43 results on '"Shui, Bin"'
Search Results
2. Greenhouse gas emissions benefits of the lightweight vehicle fleet in China: A dynamic fleet perspective
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Shui, Bin, Luo, Xiaowei, and Huang, Guanying
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- 2024
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3. Light-duty passenger vehicle electrification in China from 2021 to 2050 and associated greenhouse gas emissions: A dynamic fleet perspective
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Shui, Bin, Shafique, Muhammad, and Luo, Xiaowei
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- 2024
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4. Tunable bandwidth terahertz perfect absorption device based on vanadium dioxide phase transition control.
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Shui, Bin, Yi, Yingting, Ma, Can, Yi, Zao, Li, Gongfa, Zeng, Liangcai, Zeng, Qingdong, Wu, Pinghui, and Yi, Yougen
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PHASE transitions , *VANADIUM dioxide , *ABSORPTION , *IMPEDANCE matching , *ELECTRIC impedance , *VANADIUM - Abstract
Utilizing the phase transition principle of VO2, this paper presents a tunable ultra-wideband terahertz perfect absorption device with simple structure and tunability. The proposed broadband terahertz perfect absorption device is a three-layer structure with a metal reflective layer, a silicon dioxide dielectric layer and a VO2 layer from bottom to top. It was found that the terahertz perfect absorption device's absorption could be dynamically adjusted from 1.2% to 99.9% when changing from an insulated to a metallic state. With the VO2 in the metallic state, the terahertz perfect absorption device has an absorption efficiency of more than 90% in 4.00 to 10.08 THz's ultra-broadband range and near-perfect absorption is achieved in the ranges of 4.71 THz to 5.16 THz and 7.74 THz to 8.06 THz. To explain the working principle of this terahertz perfect absorption device, this paper utilizes wave interference's principle, theory of impedance matching and electric field analysis. Compared to previously reported terahertz metamaterial devices, the vanadium dioxide device proposed in this paper is significantly optimized in terms of tunable range and absorption bandwidth. In addition, the terahertz perfect absorption device is polarization insensitive and maintains good absorptivity over a wide-angle incidence range. This tunable ultra-wideband terahertz perfect absorption device could have applications in the fields of modulation, stealth devices, and thermal emission devices. [ABSTRACT FROM AUTHOR]
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- 2024
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5. Increased lipopolysaccharide content is positively correlated with glucocorticoid receptor‐beta expression in chronic rhinosinusitis with nasal polyps
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Shui‐Bin Wang, Shi‐Ming Chen, Ke‐Sheng Zhu, Bin Zhou, Long Chen, and Xiao‐Yan Zou
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chronic rhinosinusitis with nasal polyps ,Escherichia coli ,lipopolysaccharide ,Immunologic diseases. Allergy ,RC581-607 - Abstract
Abstract Introduction Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common and frequently occurring disease of the upper respiratory tract. The nasal instillation of the Gram‐negative (G−) bacterial product lipopolysaccharide (LPS) can induce not only acute sinusitis but also the development of CRSwNP in animal models. Nevertheless, the expression and distribution of LPS in patients with CRSwNP have not been investigated. And the study was to investigate the expression of LPS and its relationship with glucocorticoid receptors (GRs) in CRSwNP. Methods Multiple methods, including bacterial culture and immunohistochemistry, were used to detect and analyze nasal bacteria, plasma LPS content, and the levels of LPS and GR‐α/β, cluster of differentiation 68 (CD68), and myeloperoxidase (MPO) expression, as well as their relationship in CRSwNP. Results The number of G− bacteria and Escherichia coli (E. coli) was not significantly different between CRSwNP subjects and the controls. However, the positive rate of LPS was much higher than that of E. coli in CRSwNP subjects and was significantly higher in noneosinophilic CRSwNP subjects than in eosinophilic CRSwNP subjects. Moreover, the LPS levels were positively correlated with GR‐β but not GR‐α expression in CRSwNP. Immunofluorescence assays showed that LPS was mainly detected in CD68+ macrophages and MPO+ neutrophils, in addition to histiocytes, in CRSwNP. Conclusions Persistent LPS in CRSwNP can lead to unresolved mucosal inflammation, eventually leading to tissue remodeling and the development of CRSwNP. Our findings suggest that increased LPS content and possible resistance to glucocorticoids may be one of the important pathogenic mechanisms of G− bacteria in CRSwNP.
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- 2020
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- View/download PDF
6. Pretreatment HIV drug resistance in adults initiating antiretroviral therapy in China, 2017
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Rui-Hua Kang, Shu-Jia Liang, Yan-Ling Ma, Shu Liang, Lin Xiao, Xin-Hui Zhang, Hong-Yan Lu, Xiao-Qin Xu, Shui-Bin Luo, Xiao-Guang Sun, Lin Chen, Jian-Mei He, Guo-Hui Wu, Ling-Jie Liao, Hui Xing, Yi-Ming Shao, and Yu-Hua Ruan
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HIV ,Pretreatment drug resistance ,Transmission network ,Antiretroviral therapy ,Infectious and parasitic diseases ,RC109-216 ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background After the scale-up of antiretroviral therapy (ART) for HIV infected people, increasing numbers of patients have pretreatment drug resistance (PDR). In this study, the prevalence of PDR was evaluated in adults initiating antiretroviral therapy in China. Methods Blood samples were obtained from 1943 patients who initiated antiretroviral therapy (ART) in 2017 from 13 provinces or cities in China. Pol sequences were used to analyze drug resistance and construct transmission networks. Logistic regression model was used to estimate the potential factors associated with PDR. Results In total, 1711 eligible patients (76.0% male; 87.8% aged ≥ 25 years) were included, of which 117 (6.8%) had PDR. The highest rates of PDR were 12.2% in Liangshan Prefecture of Sichuan and 9.3 and 8.9% in Dehong and Lincang Prefecture of Yunnan. A multivariate logistic regression analysis revealed that PDR was significantly higher among intravenous drug users (adjusted Odds Ratio (aOR) = 2.64, 95% CI: 1.57–4.44) and individuals from Liangshan, Dehong, and Lincang (aOR = 2.04, 95% CI: 1.26–3.30). In total, 754 sequences were used to generate 164 transmission networks. Five transmission networks had two or three sequences containing the same mutations, two networks contained subjects from Liangshan, and one network contained subjects from Dehong. Conclusions Overall, the PDR prevalence was moderate, with a particularly high prevalence in areas with severe HIV epidemics. These results indicate the importance of continuous PDR monitoring in patients initiating antiretroviral therapy.
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- 2020
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7. A digital phase shift method for phase compensation of electronic transformer.
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Wei Wei, Han-Miao Cheng, Fan Li, Dengping Tang, and Shui-Bin Xia
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- 2018
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8. Synergistic Factor Analysis of Production-City Integration
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Jiang, Shui-bin, Shen, Jiang, Qi, Ershi, editor, Shen, Jiang, editor, and Dou, Runliang, editor
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- 2016
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9. Pretreatment HIV drug resistance in adults initiating antiretroviral therapy in China, 2017
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Kang, Rui-Hua, Liang, Shu-Jia, Ma, Yan-Ling, Liang, Shu, Xiao, Lin, Zhang, Xin-Hui, Lu, Hong-Yan, Xu, Xiao-Qin, Luo, Shui-Bin, Sun, Xiao-Guang, Chen, Lin, He, Jian-Mei, Wu, Guo-Hui, Liao, Ling-Jie, Xing, Hui, Shao, Yi-Ming, and Ruan, Yu-Hua
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- 2020
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10. Evacuation Simulation Incorporating Safety Signs and Information Sharing
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Niu, Yu, Yang, Hongyu, Fu, Jianbo, Che, Xiaodong, Shui, Bin, Zhang, Yanci, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Weikum, Gerhard, Series editor, and Zhang, Yu-Jin, editor
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- 2015
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11. A comprehensive analysis of building energy efficiency policies in China: status quo and development perspective
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Li, Jun and Shui, Bin
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- 2015
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12. A detailed view of PLGA-mPEG microsphere formation by double emulsion solvent evaporation method
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Feng, Shui-bin, Fu, De-hao, Nie, Lei, Zou, Peng, and Suo, Jin-ping / 索进平
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- 2015
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13. A novel simulation framework based on information asymmetry to evaluate evacuation plan
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Che, Xiaodong, Niu, Yu, Shui, Bin, Fu, Jianbo, Fei, Guangzheng, Goswami, Prashant, and Zhang, Yanci
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- 2015
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14. Increased lipopolysaccharide content is positively correlated with glucocorticoid receptor‐beta expression in chronic rhinosinusitis with nasal polyps
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Ke-Sheng Zhu, Shi-Ming Chen, Shui-Bin Wang, Long Chen, Xiao-Yan Zou, and Bin Zhou
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Adult ,Lipopolysaccharides ,Male ,lcsh:Immunologic diseases. Allergy ,0301 basic medicine ,Adolescent ,Lipopolysaccharide ,Immunology ,chronic rhinosinusitis with nasal polyps ,Young Adult ,03 medical and health sciences ,chemistry.chemical_compound ,Nasal Polyps ,Receptors, Glucocorticoid ,0302 clinical medicine ,Glucocorticoid receptor ,Escherichia coli ,Humans ,Immunology and Allergy ,Medicine ,Nasal polyps ,Sinusitis ,Rhinitis ,Original Research ,Cluster of differentiation ,biology ,business.industry ,CD68 ,lipopolysaccharide ,Middle Aged ,medicine.disease ,030104 developmental biology ,medicine.anatomical_structure ,chemistry ,Myeloperoxidase ,Chronic Disease ,biology.protein ,Female ,lcsh:RC581-607 ,business ,030215 immunology ,Respiratory tract - Abstract
Introduction Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common and frequently occurring disease of the upper respiratory tract. The nasal instillation of the Gram‐negative (G−) bacterial product lipopolysaccharide (LPS) can induce not only acute sinusitis but also the development of CRSwNP in animal models. Nevertheless, the expression and distribution of LPS in patients with CRSwNP have not been investigated. And the study was to investigate the expression of LPS and its relationship with glucocorticoid receptors (GRs) in CRSwNP. Methods Multiple methods, including bacterial culture and immunohistochemistry, were used to detect and analyze nasal bacteria, plasma LPS content, and the levels of LPS and GR‐α/β, cluster of differentiation 68 (CD68), and myeloperoxidase (MPO) expression, as well as their relationship in CRSwNP. Results The number of G− bacteria and Escherichia coli (E. coli) was not significantly different between CRSwNP subjects and the controls. However, the positive rate of LPS was much higher than that of E. coli in CRSwNP subjects and was significantly higher in noneosinophilic CRSwNP subjects than in eosinophilic CRSwNP subjects. Moreover, the LPS levels were positively correlated with GR‐β but not GR‐α expression in CRSwNP. Immunofluorescence assays showed that LPS was mainly detected in CD68+ macrophages and MPO+ neutrophils, in addition to histiocytes, in CRSwNP. Conclusions Persistent LPS in CRSwNP can lead to unresolved mucosal inflammation, eventually leading to tissue remodeling and the development of CRSwNP. Our findings suggest that increased LPS content and possible resistance to glucocorticoids may be one of the important pathogenic mechanisms of G− bacteria in CRSwNP., We used bacterial culture and immunohistochemistry to find that the positive rate of lipopolysaccharide (LPS) was much higher than that of Escherichia coli in chronic rhinosinusitis with nasal polyps (CRSwNP), and the LPS levels were positively correlated with glucocorticoid receptor‐β (GR‐β) expression in CRSwNP. Our findings suggest increased LPS content and possible resistance to glucocorticoids may be one of the important pathogenic mechanisms of G‐negative bacteria in CRSwNP.
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- 2020
15. 105° field of view non-contact handheld swept-source optical coherence tomography
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Ringo Ng, Shanjida Khan, Shui-Bin Ni, Michael F. Chiang, Yali Jia, J. Peter Campbell, David Huang, Yifan Jian, Thanh-Tin P. Nguyen, and Susan Ostmo
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genetic structures ,Image quality ,Computer science ,Field of view ,Image processing ,Retina ,Vertical-cavity surface-emitting laser ,law.invention ,Optics ,Optical coherence tomography ,Retinal Diseases ,law ,medicine ,Humans ,medicine.diagnostic_test ,business.industry ,Lasers ,Infant, Newborn ,equipment and supplies ,Laser ,eye diseases ,Atomic and Molecular Physics, and Optics ,Visualization ,sense organs ,business ,Mobile device ,Tomography, Optical Coherence - Abstract
We demonstrate a handheld swept-source optical coherence tomography (OCT) system with a 400 kHz vertical-cavity surface-emitting laser (VCSEL) light source, a non-contact approach, and an unprecedented single shot 105° field of view (FOV). We also implemented a spiral scanning pattern allowing real-time visualization with improved scanning efficiency. To the best of our knowledge, this is the widest FOV achieved in a portable non-contact OCT retinal imaging system to date. Improvements to the FOV may aid the evaluation of retinal diseases such as retinopathy of prematurity, where important vitreoretinal changes often occur in the peripheral retina.
