m2; 95% CI, 1–13%). Conclusion The results demonstrate that all classic CVD risk factors are still relevant in Europe, irrespective of regional area. Preventive strategies should focus on risk factors with the greatest population attributable risk., AIMS: The regional and temporal differences in the associations between cardiovascular disease (CVD) and its classic risk factors are unknown. The current study examined these associations in different European regions over a 30-year period.METHODS AND RESULTS: The study sample comprised 553 818 individuals from 49 cohorts in 11 European countries (baseline: 1982-2012) who were followed up for a maximum of 10 years. Risk factors [sex, smoking, diabetes, non-HDL cholesterol, systolic blood pressure (BP), and body mass index (BMI)] and CVD events (coronary heart disease or stroke) were harmonized across cohorts. Risk factor-outcome associations were analysed using multivariable-adjusted Cox regression models, and differences in associations were assessed using meta-regression. The differences in the risk factor-CVD associations between central Europe, northern Europe, southern Europe, and the UK were generally small. Men had a slightly higher hazard ratio (HR) in southern Europe (P = 0.043 for overall difference), and those with diabetes had a slightly lower HR in central Europe (P = 0.022 for overall difference) compared with the other regions. Of the six CVD risk factors, minor HR decreases per decade were observed for non-HDL cholesterol [7% per mmol/L; 95% confidence interval (CI), 3-10%] and systolic BP (4% per 20 mmHg; 95% CI, 1-8%), while a minor HR increase per decade was observed for BMI (7% per 10 kg/m2; 95% CI, 1-13%).CONCLUSION: The results demonstrate that all classic CVD risk factors are still relevant in Europe, irrespective of regional area. Preventive strategies should focus on risk factors with the greatest population attributable risk.
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- 2024
29. Polar Vantage and Oura Physical Activity and Sleep Trackers: Validation and Comparison Study
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André Henriksen, Frode Svartdal, Sameline Grimsgaard, Gunnar Hartvigsen, and Laila Arnesdatter Hopstock
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Medicine - Abstract
BackgroundConsumer-based activity trackers are increasingly used in research, as they have the potential to promote increased physical activity and can be used for estimating physical activity among participants. However, the accuracy of newer consumer-based devices is mostly unknown, and validation studies are needed. ObjectiveThe objective of this study was to compare the Polar Vantage watch (Polar Electro Oy) and Oura ring (generation 2; Ōura Health Oy) activity trackers to research-based instruments for measuring physical activity, total energy expenditure, resting heart rate, and sleep duration in free-living adults. MethodsA total of 21 participants wore 2 consumer-based activity trackers (Polar watch and Oura ring), an ActiGraph accelerometer (ActiGraph LLC), and an Actiheart accelerometer and heart rate monitor (CamNtech Ltd) and completed a sleep diary for up to 7 days. We assessed Polar watch and Oura ring validity and comparability for measuring physical activity, total energy expenditure, resting heart rate (Oura), and sleep duration. We analyzed repeated measures correlations, Bland-Altman plots, and mean absolute percentage errors. ResultsThe Polar watch and Oura ring values strongly correlated (P
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- 2022
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30. A breathing space: how young Norwegian women engaging psychomotor physiotherapy to address long-term health disorders narrate their experiences.
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Grimsgaard, Elisabeth, Eik, Hedda, Bjorbækmoe, Wenche, and Ahlsen, Birgitte
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IntroductionObjectiveMethodFindingsConclusionIn Norway, as elsewhere, young people may experience psychological distress and long-lasting pain. Such health disorders can be complex, leading some young people to seek psychomotor physiotherapy treatment. Thus far, however, there has been little qualitative investigation of their experiences.The purpose of this study was to gain new knowledge about the illness experiences of young people with long-term health disorders engaging psychomotor physiotherapy.Qualitative interviews with ten Norwegian women aged 16–24 in psychomotor physiotherapy were analyzed within a narrative framework.The participants’ treatment experiences take place in the context of a long history of pain, distress, and lack of understanding and support. Their stories tell of being threatened by illness and other difficult life events, and of being placed under further stress by a prolonged and disruptive quest for help within the healthcare system. For participants, psychomotor physiotherapy represents a breathing space where their illness experiences are acknowledged, enabling them to find rest and explore their bodily reactions and habits.Long-term health disorders represent significant disruptions to the daily lives and relationships of young women. It is important to acknowledge the illness experiences of these young women and establish trustful therapeutic relationships. Psychomotor physiotherapy may offer significant potential as a means to help young people explore and make sense of their illness experiences. [ABSTRACT FROM AUTHOR]
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- 2024
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31. Simple cardiovascular risk stratification by replacing total serum cholesterol with anthropometric measures: The MORGAM prospective cohort project
