Search

Background: Snake bites are a major public health concern around the world, particularly in tropical and subtropical areas. The laboratory investigations done provide vital and crucial diagnostic markers which can help with the management of complications. This study was taken up to laboratory investigation profile of snake bite victims presenting to Dr.Vitthalrao Vikhe Patil Pravara Rural Hospital, Loni, India. Methodology: All cases of snake bite of age group of more than 12yrs of both genders were enrolled for the study. (n=83). Individuals with snakebite patient admitted in PRH, Loni was interviewed with a structured proforma. Data obtained in history, clinical examination and follow-up preformed were entered in excel sheet and subjected to appropriate study analysis by using SPSS software. Results: In present Study, various categories of duration of onset of symptoms at presentation <5 hours (14.67) showed higher Prothrombin time followed by 5-10 hours duration (13.51), >15 hours (13.38) and 10-15 hours (13.202) .In present study, INR showed non significant results among any duration category of symptoms at presentation. Conclusion: Acute kidney injury is one of the most significant complications developing due to snake bite. Factors associated with AKI that are routinely examined in the laboratory are bite to prolonged bleeding time, prolonged prothrombin time and hematuria. Serum Urea, serum creatine and platelet count had no significant correlation with snakebite. [ABSTRACT FROM AUTHOR]

Introduction: Considering the cost of Anti-Snake Venom (ASV) and irregularity in its supply, there is often a need to curtail doses of ASV, despite guidelines for management of snake bite. During June 2013 to September 2013, when ASV was in short supply, our institutional committee reviewed the overall hospital statistics of snake bite cases as well as scientific literature and formulated a working modified protocol that used low dose of ASV in snake bite cases. Aim: To retrospectively analyse and compare the modified ASV protocol versus conventional ASV protocol with respect to outcome, number of ASV vials required, duration of stay in the hospital/ ICU, and additional supportive interventions needed. Materials and Methods: This was a retrospective study conducted at a tertiary care teaching hospital, Maharashtra, India. Hospital records of inpatients admitted for snake bite during June 2013 to September 2013 (since introduction of the modified protocol) as well as during June 2012 to September 2012, (when patients received conventional protocol-historical controls) were retrospectively analysed to assess the number of ASV vials received by the patients during the stay, need for supportive therapy, duration of stay and outcome of the patients. Results: There was a significant reduction in average number of ASV vials per patient, required vide the modified protocol compared to their historical controls (10.74±0.95 vs 28.17±2.75 p

Introduction: Considering the cost of Anti-Snake Venom (ASV) and irregularity in its supply, there is often a need to curtail doses of ASV, despite guidelines for management of snake bite. During June 2013 to Sept 2013, when ASV was in short supply, our institutional committee reviewed the overall hospital statistics of snake bite cases as well as scientific literature and formulated a working modified protocol that used low dose of ASV in snake bite cases. Aim: To retrospectively analyse and compare the modified ASV protocol versus conventional ASV protocol with respect to outcome, number of ASV vials required, duration of stay in the hospital/ICU, and additional supportive interventions needed. Materials and Methods: This was a retrospective study conducted at a tertiary care teaching hospital, Maharashtra, India. Hospital records of inpatients admitted for snake bite during June 2013 to September 2013 (since introduction of the modified protocol) as well as during June 2012 to September 2012, (when patients received conventional protocol-historical controls) were retrospectively analysed to assess the number of ASV vials received by the patients during the stay, need for supportive therapy, duration of stay and outcome of the patients. Results: There was a significant reduction in average number of ASV vials per patient, required vide the modified protocol compared to their historical controls (10.74+0.95 Vs 28.17+2.75 p<0.001). There was no significant difference in outcome, need for dialysis, fresh frozen plasma requirement, need for ICU stay and duration of hospitalization of snake bite patients. Yet, the average cost of management of each patient reduced by approximately 11974.41 INR per treated patient, based on the requirement of ASV. Conclusion: The modified ASV protocol used in this study is more cost effective as compared to the conventional protocol, deserves prospective evaluation and may be followed at least during prime time of scarcity of ASV. [ABSTRACT FROM AUTHOR]