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Comparative effects of target-controlled infusion of anesthetic sufentanil and remifentanil on inflammatory factors and oxidative stress indicators in patients of colorectal cancer
- Source :
- European Journal of Inflammation, Vol 17 (2019)
- Publication Year :
- 2019
- Publisher :
- SAGE Publishing, 2019.
-
Abstract
- This study was designed to compare the recovery of target-controlled infusion of sufentanil and remifentanil in patients of colorectal cancer. In total, 104 patients were randomly divided into sufentanil and remifentanil groups. One group was given target-controlled infusion of sufentanil, while the other group received remifentanil. Inflammatory factors and oxidative stress indicators were measured at 10 min before induction of anesthesia (T1), 1 h (T2), 24 h (T3), and 72 h (T4) after surgery. Adverse reactions were also compared. The extubation and recovery time of sufentanil group were longer than remifentanil group. The levels of CRP, IL-8, and IL-4 in sufentanil group and remifentanil group increased continuously. CRP contents at T3, T4, and IL-8 and IL-4 contents at T2, T3, and T4 of remifentanil group were lower ( P
- Subjects :
- Medicine
Subjects
Details
- Language :
- English
- ISSN :
- 20587392
- Volume :
- 17
- Database :
- Directory of Open Access Journals
- Journal :
- European Journal of Inflammation
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.5de2d7094f4a4d2fbbe89633d0dfce7d
- Document Type :
- article
- Full Text :
- https://doi.org/10.1177/2058739219863288