Search

Your search keyword '"Gregoretti B"' showing total 1 results
Start Over Author "Gregoretti B" Publication Year Range Last 3 years

Refine your results

1 results on '"Gregoretti B"'

1. A urokinase-associated outbreak of Ralstonia mannitolilytica bloodstream infections in haemodialysis patients in north-eastern Italy, January to April 2023.

Author

Fabricci M, Trinca A, Talotti L, Busetti M, Fotakis EA, Merakou C, Koncan R, Ghiotti A, Negri C, Di Maso V, Bosco M, Antonelli A, Coppi M, Rossolini GM, Giuliani C, Scarpis E, Gregoretti B, Licastro D, Luzzati R, and Costantino V

Subjects
Humans, Urokinase-Type Plasminogen Activator genetics, Urokinase-Type Plasminogen Activator therapeutic use, Renal Dialysis adverse effects, Disease Outbreaks, Gram-Negative Bacterial Infections diagnosis, Gram-Negative Bacterial Infections drug therapy, Gram-Negative Bacterial Infections epidemiology, Sepsis epidemiology
Abstract

An outbreak of Ralstonia mannitolilytica bloodstream infections occurred in four hospitals in north-eastern Italy, involving 20 haemodialysis patients with tunnelled central vascular catheter access. We identified as the outbreak source a batch of urokinase vials imported from India contaminated with R. mannitolilytica. Whole genome sequences of the clinical and urokinase strains were highly related, and only urokinase-treated patients were reported with R. mannitolilytica infections (attack rate = 34%; 95% confidence interval: 22.1-47.4). Discontinuation of the contaminated urokinase terminated the outbreak.

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results