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Victoria Rosberg, Julie KK Vishram-Nielsen, Anna M. Dyrvig Kristensen, Manan Pareek, Thomas S.G. Sehested, Peter M Nilsson, Allan Linneberg, Luigi Palmieri, Simona Giampaoli, Chiara Donfrancesco, Frank Kee, Giuseppe Mancia, Giancarlo Cesana, Giovanni Veronesi, Guido Grassi, Kari Kuulasmaa, Veikko Salomaa, Tarja Palosaari, Susana Sans, Jean Ferrieres, Jean Dallongeville, Stefan Söderberg, Marie Moitry, Wojciech Drygas, Abdonas Tamosiunas, Annette Peters, Hermann Brenner, Ben Schöttker, Sameline Grimsgaard, Tor Biering-Sørensen, and Michael H Olsen
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Adipose tissue ,Assessment, risk ,Body mass index ,Cardiovascular diseases ,Cholesterol ,Waist-hip ratio ,Medicine - Abstract
To assess whether anthropometric measures (body mass index [BMI], waist-hip ratio [WHR], and estimated fat mass [EFM]) are independently associated with major adverse cardiovascular events (MACE), and to assess their added prognostic value compared with serum total-cholesterol. The study population comprised 109,509 individuals (53% men) from the MORGAM-Project, aged 19–97 years, without established cardiovascular disease, and not on antihypertensive treatment. While BMI was reported in all, WHR and EFM were reported in ∼52,000 participants. Prognostic importance of anthropometric measurements and total-cholesterol was evaluated using adjusted Cox proportional-hazards regression, logistic regression, area under the receiver-operating-characteristic curve (AUCROC), and net reclassification improvement (NRI). The primary endpoint was MACE, a composite of stroke, myocardial infarction, or death from coronary heart disease. Age interacted significantly with anthropometric measures and total-cholesterol on MACE (P ≤ 0.003), and therefore age-stratified analyses (
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- 2022
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32. Dataset of consumer-based activity trackers as a tool for physical activity monitoring in epidemiological studies during the COVID-19 Pandemic
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André Henriksen, Erlend Johannessen, Gunnar Hartvigsen, Sameline Grimsgaard, and Laila Arnesdatter Hopstock
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Energy expenditure ,Steps ,Smart watch ,Fitness tracker ,Public health ,Lockdown ,Computer applications to medicine. Medical informatics ,R858-859.7 ,Science (General) ,Q1-390 - Abstract
Physical activity (PA) data were downloaded from 113 participants who owned a Garmin or Fitbit activity tracker in 2019 and 2020. Upon participant authorization, data were automatically downloaded from the Garmin and Fitbit cloud storages. The mSpider tool, a solution for automatic and continuous data extraction from activity tracker providers, were used to download participant data. Available data are daily averages by year, as well as monthly averages between 2019 and 2020, for steps, activity energy expenditure (AEE), total energy expenditure (TEE), moderate-to-vigorous physical activity (MVPA), light PA (LPA), moderate PA (MPA), vigorous PA (VPA), and sedentary time. In addition, March 2020 was divided in two, giving the daily average before and after the Norwegian COVID-19 lockdown date. Raw daily values for these variables are also included in a separate file. In addition, daily values for non-wear time are also include as raw data.In a previous study, differences between months, i.e., comparing 2019 with 2020 for months between March to December, were analysed for steps, MVPA, and AEE [1]. Further insights may be achieved by exploring other variables. This includes: (1) monthly averages for TEE, LPA, MPA, VPA, and sedentary time, (2) yearly averages (2019 and 2020) for steps, MVPA, TEE, AEE, LPA, MPA, VPA, and sedentary time (3) monthly average for steps, MVPA, TEE, AEE, LPA, MPA, VPA, and sedentary time for January, February, and March 2019, as well as March 2020. Additional analysis can also be conducted on the raw data.
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- 2022
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33. Brukermedvirkning i forskning – for lite, for sent
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Bjåstad, Jon Fauskanger, primary, Aas, Sigve Nyvik, primary, Distefano, Marita Borg, primary, Berglen, Gunnhild, primary, Haugen, Nikolai Raaby, primary, Gjesten, Martha Therese, primary, Erga, Aleksander Hagen, primary, Pettersen, Ingvild, primary, Nordvoll, Laila Yvonne, primary, Sundström, Mariann, primary, and Grimsgaard, Sameline, primary
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- 2024
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34. National health registries – a ‘goldmine’ for studying non-communicable disease occurrence in Norway – the NCDNOR project
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NYSTAD, WENCHE, primary, HJELLVIK, VIDAR, additional, LARSEN, INGER K., additional, ROBSAHM, TRUDE E., additional, SUND, ERIK R., additional, KROKSTAD, STEINAR, additional, HOPSTOCK, LAILA A., additional, GRIMSGAARD, SAMELINE, additional, LANGHAMMER, ARNULF, additional, BRAMNESS, JØRGEN G., additional, WISLØFF, TORBJØRN, additional, LERGENMULLER, SIMON, additional, DALENE, KNUT E., additional, MEYER, HAAKON E., additional, HOLVIK, KRISTIN, additional, HELGELAND, JON, additional, KARLSTAD, ØYSTEIN, additional, and ARIANSEN, INGER, additional
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- 2023
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35. Lifestyle factors as mediators of area-level socioeconomic differentials in mental health and cognitive function: the Tromsø Study
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Tiwari, Sweta, primary, Cerin, Ester, additional, Wilsgaard, Tom, additional, Løvsletten, Ola, additional, Grimsgaard, Sameline, additional, Hopstock, Laila Arnesdatter, additional, Schirmer, Henrik, additional, Rosengren, Annika, additional, Kristoffersen, Kathrine, additional, and Løchen, Maja-Lisa, additional
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- 2023
