Author: "Buyne OR" / Publication Year Range: Last 10 years - Searchworks@Jio Institute Digital Library Search Results

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114 results on '"Buyne OR"'

1. Self-assessment, and not continuous training, improves basic open suturing skills

Author: Vera Hillemans, Otmar Buyne, Ivo de Blaauw, Sanne M.B.I. Botden, Bas H. Verhoeven, and Maja Joosten
Subjects: Basic open suturing tasks, tracking, continuous training, self-assessment, reflection before practice, Special aspects of education, LC8-6691, Medicine (General), R5-920
Abstract: Background To develop and maintain suturing skills, clinical exposure is important. When clinical exposure cannot be guaranteed, an adequate training schedule for suturing skills is required. This study evaluates the effect of continuous training, ‘reflection before practice’ and self-assessment on basic open suturing skills.Methods Medical students performed four basic suturing tasks on a simulation set up before (‘pre-test’) and after their surgical rotation (‘after-test’). Participants were divided in three groups; the ‘clinical exposure group’ (n = 44) had clinical exposure during their rotation only, the ‘continuous training group’ (n = 16) completed a suturing interval training during their rotation and the ‘self-assessment group’ (n = 16) also completed a suturing interval training, but with the use of reflection before practice and self-assessment. Parameters measured by a tracking system during the suturing tasks and a calculated ‘composite score’ were compared between groups and test-moments.Results A significantly better composite score was found at the after-test compared to the pre-test for all groups for all basic suturing tasks (0.001 ≤ p ≤ 0.049). The self-assessment group scored better at the pre-test than the other two groups for all tasks, except for ‘knot tying by hand’ (0.004 ≤ p ≤ 0.063). However, this group did not score better at the after-test for all tasks, compared to the other two groups. This resulted in a smaller delta of time (‘transcutaneous suture’, p = 0.013), distance (‘Donati suture’ and ‘intracutaneous suture’, 0.005 ≤ p ≤ 0.009) or composite score (all tasks, except for knot tying by hand, 0.007 ≤ p ≤ 0.061) in the self-assessment group.Conclusion Reflection before practice and self-assessment during continuous training of basic open suturing tasks, may improve surgical skills at the start of the learning curve.
Published: 2024
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2. Concurrent validity of objective assessment by finger tracking for open surgical suturing training

Author: Hillemans, Vera, Verhoeven, Daan J., Buyne, Otmar, de Blaauw, Ivo, Botden, Sanne M.B.I., and Verhoeven, Bas H.
Published: 2024
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3. Unraveling factors associated with textbook outcome after cholecystectomy in patients with uncomplicated cholecystolithiasis: A posthoc analysis of individual data of 1,124 patients

Author: Buyne, Otmar, Donkervoort, Sandra C., Heisterkamp, Joos, Hof, Klaas in ‘t, Diepenhorst, Gwen, van der Bilt, Jarmila, Jansen, Jan, Nieuwenhuijs, Vincent B., Steenvoorde, Pascal, Boerma, Djamila, Heikens, Joost T., Schreinemakers, Jennifer M.J., Wiering, Bastiaan, Stockmann, Hein B.A.C., van Duijvendijk, Peter, Boermeester, Marja A., Comes, Daan J., Thunnissen, Floris M., Latenstein, Carmen S.S., Stommel, Martijn W.J., van Laarhoven, Cornelis J.H.M., Drenth, Joost P.H., Atsma, Femke, Lantinga, Marten A., and de Reuver, Philip R.
Published: 2024
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4. Objective assessment for open surgical suturing training by finger tracking can discriminate novices from experts

Author: Vera Hillemans, Xander van de Mortel, Otmar Buyne, Bas H. Verhoeven, and Sanne M.B.I. Botden
Subjects: Tracking, surgical simulation, basic suturing tasks, open surgery, construct validity, Special aspects of education, LC8-6691, Medicine (General), R5-920
Abstract: ABSTRACTIt is difficult, time consuming and expensive to assess manual skills in open surgery. The aim of this study is to investigate the construct validity of a low-cost, easily accessible tracking technique for basic open suturing tasks. Medical master students, surgical residents, and surgeons at the Radboud University Medical Center were recruited between September 2020 until September 2021. The participants were divided, according to experience, in a novice group (≤10 sutures performed) and an expert group (>50 sutures performed). For objective tracking, a tablet with SurgTrac software was used, which tracked a blue and a red tag placed on respectively their left and right index finger. The participants executed four basic tasks on a suturing model: 1) knot tying by hand, 2) transcutaneous suturing with an instrument knot, 3) ‘Donati’ (vertical mattress suture) with an instrument knot and 4) continuous intracutaneous suturing without a knot. In total 76 participants were included: 57 novices and 19 experts. All four tasks showed significant differences between the novice group and expert group for the parameters time (p
Published: 2023
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5. Persistent and new-onset symptoms after cholecystectomy in patients with uncomplicated symptomatic cholecystolithiasis: A post hoc analysis of 2 prospective clinical trials

Author: Buyne, Otmar, Donkervoort, Sandra C., Heisterkamp, Joos, ’t Hof, Klaas in, Jansen, Jan, Nieuwenhuijs, Vincent B., Schaap, Henk M., Steenvoorde, Pascal, Boerma, Djamila, Hazebroek, Eric J., Hirsch, David, Heikens, Joost T., Konsten, Joop, Polat, Fatih, van der Bilt, Jarmila D.W., Schreinemakers, Jennifer M.J., Wiering, Bastiaan, Stockmann, Hein B.A.C., Boermeester, Marja, Thunnissen, Floris M., Baars, Cléo, Arts, Rianne, Latenstein, Carmen S.S., Drenth, Joost P.H., van Laarhoven, Cornelis J.H.M., Lantinga, Marten A., and de Reuver, Philip R.
Published: 2023
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6. A mixed-methods study to define Textbook Outcome for the treatment of patients with uncomplicated symptomatic gallstone disease with hospital variation analyses in Dutch trial data

Author: Eijsbouts, Quirijn A.J., Heisterkamp, Joos, Boerma, Djamila, Jennifer, M.J., van Duivendijk, Peter, Wiering, Bastiaan, Boermeester, Marja A., Diepenhorst, Gwen, van der Bilt, Jarmila, Buyne, Otmar, Venneman, Niels G., Keszthelyi, Daniel, Ahmed, Ifran, Hugh, Thomas J., Wigmore, Stephen J., Strasberg, Steven M., Harrison, Ewen M., Lammert, Frank, Gurusamy, Kurinchi, Moris, Dimitros, Soreide, Kjetil, Pappas, Theodore N., Kapoor, Vinay K., Speelman, Antonia, van den Brink, Chris, Thunnissen, Floris M., Comes, Daan J., Latenstein, Carmen S.S., Stommel, Martijn W.J., van Laarhoven, Cornelis J.H.M., Drenth, Joost P.H., Lantinga, Marten A., Atsma, Femke, and de Reuver, Philip R.
Published: 2023
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7. Self-assessment, and not continuous training, improves basic open suturing skills.

