1. Education, employment, and income among people living with cystic fibrosis across three decades – A matched cohort study using Danish health registries.
- Author
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Jensen, Camilla Bjørn, Jensen, Kristoffer Jarlov, Pressler, Tacjana, Katzenstein, Terese L., Skov, Marianne, Qvist, Tavs, Olsen, Mette Frahm, Jeppesen, Majbritt, Jensen-Fangel, Søren, Olesen, Hanne Vebert, Reuter, Simon Bertram, Pedersen, Hans Kristian Råket, Wang, Joanna Nan, Michalopoulos, Steven, McGarry, Lisa, Wöhling, Heike, Petersen, Janne, and Jimenez-Solem, Espen
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TYPE 1 diabetes , *LABOR supply , *INCOME , *CYSTIC fibrosis , *DIABETES in children - Abstract
• The past developments in cystic fibrosis (CF) treatment warrant a long-term description of the societal impact of the disease. Understanding how societal impact of CF has developed is important to inform health policies to prevent inequalities and secure the right to equal opportunities in life. • The present study describes the development in key socioeconomic factors across 30 years in people living with CF (pwCF) in Denmark, compared with the general population and an early onset chronic disease population. • The educational level of pwCF was similar to the two comparator cohorts indicating successful mitigation of negative effects. However, pwCF were less often in employment and more often permanently outside the labor force than the comparator cohorts. • PwCF had similar or higher personal or household income than the comparator cohorts. • The societal profile of the CF cohort and the comparator cohorts became more alike during the study period. Past and ongoing advancements in cystic fibrosis (CF) care warrant long-term analysis of the societal impact of the condition. This study aims to evaluate changes in key socioeconomic factors across three decades among people living with CF (pwCF), compared with both the general population and an early-onset chronic disease population. This nationwide, registry-based, matched cohort study included all pwCF ≥ 18 years in Denmark in the years 1990, 2000, 2010, and 2018. Each person living with CF was matched to five individuals in the general population and five individuals living with type 1 diabetes or juvenile arthritis based on age, sex, and municipality. The Danish adult CF population increased nearly fourfold from 88 in 1990 to 331 in 2018, and mean age increased by ten years. The educational level of pwCF was similar to the two comparator cohorts, while pwCF were less often in employment and more often permanently outside the labor force. Personal and household income levels of the CF cohort were higher than those of the comparator cohorts. The disadvantage in employment for pwCF remained, but, over time, the societal profiles of the one-year CF cohorts increasingly converged with those of the comparator cohorts, indicative of improved clinical management, extended life expectancy, and the supportive role of the Danish welfare system in reducing health inequalities. Further research should be done to evaluate the effects of the newly introduced modulator therapies on employment, considering the broader societal impact and impact on quality of life. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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