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36. Regional and temporal differences in the associations between cardiovascular disease and its classic risk factors: an analysis of 49 cohorts from 11 European countries
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Reinikainen, Jaakko, primary, Kuulasmaa, Kari, additional, Oskarsson, Viktor, additional, Amouyel, Philippe, additional, Biasch, Katia, additional, Brenner, Hermann, additional, De Ponti, Roberto, additional, Donfrancesco, Chiara, additional, Drygas, Wojciech, additional, Ferrieres, Jean, additional, Grassi, Guido, additional, Grimsgaard, Sameline, additional, Iacoviello, Licia, additional, Jousilahti, Pekka, additional, Kårhus, Line L, additional, Kee, Frank, additional, Linneberg, Allan, additional, Luksiene, Dalia, additional, Mariño, Joany, additional, Moitry, Marie, additional, Palmieri, Luigi, additional, Peters, Annette, additional, Piwonska, Aleksandra, additional, Quarti-Trevano, Fosca, additional, Salomaa, Veikko, additional, Sans, Susana, additional, Schmidt, Carsten Oliver, additional, Schöttker, Ben, additional, Söderberg, Stefan, additional, Tamosiunas, Abdonas, additional, Thorand, Barbara, additional, Tunstall-Pedoe, Hugh, additional, Vanuzzo, Diego, additional, Veronesi, Giovanni, additional, Woodward, Mark, additional, Lekadir, Karim, additional, and Niiranen, Teemu, additional
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- 2023
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37. Complex lifestyle intervention among inactive older adults with elevated cardiovascular disease risk and obesity: a mixed-method, single-arm feasibility study for RESTART—a randomized controlled trial
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Deraas, Trygve S., Hopstock, Laila, Henriksen, Andre, Morseth, Bente, Sand, Anne Sofie, Njølstad, Inger, Pedersen, Sigurd, Sagelv, Edvard, Johansson, Jonas, and Grimsgaard, Sameline
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- 2021
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38. Drinking alcohol in moderation is associated with lower rate of all-cause mortality in individuals with higher rather than lower educational level: findings from the MORGAM project
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Di Castelnuovo, A, Bonaccio, M, Costanzo, S, Mcelduff, P, Linneberg, A, Salomaa, V, Männistö, S, Ferrières, J, Dallongeville, J, Thorand, B, Brenner, H, Ferrario, M, Veronesi, G, Tamosiunas, A, Grimsgaard, S, Drygas, W, Malyutina, S, Söderberg, S, Nordendahl, M, Kee, F, Grassi, G, Dabboura, S, Borchini, R, Westermann, D, Schrage, B, Zeller, T, Kuulasmaa, K, Blankenberg, S, Donati, M, Iacoviello, L, de Gaetano, G, Di Castelnuovo, Augusto, Bonaccio, Marialaura, Costanzo, Simona, McElduff, Patrick, Linneberg, Allen, Salomaa, Veikko, Männistö, Satu, Ferrières, Jean, Dallongeville, Jean, Thorand, Barbara, Brenner, Hermann, Ferrario, Marco, Veronesi, Giovanni, Tamosiunas, Abdonas, Grimsgaard, Sameline, Drygas, Wojciech, Malyutina, Sofia, Söderberg, Stefan, Nordendahl, Maria, Kee, Frank, Grassi, Guido, Dabboura, Salim, Borchini, Rossana, Westermann, Dirk, Schrage, Benedikt, Zeller, Tanja, Kuulasmaa, Kari, Blankenberg, Stefan, Donati, Maria Benedetta, Iacoviello, Licia, de Gaetano, Giovanni, Di Castelnuovo, A, Bonaccio, M, Costanzo, S, Mcelduff, P, Linneberg, A, Salomaa, V, Männistö, S, Ferrières, J, Dallongeville, J, Thorand, B, Brenner, H, Ferrario, M, Veronesi, G, Tamosiunas, A, Grimsgaard, S, Drygas, W, Malyutina, S, Söderberg, S, Nordendahl, M, Kee, F, Grassi, G, Dabboura, S, Borchini, R, Westermann, D, Schrage, B, Zeller, T, Kuulasmaa, K, Blankenberg, S, Donati, M, Iacoviello, L, de Gaetano, G, Di Castelnuovo, Augusto, Bonaccio, Marialaura, Costanzo, Simona, McElduff, Patrick, Linneberg, Allen, Salomaa, Veikko, Männistö, Satu, Ferrières, Jean, Dallongeville, Jean, Thorand, Barbara, Brenner, Hermann, Ferrario, Marco, Veronesi, Giovanni, Tamosiunas, Abdonas, Grimsgaard, Sameline, Drygas, Wojciech, Malyutina, Sofia, Söderberg, Stefan, Nordendahl, Maria, Kee, Frank, Grassi, Guido, Dabboura, Salim, Borchini, Rossana, Westermann, Dirk, Schrage, Benedikt, Zeller, Tanja, Kuulasmaa, Kari, Blankenberg, Stefan, Donati, Maria Benedetta, Iacoviello, Licia, and de Gaetano, Giovanni
- Abstract
The association between socioeconomic status (SES) and alcohol-related diseases has been widely explored. Less is known, however, on whether the association of moderate drinking with all-cause mortality is modified by educational level (EL). Using harmonized data from 16 cohorts in the MORGAM Project (N = 142,066) the association of pattern of alcohol intake with hazard of all-cause mortality across EL (lower = primary-school; middle = secondary-school; higher = university/college degree) was assessed using multivariable Cox-regression and spline curves. A total of 16,695 deaths occurred in 11.8 years (median). In comparison with life-long abstainers, participants drinking 0.1–10 g/d of ethanol had 13% (HR = 0.87; 95%CI: 0.74–1.02), 11% (HR = 0.89; 0.84–0.95) and 5% (HR = 0.95; 0.89–1.02) lower rate of death in higher, middle and lower EL, respectively. Conversely, drinkers > 20 g/d had 1% (HR = 1.01; 0.82–1.25), 10% (HR = 1.10; 1.02–1.19) and 17% (HR = 1.17; 1.09–1.26) higher rate of death. The association of alcohol consumption with all-cause mortality was nonlinear, with a different J-shape by EL levels. It was consistent across both sexes and in various approaches of measuring alcohol consumption, including combining quantity and frequency and it was more evident when the beverage of preference was wine. We observed that drinking in moderation (≤ 10 g/d) is associated with lower mortality rate more evidently in individuals with higher EL than in people with lower EL, while heavy drinking is associated with higher mortality rate more evidently in individuals with lower EL than in people with higher EL, suggesting that advice on reducing alcohol intake should especially target individuals of low EL.
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- 2023
39. SMIM1 absence is associated with reduced energy expenditure and excess weight
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Banasik, Karina, Bay, Jakob, Boldsen, Jens Kjærgaard, Brodersen, Thorsten, Brunak, Søren, Burgdorf, Kristoffer, Chalmer, Mona Ameri, Didriksen, Maria, Dinh, Khoa Manh, Dowsett, Joseph, Erikstrup, Christian, Feenstra, Bjarke, Geller, Frank, Gudbjartsson, Daniel, Hansen, Thomas Folkmann, Hindhede, Lotte, Hjalgrim, Henrik, Jacobsen, Rikke Louise, Jemec, Gregor, Jensen, Bitten Aagaard, Kaspersen, Katrine, Kjerulff, Bertram Dalskov, Kogelman, Lisette, Hørup Larsen, Margit Anita, Louloudis, Ioannis, Lundgaard, Agnete, Susan, Mikkelsen, Christina, Nissen, Ioanna, Nyegaard, Mette, Ostrowski, Sisse Rye, Pedersen, Ole Birger, Henriksen, Alexander Pil, Rohde, Palle Duun, Rostgaard, Klaus, Schwinn, Michael, Stefansson, Kari, Stefánsson, Hreinn, Sørensen, Erik, þorsteinsdóttir, Unnur, Thørner, Lise Wegner, Bruun, Mie Topholm, Ullum, Henrik, Werge, Thomas, Westergaard, David, Chen, Ji, Spracklen, Cassandra N., Marenne, Gaëlle, Varshney, Arushi, Corbin, Laura J., Luan, Jian’an, Willems, Sara M., Wu, Ying, Zhang, Xiaoshuai, Horikoshi, Momoko, Boutin, Thibaud S., Mägi, Reedik, Waage, Johannes, Li-Gao, Ruifang, Katie Chan, Kei Hang, Yao, Jie, Anasanti, Mila D., Chu, Audrey Y., Claringbould, Annique, Heikkinen, Jani, Hong, Jaeyoung, Hottenga, Jouke-Jan, Huo, Shaofeng, Kaakinen, Marika A., Louie, Tin, März, Winfried, Moreno-Macias, Hortensia, Ndungu, Anne, Nelson, Sarah C., Nolte, Ilja M., North, Kari E., Raulerson, Chelsea K., Ray, Debashree, Rohde, Rebecca, Rybin, Denis, Schurmann, Claudia, Sim, Xueling, Southam, Loz, Stewart, Isobel D., Wang, Carol A., Wang, Yujie, Wu, Peitao, Zhang, Weihua, Ahluwalia, Tarunveer S., Appel, Emil V.R., Bielak, Lawrence F., Brody, Jennifer A., Burtt, Noël P., Cabrera, Claudia P., Cade, Brian E., Chai, Jin Fang, Chai, Xiaoran, Chang, Li-Ching, Chen, Chien-Hsiun, Chen, Brian H., Chitrala, Kumaraswamy Naidu, Chiu, Yen-Feng, de Haan, Hugoline G., Delgado, Graciela E., Demirkan, Ayse, Duan, Qing, Engmann, Jorgen, Fatumo, Segun A., Gayán, Javier, Giulianini, Franco, Gong, Jung Ho, Gustafsson, Stefan, Hai, Yang, Hartwig, Fernando P., He, Jing, Heianza, Yoriko, Huang, Tao, Huerta-Chagoya, Alicia, Hwang, Mi Yeong, Jensen, Richard A., Kawaguchi, Takahisa, Kentistou, Katherine A., Kim, Young Jin, Kleber, Marcus E., Kooner, Ishminder K., Lai, Shuiqing, Lange, Leslie A., Langefeld, Carl D., Lauzon, Marie, Li, Man, Ligthart, Symen, Liu, Jun, Loh, Marie, Long, Jirong, Lyssenko, Valeriya, Mangino, Massimo, Marzi, Carola, Montasser, May E., Nag, Abhishek, Nakatochi, Masahiro, Noce, Damia, Noordam, Raymond, Pistis, Giorgio, Preuss, Michael, Raffield, Laura, Rasmussen-Torvik, Laura J., Rich, Stephen S., Robertson, Neil R., Rueedi, Rico, Ryan, Kathleen, Sanna, Serena, Saxena, Richa, Schraut, Katharina E., Sennblad, Bengt, Setoh, Kazuya, Smith, Albert V., Southam, Lorraine, Sparsø, Thomas, Strawbridge, Rona J., Takeuchi, Fumihiko, Tan, Jingyi, Trompet, Stella, van den Akker, Erik, van der Most, Peter J., Verweij, Niek, Vogel, Mandy, Wang, Heming, Wang, Chaolong, Wang, Nan, Warren, Helen R., Wen, Wanqing, Wilsgaard, Tom, Wong, Andrew, Wood, Andrew R., Xie, Tian, Zafarmand, Mohammad Hadi, Zhao, Jing-Hua, Zhao, Wei, Amin, Najaf, Arzumanyan, Zorayr, Astrup, Arne, Bakker, Stephan J.L., Baldassarre, Damiano, Beekman, Marian, Bergman, Richard N., Bertoni, Alain, Blüher, Matthias, Bonnycastle, Lori L., Bornstein, Stefan R., Bowden, Donald W., Cai, Qiuyin, Campbell, Archie, Campbell, Harry, Chang, Yi Cheng, de Geus, Eco J.C., Dehghan, Abbas, Du, Shufa, Eiriksdottir, Gudny, Farmaki, Aliki Eleni, Frånberg, Mattias, Fuchsberger, Christian, Gao, Yutang, Gjesing, Anette P., Goel, Anuj, Han, Sohee, Hartman, Catharina A., Herder, Christian, Hicks, Andrew A., Hsieh, Chang-Hsun, Hsueh, Willa A., Ichihara, Sahoko, Igase, Michiya, Ikram, M. Arfan, Johnson, W. Craig, Jørgensen, Marit E., Joshi, Peter K., Kalyani, Rita R., Kandeel, Fouad R., Katsuya, Tomohiro, Khor, Chiea Chuen, Kiess, Wieland, Kolcic, Ivana, Kuulasmaa, Teemu, Kuusisto, Johanna, Läll, Kristi, Lam, Kelvin, Lawlor, Deborah