Author: Hillemans, Vera, Buyne, Otmar, de Blaauw, Ivo, Botden, Sanne M.B.I., Verhoeven, Bas H., and Joosten, Maja
Subjects: LEARNING curve, MEDICAL students, INTERVAL training, CONTINUOUS groups, SUTURING
Abstract: Background: To develop and maintain suturing skills, clinical exposure is important. When clinical exposure cannot be guaranteed, an adequate training schedule for suturing skills is required. This study evaluates the effect of continuous training, 'reflection before practice' and self-assessment on basic open suturing skills. Methods: Medical students performed four basic suturing tasks on a simulation set up before ('pre-test') and after their surgical rotation ('after-test'). Participants were divided in three groups; the 'clinical exposure group' (n = 44) had clinical exposure during their rotation only, the 'continuous training group' (n = 16) completed a suturing interval training during their rotation and the 'self-assessment group' (n = 16) also completed a suturing interval training, but with the use of reflection before practice and self-assessment. Parameters measured by a tracking system during the suturing tasks and a calculated 'composite score' were compared between groups and test-moments. Results: A significantly better composite score was found at the after-test compared to the pre-test for all groups for all basic suturing tasks (0.001 ≤ p ≤ 0.049). The self-assessment group scored better at the pre-test than the other two groups for all tasks, except for 'knot tying by hand' (0.004 ≤ p ≤ 0.063). However, this group did not score better at the after-test for all tasks, compared to the other two groups. This resulted in a smaller delta of time ('transcutaneous suture', p = 0.013), distance ('Donati suture' and 'intracutaneous suture', 0.005 ≤ p ≤ 0.009) or composite score (all tasks, except for knot tying by hand, 0.007 ≤ p ≤ 0.061) in the self-assessment group. Conclusion: Reflection before practice and self-assessment during continuous training of basic open suturing tasks, may improve surgical skills at the start of the learning curve. [ABSTRACT FROM AUTHOR]
Published: 2024
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8. Restrictive Strategy vs Usual Care for Cholecystectomy in Patients With Abdominal Pain and Gallstones: 5-Year Follow-Up of the SECURE Randomized Clinical Trial.

Author: Comes, Daan J., Wennmacker, Sarah Z., Latenstein, Carmen S. S., van der Bilt, Jarmila, Buyne, Otmar, Donkervoort, Sandra C., Heisterkamp, Joos, in't Hof, Klaas, Jansen, Jan, Nieuwenhuijs, Vincent B., Steenvoorde, Pascal, Stockmann, Hein B. A. C., Boerma, Djamila, Drenth, Joost P. H., van Laarhoven, Cornelis J. H. M., Boermeester, Marja A., Dijkgraaf, Marcel G. W., and de Reuver, Philip R.
Published: 2024
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9. Acute buik

Author: Buyne, O. R., van Geloven, A. A. W., Heineman, E., editor, Heineman, D.J., editor, Lange jr., J.F.M., editor, Blankensteijn, J.D., editor, Boermeester, M.A., editor, Borel Rinkes, I.H.M., editor, Klaase, J.M., editor, Schipper, I.B., editor, Schreurs, W.H., editor, and Wijnen, R.M.H., editor
Published: 2021
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10. Unraveling factors associated with textbook outcome after cholecystectomy in patients with uncomplicated cholecystolithiasis: A posthoc analysis of individual data of 1,124 patients

Author: Comes, Daan J., primary, Thunnissen, Floris M., additional, Latenstein, Carmen S.S., additional, Stommel, Martijn W.J., additional, van Laarhoven, Cornelis J.H.M., additional, Drenth, Joost P.H., additional, Atsma, Femke, additional, Lantinga, Marten A., additional, de Reuver, Philip R., additional, Buyne, Otmar, additional, Donkervoort, Sandra C., additional, Heisterkamp, Joos, additional, Hof, Klaas in ‘t, additional, Diepenhorst, Gwen, additional, van der Bilt, Jarmila, additional, Jansen, Jan, additional, Nieuwenhuijs, Vincent B., additional, Steenvoorde, Pascal, additional, Boerma, Djamila, additional, Heikens, Joost T., additional, Schreinemakers, Jennifer M.J., additional, Wiering, Bastiaan, additional, Stockmann, Hein B.A.C., additional, van Duijvendijk, Peter, additional, and Boermeester, Marja A., additional
Published: 2024
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11. Imaging based flowchart for gallbladder polyp evaluation

Author: Schreinemakers, Jennifer M.J., Heisterkamp, Joos, Hansson, Bibi, Buyne, Otmar, Nieuwenhuijs, Vincent B., Spillenaar Bilgen, Ernst Jan, Bosscha, Koop, Wennmacker, Sarah Z., de Savornin Lohman, Elise A.J., de Reuver, Philip R., Drenth, Joost P.H., van der Post, Rachel S., Nagtegaal, Iris D., Hermans, John J., and van Laarhoven, Cornelis J.H.M.
Published: 2021
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12. Pelvic Floor Rehabilitation After Rectal Cancer Surgery: A Multicenter Randomized Clinical Trial (FORCE Trial)

Author: van der Heijden, J. A. G., Kalkdijk-Dijkstra, A. J., Pierie, J. P. E. N., van Westreenen, H. L., Broens, P. M. A., Klarenbeek, B. R., de Wilt, JHW, Stommel, MWJ, Bremers, AJA, Rosman, C, de Reuver, PR, Bouwense, SAW, van der Kolk, BM, Garms, LM, Meerten-van den Belt, K, Olde Hartman-Hofste, MRM, Peters, JWM, Olsder, L, Huizing, I, Trzpis, M, Furnee, EJB, Havenga, K, Hemmer, PHJ, van Etten, B, Koop, A, van der Heide, L, Kamphuis, D, Koopal, SA, Hoff, C, Eker, H, Junte, HHM, Schoenaker, IJH, Quaedackers, S, Bos, MJ, Gardien, H, van Sprundel, TC, de Vries, PD, Ashruf, JF, Geurts, L, Nielen, I, Pfeil, J, van Ark, M, Polle, SW, Hansson, B, Polat, F, de Vries, H, ten Berge-Groen, E, Talsma, AK, Bosker, R, Veurink, E, Papa, M, Maaskant-Braat, AJG, van den Broek, FJC, Leclercq, WKG, Slooter, GD, Caers, F, Boeijen, M, van den Broek, R, van Schaik, K, Wasowicz-Kemps, DK, Langenhoff, BS, van den Bogaard, MJ, van der Sluis, J, Arisz, D, Bruinsma, S, Hess, DA, Mulder, EJ, Wiering, B, Kok, S, Woltering, J, Raap-van Sleuwen, B, Schoonderwoerd, L, Hendriks, D, van den Elzen, N, van de Laak, I, Valk, M, van der Meij, W, van Wely, BJ, van Hoogstraten, MJ, van der Sluis, M, Paulusma, I, Mollers, MJW, Looijen, R, van der Mijle, HCJ, Pereboom, ITA, Tijink-Callenbach, PMC, Schasfoort, RA, van der Hagen, SJ, van de Meer, W, Lubberink, M, van Haskera, M, Wit, F, Jeeninga, M, ten Hoeve, R, Slootmans, FCW, Inberg, B, de Nes, L, Toonen, D, Wilmsen, MA, Buyne, O, Ferenschild, F, de Vries, M., Adamse, C, Hettema-Beets, BL, Goudswaard, MK, van der Velde, M, Elving, DW, Arends-Smit, RE, Buiter, JR, van der itte-van Aerle, I, Jansma, K, Kooistra, L, Lohof-Venema, S, Kruijer, MR, Dijkstra, G, van der erf-Elling, MA, Kats-de Boer, V, Rinsema, AM, Haarlemmer-Lutjeboer, M, van der Vegt, A, Berends-Pors, SMH, Ponstein, AJ, Klaassen, G, Nieuwint, AM, Veninga-Jansen, M, Dries-Jansen, V, Arends, FJ, Stellingwerf-Goinga, NE, Overmars, NG, van Asma, H, Beverdam, K, Ploumen, MJAC, Tijhuis, M, Visser Duiven, AH, Former, M, Smans-Kaal, MAL, Vorsterman van Oijen-Linthorst, CMJ, Hovels-Kamp, NN, Vorsteveld, LR, Vermeulen, N, Alkemade-van Veghel, A, Steentjes, LJ, Cornelisse-Theunissen, HGM, Strijbosch, J, Sniekers, S, Oerlemans-van Oijen, JMA, Hoefnagels, HMJ, Sniekers, CJDA, Biemans, S, Bomert-Wendt, Y, van Gaal, HGM, Smulders, AHCW, Adams, W, Kappen, JM, Vermeltfoort-Jansen, AM, Zegger, MGC, Vrielink, C, Slotman, HM, Claessens, NJH, Manders-de Groot, AWM, van Beuzekom-van der Vorst, CTPG, Swinkels-Nijssen, MWC, van Oeveren, P, van Leeuwen-Nellestijn, JPF, Bleijenberg, M, Valenteyn-Hidden, JJF, van Rutten-de Groot, MG, van den van der Heijden, M, Nieuwenhuizen, Boorsma, PG, Broodman, N, Elling, ME, Bokkers-Engelen, E, Hilhorst-Droppers, GH, Mein, HJC, and Gielen, M
Published: 2022
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13. Restrictive strategy versus usual care for cholecystectomy in patients with gallstones and abdominal pain (SECURE): a multicentre, randomised, parallel-arm, non-inferiority trial

Author: van Dijk, Aafke H, Wennmacker, Sarah Z, de Reuver, Philip R, Latenstein, Carmen S S, Buyne, Otmar, Donkervoort, Sandra C, Eijsbouts, Quirijn A J, Heisterkamp, Joos, Hof, Klaas in 't, Janssen, Jan, Nieuwenhuijs, Vincent B, Schaap, Henk M, Steenvoorde, Pascal, Stockmann, Hein B A C, Boerma, Djamila, Westert, Gert P, Drenth, Joost P H, Dijkgraaf, Marcel G W, Boermeester, Marja A, and van Laarhoven, Cornelius J H M
Published: 2019
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14. Corrigendum to ‘A mixed-methods study to define Textbook Outcome for the treatment of patients with uncomplicated symptomatic gallstone disease with hospital variation analyses in Dutch trial data’ [Volume 25, Issue 9, September 2023, Pages 1000–1010]

Author: Thunnissen, Floris M., primary, Comes, Daan J., additional, Latenstein, Carmen S.S., additional, Stommel, Martijn W.J., additional, van Laarhoven, Cornelis J.H.M., additional, Drenth, Joost P.H., additional, Lantinga, Marten A., additional, Atsma, Femke, additional, de Reuver, Philip R., additional, Eijsbouts, Quirijn A.J., additional, Heisterkamp, Joos, additional, Boerma, Djamila, additional, Jennifer, M.J., additional, van Duivendijk, Peter, additional, Wiering, Bastiaan, additional, Boermeester, Marja A., additional, Diepenhorst, Gwen, additional, van der Bilt, Jarmila, additional, Buyne, Otmar, additional, Venneman, Niels G., additional, Keszthelyi, Daniel, additional, Ahmed, Ifran, additional, Hugh, Thomas J., additional, Wigmore, Stephen J., additional, Strasberg, Steven M., additional, Harrison, Ewen M., additional, Lammert, Frank, additional, Gurusamy, Kurinchi, additional, Moris, Dimitros, additional, Soreide, Kjetil, additional, Pappas, Theodore N., additional, Kapoor, Vinay K., additional, Speelman, Antonia, additional, and van den Brink, Chris, additional
Published: 2023
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15. Abdominal wall defects: pathogenesis, prevention and repair

Author: Knaapen, Loes, Slater, Nicholas J., Buyne, Otmar R., and van Goor, Harry
Published: 2018
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16. Persistent and new-onset symptoms after cholecystectomy in patients with uncomplicated symptomatic cholecystolithiasis: A post hoc analysis of 2 prospective clinical trials

Author: Thunnissen, Floris M., primary, Baars, Cléo, additional, Arts, Rianne, additional, Latenstein, Carmen S.S., additional, Drenth, Joost P.H., additional, van Laarhoven, Cornelis J.H.M., additional, Lantinga, Marten A., additional, de Reuver, Philip R., additional, Buyne, Otmar, additional, Donkervoort, Sandra C., additional, Heisterkamp, Joos, additional, ’t Hof, Klaas in, additional, Jansen, Jan, additional, Nieuwenhuijs, Vincent B., additional, Schaap, Henk M., additional, Steenvoorde, Pascal, additional, Boerma, Djamila, additional, Hazebroek, Eric J., additional, Hirsch, David, additional, Heikens, Joost T., additional, Konsten, Joop, additional, Polat, Fatih, additional, van der Bilt, Jarmila D.W., additional, Schreinemakers, Jennifer M.J., additional, Wiering, Bastiaan, additional, Stockmann, Hein B.A.C., additional, and Boermeester, Marja, additional
Published: 2023
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17. A mixed-methods study to define Textbook Outcome for the treatment of patients with uncomplicated symptomatic gallstone disease with hospital variation analyses in Dutch trial data

Author: Thunnissen, Floris M., primary, Comes, Daan J., additional, Latenstein, Carmen S.S., additional, Stommel, Martijn W.J., additional, van Laarhoven, Cornelis J.H.M., additional, Drenth, Joost P.H., additional, Lantinga, Marten A., additional, Atsma, Femke, additional, de Reuver, Philip R., additional, Eijsbouts, Quirijn A.J., additional, Heisterkamp, Joos, additional, Boerma, Djamila, additional, Jennifer, M.J., additional, van Duivendijk, Peter, additional, Wiering, Bastiaan, additional, Boermeester, Marja A., additional, Diepenhorst, Gwen, additional, van der Bilt, Jarmila, additional, Buyne, Otmar, additional, Venneman, Niels G., additional, Keszthelyi, Daniel, additional, Ahmed, Ifran, additional, Hugh, Thomas J., additional, Wigmore, Stephen J., additional, Strasberg, Steven M., additional, Harrison, Ewen M., additional, Lammert, Frank, additional, Gurusamy, Kurinchi, additional, Moris, Dimitros, additional, Soreide, Kjetil, additional, Pappas, Theodore N., additional, Kapoor, Vinay K., additional, Speelman, Antonia, additional, and van den Brink, Chris, additional
Published: 2023
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18. Objective assessment for open surgical suturing training by finger tracking can discriminate novices from experts.

Author: Hillemans, V., Mortel, X. van de, Buyne, O.R., Verhoeven, B.H., Botden, S.M.B.I., Hillemans, V., Mortel, X. van de, Buyne, O.R., Verhoeven, B.H., and Botden, S.M.B.I.
Abstract: 01 december 2023, Item does not contain fulltext, It is difficult, time consuming and expensive to assess manual skills in open surgery. The aim of this study is to investigate the construct validity of a low-cost, easily accessible tracking technique for basic open suturing tasks. Medical master students, surgical residents, and surgeons at the Radboud University Medical Center were recruited between September 2020 until September 2021. The participants were divided, according to experience, in a novice group (≤10 sutures performed) and an expert group (>50 sutures performed). For objective tracking, a tablet with SurgTrac software was used, which tracked a blue and a red tag placed on respectively their left and right index finger. The participants executed four basic tasks on a suturing model: 1) knot tying by hand, 2) transcutaneous suturing with an instrument knot, 3) 'Donati' (vertical mattress suture) with an instrument knot and 4) continuous intracutaneous suturing without a knot. In total 76 participants were included: 57 novices and 19 experts. All four tasks showed significant differences between the novice group and expert group for the parameters time (p<0.001), distance (p<0.001 for Task 1, 2 and 3 and p=0.034 for Task 4) and smoothness (p<0.001). Additionally, Task 3 showed a significant difference for the parameter handedness (p=0.006) and Task 4 for speed (p=0.033). Tracking index finger movements using SurgTrac software on a tablet while executing basic open suturing skills on a simulator shows excellent construct validity for time, distance and motion smoothness in all four suturing tasks.
Published: 2023

19. Objective assessment for open surgical suturing training by finger tracking can discriminate novices from experts.

Author: Hillemans, Vera, van de Mortel, Xander, Buyne, Otmar, Verhoeven, Bas H., and Botden, Sanne M. B. I.
Subjects: SUTURING, SUTURES, ACADEMIC medical centers, MOTOR ability, FINGERS
Abstract: It is difficult, time consuming and expensive to assess manual skills in open surgery. The aim of this study is to investigate the construct validity of a low-cost, easily accessible tracking technique for basic open suturing tasks. Medical master students, surgical residents, and surgeons at the Radboud University Medical Center were recruited between September 2020 until September 2021. The participants were divided, according to experience, in a novice group (=10 sutures performed) and an expert group (>50 sutures performed). For objective tracking, a tablet with SurgTrac software was used, which tracked a blue and a red tag placed on respectively their left and right index finger. The participants executed four basic tasks on a suturing model: 1) knot tying by hand, 2) transcutaneous suturing with an instrument knot, 3) 'Donati' (vertical mattress suture) with an instrument knot and 4) continuous intracutaneous suturing without a knot. In total 76 participants were included: 57 novices and 19 experts. All four tasks showed significant differences between the novice group and expert group for the parameters time (p<0.001), distance (p<0.001 for Task 1, 2 and 3 and p=0.034 for Task 4) and smoothness (p<0.001). Additionally, Task 3 showed a significant difference for the parameter handedness (p=0.006) and Task 4 for speed (p=0.033). Tracking index finger movements using SurgTrac software on a tablet while executing basic open suturing skills on a simulator shows excellent construct validity for time, distance and motion smoothness in all four suturing tasks. [ABSTRACT FROM AUTHOR]
Published: 2023
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20. Erratum to: Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)

Author: M. Sartelli, D. G. Weber, E. Ruppé, M. Bassetti, B. J. Wright, L. Ansaloni, F. Catena, F. Coccolini, F. M. Abu-Zidan, R. Coimbra, E. E. Moore, F. A. Moore, R. V. Maier, J. J. De Waele, A. W. Kirkpatrick, E. A. Griffiths, C. Eckmann, A. J. Brink, J. E. Mazuski, A. K. May, R. G. Sawyer, D. Mertz, P. Montravers, A. Kumar, J. A. Roberts, J. L. Vincent, R. R. Watkins, W. Lowman, B. Spellberg, I. J. Abbott, A. K. Adesunkanmi, S. Al-Dahir, M. N. Al-Hasan, F. Agresta, A. A. Althani, S. Ansari, R. Ansumana, G. Augustin, M. Bala, Z. J. Balogh, O. Baraket, A. Bhangu, M. A. Beltrán, M. Bernhard, W. L. Biffl, M. A. Boermeester, S. M. Brecher, J. R. Cherry-Bukowiec, O. R. Buyne, M. A. Cainzos, K. A Cairns, A. Camacho-Ortiz, S. J. Chandy, A. Che Jusoh, A. Chichom-Mefire, C. Colijn, F. Corcione, Y. Cui, D. Curcio, S. Delibegovic, Z. Demetrashvili, B. De Simone, S. Dhingra, J. J. Diaz, I. Di Carlo, A. Dillip, S. Di Saverio, M. P. Doyle, G. Dorj, A. Dogjani, H. Dupont, S. R. Eachempati, M. A. Enani, V. N. Egiev, M. M. Elmangory, P. Ferrada, J. R. Fitchett, G. P. Fraga, N. Guessennd, H. Giamarellou, W. Ghnnam, G. Gkiokas, S. R. Goldberg, C. A. Gomes, H. Gomi, M. Guzmán-Blanco, M. Haque, S. Hansen, A. Hecker, W. R. Heizmann, T. Herzog, A. M. Hodonou, S. K. Hong, R. Kafka-Ritsch, L. J. Kaplan, G. Kapoor, A. Karamarkovic, M. G. Kees, J. Kenig, R. Kiguba, P. K. Kim, Y. Kluger, V. Khokha, K. Koike, K. Y. Kok, V. Kong, M. C. Knox, K. Inaba, A. Isik, K. Iskandar, R. R. Ivatury, M. Labbate, F. M. Labricciosa, P. F. Laterre, R. Latifi, J. G. Lee, Y. R. Lee, M. Leone, A. Leppaniemi, Y. Li, S. Y. Liang, T. Loho, M. Maegele, S. Malama, H. E. Marei, I. Martin-Loeches, S. Marwah, A. Massele, M. McFarlane, R. B. Melo, I. Negoi, D. P. Nicolau, C. E. Nord, R. Ofori-Asenso, A. H. Omari, C. A. Ordonez, M. Ouadii, G. A. Pereira Júnior, D. Piazza, G. Pupelis, T. M. Rawson, M. Rems, S. Rizoli, C. Rocha, B. Sakakushev, M. Sanchez-Garcia, N. Sato, H. A. Segovia Lohse, G. Sganga, B. Siribumrungwong, V. G. Shelat, K. Soreide, R. Soto, P. Talving, J. V. Tilsed, J. F. Timsit, G. Trueba, N. T. Trung, J. Ulrych, H. van Goor, A. Vereczkei, R. S. Vohra, I. Wani, W. Uhl, Y. Xiao, K. C. Yuan, S. K. Zachariah, J. R. Zahar, T. L. Zakrison, A. Corcione, R. M. Melotti, C. Viscoli, and P. Viale
Subjects: Surgery, RD1-811, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Published: 2017
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21. Right-Sided Bochdalek Hernia with Cecum Perforation

Author: Tina Natroshvili, Dashti Faraj, Emmy Janssen, Harry van Goor, Melanie Hartman, and Otmar R. Buyne
Subjects: Thorax, medicine.medical_specialty, business.industry, medicine.medical_treatment, Perforation (oil well), Diaphragmatic breathing, medicine.disease, digestive system diseases, Surgery, Bochdalek hernia, stomatognathic diseases, surgical procedures, operative, medicine.anatomical_structure, Epigastrium, medicine, Ascending colon, Abdomen, business, Watchful waiting
Abstract: Background: A Bochdalek hernia is one of the most frequently occurring congenital diaphragmatic hernias, and it occurs in 1 out of 2,500 births. Clinical cases of adults with symptomatic Bochdalek hernias are very rare. We describe a patient with an incarcerated Bochdalek hernia who underwent emergency surgery and presented with a recurrence after three years. Comparable cases in the literature were reviewed. Case Presentation: A 56-year-old woman presented to the emergency department with acute dyspnea and pain in the epigastrium shortly after gastroscopy. A CT scan showed right sided intrathoracic herniation of the ascending colon and signs of perforation of a hollow viscus. During the operation, a suture repair of a cecal perforation as well as of a diagrammatic lesion was performed. The thorax and abdomen were lavaged and drained. The postoperative course was uneventful. After 3 years, the patient presented with colic pain in the upper abdominal quadrants. A small recurrence of the Bochdalek hernia was observed on a computed tomography scan and was managed with watchful waiting. A systematic search of comparable acute cases of Bochdalek hernias was performed. Conclusion: An incarcerated right colon with a perforation in a Bochdalek hernia is extremely rare; only 11 comparable cases of right sided Bochdalek hernia with acute symptoms are described in the literature. Recurrent Bochdalek hernias are even rarer. As a delay in the diagnosis or a missed diagnosis can ultimately lead to death, adequate imaging is warranted when considering a recurrence of a Bochdalek hernia.
Published: 2020
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22. Embodied Resistance: An Interdisciplinary Analysis of Contemporary Protest against black Pete

Author: Buyne, Nicchelle, Slooter, Luuk (Thesis Advisor), Buyne, Nicchelle, and Slooter, Luuk (Thesis Advisor)
Abstract: In 2011, activists Quinsy Gario and Jerry Afriyie challenged the festive nature of the Netherlands' annual St. Nicholas celebration by wearing t-shirts with the slogan "Zwarte Piet is Racism" [Black Pete is Racism] at the national ceremonial arrival in Dordrecht. Their message shocked the audience and resulted in their controversial arrest. Afriyie and Gario's action marked the beginning of a new cycle of social movement against black Pete. This research utilises insights from contentious politics, dramaturgy and social psychology on social movement to analyse anti-black Pete protest participation. Through an examination of the drivers and performance of black Pete opposition, it provides insight into the perceptions of the individuals that instigated a heated societal debate which resulted in significant changes to the celebration of St. Nicholas. It draws on qualitative data derived from interviews with 25 respondents to construct a holistic conceptualisation of individuals' protest experiences. As a result, it presents anti-black-Pete protest as a symbolically meaningful effort to address racism in the Netherlands.
Published: 2022

23. Corrigendum to ‘A mixed-methods study to define Textbook Outcome for the treatment of patients with uncomplicated symptomatic gallstone disease with hospital variation analyses in Dutch trial data’ [Volume 25, Issue 9, September 2023, Pages 1000–1010]

Author: Eijsbouts, Quirijn A.J., Heisterkamp, Joos, Boerma, Djamila, Jennifer, M.J., van Duivendijk, Peter, Wiering, Bastiaan, Boermeester, Marja A., Diepenhorst, Gwen, van der Bilt, Jarmila, Buyne, Otmar, Venneman, Niels G., Keszthelyi, Daniel, Ahmed, Ifran, Hugh, Thomas J., Wigmore, Stephen J., Strasberg, Steven M., Harrison, Ewen M., Lammert, Frank, Gurusamy, Kurinchi, Moris, Dimitros, Soreide, Kjetil, Pappas, Theodore N., Kapoor, Vinay K., Speelman, Antonia, van den Brink, Chris, Thunnissen, Floris M., Comes, Daan J., Latenstein, Carmen S.S., Stommel, Martijn W.J., van Laarhoven, Cornelis J.H.M., Drenth, Joost P.H., Lantinga, Marten A., Atsma, Femke, and de Reuver, Philip R.
Published: 2024
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24. Pre-operative CT scan measurements for predicting complications in patients undergoing complex ventral hernia repair using the component separation technique

Author: Stefan Hummelink, Nicholas J. Slater, Harm Winters, Dietmar J.O. Ulrich, E. van Geffen, O.R. Buyne, H. van Goor, and L. Knaapen
Subjects: Adult, Male, medicine.medical_specialty, Complex ventral hernia, Waist, 030230 surgery, Risk Assessment, BMI, Young Adult, 03 medical and health sciences, All institutes and research themes of the Radboud University Medical Center, 0302 clinical medicine, Fat volume, Risk Factors, medicine, Humans, Surgical Wound Infection, Medical history, In patient, Risk factor, Herniorrhaphy, Aged, Retrospective Studies, business.industry, Ventral hernia repair, Postoperative complication, Middle Aged, Hernia, Ventral, Sagittal plane, Women's cancers Radboud Institute for Health Sciences [Radboudumc 17], 3. Good health, Surgery, Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10], Component separation technique, Reconstructive and regenerative medicine Radboud Institute for Molecular Life Sciences [Radboudumc 10], medicine.anatomical_structure, 030220 oncology & carcinogenesis, Reherniation, Original Article, Female, Ramirez, Tomography, X-Ray Computed, business, Body morphometrics, Abdominal surgery
Abstract: Background The component separation technique (CST) is considered an excellent technique for complex ventral hernia repair. However, postoperative infectious complications and reherniation rates are significant. Risk factor analysis for postoperative complication and reherniation has focused mostly on patient history and co-morbidity and shows equivocal results. The use of abdominal morphometrics derived from CT scans to assist in risk assessment seems promising. The aim of this study is to determine the predictability of reherniation and surgical site infections (SSI) using pre-operative CT measurements. Methods Electronic patient records were searched for patients who underwent CST between 2000 and 2013 and had a pre-operative CT scan available. Visceral fat volume (VFV), subcutaneous fat volume (SFV), loss of domain (LOD), rectus thickness and width (RT, RW), abdominal volume, hernia sac volume, total fat volume (TFV), sagittal distance (SD) and waist circumference (WC) were measured or calculated. Relevant variables were entered in multivariate regression analysis to determine their effect on reherniation and SSI as separate outcomes. Results Sixty-five patients were included. VFV (p = 0.025, OR = 1.65) was a significant predictor regarding reherniation. Hernia sac volume (p = 0.020, OR = 2.10) and SFV per 1000 cm3 (p = 0.034, OR = 0.26) were significant predictors of SSI. Conclusion Visceral fat volume, subcutaneous fat volume and hernia sac volume derived from CT scan measurements may be used to predict reherniation and SSI in patients undergoing complex ventral hernia repair using CST. These findings may aid in optimizing patient-tailored preoperative risk assessment.
Published: 2019
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25. Management of complex ventral hernias: results of an international survey

Author: Nicholas J. Slater, Camiel Rosman, L. Knaapen, B Matthews, Harry van Goor, and O.R. Buyne
Subjects: Adult, Male, medicine.medical_specialty, Internationality, Percutaneous, AcademicSubjects/MED00910, Attitude of Health Personnel, medicine.medical_treatment, 030230 surgery, Preoperative care, Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Practice Patterns, Physicians', Laparoscopy, Prospective cohort study, Herniorrhaphy, Aged, medicine.diagnostic_test, business.industry, General surgery, General Medicine, Middle Aged, Surgical Mesh, Hernia repair, Hernia, Ventral, Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10], Reconstructive and regenerative medicine Radboud Institute for Molecular Life Sciences [Radboudumc 10], Surgical mesh, Health Care Surveys, 030220 oncology & carcinogenesis, Ventral hernia, Smoking cessation, Female, Original Article, AcademicSubjects/MED00010, business
Abstract: Background The surgical treatment of patients with complex ventral hernias is challenging. The aim of this study was to present an international overview of expert opinions on current practice. Methods A survey questionnaire was designed to investigate preoperative risk management, surgical approach and mesh choice in patients undergoing complex hernias repair, and treatment strategies for infected meshes. Geographical location of practice, experience and annual volumes of the surgeons were compared. Results Of 408 surgeons, 234 (57.4 per cent) were practising in the USA, 116 (28.4 per cent) in Europe, and 58 (14.2 per cent) in other countries. Some 412 of 418 surgeons (98.6 per cent) performed open repair and 322 of 416 (77.4 per cent) performed laparoscopic repair. Most recommended preoperative work-up/lifestyle changes such as smoking cessation (319 of 398, 80.2 per cent) and weight loss (254 of 399, 63.7 per cent), but the consequences of these strategies varied. American surgeons and less experienced surgeons were stricter. Antibiotics were given at least 1 h before surgery by 295 of 414 respondents (71.3 per cent). Synthetic and biological meshes were used equally in contaminated primary hernia repair, whereas for recurrent hernia repair synthetic mesh was used in a clean environment and biological or no mesh in a contaminated environment. American surgeons and surgeons with less experience preferred biological mesh in contaminated environments significantly more often. Percutaneous drainage and antibiotics were the first steps recommended in treating mesh infection. In the presence of sepsis, most surgeons favoured synthetic mesh explantation and further repair with biological mesh. Conclusion There remains a paucity of good-quality evidence in dealing with these hernias, leading to variations in management. Patient optimization and issues related to mesh choice and infections require well designed prospective studies., This manuscript displays a good overview of current practice among difficult subjects in ventral hernia repair on which limited guidelines exist in two continents (Europe and USA). Based on our findings we would recommend that more attention should be paid on pre-operative optimization and specifically pre-operative diabetic control and adequate administration of antibiotic prophylaxis. Prehabilitation programs should be implemented together with patient education on the importance of risk reduction and the impact of complications. Reaching goals set to optimize patients before hernia surgery should be a quality control parameter. The use of biologic mesh in ventral hernia repair should be critically appraised. To improve adherence to guidelines and protocol decision tools, guideline training, easy ways of data sharing, feedback loops and apps may be helpful. Since there is a gap in knowledge concerning mesh infection (abscess) a standardized animal model needs to be developed to assess different treatment options and analyze different meshes for their susceptibility to infection and the ability to clear an infection. Lack of high quality evidence This survey provided a good overview of current practice among difficult subjects in ventral hernia repair on which limited guidelines exist in two continents (Europe and USA). Based on the findings, the authors recommend that more attention should be paid to preoperative optimization, specifically preoperative diabetic control and adequate antibiotic prophylaxis. Prehabilitation programmes should be implemented together with patient education on the importance of risk reduction and the impact of complications. Reaching goals set to optimize patients before hernia surgery should be a quality control parameter. The use of biological mesh in ventral hernia repair should be appraised critically. To improve adherence to guidelines and protocol decision tools, guideline training, easy ways of data-sharing, feedback loops and apps may be helpful.
Published: 2021
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26. Management of complex ventral hernias: results of an international survey

Author: Knaapen, L., Buyne, O.R., Slater, N.J., Matthews, B., Goor, H. van, Rosman, C., Knaapen, L., Buyne, O.R., Slater, N.J., Matthews, B., Goor, H. van, and Rosman, C.
Abstract: Contains fulltext : 239049.pdf (Publisher’s version ) (Open Access), BACKGROUND: The surgical treatment of patients with complex ventral hernias is challenging. The aim of this study was to present an international overview of expert opinions on current practice. METHODS: A survey questionnaire was designed to investigate preoperative risk management, surgical approach and mesh choice in patients undergoing complex hernias repair, and treatment strategies for infected meshes. Geographical location of practice, experience and annual volumes of the surgeons were compared. RESULTS: Of 408 surgeons, 234 (57.4 per cent) were practising in the USA, 116 (28.4 per cent) in Europe, and 58 (14.2 per cent) in other countries. Some 412 of 418 surgeons (98.6 per cent) performed open repair and 322 of 416 (77.4 per cent) performed laparoscopic repair. Most recommended preoperative work-up/lifestyle changes such as smoking cessation (319 of 398, 80.2 per cent) and weight loss (254 of 399, 63.7 per cent), but the consequences of these strategies varied. American surgeons and less experienced surgeons were stricter. Antibiotics were given at least 1 h before surgery by 295 of 414 respondents (71.3 per cent). Synthetic and biological meshes were used equally in contaminated primary hernia repair, whereas for recurrent hernia repair synthetic mesh was used in a clean environment and biological or no mesh in a contaminated environment. American surgeons and surgeons with less experience preferred biological mesh in contaminated environments significantly more often. Percutaneous drainage and antibiotics were the first steps recommended in treating mesh infection. In the presence of sepsis, most surgeons favoured synthetic mesh explantation and further repair with biological mesh. CONCLUSION: There remains a paucity of good-quality evidence in dealing with these hernias, leading to variations in management. Patient optimization and issues related to mesh choice and infections require well designed prospective studies. Publisher: Abstract available from t
Published: 2021

27. Imaging based flowchart for gallbladder polyp evaluation

Author: Wennmacker, Sarah Z., primary, de Savornin Lohman, Elise A.J., additional, de Reuver, Philip R., additional, Drenth, Joost P.H., additional, van der Post, Rachel S., additional, Nagtegaal, Iris D., additional, Hermans, John J., additional, van Laarhoven, Cornelis J.H.M., additional, Schreinemakers, Jennifer M.J., additional, Heisterkamp, Joos, additional, Hansson, Bibi, additional, Buyne, Otmar, additional, Nieuwenhuijs, Vincent B., additional, Spillenaar Bilgen, Ernst Jan, additional, and Bosscha, Koop, additional
Published: 2021
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28. Management of complex ventral hernias: results of an international survey

Author: Knaapen, L, primary, Buyne, O, additional, Slater, N, additional, Matthews, B, additional, Goor, H, additional, and Rosman, C, additional
Published: 2021
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29. Right-Sided Bochdalek Hernia with Cecum Perforation

Author: Natroshvili, Tina, primary, Faraj, Dashti, additional, Janssen, Emmy, additional, Goor, Harry van, additional, Hartman, Melanie, additional, Buyne, Otmar R., additional, and Natroshvili, Tina, additional
Published: 2020
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30. Syntheticvsbiologic mesh for the repair and prevention of parastomal hernia

Author: L. Knaapen, Nicholas J. Slater, H. van Goor, and O.R. Buyne
Subjects: Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10], 03 medical and health sciences, medicine.medical_specialty, Reconstructive and regenerative medicine Radboud Institute for Molecular Life Sciences [Radboudumc 10], 0302 clinical medicine, business.industry, 030220 oncology & carcinogenesis, Medicine, 030230 surgery, business, Parastomal hernia, Surgery
Abstract: Contains fulltext : 181803.pdf (Publisher’s version ) (Open Access)
Published: 2017
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31. A multicentre randomized non-inferiority trial comparing usual care to restrictive strategy for use of cholecystectomy in patients with gallstones and abdominal pain (SECURE trial)

Author: Marja A. Boermeester, J.P.H. Drenth, C.J.H.M. van Laarhoven, Sarah Z. Wennmacker, O.R. Buyne, Jeroen M. Jansen, P.R. de Reuver, Carmen S S Latenstein, A. H. van Dijk, D. Boerma, P. Van Steenvoorde, Sandra C. Donkervoort, Gert P. Westert, Marcel G. W. Dijkgraaf, Hein B A C Stockmann, Vincent B. Nieuwenhuijs, K. In 't Hof, H. Schaap, Q. A. J. Eijsbouts, and Joos Heisterkamp
Subjects: medicine.medical_specialty, Abdominal pain, Hepatology, business.industry, medicine.medical_treatment, General surgery, Gastroenterology, Gallstones, medicine.disease, Usual care, medicine, Non inferiority trial, Cholecystectomy, In patient, medicine.symptom, business
Published: 2020
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32. A multicentre randomized non-inferiority trial comparing usual care to restrictive strategy for use of cholecystectomy in patients with gallstones and abdominal pain (SECURE trial)

Author: Wennmacker, S., primary, Van Dijk, A., additional, De Reuver, P., additional, Latenstein, C., additional, Buyne, O., additional, Donkervoort, S., additional, Eijsbouts, Q., additional, Heisterkamp, J., additional, In 't Hof, K., additional, Jansen, J., additional, Nieuwenhuijs, V., additional, Schaap, H., additional, Van Steenvoorde, P., additional, Stockmann, H., additional, Boerma, D., additional, Westert, G., additional, Drenth, J., additional, Dijkgraaf, M., additional, Boermeester, M., additional, and Van Laarhoven, C., additional
Published: 2020
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33. Pre-operative CT scan measurements for predicting complications in patients undergoing complex ventral hernia repair using the component separation technique

Author: Winters, H., primary, Knaapen, L., additional, Buyne, O. R., additional, Hummelink, S., additional, Ulrich, D. J. O., additional, van Goor, H., additional, van Geffen, E., additional, and Slater, N. J., additional
Published: 2019
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34. Efficacy and Safety of Ultrapure Alginate-Based Anti-Adhesion Gel in Experimental Peritonitis

Author: Roger M. L. M. Lomme, O.R. Buyne, Thijs Hendriks, Ankit A. Chaturvedi, and H. van Goor
Subjects: Male, Microbiology (medical), Abdominal Abscess, Alginates, Bacterial Peritonitis, Peritonitis, Tissue Adhesions, medicine.disease_cause, Microbiology, Glucuronic Acid, medicine, Animals, Rats, Wistar, Abscess, Escherichia coli, Feces, biology, business.industry, Hexuronic Acids, Body Weight, Adhesion, Adhesion barrier, biology.organism_classification, medicine.disease, Rats, Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10], Disease Models, Animal, Reconstructive and regenerative medicine Radboud Institute for Molecular Life Sciences [Radboudumc 10], Infectious Diseases, Surgery, Bacteroides fragilis, business, Gels
Abstract: Item does not contain fulltext BACKGROUND: Intra-abdominal infection may lead to adhesion and abscess formation. An adhesion barrier can reduce these complications but also aggravate intra-peritoneal infection, causing the opposite effects. The fear of infection propagation has limited clinical adhesion barrier use in a contaminated or infected abdomen. This study evaluated both adhesion and abscess reduction and infection propagation of a new ultrapure alginate-based anti-adhesive barrier gel in a rat peritonitis model. METHODS: In 64 male Wistar rats, bacterial peritonitis was induced via intra-abdominal injection of a mixture of sterile feces, 10(5) colony-forming units (CFU) of Escherichia coli, and 10(4) CFU of Bacteroides fragilis. Surgical debridement and peritoneal lavage were performed 1 h after inoculation. Animals were randomly allocated in equal numbers to a control group or an alginate gel group. Animals were sacrificed on day five post-operatively. Death and the presence and size of intra-abdominal abscesses were noted, and adhesions were scored. All outcomes were compared in the two groups. RESULTS: Seventeen rats (27%) died prematurely without any difference between the groups. Of the surviving rats in the alginate gel group, 88% developed abscesses vs. 100% of the control group. There was no significant difference in the abscess scores or incidence rates of adhesion formation between the groups. The adhesion scores were lower for the alginate gel group compared with control animals (p=0.04). CONCLUSION: Ultrapure alginate gel reduces adhesion severity but not abscesses. The gel seemed to be safe, not aggravating intra-peritoneal infection in this abdominal infection model.
Published: 2015
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35. Erratum: Antimicrobials: A global alliance for optimizing their rational use in intra-abdominal infections (AGORA). [World J Emerg Surg. 11, (2016) (33)] DOI: 10.1186/s13017-016-0089-y

Author: Sartelli, M., Weber, D. G., Ruppé, E., Bassetti, M., Wright, B. J., Ansaloni, L., Catena, F., Coccolini, F., Abu-Zidan, F. M., Coimbra, R., Moore, E. E., Moore, F. A., Maier, R. V., De Waele, J. J., Kirkpatrick, A. W., Griffiths, E. A., Eckmann, C., Brink, A. J., Mazuski, J. E., May, A. K., Sawyer, R. G., Mertz, D., Montravers, P., Kumar, A., Roberts, J. A., Vincent, J. L., Watkins, R. R., Lowman, W., Spellberg, B., Abbott, I. J., Adesunkanmi, A. K., Al-Dahir, S., Al-Hasan, M. N., Agresta, F., Althani, A. A., Ansari, S., Ansumana, R., Augustin, G., Bala, M., Balogh, Z. J., Baraket, O., Bhangu, A., Beltrán, M. A., Bernhard, M., Biffl, W. L., Boermeester, M. A., Brecher, S. M., Cherry-Bukowiec, J. R., Buyne, O. R., Cainzos, M. A., Cairns, K. A., Camacho-Ortiz, A., Chandy, S. J., Che Jusoh, A., Chichom-Mefire, A., Colijn, C., Corcione, F., Cui, Y., Curcio, D., Delibegovic, S., Demetrashvili, Z., De Simone, B., Dhingra, S., Diaz, J. J., Di Carlo, I., Dillip, A., Di Saverio, S., Doyle, M. P., Dorj, G., Dogjani, A., Dupont, H., Eachempati, S. R., Enani, M. A., Egiev, V. N., Elmangory, M. M., Ferrada, P., Fitchett, J. R., Fraga, G. P., Guessennd, N., Giamarellou, H., Ghnnam, W., Gkiokas, G., Goldberg, S. R., Gomes, C. A., Gomi, H., Guzmán-Blanco, M., Haque, M., Hansen, S., Hecker, A., Heizmann, W. R., Herzog, T., Hodonou, A. M., Hong, S. K., Kafka-Ritsch, R., Kaplan, L. J., Kapoor, G., Karamarkovic, A., Kees, M. G., Kenig, J., Kiguba, R., Kim, P. K., Kluger, Y., Khokha, V., Koike, K., Kok, K. Y., Kong, V., Knox, M. C., Inaba, K., Isik, A., Iskandar, K., Ivatury, R. R., Labbate, M., Labricciosa, F. M., Laterre, P. F., Latifi, R., Lee, J. G., Lee, Y. R., Leone, M., Leppaniemi, A., Li, Y., Liang, S. Y., Loho, T., Maegele, M., Malama, S., Marei, H. E., Martin-Loeches, I., Marwah, S., Massele, A., Mcfarlane, M., Melo, R. B., Negoi, I., Nicolau, D. P., Nord, C. E., Ofori-Asenso, R., Omari, A. H., Ordonez, C. A., Ouadii, M., Pereira Júnior, G. A., Piazza, D., Pupelis, G., Rawson, T. M., Rems, M., Rizoli, S., Rocha, C., Sakakushev, B., Sanchez-Garcia, M., Sato, N., Segovia Lohse, H. A., Sganga, G., Siribumrungwong, B., Shelat, V. G., Soreide, K., Soto, R., Talving, P., Tilsed, J. V., Timsit, J. F., Trueba, G., Trung, N. T., Ulrych, J., van Goor, H., Vereczkei, A., Vohra, R. S., Wani, I., Uhl, W., Xiao, Y., Yuan, K. C., Zachariah, S. K., Zahar, J. R., Zakrison, T. L., Corcione, A., Melotti, R. M., Viscoli, C., Viale, P., Sartelli, M., Weber, D. G., Ruppé, E., Bassetti, M., Wright, B. J., Ansaloni, L., Catena, F., Coccolini, F., Abu-Zidan, F. M., Coimbra, R., Moore, E. E., Moore, F. A., Maier, R. V., De Waele, J. J., Kirkpatrick, A. W., Griffiths, E. A., Eckmann, C., Brink, A. J., Mazuski, J. E., May, A. K., Sawyer, R. G., Mertz, D., Montravers, P., Kumar, A., Roberts, J. A., Vincent, J. L., Watkins, R. R., Lowman, W., Spellberg, B., Abbott, I. J., Adesunkanmi, A. K., Al-Dahir, S., Al-Hasan, M. N., Agresta, F., Althani, A. A., Ansari, S., Ansumana, R., Augustin, G., Bala, M., Balogh, Z. J., Baraket, O., Bhangu, A., Beltrán, M. A., Bernhard, M., Biffl, W. L., Boermeester, M. A., Brecher, S. M., Cherry-Bukowiec, J. R., Buyne, O. R., Cainzos, M. A., Cairns, K. A., Camacho-Ortiz, A., Chandy, S. J., Che Jusoh, A., Chichom-Mefire, A., Colijn, C., Corcione, F., Cui, