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Residual anionic polyacrylamide in polymer-flooding oil production wastewater results in the formation of a thermodynamically stable system. In this study, the effects of three different types of medicaments, namely, cationic, anionic and nonionic agents, in dynamic treatments, such as adding a position, dosage and combined processes of chemical addition, on the oil removal rate of sewage were examined. In the treatment with a single agent, the oil removal rate of the cationic agent CQY-1 and the nonionic agent CHF-2 was ≥ 97.8%. The charge characteristics of different ionic agents for the combined dosing treatment indicated that the oil removal rate was better than that of a single agent; the combined dosing ratio was 50 mg/L CHP-1 and 50 mg/L CHP-2. At 80 mg/L CQY-1, the oil removal rate of the dynamic process was ≥ 98.8%, and the dosage of CQY-1 was reduced from 200 mg/L to 50–150 mg/L, which corresponded to a decrease of 25.0%–75.0%. Therefore, the combined dosing process effectively reduced the single dosage.

The current study was conducted to evaluate the effect of parity and days in milk on milk yield and milk production traits and their correlation with β-hydroxybutyrate (BHB) concentrations in milk of Chinese tropic Holstein dairy cows which are adapted to a humid subtropical climate in central China. About 3055 milking records of Holstein cows were obtained from three farms in the hot region in the center of China. The records were classified according to parity to 4 categories: first parity, second parity, third parity, and greater than third parity. According to days in milk, there were 4 groups, first group from (1-100 days), second group from (101-200 days), third group from (201-305 days), and fourth group (>305 days). Milk samples collected between April and November 2019 from the three farms were routinely checked for milk components including BHB using mid-infrared spectroscopy a MilkoScan FT+ (Foss, Hillerod, Denmark). Data were analyzed by multivariate analysis of variance (generalized linear model, GLM). Pearson's correlation coefficients were used to measure the correlation between SCC and BHB with milk yield and milk production traits. Results showed the significant effect of parity and days in milk on milk yield and milk production traits. There was a negative effect of parity and days in milk on milk quality, with increasing parity and days in milk being associated with higher somatic cell count (SCC) (P

Previous studies have shown that postoperative cognitive dysfunction (POCD) is related to multiple factors including age, postoperative trauma, inflammation, postoperative pain, and anesthesia, among which postoperative pain is thought to play an important role in the development of POCD. This review summarizes the recent findings in the study of the role of postoperative pain in the pathogenesis of POCD in light of nerve injuries, neural remodeling and stress, and the progress in the prevention and treatment of POCD in elderly patients. It is of vital important to assess the postoperative pain and formulate adequate analgesic regimens for effective prevention and management of POCD to protect the brain functions of elderly patients.

Background: Morphine is an opioid analgesic drug often used for pain relief in cancer patients. However, there is growing evidence that morphine may modulate tumor growth, progression and metastasis. Unfortunately, the results obtained by these studies are still contradictory. Methods: In this study, we investigated the effect of morphine in human clear cell renal cell carcinoma 786-O, RLC-310 cells and whether morphine affects on tumor growth in human clear cell renal cell carcinoma 786-O, RLC-310 cells. The cell proliferation was determined by MTT assay, cell proliferation, migration and invasion assays. Immunofluorescence staining and Q-PCR was used to determine the Survivin expression. Results: It was shown that morphine enhances proliferation of 786-O, RLC-310 cells, whereas morphine promoted the growth and aggressive phenotype of 786-O and RLC-310 cells in vitro though Survivin-dependent signaling. Conclusions: Our data showed that morphine promotes RCC growth and increases RCC progression via over-expression of Survivin.