A., Lee, Nanette R., Lemaitre, Rozenn N., Li, Honglan, Lin, Shih-Yi, Lindström, Jaana, Linneberg, Allan, Liu, Jianjun, Lorenzo, Carlos, Matsubara, Tatsuaki, Matsuda, Fumihiko, Mingrone, Geltrude, Mooijaart, Simon, Moon, Sanghoon, Nabika, Toru, Nadkarni, Girish N., Nadler, Jerry L., Nelis, Mari, Neville, Matt J., Norris, Jill M., Ohyagi, Yasumasa, Peters, Annette, Peyser, Patricia A., Polasek, Ozren, Qi, Qibin, Raven, Dennis, Reilly, Dermot F., Reiner, Alex, Rivideneira, Fernando, Roll, Kathryn, Rudan, Igor, Sabanayagam, Charumathi, Sandow, Kevin, Sattar, Naveed, Schürmann, Annette, Shi, Jinxiu, Stringham, Heather M., Taylor, Kent D., Teslovich, Tanya M., Thuesen, Betina, Timmers, Paul R.H.J., Tremoli, Elena, Tsai, Michael Y., Uitterlinden, Andre, van Dam, Rob M., van Heemst, Diana, van Hylckama Vlieg, Astrid, Van Vliet-Ostaptchouk, Jana V., Vangipurapu, Jagadish, Vestergaard, Henrik, Wang, Tao, Willems van Dijk, Ko, Zemunik, Tatijana, Abecasis, Goncalo R., Adair, Linda S., Aguilar-Salinas, Carlos Alberto, Alarcón-Riquelme, Marta E., An, Ping, Aviles-Santa, Larissa, Becker, Diane M., Beilin, Lawrence J., Bergmann, Sven, Bisgaard, Hans, Black, Corri, Boehnke, Michael, Boerwinkle, Eric, Böhm, Bernhard O., Bønnelykke, Klaus, Boomsma, D.I., Bottinger, Erwin P., Buchanan, Thomas A., Canouil, Mickaël, Caulfield, Mark J., Chambers, John C., Chasman, Daniel I., Ida Chen, Yii-Der, Cheng, Ching-Yu, Collins, Francis S., Correa, Adolfo, Cucca, Francesco, Janaka de Silva, H., Dedoussis, George, Elmståhl, Sölve, Evans, Michele K., Ferrannini, Ele, Ferrucci, Luigi, Florez, Jose C., Franks, Paul W., Frayling, Timothy M., Froguel, Philippe, Gigante, Bruna, Goodarzi, Mark O., Gordon-Larsen, Penny, Grallert, Harald, Grarup, Niels, Grimsgaard, Sameline, Groop, Leif, Gudnason, Vilmundur, Guo, Xiuqing, Hamsten, Anders, Hansen, Torben, Hayward, Caroline, Heckbert, Susan R., Horta, Bernardo L., Huang, Wei, Ingelsson, Erik, James, Pankow S., Jarvelin, Marjo-Ritta, Jonas, Jost B., Jukema, J. Wouter, Kaleebu, Pontiano, Kaplan, Robert, Kardia, Sharon L.R., Kato, Norihiro, Keinanen-Kiukaanniemi, Sirkka M., Kim, Bong-Jo, Kivimaki, Mika, Koistinen, Heikki A., Kooner, Jaspal S., Körner, Antje, Kovacs, Peter, Kuh, Diana, Kumari, Meena, Kutalik, Zoltan, Laakso, Markku, Lakka, Timo A., Launer, Lenore J., Leander, Karin, Li, Huaixing, Lin, Xu, Lind, Lars, Lindgren, Cecilia, Liu, Simin, Loos, Ruth J.F., Magnusson, Patrik K.E., Mahajan, Anubha, Metspalu, Andres, Mook-Kanamori, Dennis O., Mori, Trevor A., Munroe, Patricia B., Njølstad, Inger, O'Connell, Jeffrey R., Oldehinkel, Albertine J., Ong, Ken K., Padmanabhan, Sandosh, Palmer, Colin N.A., Palmer, Nicholette D., Pedersen, Oluf, Pennell, Craig E., Porteous, David J., Pramstaller, Peter P., Province, Michael A., Psaty, Bruce M., Qi, Lu, Raffel, Leslie J., Rauramaa, Rainer, Redline, Susan, Ridker, Paul M., Rosendaal, Frits R., Saaristo, Timo E., Sandhu, Manjinder, Saramies, Jouko, Schneiderman, Neil, Schwarz, Peter, Scott, Laura J., Selvin, Elizabeth, Sever, Peter, Shu, Xiao-Ou, Slagboom, P. Eline, Small, Kerrin S., Smith, Blair H., Snieder, Harold, Sofer, Tamar, Sørensen, Thorkild I.A., Spector, Tim D., Stanton, Alice, Steves, Claire J., Stumvoll, Michael, Sun, Liang, Tabara, Yasuharu, Tai, E. Shyong, Timpson, Nicholas J., Tönjes, Anke, Tuomilehto, Jaakko, Tusie, Teresa, Uusitupa, Matti, van der Harst, Pim, van Duijn, Cornelia, Vitart, Veronique, Vollenweider, Peter, Vrijkotte, Tanja G.M., Wagenknecht, Lynne E., Walker, Mark, Wang, Ya X., Wareham, Nick J., Watanabe, Richard M., Watkins, Hugh, Wei, Wen B., Wickremasinghe, Ananda R., Willemsen, Gonneke, Wilson, James F., Wong, Tien-Yin, Wu, Jer-Yuarn, Xiang, Anny H., Yanek, Lisa R., Yengo, Loïc, Yokota, Mitsuhiro, Zeggini, Eleftheria, Zheng, Wei, Zonderman, Alan B., Rotter, Jerome I., Gloyn, Anna L., McCarthy, Mark I., Dupuis, Josée, Meigs, James B., Scott, Robert A., Prokopenko, Inga, Leong, Aaron, Liu, Ching-Ti, Parker, Stephen C.J., Mohlke, Karen L., Langenberg, Claudia, Wheeler, Eleanor, Morris, Andrew P., Barroso, Inês, Stefanucci, Luca, Moslemi, Camous, Tomé, Ana R., Virtue, Samuel, Bidault, Guillaume, Gleadall, Nicholas S., Watson, Laura