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A study conducted by Yamagata University School of Medicine in Japan explored the use of electroconvulsive therapy (ECT) for managing psychiatric symptoms and Parkinsonism in patients with dementia with Lewy bodies (DLB) and mild cognitive impairment (MCI) with Lewy bodies. The retrospective study found that ECT significantly improved psychotic symptoms and Parkinsonism, with minimal adverse effects on cognitive function. The researchers concluded that further large-scale studies are needed to establish the effectiveness and safety of ECT for DLB and MCI with LB. [Extracted from the article]

A recent study conducted at Yamagata University in Japan explored the relationship between pro-coagulant and inflammatory responses in monocytes in patients with preeclampsia (PE). The research found that markers of pro-coagulant and inflammatory responses were elevated in PE compared to normal pregnancy, and that low-dose aspirin could potentially mitigate these responses. The study suggests that a loss of tuning of both pro-coagulant and inflammatory responses in monocytes may contribute to the pathology of PE, providing insights for prediction and preventive treatment. [Extracted from the article]

A study conducted at the Yamagata Prefectural Institute of Public Health in Japan focused on Legionnaires' Disease caused by Legionella pneumophila serogroup 13 (SG13). The researchers developed a modified multiplex PCR system to improve the diagnosis of non-SG1 pneumonia cases, which are often difficult to diagnose in laboratory settings. The findings suggest that this new method could enhance the identification of Legionnaires' Disease caused by L. pneumophila SG13 and other serogroups, potentially leading to more accurate diagnoses and treatments. [Extracted from the article]

A study conducted at Yamagata University Hospital in Japan examined the impact of Helicobacter pylori infection on gastric endoscopic findings in non-eosinophilic esophagitis eosinophilic gastrointestinal diseases. The research found that gastric ulcers in patients with non-EoE EGIDs should be considered in the differential diagnosis of idiopathic peptic ulcers. The study analyzed the prevalence and distribution of gastric endoscopy findings in patients with non-EoE EGIDs, highlighting the influence of atrophic gastritis as an indicator of H. pylori infection. [Extracted from the article]

A study conducted at Yamagata University in Japan analyzed the correlation between pelvic floor movement and prostate displacement in image-guided radiotherapy for prostate cancer. The research found statistically significant correlations between the displacement of the prostate and pelvic floor in certain directions, indicating that pelvic floor muscle tension may impact the accuracy of radiotherapy. The study suggests the importance of ensuring consistent pelvic floor muscle tension during treatment to improve the precision of radiotherapy for prostate cancer patients. This research has been peer-reviewed and provides valuable insights into optimizing treatment strategies for prostate cancer patients undergoing radiotherapy. [Extracted from the article]

A recent study conducted at Yamagata University in Japan focused on developing flexible X-ray shielding composites using glycerol, starch, and barium sulfate (BaSO4) as X-ray active fillers. The research explored the use of tannic acid (TA) for surface modification of the BaSO4 to improve the composite's X-ray shielding properties without compromising flexibility. The study found that the addition of TA facilitated the formation of hydrogen bonds, enhancing the composites' elongation and changing the fracture behavior from brittle to ductile. This environmentally friendly approach to developing biodegradable radiation shielding materials holds promise for future applications in the field of health and medicine. [Extracted from the article]

A recent study conducted by Yamagata University in Japan has found that combined immunotherapy may improve dysautonomia, including vocal cord palsy, in patients with anti-IgLON5 disease. Dysautonomia is a major symptom of this disease and is typically difficult to treat with immunotherapy. The study reported a case of a patient with anti-IgLON5 disease who experienced various autonomic failures, including vocal cord palsy, and saw improvement in their symptoms after receiving combined immunotherapy. This research suggests that combined immunotherapy may be a potential treatment option for dysautonomia in anti-IgLON5 disease. [Extracted from the article]

A study conducted at Yamagata University in Japan explored the effectiveness of inter-hospital heart team conferences in facilitating outpatient cardiac rehabilitation (CR) programs for patients with cardiovascular disease. The study divided 145 patients into two groups: a collaborative group that received outpatient care at a university hospital and outpatient CR at different hospitals, and a same-hospital group that received both outpatient care and outpatient CR at the same hospital. Both groups showed significant improvements in various cardiovascular measures, and there was no significant difference in prognosis between the two groups. The researchers concluded that regular inter-hospital heart team conferences are useful for promoting collaboration among outpatient CR programs. [Extracted from the article]

The article presents new insights into Citrin deficiency (CD), a hereditary disorder linked to mutations in the SLC25A13 gene that affects various bodily functions. Topics discussed include the role of citrin in glycolysis, the effectiveness of medium-chain triglyceride (MCT) supplements for treatment, and dietary recommendations for improving patient outcomes and preventing irreversible damage.