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- 2021
16. Peripheral optical coherence tomography assisted by scleral depression in retinopathy of prematurity
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Shui-Bin Ni, J. P. Campbell, Michael F. Chiang, Thanh-Tin P. Nguyen, Yifan Jian, B. A. Scruggs, David Huang, Susan Ostmo, and Yali Jia
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medicine.medical_specialty ,genetic structures ,medicine.diagnostic_test ,business.industry ,Disease progression ,Retinal detachment ,Retinopathy of prematurity ,medicine.disease ,eye diseases ,Peripheral ,Optical coherence tomography ,Ophthalmology ,Medicine ,Vitreoretinal traction ,sense organs ,Stage (cooking) ,business ,Depression (differential diagnoses) - Abstract
ObjectiveTo determine whether handheld widefield optical coherence tomography (OCT) can be used to document retinopathy of prematurity (ROP) stage while using scleral depression to improve peripheral views.DesignProspective observational studyParticipantsConsecutive neonates admitted to the neonatal intensive care unit (NICU) in a single academic medical center who also met criteria for ROP screening and consented for research imaging.MethodsScleral depression was combined with widefield OCT using an investigational 400-kHz, 55-degree field of view handheld OCT during ROP screening from October 28, 2020 to March 03, 2021.Main Outcome MeasuresAcquisition of en face and B-scan imaging of the peripheral retina to objectively assess early vitreoretinal pathology, including the demarcation between vascularized and anterior avascular retina, the presence of early ridge formation, and small neovascular tufts.ResultsVarious stages of ROP were detected using a rapid acquisition OCT system. In one neonate, serial OCT imaging over a five-week period demonstrated accumulation of neovascular tufts with progression to stage 3 ROP with extraretinal fibrovascular proliferation along the ridge. Videography of this technique is included in this report for instructional purposes.ConclusionsSerial examinations using widefield OCT and scleral depression may improve detection and documentation of ROP disease progression. Earlier detection of ROP-related proliferation may prevent vitreoretinal traction, retinal detachment, and blindness.
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- 2021
17. Intranasal Administration of Lentiviral miR-135a Regulates Mast Cell and Allergen-Induced Inflammation by Targeting GATA-3.
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Yu-Qin Deng, Ya-Qi Yang, Shui-Bin Wang, Fen Li, Meng-Zhi Liu, Qing-Quan Hua, and Ze-Zhang Tao
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Medicine ,Science - Abstract
Mast cell (MC) degranulation is the foundation of the acute phase of allergic rhinitis (AR). Previously, downregulation of GATA binding protein 3 (GATA-3) was shown to suppress MC activation in an AR mouse model. Binding of microRNA-135a (miR-135a) to GATA-3 was also observed, and overexpression of this miRNA decreased GATA-3 mRNA and protein expression. However, the effects of miR-135a on MCs during AR are currently unknown. In the present study, we utilized a lentiviral (LV) vector to intranasally administer miR-135a to ovalbumin (OVA)-sensitized AR mice. Following miR-135a treatment, the total serum IgE concentration observed during AR was significantly reduced. In the nasal mucosa, the expression of T-box expressed in T cells (T-bet) was higher, whereas that of GATA-3 was lower in the AR mice following miRNA treatment. Notably, during AR, the ratio of type 1 T-helper cells (Th1) to type 2 (Th2) cells in the spleen is unbalanced, favoring Th2. However, administering miR-135a to the AR mice appeared to balance this ratio by increasing and decreasing the percentage of Th1 and Th2 cells, respectively. MiR-135a also appeared to strongly suppress the infiltration of eosinophils and MCs into the nasal mucosa, and it was specifically localized in the MCs, suggesting that its influence is modulated through regulation of GATA-3 in these cells. Additional work identifying the full therapeutic potential of miR-135a in the treatment of AR and diseases involving allergen-induced inflammation is warranted.
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- 2015
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18. Crystal structure of bis[1-(4-bromobenzyl)pyridinium] bis(1,2-dicyanoethene-1,2-dithiolato-κ2S,S′)nickelate(II)
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Dong Zeng, Shui-Bin Yang, and Zheng-Fang Tian
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crystal structure ,1-(4-bromobenzyl)pyridinium cation ,maleonitriledithiolate dianion ,square-planar bis-1,2-dithiolate complex ,Ni2+ ion ,hydrogen bonding ,Crystallography ,QD901-999 - Abstract
The asymmetric unit of the title salt, (C12H11BrN)2[Ni(C4N2S2)2], consists of one 1-(4-bromobenzyl)pyridinium cation and one half of a complex [Ni(mnt)2]2− (mnt2− is the maleonitriledithiolate dianion). The Ni2+ ion is located on an inversion centre and is coordinated by four S atoms from two mnt2− ligands, exhibiting a square-planar coordination environment. In the cation, the planes of the pyridinium and benzene rings make a dihedral angle of 69.86 (19)°. The cations and anions are alternately arranged in layers parallel to (001) and are held together by non-classical C—H...N hydrogen bonds.
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- 2014
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19. High-speed widefield handheld swept-source OCT angiography with a VCSEL light source
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Ringo Ng, Xiang Wei, Shui-Bin Ni, J. Peter Campbell, Yifan Jian, Michael F. Chiang, Susan Ostmo, David Huang, and Yali Jia
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genetic structures ,medicine.diagnostic_test ,Computer science ,Field of view ,eye diseases ,Vertical-cavity surface-emitting laser ,Light source ,Oct angiography ,Optical coherence tomography ,Hand tremor ,medicine ,Image acquisition ,sense organs ,Mobile device ,Biomedical engineering - Abstract
Optical coherence tomography (OCT) and OCT angiography (OCTA) enable noninvasive structural and angiographic imaging of the eye. Portable handheld OCT/OCTA systems are required for imaging patients in the supine position. Examples include infants in the neonatal intensive care unit (NICU) and operating room (OR). The speed of image acquisition plays a pivotal role in acquiring high quality OCT/OCTA images, particularly with the handheld system, since both the operator hand tremor and subject motion can cause significant motion artifacts. In addition, having a large field of view and the ability of real-time data visualization are critical elements in rapid disease screening, reducing imaging time, and detecting peripheral retinal pathologies. The arrangement of optical components is less flexible in the handheld system due to the limitation of size and weight. In this paper, we introduce a 400-kHz, 55-degree field of view handheld OCT/OCTA system that has overcome many technical challenges as a portable OCT system as well as a high-speed OCTA system. We demonstrate imaging premature infants with retinopathy of prematurity (ROP) in the NICU, and patients with incontinentia pigmenti (IP) in the OR using our handheld OCT system. Our design may have potential for improving the diagnosis of retinal diseases and help provide a practical guideline for designing a flexible and portable OCT system.
