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Your search keyword '"Cao, Xuebin"' showing total 169 results
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169 results on '"Cao, Xuebin"'

2. Molecular and Physiological Effects of 17α-methyltestosterone on Sex Differentiation of Black Rockfish, Sebastes schlegelii

Author

Huang, Haijun, primary, Liu, Yuyan, additional, Wang, Qian, additional, Dong, Caichao, additional, Dong, Le, additional, Zhang, Jingjing, additional, Yang, Yu, additional, Hao, Xiancai, additional, Li, Weijing, additional, Rosa, Ivana F., additional, Doretto, Lucas B., additional, Cao, Xuebin, additional, and Shao, Changwei, additional

Published
2024
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6. Incidence of Major Adverse Cardiovascular and Cerebrovascular Events in Chinese Patients Undergoing Percutaneous Coronary Intervention with Iodixanol: An Observational Postauthorization Study

Author

Wang, Xiaozeng, primary, Ma, Dengfeng, additional, Li, Tianchang, additional, Li, Bao, additional, Su, Xi, additional, Wu, Yanqing, additional, Du, Zhimin, additional, Ji, Zheng, additional, Yang, Ping, additional, Yang, Baisong, additional, Cao, Xuebin, additional, Li, Junxia, additional, Hou, Fengxia, additional, Cheng, Ziping, additional, Xu, Banglong, additional, and Han, Yaling, additional

Published
2023
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13. Optimization of exercise preconditioning duration in protecting from exhausted exercise-induced cardiac injury in rats.

Author

Ping, Zheng, Li, Jinyu, Sun, Yawei, Zhang, Xiaoli, Wang, Ziwen, and Cao, Xuebin

Subjects
SPRAGUE Dawley rats, EXERCISE, SERUM, CONTROL groups, ELECTROCARDIOGRAPHY
Abstract

The effect of different duration of exercise preconditioning (EP) on protecting from exhaustive exercise-induced cardiac injury (EECI) has been optimized in rats. Male Sprague-Dawley rats were divided into six groups: the control group, exhaustive exercise (EE) group, EP 20-min + EE group, EP 40-min + EE group, EP 60-min + EE group and EP 80-min + EE group. The EP groups were subjected to treadmill running at the intensity of 74.0% V̇O2 max. Changes of exercise capacity, cardiac pathology, myocardial enzymology, electrocardiogram (ECG), cardiac function, and mitochondrial respiratory function were compared. Compared to the C group, the EE group has shown significant decrease of exercise capacity, elevation of serum N-terminal pro B-type natriuretic peptide (NT-proBNP) and cardiac troponin-I (cTn-I) levels, cardiac morphology change, ECG disturbance, cardiac dysfunction and reduction of myocardial mitochondrial respiration function. Compared to the EE group, the EP groups have shown significant elevation of exercise capacity, decrease of serum NT-proBNP and cTn-I, improvement of cardiac function and myocardial mitochondrial electron transfer pathway complex I, II and IV activity. The correlation analyses showed protection of EP was proportional to EP duration from 20-min to 60-min. EE caused cardiac injury. EP could protect from EECI by alleviating myocardial damage, improving cardiac function and mitochondrial ETP complex I, II and IV activity. EP protection was positively correlated to EP duration from 20-min to 60-min with EP intensity fixed at 74.0% V̇O2 max. [ABSTRACT FROM AUTHOR]

Published
2022
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20. Validation of the long-term prognostic capability of the SYNTAX score II in patients undergoing biodegradable polymer-based Sirolimus-eluting stents: 2-year outcomes from the PANDA III trial

Author

Song, Ying, primary, Guan, Changdong, additional, Cao, Xuebin, additional, Qin, Lei, additional, Li, Yi, additional, Li, Zhanquan, additional, Nie, Shaoping, additional, Hou, Shuang, additional, Zhang, Min, additional, Gao, Runlin, additional, Yuan, Jinqing, additional, and Xu, Bo, additional

Published
2020
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26. Two‐year safety evaluation of a biodegradable polymer sirolimus‐eluting stent with increased drug elution and polymer absorption kinetics in complex patient and lesion cohort

Author

Jia, Sida, primary, Guan, Changdong, additional, Yuan, Jinqing, additional, Cao, Xuebin, additional, Qin, Lei, additional, Li, Yi, additional, Li, Zhanquan, additional, Nie, Shaoping, additional, Hou, Shuang, additional, Zhang, Min, additional, Brouwer, Marc, additional, Suryapranata, Harry, additional, Xu, Bo, additional, and Gao, Runlin, additional

Published
2019
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27. Acute Efficacy of a Traditional Chinese Medicine for Treatment of Frequent Premature Ventricular Contractions in Patients with Concomitant Sinus Bradycardia: Results from a Double-Blind, Placebo-Controlled, Multicentre, Randomized Clinical Trial

Author

Zhang, Fengxiang, primary, Zou, Jiangang, additional, Yu, Hao, additional, Li, Xiaorong, additional, Kojodjojo, Pipin, additional, Cai, Xin, additional, Zhang, Shu, additional, Huang, Congxin, additional, Hong, Kui, additional, Yu, Bo, additional, Li, Guangping, additional, Luo, Suxin, additional, Zhou, Shenghua, additional, Zheng, Yang, additional, Fan, Jie, additional, Cao, Xuebin, additional, Tao, Guizhou, additional, Sheng, Guotai, additional, Bai, Zhisheng, additional, Jiang, Shan, additional, Liu, Xiaolin, additional, Gu, Weijuan, additional, Chen, Feng, additional, and Cao, Kejiang, additional