P.E., Kwa, Jing E., Burden, Frances, Farrow, Samantha, Võsa, Urmo, Burling, Keith, Walker, Lindsay, Ord, John, Barker, Peter, Warner, James, Frary, Amy, Renhstrom, Karola, Ashford, Sofie E., Piper, Jo, Biggs, Gail, Erber, Wendy N., Hoffman, Gary J., Schoenmakers, Nadia, Rieneck, Klaus, Dziegiel, Morten H., Azzu, Vian, Vacca, Michele, Aparicio, Hugo Javier, Hui, Qin, Cho, Kelly, Sun, Yan V., Wilson, Peter W., Bayraktar, Omer A., Vidal-Puig, Antonio, Ostrowski, Sisse R., Astle, William J., Olsson, Martin L., Storry, Jill R., Pedersen, Ole B., Ouwehand, Willem H., Chatterjee, Krishna, Vuckovic, Dragana, and Frontini, Mattia
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- 2024
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40. Regional and temporal differences in the associations between cardiovascular disease and its classic risk factors: an analysis of 49 cohorts from 11 European countries.
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Reinikainen, Jaakko, Kuulasmaa, Kari, Oskarsson, Viktor, Amouyel, Philippe, Biasch, Katia, Brenner, Hermann, Ponti, Roberto De, Donfrancesco, Chiara, Drygas, Wojciech, Ferrieres, Jean, Grassi, Guido, Grimsgaard, Sameline, Iacoviello, Licia, Jousilahti, Pekka, Kårhus, Line L, Kee, Frank, Linneberg, Allan, Luksiene, Dalia, Mariño, Joany, and Moitry, Marie
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- 2024
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41. Lifestyle factors as mediators of area-level socioeconomic differentials in mental health and cognitive function: the Tromsø Study.
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Tiwari, Sweta, Cerin, Ester, Wilsgaard, Tom, Løvsletten, Ola, Grimsgaard, Sameline, Hopstock, Laila Arnesdatter, Schirmer, Henrik, Rosengren, Annika, Kristoffersen, Kathrine, and Løchen, Maja-Lisa
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LIFESTYLES ,CROSS-sectional method ,MENTAL health ,COGNITION ,SOCIOECONOMIC status ,PHYSICAL activity ,SOCIAL classes ,FACTOR analysis ,DESCRIPTIVE statistics ,RESEARCH funding ,SMOKING - Published
- 2024
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42. The Untapped Power of Health and Wellness Coaching
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Howard, Kelly, primary, Gantt, Cynthia J, additional, Grimsgaard Noyes, Sara, additional, and Franzos, M Alaric, additional
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- 2023
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43. Lipid Levels During Adult Lifetime in Men and Women With and Without a Subsequent Incident Myocardial Infarction: A Longitudinal Analysis of Data From the Tromsø Study 1974 to 2016
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Albrektsen, Grethe, primary, Wilsgaard, Tom, additional, Heuch, Ivar, additional, Løchen, Maja‐Lisa, additional, Thelle, Dag Steinar, additional, Njølstad, Inger, additional, Grimsgaard, Sameline, additional, and Bønaa, Kaare Harald, additional
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- 2023
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44. Associations between postprandial triglyceride concentrations and sex, age, and body mass index: cross-sectional analyses from the Tromsø study 2015–2016
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Mikkelsen, Mari, primary, Wilsgaard, Tom, additional, Grimsgaard, Sameline, additional, Hopstock, Laila A., additional, and Hansson, Patrik, additional
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- 2023
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45. Trends in prevalence, treatment and control of hypertension in 38,825 adults over 36 years in Tromsø prospective study
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Desai, Trishna, primary, Clarke, Robert, additional, Ross, Stephanie, additional, Grimsgaard, Sameline, additional, Njølstad, Inger, additional, and Lewington, Sarah, additional
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- 2023
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46. What counts? A Delphi consensus-based approach to interpreting accreditation standards for Direct Client Activities in clinical psychology and clinical neuropsychology programs.