A recent study conducted at Yamagata University in Japan has revealed new findings in the field of artificial skin. The researchers have developed a flexible pressure sensor using electret-type particles with self-power-generating properties. This sensor has an ultrafast response time and can detect tactile signals in both humans and robots. The study highlights the potential applications of high-performance flexible sensing technology in the future. The research was funded by various organizations and has been peer-reviewed. [Extracted from the article]

A recent study conducted in Yamagata, Japan, explored the clinical characteristics and genetic factors associated with familial intraductal papillary mucinous neoplasm (IPMN) and pancreatic cancer. The study focused on a 58-year-old woman with multifocal IPMN and a family history of the condition. Genetic analysis revealed a missense variant in the MSH6 gene, which was also present in the patient's father. The study suggests a possible genetic factor for the development of familial IPMN and provides interesting clinicopathological findings. Further research is needed to better understand the relationship between genetic factors and pancreatic cancer. [Extracted from the article]

A report from Yamagata University in Japan discusses the importance of heme biosynthesis for cancer cell survival and mitochondrial function after exposure to X-ray radiation. The study found that X-ray radiation increased heme biosynthesis activity and cellular heme content. Inhibition of heme biosynthesis sensitized cancer cells to radiation and resulted in mitochondrial dysfunction, leading to cellular ATP depletion and increased radiosensitivity. The research concludes that heme biosynthesis is crucial for cell survival and mitochondrial oxidative phosphorylation after X-ray irradiation. [Extracted from the article]

A recent study conducted at Yamagata University in Japan examined the use of pulmonary function tests for diagnosing respiratory diseases, such as chronic obstructive pulmonary disease (COPD). The study found that these tests are not typically performed during annual health checkups in Japan, which hinders early diagnosis. The researchers interviewed 669 participants and performed pulmonary function tests, finding that 141 participants had pulmonary dysfunction and 115 had obstructive pulmonary dysfunction. The study concluded that individuals with obstructive pulmonary dysfunction can be efficiently identified by considering age, smoking habits, and respiratory symptoms, even if pulmonary function tests cannot be performed for all individuals during health checkups. [Extracted from the article]

A study conducted by Yamagata University in Japan aimed to examine the relationship between obesity and back pain in older populations. The researchers analyzed data from 6,868 participants and found that weight gain increased the risk of back pain, while weight loss reduced the risk. The study also found that the influence of obesity on back pain varied depending on muscle strength. These findings suggest that maintaining a healthy weight and muscle strength can help prevent back pain in older adults. [Extracted from the article]

A report from Yamagata University in Japan discusses research on radiation shielding materials using barium sulfate (BaSO4) and multiwalled carbon nanotubes (MWCNTs). The researchers found that by modifying the surface of BaSO4 with MWCNTs through electrostatic interaction, they were able to improve the interfacial adhesion and mechanical properties of the resulting composites. The addition of MWCNTs did not affect the x-ray shielding performance of the composites. This research provides new information on improving the interface of polymer composites for potential applications in the field of medical imaging. [Extracted from the article]

A recent study conducted at Yamagata University in Japan has presented a modified method of thoracoscopic S9 segmentectomy for lung surgery. The traditional method involves dividing the intersegmental plane between the superior and anterior segments, whereas the new technique focuses on dissection along the intersegmental veins. This modified approach offers advantages such as avoiding additional parenchymal splitting and being applicable in cases with an incomplete interlobar fissure. The research has been peer-reviewed and published in The Annals of Thoracic Surgery. For more information, interested individuals can contact the authors or access the article through the provided DOI link. [Extracted from the article]

Researchers from Yamagata University in Japan have developed a new dental biomaterial called CNC@HAp/CS, which is a hybrid composite of cellulose nanocrystals (CNCs), hydroxyapatite (HAp), and chitosan (CS). This material has improved hydrophobic properties and can promote remineralization, making it suitable for dental restorative applications. The researchers confirmed the successful composition of CNC@HAp/CS and observed the formation of a HAp layer through remineralization after immersion in artificial saliva. This research suggests that CNC@HAp/CS has self-healing properties and can be used as a dental material. [Extracted from the article]