Published
2019
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32. Comparison between two biodegradable polymer-based sirolimus-eluting stents with differing drug elution and polymer absorption kinetics: two-year clinical outcomes of the PANDA III trial

Author

Wang, Juan, primary, Guan, Changdong, additional, Qiao, Shubin, additional, Cao, Xuebin, additional, Qin, Lei, additional, Li, Yi, additional, Li, Zhanquan, additional, Li, Xueqi, additional, Yuan, Jiansong, additional, Gao, Runlin, additional, and Xu, Bo, additional

Published
2018
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39. Numerical Simulation of Variable-Geometry Inlet for TRRE Combined Cycle Engine

Author

Wenhui Ling, Man Yanjin, Ma Jun, Yang Hui, Zhu Shoumei, and Cao Xuebin

Subjects
020301 aerospace & aeronautics, geography, geography.geographical_feature_category, Computer simulation, Combined cycle, 02 engineering and technology, Mechanics, Inlet, 01 natural sciences, 010305 fluids & plasmas, law.invention, 0203 mechanical engineering, law, 0103 physical sciences, Variable geometry, Geology
Published
2017

40. Different Intensity Exercise Preconditions Affect Cardiac Function of Exhausted Rats through Regulating TXNIP/TRX/NF-ĸBp65/NLRP3 Inflammatory Pathways.

Author

Li, Yuemin, Xu, Peng, Wang, Yang, Zhang, Junshi, Yang, Mei, Chang, Yumei, Zheng, Ping, Huang, Heling, and Cao, Xuebin

Subjects
REACTIVE oxygen species, ANIMAL experimentation, BIOMARKERS, BLOOD pressure, C-reactive protein, CARDIAC output, CARDIOVASCULAR diseases risk factors, CELLULAR signal transduction, EXERCISE therapy, EXPERIMENTAL design, HEART rate monitoring, INFLAMMATORY mediators, INTERLEUKINS, MYOCARDIUM, PEPTIDES, PHOSPHOCREATINE, PROTEIN kinases, RATS, TUMOR necrosis factors, WESTERN immunoblotting, DNA-binding proteins, OXIDATIVE stress, EXERCISE intensity, CASPASES, SIGNAL peptides, STROKE volume (Cardiac output), VENTRICULAR ejection fraction
Abstract

Objective. To investigate whether exercise preconditioning (EP) improves the rat cardiac dysfunction induced by exhaustive exercise (EE) through regulating NOD-like receptor protein 3 (NLRP3) inflammatory pathways and to confirm which intensity of EP is better. Method. Ninety healthy male Sprague Dawley rats were randomly divided into five groups: a control group (CON), exhaustive exercise group (EE), low-, middle-, and high-intensity exercise precondition and exhaustive exercise group (LEP + EE, MEP + EE, HEP + EE group). We established the experimental model by referring to Bedford's motion load standard to complete the experiment. Then, the pathological changes of the myocardium were observed under a light microscope. Biomarker of myocardial injury in serum and oxidative stress factor in myocardial tissue were evaluated by ELISAs. The cardiac function parameters were detected using a Millar pressure and volume catheter. The levels of thioredoxin-interacting protein (TXNIP), thioredoxin protein (TRX), nuclear transcription factor kappa Bp65 (NF-ĸBp65), NLRP3, and cysteinaspartate specific proteinase 1 (Caspase-1) protein in rats' myocardium were detected by western blotting. Results. 1. The myocardial structures of three EP + EE groups were all improved compared with EE groups. 2. The levels of the creatine phosphating-enzyme MB (CK-MB), reactive oxygen species (ROS), interleukin-6 (IL-6), C-reactive protein (CRP), and tumor necrosis factor alpha (TNF-α) in three EP + EE groups were all increased compared with CON but decreased compared with the EE group (P < 0.05). 3. Compared with the CON group, slope of end-systolic pressure volume relationship (ESPVR), ejection fraction (EF), and peak rate of the increase in pressure (dP/dtmax) all dropped to the lowest level in the EE group (P < 0.05), while the values of cardiac output (CO), stroke volume (SV), end-systolic volume (Ves), end-diastolic volume (Ved), and relaxation time constant (Tau) increased in the EE group (P < 0.05). 4. Compared with the CON group, the expression levels of TXNIP, NF-ĸBp65, NLRP3, and Caspase-1 all increased obviously in the other groups (P < 0.05); meanwhile, they were all decreased in three EP + EE groups compared with the EE group (P < 0.05). 5. NLRP3 was positively correlated with heart rate, IL-6, and ROS, but negatively correlated with EF (P < 0.01). Conclusion. EP protects the heart from EE-induced injury through downregulating TXNIP/TRX/NF-ĸBp65/NLRP3 inflammatory signaling pathways. Moderate intensity EP has the best protective effect. [ABSTRACT FROM AUTHOR]

Published
2020
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