1. Investigating effectiveness of adherence of long-acting bronchodilator in chronic obstructive pulmonary disease with influenza infection
- Author
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Kuang-Ming Liao, Hsiao-Feng Huang, Yi-Ju Chen, Chuan-Wei Shen, Chung-Yu Chen, and Yaw-Bin Huang
- Subjects
Chronic obstructive pulmonary disease ,Influenza ,Adherence ,Science (General) ,Q1-390 ,Social sciences (General) ,H1-99 - Abstract
Objectives: Long-acting bronchodilators are important treatments for chronic obstructive pulmonary disease (COPD) and adequate medication adherence decreases COPD exacerbations, especially in reducing the hazard of influenza infection. Therefore, the study aim was to evaluate adherence of long-acting bronchodilator treatment and the risk of influenza in patients with COPD. Methods: This retrospective nested case-control study included patients with newly diagnosed COPD from 2012 to 2018. Cases with influenza infection were defined and matched to 2 randomly selected controls. The influenza infection date was the index date. Conditional logistic regressions were used to estimate odds ratios of influenza from proportion of days covered (PDC) of long-acting bronchodilators measured in one year before the index date. Adherence was divided into high adherence (PDC ≥80 %) and low adherence (PDC
- Published
- 2024
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