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- 2021
20. High-speed and widefield handheld swept-source OCT angiography with a VCSEL light source
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Shui-Bin Ni, Yali Jia, J. Peter Campbell, Ringo Ng, Xiang Wei, Yifan Jian, Michael F. Chiang, Susan Ostmo, and David Huang
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0303 health sciences ,medicine.diagnostic_test ,genetic structures ,Computer science ,Image quality ,Retinoschisis ,Image processing ,Field of view ,medicine.disease ,01 natural sciences ,Atomic and Molecular Physics, and Optics ,eye diseases ,Article ,Vertical-cavity surface-emitting laser ,010309 optics ,03 medical and health sciences ,Optical coherence tomography ,0103 physical sciences ,Angiography ,medicine ,sense organs ,Mobile device ,030304 developmental biology ,Biotechnology ,Biomedical engineering - Abstract
Optical coherence tomography (OCT) and OCT angiography (OCTA) enable noninvasive structural and angiographic imaging of the eye. Portable handheld OCT/OCTA systems are required for imaging patients in the supine position. Examples include infants in the neonatal intensive care unit (NICU) and operating room (OR). The speed of image acquisition plays a pivotal role in acquiring high-quality OCT/OCTA images, particularly with the handheld system, since both the operator hand tremor and subject motion can cause significant motion artifacts. In addition, having a large field of view and the ability of real-time data visualization are critical elements in rapid disease screening, reducing imaging time, and detecting peripheral retinal pathologies. The arrangement of optical components is less flexible in the handheld system due to the limitation of size and weight. In this paper, we introduce a 400-kHz, 55-degree field of view handheld OCT/OCTA system that has overcome many technical challenges as a portable OCT system as well as a high-speed OCTA system. We demonstrate imaging premature infants with retinopathy of prematurity (ROP) in the NICU, a patient with incontinentia pigmenti (IP), and a patient with X-linked retinoschisis (XLRS) in the OR using our handheld OCT system. Our design may have the potential for improving the diagnosis of retinal diseases and help provide a practical guideline for designing a flexible and portable OCT system.
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- 2021
21. Pretreatment HIV drug resistance in adults initiating antiretroviral therapy in China, 2017
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Lin Xiao, Xiao-Guang Sun, Lin Chen, Ling-Jie Liao, Xiaoqin Xu, Hui Xing, Shui-Bin Luo, Hongyan Lu, Ruihua Kang, Guohui Wu, Yanling Ma, Shujia Liang, Shu Liang, Jianmei He, Yiming Shao, Yuhua Ruan, and Xin-Hui Zhang
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0301 basic medicine ,Adult ,Male ,medicine.medical_specialty ,China ,Anti-HIV Agents ,030106 microbiology ,Human immunodeficiency virus (HIV) ,Pretreatment drug resistance ,HIV Infections ,Drug resistance ,Logistic regression ,medicine.disease_cause ,lcsh:Infectious and parasitic diseases ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Internal medicine ,Drug Resistance, Viral ,Prevalence ,Medicine ,Humans ,lcsh:RC109-216 ,030212 general & internal medicine ,Transmission network ,Aged ,Aged, 80 and over ,business.industry ,Transmission (medicine) ,lcsh:Public aspects of medicine ,Public Health, Environmental and Occupational Health ,HIV ,lcsh:RA1-1270 ,General Medicine ,Odds ratio ,Middle Aged ,Antiretroviral therapy ,Infectious Diseases ,Cross-Sectional Studies ,Tropical medicine ,Female ,business ,HIV drug resistance ,Research Article - Abstract
BackgroundAfter the scale-up of antiretroviral therapy (ART) for HIV infected people, increasing numbers of patients have pretreatment drug resistance (PDR). In this study, the prevalence of PDR was evaluated in adults initiating antiretroviral therapy in China.MethodsBlood samples were obtained from 1943 patients who initiated antiretroviral therapy (ART) in 2017 from 13 provinces or cities in China. Pol sequences were used to analyze drug resistance and construct transmission networks. Logistic regression model was used to estimate the potential factors associated with PDR.ResultsIn total, 1711 eligible patients (76.0% male; 87.8% aged ≥ 25 years) were included, of which 117 (6.8%) had PDR. The highest rates of PDR were 12.2% in Liangshan Prefecture of Sichuan and 9.3 and 8.9% in Dehong and Lincang Prefecture of Yunnan. A multivariate logistic regression analysis revealed that PDR was significantly higher among intravenous drug users (adjusted Odds Ratio (aOR) = 2.64, 95%CI: 1.57–4.44) and individuals from Liangshan, Dehong, and Lincang (aOR = 2.04, 95%CI: 1.26–3.30). In total, 754 sequences were used to generate 164 transmission networks. Five transmission networks had two or three sequences containing the same mutations, two networks contained subjects from Liangshan, and one network contained subjects from Dehong.ConclusionsOverall, the PDR prevalence was moderate, with a particularly high prevalence in areas with severe HIV epidemics. These results indicate the importance of continuous PDR monitoring in patients initiating antiretroviral therapy.
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- 2020
22. Increased lipopolysaccharide content is positively correlated with glucocorticoid receptor‐beta expression in chronic rhinosinusitis with nasal polyps
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Wang, Shui‐Bin, primary, Chen, Shi‐Ming, additional, Zhu, Ke‐Sheng, additional, Zhou, Bin, additional, Chen, Long, additional, and Zou, Xiao‐Yan, additional
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- 2020
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23. A digital phase shift method for phase compensation of electronic transformer
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Shui-bin Xia, Dengping Tang, Han-miao Cheng, Fan Li, and Wei Wei
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0209 industrial biotechnology ,Accuracy and precision ,Computer science ,020208 electrical & electronic engineering ,Phase error ,02 engineering and technology ,Quadrature booster ,law.invention ,020901 industrial engineering & automation ,Analog signal ,Control theory ,law ,0202 electrical engineering, electronic engineering, information engineering ,Phase compensation ,Transformer ,Instrumentation - Abstract
When sampling analog signal, the electronic transformer generally produces a fixed phase error that will compromise the measurement accuracy and require a phase shift method for correction. In this paper, we propose a digital phase shift method based on least squares fitting algorithm and derive the recursion formula of digital phase shift. The simulation has also been done to analysis its performance. The result shows that the method has high phase shift resolution and precision. By applying the method to an electronic transformer based on Rogowski coil, we have experimentally verified the feasibility and validity of the method.