A study conducted by researchers at Yamagata University in Japan has found that growth differentiation factor-15 (GDF15), a stress-response cytokine belonging to the transforming growth factor-beta superfamily, is associated with cardiovascular disease and its outcomes in patients with lower extremity artery disease (LEAD). The study measured serum GDF15 levels in 200 LEAD patients before their initial endovascular therapy and found that higher levels of GDF15 were associated with increased rates of all-cause mortality and thrombotic and bleeding events. The researchers concluded that serum GDF15 could be a potentially useful marker for tracking clinical outcomes, specifically for thrombotic and bleeding events, in LEAD patients. [Extracted from the article]

A study conducted at Yamagata Prefectural Central Hospital in Japan explored the use of nivolumab therapy in a 75-year-old man with lung cancer and IgG4-related disease (IgG4-RD). The patient was treated with nivolumab and low-dose prednisolone for 15 months, during which time the IgG4-RD did not relapse and no adverse events occurred. The researchers concluded that anti-programmed cell death protein-1 antibody (nivolumab) may be safely used in lung cancer patients with IgG4-RD, alongside low-dose steroids. This research has been peer-reviewed and published in Internal Medicine. [Extracted from the article]

A recent study conducted in Japan examined the relationship between food group-specific intake and depression among local government employees. The study surveyed 503 workers and found that men with low intake of eggs and women with low or moderate intake of other vegetables and eggs had higher odds of experiencing depression. The researchers concluded that the intake of eggs in men and eggs and vegetables in women may be related to depression. This study provides valuable insights into the potential impact of diet on mental health. [Extracted from the article]

A study conducted by Yamagata University in Japan examined the association between hypokalemia (low potassium levels) and kidney function in patients with heart failure with preserved ejection fraction (HFpEF). The researchers found that hypokalemia was significantly associated with renal tubular damage, preserved kidney function, and plasma volume expansion. Patients with hypokalemia also had a higher rate of heart failure-related events compared to those without hypokalemia. The study concludes that hypokalemia is a risk factor for heart failure-related events in patients with HFpEF. [Extracted from the article]

Researchers at Yamagata University in Japan have conducted a study on robotic-assisted thoracic surgery (RATS) and specifically focused on the use of dual-portal RATS (DRATS) as a reduced port approach. The study reviewed data from 20 patients who underwent anatomical lung resections via DRATS and found that there were no conversions to thoracotomy or need for extra ports. The procedure was deemed safe and feasible, with minimal postoperative complications and low pain levels. The researchers believe that DRATS could be a preliminary step towards the future use of uniportal RATS (URATS). [Extracted from the article]

A recent study conducted at Yamagata Prefectural Central Hospital in Japan has explored the use of transbronchial lung cryobiopsy (TBLC) with an ultrathin cryoprobe and guide sheath (GS) for diagnosing pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma. MALT lymphoma is a rare and difficult-to-diagnose form of cancer. The study found that TBLC with a GS is a safe and effective method for obtaining larger biopsy specimens, leading to a more accurate diagnosis of pulmonary MALT lymphoma. The technique proved particularly useful when histopathological diagnosis alone was inconclusive. No complications were reported during the procedure. [Extracted from the article]

Researchers from Yamagata University in Japan have developed a new treatment for severe intractable Bell's palsy, a condition that affects the facial nerve. The treatment involves using minimally invasive transcanal endoscopic ear surgery (TEES) to deliver basic fibroblast growth factor (bFGF) to the damaged nerve. In a study, the endoscopic salvage treatment group achieved a significantly higher rate of complete recovery compared to the control group that received high dose steroid treatment only. The researchers concluded that bFGF delivered via TEES shows promise as a new treatment for Bell's palsy without the risks associated with facial nerve decompression surgery. [Extracted from the article]

Researchers at Yamagata University in Japan have reported a case of a patient with anti-ganglioside antibodies showing multiple cranial nerve palsies, which were detected on gadolinium-enhanced magnetic resonance imaging (MRI). The patient had various neurological symptoms, including bilateral ophthalmoplegia, facial nerve palsies, dysarthria, dysphagia, and dysesthesia in both hands. Treatment with intravenous immunoglobulin improved some symptoms but worsened the facial nerve palsies, while high-dose methylprednisolone therapy improved the facial nerve palsies and gadolinium enhancement of the cranial nerves. This is the first case to track changes in gadolinium enhancement of cranial nerves on MRI in a patient with anti-ganglioside antibodies and multiple cranial nerve palsies. [Extracted from the article]