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Anderson, Rebecca A., Gooi, Chien Hoong, Oxenham, Vincent, Player, Michelle, Grimsgaard, Cathrine, Collison, James, Kambouropoulos, Alexa, and Moses, Karen
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CONSENSUS (Social sciences) ,COGNITION disorders ,NEUROPSYCHOLOGY ,ACCREDITATION ,HOSPITAL medical staff ,CLINICAL psychology ,BENCHMARKING (Management) ,CLINICAL competence ,ANXIETY ,SUPERVISION of employees ,DELPHI method - Abstract
Despite operating from the same professional accreditation standards, discrepancies in what is recorded as Direct Client Activities (DCA) in postgraduate psychology trainee logbooks have been noted across training programs in Australia. The aim of this study was to create a consensus-based list of DCA to guide the completion of trainee logbooks while undertaking practicums in clinical psychology or clinical neuropsychology. A modified Delphi approach was used to gather data across three rounds. Two expert panels, representing the two areas of practice endorsement (AoPEs), rated the degree to which they agreed or disagreed with a range of activities being recorded as DCA in trainee logbooks. Activities with over 80% agreement or disagreement during any round were accepted or rejected from the final list, respectively. Sixteen activities for clinical psychology and 30 activities for clinical neuropsychology were endorsed by the expert panels. Only nine activities across the two panels did not reach consensus over the three rounds. This study has created a list of consensus activities within these two AoPEs which will facilitate benchmarking activities, and reduce confusion and anxiety for trainees, supervisors, and placement coordinators. Discrepancies do, however, remain across the AoPEs, warranting further clarification and definition refinement. What is already known about this topic: Logbooks are a key strategy in ensuring individual trainees and postgraduate training programs are meeting minimum standards set by accrediting bodies. Although required by the Australian Psychology Accreditation Council (APAC) to be recorded in trainee logbooks, there is a lack of consensus across Australian postgraduate psychology program providers as to what constitutes "Direct Client Activities". Inconsistent logging practices prevents benchmarking and creates confusion and anxiety for trainees, supervisors, and placement coordinators. What this topic adds: This paper was the first, to our knowledge, to obtain expert consensus on trainee Direct Client Activities for logbook recording within the clinical psychology and clinical neuropsychology areas of practice endorsement. The list provides greater certainty for "what counts" as Direct Client Activities for logbook recording within these two areas of practice endorsement, with 16 clinical psychology and 30 clinical neuropsychology activities endorsed. There is a need to better clarify the rationale and principles for recording Direct Client Activities across areas of practice endorsement, to inform ongoing practices in these areas. [ABSTRACT FROM AUTHOR]
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- 2023
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47. Association between neighborhood health behaviors and body mass index in Northern Norway: evidence from the Tromsø Study.
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Sari, Emre, Moilanen, Mikko, Bambra, Clare, Grimsgaard, Sameline, and Njølstad, Inger
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OBESITY ,LEISURE ,CONFIDENCE intervals ,LIFE course approach ,PHYSICAL activity ,HEALTH behavior ,DESCRIPTIVE statistics ,DISEASE prevalence ,RESEARCH funding ,BODY mass index ,RESIDENTIAL patterns ,NEIGHBORHOOD characteristics ,SECONDARY analysis - Abstract
Aim: The prevalence of overweight and obesity has risen rapidly worldwide, and the ongoing obesity pandemic is one of the most severe public health concerns in modern society. The average body mass index (BMI) of people living in Northern Norway has also steadily increased since the late 1970s. This study aimed to understand how individuals' health behavior is associated with the general health behavior of the people in their neighborhood. Methods: Using the population-based Tromsø Study, we examined the life course association between average leisure time physical activity at the neighborhood level and the BMI of individuals living in the same neighborhood. We used a longitudinal dataset following 25,604 individuals living in 33 neighborhoods and performed a linear mixed-effects analysis. Results: The results showed that participants living in neighborhoods whose residents were more physically active during their leisure time, were likely to have a significantly lower BMI (−0.9 kg/m², 95% CI −1.5 to −0.4). Also, individuals living in neighborhoods whose residents were doing mainly manual work, had significantly higher BMIs (0.7 kg/m², 95% CI 0.4−1.0). Conclusions: Our results showed a strong association between the average leisure time physical activity level of neighborhood residents and the higher BMI levels of residents of the same neighborhood. [ABSTRACT FROM AUTHOR]
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- 2023
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48. Data from national health registers as endpoints for the Tromsø Study: Correctness and completeness of stroke diagnoses.
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Varmdal, Torunn, Løchen, Maja-Lisa, Wilsgaard, Tom, Njølstad, Inger, Nyrnes, Audhild, Grimsgaard, Sameline, and Mathiesen, Ellisiv B.
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STROKE diagnosis ,REPORTING of diseases ,DATA quality ,PREDICTIVE tests ,CONFIDENCE intervals ,CARDIOVASCULAR diseases ,DESCRIPTIVE statistics ,SENSITIVITY & specificity (Statistics) ,DIAGNOSTIC errors ,EPIDEMIOLOGICAL research - Abstract
Aim: To assess whether stroke diagnoses in national health registers are sufficiently correct and complete to replace manual collection of endpoint data for the Tromsø Study, a population-based epidemiological study. Method: Using the Tromsø Study Cardiovascular Disease Register for 2013–2014 as the gold standard, we calculated correctness (defined as positive predictive value, PPV) and completeness (defined as sensitivity) of stroke cases in four different data subsets derived from the Norwegian Patient Register and the Norwegian Stroke Register. We calculated the sensitivity and PPV with 95% confidence intervals (CIs) assuming a normal approximation of the binomial distribution. Results: In the Norwegian Stroke Register we found a sensitivity of 79.8% (95% CI 74.2–85.4) and a PPV of 97.5% (95% CI 95.1–99.9). In the Norwegian Patient Register the sensitivity was 86.4% (95% CI 81.6–91.1) and the PPV was 84.2% (95% CI 79.2–89.2). The overall highest levels were found in a subset based on a linkage between the Norwegian Stroke Register and the Norwegian Patient Register, with a sensitivity of 88.9% (95% CI 84.5–93.3), and a PPV of 89.3% (95% CI 85.0–93.6). Conclusions: Data from the Norwegian Patient Register and from the linked data set between the Norwegian Patient Register and the Norwegian Stroke Register had acceptable levels of correctness and completeness to be considered as endpoint sources for the Tromsø Study Cardiovascular Disease Register. The benefits of using data from national registers as endpoints in epidemiological studies must be weighed against the impact of potentially decreased data quality. [ABSTRACT FROM AUTHOR]
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- 2023
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49. Child Welfare and the Significance of Family
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Nordby, Halvor, Netland, Grethe, Halsa, Astrid, Bennin, Camilla, Buer, Bjørn Arne, Fauske, Halvor, Grimsgaard, Cathrine, Grønseth, Anne Sigfrid, Gundersen, Eirik Christopher, Midtskogen, Bjørg, Rysst, Mari, Söderström, Kerstin, Nordby, Halvor, Netland, Grethe, and Halsa, Astrid
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child welfare, children’s rights, family, social work, barnevern, barns rettigheter, familie, sosialt arbeid ,thema EDItEUR::J Society and Social Sciences::JK Social services and welfare, criminology::JKS Social welfare and social services ,thema EDItEUR::J Society and Social Sciences::JK Social services and welfare, criminology::JKS Social welfare and social services::JKSB Welfare and benefit systems::JKSB1 Child welfare and youth services - Abstract
This book focuses on the significance of family in child welfare (CW) services from multidisciplinary perspectives. The authors are concerned with how families experience encounters with CW workers, how professional CW work with families is guided by rules and principles, and how social structures and ideologies influence CW work. Taken together, the chapters contribute to a comprehensive understanding of how CW workers should understand the importance of family for children. The book is important for everyone who works with the welfare of children and their families, and for those who educate CW workers. Although the context for many of the discussions in the book is Norwegian CW work, the topics are general, recognisable and relevant to similar discussions in other countries. The book is intended for CW workers, policymakers, researchers, and teachers and students in social work and child welfare study programmes.