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- 2017
24. Sensorless adaptive-optics optical coherence tomographic angiography
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Shui-Bin Ni, Yifan Jian, Acner Camino, Arman Athwal, Yali Jia, Pengxiao Zang, and David Huang
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Physics ,Point spread function ,0303 health sciences ,business.industry ,Image quality ,Image processing ,Field of view ,01 natural sciences ,Article ,Atomic and Molecular Physics, and Optics ,Numerical aperture ,010309 optics ,03 medical and health sciences ,Optics ,0103 physical sciences ,Figure of merit ,business ,Adaptive optics ,Image resolution ,030304 developmental biology ,Biotechnology - Abstract
Optical coherence tomographic angiography (OCTA) can image the retinal blood flow but visualization of the capillary caliber is limited by the low lateral resolution. Adaptive optics (AO) can be used to compensate ocular aberrations when using high numerical aperture (NA), and thus improve image resolution. However, previously reported AO-OCTA instruments were large and complex, and have a small sub-millimeter field of view (FOV) that hinders the extraction of biomarkers with clinical relevance. In this manuscript, we developed a sensorless AO-OCTA prototype with an intermediate numerical aperture to produce depth-resolved angiograms with high resolution and signal-to-noise ratio over a 2 × 2 mm FOV, with a focal spot diameter of 6 µm, which is about 3 times finer than typical commercial OCT systems. We believe these parameters may represent a better tradeoff between resolution and FOV compared to large-NA AO systems, since the spot size matches better that of capillaries. The prototype corrects defocus, astigmatism, and coma using a figure of merit based on the mean reflectance projection of a slab defined with real-time segmentation of retinal layers. AO correction with the ability to optimize focusing in arbitrary retinal depths – particularly the plexuses in the inner retina – could be achieved in 1.35 seconds. The AO-OCTA images showed greater flow signal, signal-to-noise ratio, and finer capillary caliber compared to commercial OCTA. Projection artifacts were also reduced in the intermediate and deep capillary plexuses. The instrument reported here improves OCTA image quality without excessive sacrifice in FOV and device complexity, and thus may have potential for clinical translation.
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- 2020
25. Depth-resolved optimization of a real-time sensorless adaptive optics optical coherence tomography
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Yali Jia, Acner Camino, Joey Huang, Ringo Ng, Yukun Guo, Shui-Bin Ni, David Huang, and Yifan Jian
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Time Factors ,genetic structures ,Image quality ,Computer science ,Zernike polynomials ,Field of view ,02 engineering and technology ,Eye ,01 natural sciences ,Deformable mirror ,010309 optics ,symbols.namesake ,Optics ,Optical coherence tomography ,0103 physical sciences ,medicine ,Humans ,Adaptive optics ,Wavefront ,medicine.diagnostic_test ,business.industry ,021001 nanoscience & nanotechnology ,eye diseases ,Atomic and Molecular Physics, and Optics ,Numerical aperture ,symbols ,sense organs ,0210 nano-technology ,business ,Tomography, Optical Coherence - Abstract
Sensorless adaptive optics optical coherence tomography (AO-OCT) is a technology to image retinal tissue with high resolution by compensating ocular aberrations without wavefront sensors. In this Letter, a fast and robust hill-climbing algorithm is developed to optimize five Zernike modes in AO-OCT with a numerical aperture between that of conventional AO and commercial OCT systems. The merit function is generated in real time using graphics processing unit while axially tracking the retinal layer of interest. A new method is proposed to estimate the largest achievable field of view for which aberrations are corrected uniformly in sensorless AO-OCT.
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- 2020
26. microRNA-299-3p inhibits laryngeal cancer cell growth by targeting human telomerase reverse transcriptase mRNA
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Chen Chen, Qiong Dai, Ze‑Zhang Tao, Man Li, Zi‑Xiong Zhang, Meng‑Yuan Dai, Shi‑Ming Chen, Lei‑Bo Zhang, and Shui‑Bin Wang
- Subjects
Cancer Research ,Down-Regulation ,Biology ,Biochemistry ,Cell Line, Tumor ,microRNA ,Genetics ,medicine ,Humans ,Telomerase reverse transcriptase ,RNA, Messenger ,3' Untranslated Regions ,Laryngeal Neoplasms ,Telomerase ,Molecular Biology ,Cell Proliferation ,Base Sequence ,Cancer ,Transfection ,Oligonucleotides, Antisense ,medicine.disease ,Molecular biology ,Reverse transcriptase ,MicroRNAs ,Real-time polymerase chain reaction ,Oncology ,Cell culture ,Cancer cell ,Cancer research ,Molecular Medicine ,Sequence Alignment ,HeLa Cells - Abstract
Aberrant microRNA (miRNA) expression has been linked to cancer development. In this study, we aimed to investigate whether the anti‑cancer effect of miRNA‑299‑3p on laryngeal cancer Hep‑2 cells is mediated through targeting human telomerase reverse transcriptase (hTERT). The expression of miR‑299‑3p in laryngeal cancer Hep‑2 cells and human osteosarcoma U2OS cells was quantified by stem‑loop‑mediated reverse transcription quantitative polymerase chain reaction. miR‑299‑3p mimic was transfected into Hep‑2 cells to induce overexpression of miR‑299‑3p. A CCK‑8 assay was performed to identify the effects of miR‑299‑3p overexpression on the proliferation of Hep‑2 cells. Western blot analysis was carried out to determine the expression of hTERT protein. A significant decrease was noted in the expression of miR‑299‑3p in Hep‑2 cells compared with that of U2OS cells (P0.05). Overexpression of miR‑299‑3p resulted in a notable inhibition of cellular proliferation (P0.05), as well as downregulation of hTERT mRNA and protein in Hep‑2 cells (P0.05). The expression of miR‑299‑3p is downregulated in human laryngeal cancer Hep‑2 cells. Overexpression of miR‑299‑3p inhibits Hep‑2 cell growth by targeting the 3'‑untranslated region of hTERT mRNA.
- Published
- 2015
27. Synergistic Factor Analysis of Production-City Integration
- Author
-
Shui-bin Jiang and Jiang Shen
- Subjects
Status assessment ,Evaluation system ,Process (engineering) ,Computer science ,Urbanization ,Factor (programming language) ,Production (economics) ,Benchmark data ,computer ,Industrial engineering ,Analysis method ,computer.programming_language - Abstract
Considering the factors of the production-city integration in the process of urbanization, we propose a model to evaluate the production-city integration process, to solve the problem of lack of dynamic status assessment. Using the factor analysis method, the model synergists four dimensional factors of production-city integration from the relative literatures and establishes an integrating evaluation system. With the benchmark data of 284 cities across our country, we verified the model with the proposed model. The results show that the guidance of the optimal factors attributes to production-city integration in the process of urbanization.