A recent study conducted at the National Cancer Center in Yamagata, Japan has provided new insights into hematopoiesis, the process of blood cell formation. The research focuses on the role of the Moz/MLL-mediated transcriptional activation system in maintaining the balance between self-renewing stem cells and nonstem cells in the blood system. Mutations in transcriptional regulators can lead to aberrant self-renewal and leukemia. The study explores the functions of the Moz/MLL-mediated transcriptional activation system and its involvement in promoting self-renewal. This research has been peer-reviewed and published in the FEBS Journal. [Extracted from the article]

A recent study conducted by Yamagata University in Japan aimed to evaluate the clinical outcomes of dental implant prosthetic rehabilitation after bone graft at the anterior mandible/maxilla based on oral health-related quality of life (OHRQOL) in young and middle-aged patients. The study included 11 patients who received bone grafts and dental implant surgery. The results showed that dental implant prosthetic rehabilitation improved OHRQOL, with significant improvements in domain scores and total scores for most items. The study suggests that bone grafts and dental implant prosthetic rehabilitation can effectively resolve oral health problems and benefit both patients and medical professionals in treatment planning and informed consent. [Extracted from the article]

Yamagata, Japan, Asia, Autoimmune Diseases and Conditions, Autoimmune Hepatitis, Autoimmunity, Digestive System Diseases and Conditions, Epidemiology, Gastroenterology, Health and Medicine, Hepatitis, Immunology, Infectious Diseases and Conditions, Liver Diseases and Conditions Keywords: Yamagata; Japan; Asia; Autoimmune Diseases and Conditions; Autoimmune Hepatitis; Autoimmunity; Digestive System Diseases and Conditions; Epidemiology; Gastroenterology; Health and Medicine; Hepatitis; Immunology; Infectious Diseases and Conditions; Liver Diseases and Conditions EN Yamagata Japan Asia Autoimmune Diseases and Conditions Autoimmune Hepatitis Autoimmunity Digestive System Diseases and Conditions Epidemiology Gastroenterology Health and Medicine Hepatitis Immunology Infectious Diseases and Conditions Liver Diseases and Conditions 318 318 1 10/24/23 20231023 NES 231023 2023 OCT 23 (NewsRx) -- By a News Reporter-Staff News Editor at Hepatitis Weekly -- Investigators publish new report on Autoimmune Diseases and Conditions - Autoimmune Hepatitis. [Extracted from the article]

Keywords: Yamagata; Japan; Asia; Food Safety; Science EN Yamagata Japan Asia Food Safety Science 293 293 1 09/11/23 20230914 NES 230914 2023 SEP 14 (NewsRx) -- By a News Reporter-Staff News Editor at Food Weekly News -- New research on Science is the subject of a report. Keywords for this news article include: Asia, Japan, Science, Yamagata, Food Safety. [Extracted from the article]

Keywords: Yamagata; Japan; Asia; Cardiology; Cardiovascular Diseases and Conditions; Cytokines; Growth Differentiation Factor 15; Growth Differentiation Factors; Health and Medicine; Heart Disease; Heart Disorders and Diseases; Heart Failure; Intercellular Signaling Peptides and Proteins; Peptides; Proteins; Risk and Prevention; TGF-beta Superfamily Proteins EN Yamagata Japan Asia Cardiology Cardiovascular Diseases and Conditions Cytokines Growth Differentiation Factor 15 Growth Differentiation Factors Health and Medicine Heart Disease Heart Disorders and Diseases Heart Failure Intercellular Signaling Peptides and Proteins Peptides Proteins Risk and Prevention TGF-beta Superfamily Proteins 606 606 1 09/11/23 20230911 NES 230911 2023 SEP 11 (NewsRx) -- By a News Reporter-Staff News Editor at Cardiovascular Week -- Investigators publish new report on Heart Disorders and Diseases - Heart Failure. According to the news editors, the research concluded: "Serum GDF15 concentrations were associated with HF severity and clinical outcomes, indicating that GDF15 could provide additional clinical information to track the health status of patients with HF.". [Extracted from the article]