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- 2023
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50. Simple cardiovascular risk stratification by replacing total serum cholesterol with anthropometric measures: The MORGAM prospective cohort project
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Rosberg, V, Vishram-Nielsen, J, Kristensen, A, Pareek, M, Sehested, T, Nilsson, P, Linneberg, A, Palmieri, L, Giampaoli, S, Donfrancesco, C, Kee, F, Mancia, G, Cesana, G, Veronesi, G, Grassi, G, Kuulasmaa, K, Salomaa, V, Palosaari, T, Sans, S, Ferrieres, J, Dallongeville, J, Soderberg, S, Moitry, M, Drygas, W, Tamosiunas, A, Peters, A, Brenner, H, Schottker, B, Grimsgaard, S, Biering-Sorensen, T, Olsen, M, Rosberg V., Vishram-Nielsen J. K., Kristensen A. M. D., Pareek M., Sehested T. S. G., Nilsson P. M., Linneberg A., Palmieri L., Giampaoli S., Donfrancesco C., Kee F., Mancia G., Cesana G., Veronesi G., Grassi G., Kuulasmaa K., Salomaa V., Palosaari T., Sans S., Ferrieres J., Dallongeville J., Soderberg S., Moitry M., Drygas W., Tamosiunas A., Peters A., Brenner H., Schottker B., Grimsgaard S., Biering-Sorensen T., Olsen M. H., Rosberg, V, Vishram-Nielsen, J, Kristensen, A, Pareek, M, Sehested, T, Nilsson, P, Linneberg, A, Palmieri, L, Giampaoli, S, Donfrancesco, C, Kee, F, Mancia, G, Cesana, G, Veronesi, G, Grassi, G, Kuulasmaa, K, Salomaa, V, Palosaari, T, Sans, S, Ferrieres, J, Dallongeville, J, Soderberg, S, Moitry, M, Drygas, W, Tamosiunas, A, Peters, A, Brenner, H, Schottker, B, Grimsgaard, S, Biering-Sorensen, T, Olsen, M, Rosberg V., Vishram-Nielsen J. K., Kristensen A. M. D., Pareek M., Sehested T. S. G., Nilsson P. M., Linneberg A., Palmieri L., Giampaoli S., Donfrancesco C., Kee F., Mancia G., Cesana G., Veronesi G., Grassi G., Kuulasmaa K., Salomaa V., Palosaari T., Sans S., Ferrieres J., Dallongeville J., Soderberg S., Moitry M., Drygas W., Tamosiunas A., Peters A., Brenner H., Schottker B., Grimsgaard S., Biering-Sorensen T., and Olsen M. H.
- Abstract
To assess whether anthropometric measures (body mass index [BMI], waist-hip ratio [WHR], and estimated fat mass [EFM]) are independently associated with major adverse cardiovascular events (MACE), and to assess their added prognostic value compared with serum total-cholesterol. The study population comprised 109,509 individuals (53% men) from the MORGAM-Project, aged 19–97 years, without established cardiovascular disease, and not on antihypertensive treatment. While BMI was reported in all, WHR and EFM were reported in ∼52,000 participants. Prognostic importance of anthropometric measurements and total-cholesterol was evaluated using adjusted Cox proportional-hazards regression, logistic regression, area under the receiver-operating-characteristic curve (AUCROC), and net reclassification improvement (NRI). The primary endpoint was MACE, a composite of stroke, myocardial infarction, or death from coronary heart disease. Age interacted significantly with anthropometric measures and total-cholesterol on MACE (P ≤ 0.003), and therefore age-stratified analyses (<50 versus ≥ 50 years) were performed. BMI, WHR, EFM, and total-cholesterol were independently associated with MACE (P ≤ 0.003) and resulted in significantly positive NRI when added to age, sex, smoking status, and systolic blood pressure. Only total-cholesterol increased discrimination ability (AUCROC difference; P < 0.001). In subjects < 50 years, the prediction model with total-cholesterol was superior to the model including BMI, but not superior to models containing WHR or EFM, while in those ≥ 50 years, the model with total-cholesterol was superior to all models containing anthropometric variables, whether assessed individually or combined. We found a potential role for replacing total-cholesterol with anthropometric measures for MACE-prediction among individuals < 50 years when laboratory measurements are unavailable, but not among those ≥ 50 years.
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- 2022
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