- Published
- 2016
28. Establishment of a mouse model of lipopolysaccharide-induced neutrophilic nasal polyps
- Author
-
Zulian Xi, Jingjing Huang, Hanwu Zhang, Bin Zhou, Jun Nie, Zezhang Tao, Yuqin Deng, and Shui-Bin Wang
- Subjects
0301 basic medicine ,Cancer Research ,Pathology ,medicine.medical_specialty ,Lipopolysaccharide ,Mucous membrane of nose ,Biology ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Immunology and Microbiology (miscellaneous) ,neutrophils ,medicine ,otorhinolaryngologic diseases ,Nasal polyps ,030223 otorhinolaryngology ,nasal polyps ,chronic rhinosinusitis ,lipopolysaccharide ,Interleukin ,General Medicine ,Articles ,medicine.disease ,030104 developmental biology ,chemistry ,Myeloperoxidase ,Immunology ,TLR4 ,biology.protein ,Tumor necrosis factor alpha ,Nasal Lavage Fluid - Abstract
Research has identified that gram-negative bacteria have an important role in refractory nasal polyps. In the present study, lipopolysaccharide (LPS) was used to establish a mouse model with neutrophilic nasal polyps in order to explore the effect and mechanism of LPS on the formation of neutrophilic nasal polyps in mice. A total of 5 or 10 µg of LPS was dropped into the nasal cavities of C57BL/6J mice in order to establish animal models with neutrophilic nasal polyps. Histological staining, toll-like receptor 4 (TLR4), cluster of differentiation 68 for macrophages and myeloperoxidase for neutrophil immunohistochemistry were used to observe histopathological changes in the nasal mucosa. The expression levels of cytokines, including interferon (IFN)-γ, tumor necrosis factor (TNF)-α, interleukin (IL)-4 and IL-17 in the nasal lavage fluid, were detected by ELISA. Compared with the control group, mice in the LPS groups exhibited significant mucosa epithelial cell damage and nasal polyp formation. Furthermore, TLR4+ cells, macrophages, neutrophils and significantly increased levels of IFN-γ, TNF-α, and IL-17 in the nasal lavage fluids were indicated (all P=0.008). These findings indicated that LPS is able to activate the TLR4 receptor pathway to induce the formation of neutrophilic nasal polyps in mice. Additionally, LPS administration was accompanied by a significant increase in the number of macrophages, T helper (Th) 1 and Th17-related cytokines (P=0.009, P=0.008 and P=0.008, respectively). Therefore, the present model is commensurate with the characteristics of primary nasal polyps that have been identified in the Asian population.
- Published
- 2016
29. A digital phase shift method for phase compensation of electronic transformer
- Author
-
Wei, Wei, primary, Cheng, Han-miao, additional, Li, Fan, additional, Tang, Deng-ping, additional, and Xia, Shui-bin, additional
- Published
- 2017
- Full Text
- View/download PDF
30. Intranasal Administration of Lentiviral miR-135a Regulates Mast Cell and Allergen-Induced Inflammation by Targeting GATA-3
- Author
-
Yuqin Deng, Fen Li, Ya-Qi Yang, Meng-Zhi Liu, Zezhang Tao, Shui-Bin Wang, and Qing-Quan Hua
- Subjects
Ovalbumin ,Genetic Vectors ,lcsh:Medicine ,Gene Expression ,Spleen ,Inflammation ,GATA3 Transcription Factor ,Biology ,Flow cytometry ,Th2 Cells ,Downregulation and upregulation ,medicine ,Animals ,Mast Cells ,lcsh:Science ,Administration, Intranasal ,Mice, Inbred BALB C ,Multidisciplinary ,Microscopy, Confocal ,medicine.diagnostic_test ,Reverse Transcriptase Polymerase Chain Reaction ,lcsh:R ,Lentivirus ,Degranulation ,Allergens ,Th1 Cells ,Mast cell ,Flow Cytometry ,Rhinitis, Allergic ,MicroRNAs ,Nasal Mucosa ,medicine.anatomical_structure ,Immunology ,Cancer research ,biology.protein ,lcsh:Q ,Nasal administration ,medicine.symptom ,T-Box Domain Proteins ,Research Article - Abstract
Mast cell (MC) degranulation is the foundation of the acute phase of allergic rhinitis (AR). Previously, downregulation of GATA binding protein 3 (GATA-3) was shown to suppress MC activation in an AR mouse model. Binding of microRNA-135a (miR-135a) to GATA-3 was also observed, and overexpression of this miRNA decreased GATA-3 mRNA and protein expression. However, the effects of miR-135a on MCs during AR are currently unknown. In the present study, we utilized a lentiviral (LV) vector to intranasally administer miR-135a to ovalbumin (OVA)-sensitized AR mice. Following miR-135a treatment, the total serum IgE concentration observed during AR was significantly reduced. In the nasal mucosa, the expression of T-box expressed in T cells (T-bet) was higher, whereas that of GATA-3 was lower in the AR mice following miRNA treatment. Notably, during AR, the ratio of type 1 T-helper cells (Th1) to type 2 (Th2) cells in the spleen is unbalanced, favoring Th2. However, administering miR-135a to the AR mice appeared to balance this ratio by increasing and decreasing the percentage of Th1 and Th2 cells, respectively. MiR-135a also appeared to strongly suppress the infiltration of eosinophils and MCs into the nasal mucosa, and it was specifically localized in the MCs, suggesting that its influence is modulated through regulation of GATA-3 in these cells. Additional work identifying the full therapeutic potential of miR-135a in the treatment of AR and diseases involving allergen-induced inflammation is warranted.
- Published
- 2015
31. Treatment of distal femoral fracture of Müller type A with homeopathic bidirectional-traction reduction device unite with internal fixation.
- Author
-
CUI Yan, LEI Jun, WANG Guo-qing, YANG Jun, and LIANG Shui-bin
- Published
- 2023
- Full Text
- View/download PDF
32. Characteristic expression and significance of CCL19 in different tissue types in chronic rhinosinusitis
- Author
-
You Zou, Shi‑Ming Chen, Yan Wang, Shui‑Bin Wang, Yong‑Gang Kong, Ze‑Zhang Tao, and Yu Xu
- Subjects
0301 basic medicine ,Cancer Research ,Pathology ,medicine.medical_specialty ,H&E stain ,Mucous membrane of nose ,Periodic acid–Schiff stain ,CC chemokine ligand 19 ,Masson's trichrome stain ,03 medical and health sciences ,Immunology and Microbiology (miscellaneous) ,Eosinophilic ,otorhinolaryngologic diseases ,Medicine ,Nasal polyps ,nasal polyps ,business.industry ,CD68 ,chronic rhinosinusitis ,chemokine ,General Medicine ,Articles ,Eosinophil ,respiratory system ,medicine.disease ,030104 developmental biology ,medicine.anatomical_structure ,Immunology ,eosinophils ,business - Abstract
Chronic rhinosinusitis (CRS) is a heterogeneous disease, with varying immunological and histopathological features. The CC chemokine ligand 19 (CCL19) can stimulate T cells and antigen-presenting cells into secondary lymphoid node formation, as observed in allergic rhinitis, inflammatory bowel disease and other inflammatory disorders. The purpose of this study was to investigate the expression and significance of CCL19 in CRS. Samples of uncinate process mucosa or nasal polyps were taken from patients with CRS (without or with nasal polyps) and normal controls during surgery. Hematoxylin and eosin, periodic acid Schiff and Masson trichrome staining were used for analysis of the nasal polyps. Western blot and immunofluorescence were used to detect CCL19 expression in the nasal polyps and normal nasal mucosa tissues. Spearman correlation analysis was used to analyze the association between CCL19 and blood eosinophil counts. The results showed that CCL19 protein levels in CRS (with or without nasal polyps) were significantly upregulated compared with those in controls. CCL19 expression in eosinophilic CRS was significantly higher than in non-eosinophilic CRS. CCL19 expression in fibroinflammatory and edematous type CRS with nasal polyps was higher than in controls; the upregulation was greater in the edematous type. Immunofluorescence assays showed that CCL19 was mainly expressed by CD68+ macrophages. Spearman correlation analysis demonstrated a positive correlation between CCL19 and blood eosinophils. The upregulation of CCL19 in CRS may play a protective role by limiting eosinophil infiltration and the extent of edema to exert anti-inflammatory and immunomodulatory effects.