Japan, Asia, Blood Proteins, Cancer, Carcinomas, Cell Proliferation, Globins, Health and Medicine, Hemoglobins, Kidney, Nephrology, Oncology, Proteins, Yamagata Keywords: Yamagata; Japan; Asia; Blood Proteins; Cancer; Carcinomas; Cell Proliferation; Globins; Health and Medicine; Hemoglobins; Kidney; Nephrology; Oncology; Proteins EN Yamagata Japan Asia Blood Proteins Cancer Carcinomas Cell Proliferation Globins Health and Medicine Hemoglobins Kidney Nephrology Oncology Proteins 1395 1395 1 08/28/23 20230829 NES 230829 2023 AUG 28 (NewsRx) -- By a News Reporter-Staff News Editor at Clinical Oncology Week -- A new study on Oncology - Carcinomas is now available. [Extracted from the article]

The news reporters obtained a quote from the research from Yamagata University, "However, whether ABSI is a risk factor for AD-related mortality in the general population remains unclear. Keywords: Yamagata; Japan; Asia; Abdominal Obesity; Health and Medicine; Nutritional and Metabolic Diseases and Conditions; Risk and Prevention EN Yamagata Japan Asia Abdominal Obesity Health and Medicine Nutritional and Metabolic Diseases and Conditions Risk and Prevention 686 686 1 08/14/23 20230814 NES 230814 2023 AUG 14 (NewsRx) -- By a News Reporter-Staff News Editor at Cardiovascular Week -- Investigators discuss new findings in Nutritional and Metabolic Diseases and Conditions - Abdominal Obesity. Yamagata, Japan, Asia, Abdominal Obesity, Health and Medicine, Nutritional and Metabolic Diseases and Conditions, Risk and Prevention. [Extracted from the article]

For more information on this research see: A Phase I/ii Study of 10-min Dosing of Bendamustine Hydrochloride (Rapid Infusion Formulation) In Patients With Previously Untreated Indolent B-cell Non-hodgkin Lymphoma, Mantle Cell Lymphoma, or Relapsed/refractory Diffuse Large B-cell Lymphoma In Japan. Keywords: Yamagata; Japan; Asia; Alkylating Agents; Antineoplastics; B-Cell Lymphoma; Bendamustine Hydrochloride; Bendamustine Therapy; Cancer; Clinical Research; Clinical Trials and Studies; Drugs and Therapies; Health and Medicine; Hematology; Immunoproliferative Disorders; Large B-Cell Lymphoma; Lymphatic Diseases and Conditions; Lymphoma; Lymphoproliferative Disorders; Mantle Cell Lymphoma; Non-Hodgkin Lymphoma; Oncology; Pharmaceuticals EN Yamagata Japan Asia Alkylating Agents Antineoplastics B-Cell Lymphoma Bendamustine Hydrochloride Bendamustine Therapy Cancer Clinical Research Clinical Trials and Studies Drugs and Therapies Health and Medicine Hematology Immunoproliferative Disorders Large B-Cell Lymphoma Lymphatic Diseases and Conditions Lymphoma Lymphoproliferative Disorders Mantle Cell Lymphoma Non-Hodgkin Lymphoma Oncology Pharmaceuticals 758 758 1 06/26/23 20230626 NES 230626 2023 JUN 26 (NewsRx) -- By a News Reporter-Staff News Editor at Clinical Trials Week -- Current study results on Oncology - Mantle Cell Lymphoma have been published. [Extracted from the article]

Keywords: Yamagata; Japan; Asia; Alkaline Phosphatase; Bone Research; Enzymes and Coenzymes; Health and Medicine; Light Metals; Magnesium; Mineral Metabolism; Phosphoric Monoester Hydrolases; Risk and Prevention EN Yamagata Japan Asia Alkaline Phosphatase Bone Research Enzymes and Coenzymes Health and Medicine Light Metals Magnesium Mineral Metabolism Phosphoric Monoester Hydrolases Risk and Prevention 4053 4053 1 06/05/23 20230609 NES 230609 2023 JUN 9 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Investigators discuss new findings in Enzymes and Coenzymes - Phosphoric Monoester Hydrolases. Blood samples from the umbilical cords and infants were analysed with respect to mineral metabolism, intact parathyroid hormone (iPTH) level, and alkaline phosphatase (ALP) level. [Extracted from the article]