- Published
- 2015
33. Characteristic expression and significance of CCL19 in different tissue types in chronic rhinosinusitis
- Author
-
ZOU, YOU, primary, WANG, YAN, additional, WANG, SHUI-BIN, additional, KONG, YONG-GANG, additional, XU, YU, additional, TAO, ZE-ZHANG, additional, and CHEN, SHI-MING, additional
- Published
- 2015
- Full Text
- View/download PDF
34. Crystal structure of bis[1-(4-bromobenzyl)pyridinium] bis(1,2-dicyanoethene-1,2-dithiolato-κ2 S,S′)nickelate(II)
- Author
-
Dong Zeng, Zheng-Fang Tian, and Shui-Bin Yang
- Subjects
crystal structure ,Salt (chemistry) ,Crystal structure ,Dihedral angle ,Medicinal chemistry ,Ion ,square-planar bis-1,2-dithiolate complex ,chemistry.chemical_compound ,maleonitriledithiolate dianion ,General Materials Science ,maleonitriledithiolate dianion ,Benzene ,chemistry.chemical_classification ,square-planar bis-1,2-dithiolate complex ,1-(4-bromobenzyl)pyridinium cation ,Crystallography ,Hydrogen bond ,General Chemistry ,Condensed Matter Physics ,hydrogen bonding ,Data Reports ,1-(4-bromobenzyl)pyridinium cation ,chemistry ,QD901-999 ,Thiol ,Pyridinium ,Ni2+ ion - Abstract
The asymmetric unit of the title salt, (C12H11BrN)2[Ni(C4N2S2)2], consists of one 1-(4-bromobenzyl)pyridinium cation and one half of a complex [Ni(mnt)2]2−(mnt2−is the maleonitriledithiolate dianion). The Ni2+ion is located on an inversion centre and is coordinated by four S atoms from two mnt2−ligands, exhibiting a square-planar coordination environment. In the cation, the planes of the pyridinium and benzene rings make a dihedral angle of 69.86 (19)°. The cations and anions are alternately arranged in layers parallel to (001) and are held together by non-classical C—H...N hydrogen bonds.
- Published
- 2014
35. A digital phase shift method for phase compensation of electronic transformer.
- Author
-
Wei, Wei, Cheng, Han-miao, Li, Fan, Tang, Deng-ping, and Xia, Shui-bin
- Subjects
PHASE shifters ,ELECTRIC transformers ,SIGNAL processing ,LEAST squares ,PERFORMANCE evaluation - Abstract
When sampling analog signal, the electronic transformer generally produces a fixed phase error that will compromise the measurement accuracy and require a phase shift method for correction. In this paper, we propose a digital phase shift method based on least squares fitting algorithm and derive the recursion formula of digital phase shift. The simulation has also been done to analysis its performance. The result shows that the method has high phase shift resolution and precision. By applying the method to an electronic transformer based on Rogowski coil, we have experimentally verified the feasibility and validity of the method. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
36. Intranasal Administration of Lentiviral miR-135a Regulates Mast Cell and Allergen-Induced Inflammation by Targeting GATA-3
- Author
-
Deng, Yu-Qin, primary, Yang, Ya-Qi, additional, Wang, Shui-Bin, additional, Li, Fen, additional, Liu, Meng-Zhi, additional, Hua, Qing-Quan, additional, and Tao, Ze-Zhang, additional
- Published
- 2015
- Full Text
- View/download PDF
37. microRNA-299-3p inhibits laryngeal cancer cell growth by targeting human telomerase reverse transcriptase mRNA
- Author
-
LI, MAN, primary, CHEN, SHI-MING, additional, CHEN, CHEN, additional, ZHANG, ZI-XIONG, additional, DAI, MENG-YUAN, additional, ZHANG, LEI-BO, additional, WANG, SHUI-BIN, additional, DAI, QIONG, additional, and TAO, ZE-ZHANG, additional
- Published
- 2015
- Full Text
- View/download PDF
38. Crystal structure of bis[1-(4-bromobenzyl)pyridinium] bis(1,2-dicyanoethene-1,2-dithiolato-κ2S,S′)nickelate(II)
- Author
-
Zeng, Dong, primary, Yang, Shui-Bin, additional, and Tian, Zheng-Fang, additional
- Published
- 2014
- Full Text
- View/download PDF
39. Characteristic expression and significance of CCL19 in different tissue types in chronic rhinosinusitis.
- Author
-
YOU ZOU, YAN WANG, SHUI-BIN WANG, YONG-GANG KONG, YU XU, ZE-ZHANG TAO, and SHI-MING CHEN
- Subjects
SINUSITIS ,CHEMOKINES ,T cells ,ALLERGIC rhinitis ,INFLAMMATORY bowel diseases ,MUCOUS membranes ,NASAL polyps ,EOSIN - Abstract
Chronic rhinosinusitis (CRS) is a heterogeneous disease, with varying immunological and histopathological features. The CC chemokine ligand 19 (CCL19) can stimulate T cells and antigen-presenting cells into secondary lymphoid node formation, as observed in allergic rhinitis, inflammatory bowel disease and other inflammatory disorders. The purpose of this study was to investigate the expression and significance of CCL19 in CRS. Samples of uncinate process mucosa or nasal polyps were taken from patients with CRS (without or with nasal polyps) and normal controls during surgery. Hematoxylin and eosin, periodic acid Schiff and Masson trichrome staining were used for analysis of the nasal polyps. Western blot and immunofluorescence were used to detect CCL19 expression in the nasal polyps and normal nasal mucosa tissues. Spearman correlation analysis was used to analyze the association between CCL19 and blood eosinophil counts. The results showed that CCL19 protein levels in CRS (with or without nasal polyps) were significantly upregulated compared with those in controls. CCL19 expression in eosinophilic CRS was significantly higher than in non-eosinophilic CRS. CCL19 expression in fibroinflammatory and edematous type CRS with nasal polyps was higher than in controls; the upregulation was greater in the edematous type. Immunofluorescence assays showed that CCL19 was mainly expressed by CD68
+ macrophages. Spearman correlation analysis demonstrated a positive correlation between CCL19 and blood eosinophils. The upregulation of CCL19 in CRS may play a protective role by limiting eosinophil infiltration and the extent of edema to exert anti-inflammatory and immunomodulatory effects. [ABSTRACT FROM AUTHOR]- Published
- 2016
- Full Text
- View/download PDF
40. microRNA-299-3p inhibits laryngeal cancer cell growth by targeting human telomerase reverse transcriptase mRNA.
- Author
-
MAN LI, SHI-MING CHEN, CHEN CHEN, ZI-XIONG ZHANG, MENG-YUAN DAI, LEI-BO ZHANG, SHUI-BIN WANG, QIONG DAI, and ZE-ZHANG TAO
- Subjects
MICRORNA ,GENE expression ,LARYNGEAL cancer ,TELOMERASE reverse transcriptase ,OSTEOSARCOMA - Abstract
Aberrant microRNA (miRNA) expression has been linked to cancer development. In this study, we aimed to investigate whether the anti-cancer effect of miRNA-299-3p on laryngeal cancer Hep-2 cells is mediated through targeting human telomerase reverse transcriptase (hTERT). The expression of miR-299-3p in laryngeal cancer Hep-2 cells and human osteosarcoma U2OS cells was quantified by stem-loop-mediated reverse transcription quantitative polymerase chain reaction. miR-299-3p mimic was transfected into Hep-2 cells to induce overexpression of miR-299-3p. A CCK-8 assay was performed to identify the effects of miR-299-3p overexpression on the proliferation of Hep-2 cells. Western blot analysis was carried out to determine the expression of hTERT protein. A significant decrease was noted in the expression of miR-299-3p in Hep-2 cells compared with that of U2OS cells (P<0.05). Overexpression of miR-299-3p resulted in a notable inhibition of cellular proliferation (P<0.05), as well as downregulation of hTERT mRNA and protein in Hep-2 cells (P>0.05). The expression of miR-299-3p is downregulated in human laryngeal cancer Hep-2 cells. Overexpression of miR-299-3p inhibits Hep-2 cell growth by targeting the 3'-untranslated region of hTERT mRNA. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
41. [Treatmen of distal femoral fracture of Müller type A with homeopathic bidirectional-traction reduction device unite with internal fixation].
- Author
-
Cui Y, Lei J, Wang GQ, Yang J, and Liang SB
- Subjects
- Male, Female, Humans, Adult, Middle Aged, Traction, Treatment Outcome, Fracture Fixation, Internal methods, Bone Plates, Femoral Fractures surgery, Femoral Fractures, Distal
- Abstract
Objective: To investigate the effect of treatment of Müller A fracture of distal femur with small incision internal fixation assisted by homeopathic bidirectional-traction reduction device., Methods: From January 2018 to December 2019, 22 patients (14 males and 8 females) with Müller type A distal femoral fractures were treated with homeopathic bidirectional-traction assisted reduction and minimally invasive small incision locking plate internal fixation;The age ranged from 29 to 58 years old with an average of (41.23±7.03) years. The time from injury to operation was 1 to 7 days with an average of (3.41±1.71) days. According to Müller classification, there were 4 cases of type A1, 10 cases of type A2, and 8 cases of type A3. The postoperative knee joint function was evaluated by Schatzker Lambert fracture criterion of distal femur., Results: All the incisions healed in one stage without infection, osteomyelitis and other complications. All the fractures healed without malunion and nonunion. All of 22 patients were followed up for 12 to 18 months with an average of (14.50±2.02) months. The healing time was 3 to 6 months with an average of (4.64±1.14) months. According to Schatzker Lambert criteria for distal femoral fracture, 12 cases were excellent, 6 good, and 4 medium., Conclusion: It is an ideal method to treat Müller type A fracture of distal femur with homeopathic bidirectional-traction assisted reduction device and minimally invasive small incision locking plate internal fixation.
- Published
- 2023
- Full Text
- View/download PDF
42. Characteristic expression and significance of CCL19 in different tissue types in chronic rhinosinusitis.
- Author
-
Zou Y, Wang Y, Wang SB, Kong YG, Xu YU, Tao ZZ, and Chen SM
- Abstract
Chronic rhinosinusitis (CRS) is a heterogeneous disease, with varying immunological and histopathological features. The CC chemokine ligand 19 (CCL19) can stimulate T cells and antigen-presenting cells into secondary lymphoid node formation, as observed in allergic rhinitis, inflammatory bowel disease and other inflammatory disorders. The purpose of this study was to investigate the expression and significance of CCL19 in CRS. Samples of uncinate process mucosa or nasal polyps were taken from patients with CRS (without or with nasal polyps) and normal controls during surgery. Hematoxylin and eosin, periodic acid Schiff and Masson trichrome staining were used for analysis of the nasal polyps. Western blot and immunofluorescence were used to detect CCL19 expression in the nasal polyps and normal nasal mucosa tissues. Spearman correlation analysis was used to analyze the association between CCL19 and blood eosinophil counts. The results showed that CCL19 protein levels in CRS (with or without nasal polyps) were significantly upregulated compared with those in controls. CCL19 expression in eosinophilic CRS was significantly higher than in non-eosinophilic CRS. CCL19 expression in fibroinflammatory and edematous type CRS with nasal polyps was higher than in controls; the upregulation was greater in the edematous type. Immunofluorescence assays showed that CCL19 was mainly expressed by CD68
+ macrophages. Spearman correlation analysis demonstrated a positive correlation between CCL19 and blood eosinophils. The upregulation of CCL19 in CRS may play a protective role by limiting eosinophil infiltration and the extent of edema to exert anti-inflammatory and immunomodulatory effects.- Published
- 2016
- Full Text
- View/download PDF
43. Crystal structure of bis-[1-(4-bromo-benz-yl)pyridinium] bis-(1,2-di-cyano-ethene-1,2-di-thiol-ato-κ(2) S,S')nickelate(II).
- Author
-
Zeng D, Yang SB, and Tian ZF
- Abstract
The asymmetric unit of the title salt, (C12H11BrN)2[Ni(C4N2S2)2], consists of one 1-(4-bromo-benz-yl)pyridinium cation and one half of a complex [Ni(mnt)2](2-) (mnt(2-) is the maleo-nitrile-dithiol-ate dianion). The Ni(2+) ion is located on an inversion centre and is coordinated by four S atoms from two mnt(2-) ligands, exhibiting a square-planar coordination environment. In the cation, the planes of the pyridinium and benzene rings make a dihedral angle of 69.86 (19)°. The cations and anions are alternately arranged in layers parallel to (001) and are held together by non-classical C-H⋯N hydrogen bonds.
- Published
- 2014
- Full Text
- View/download PDF
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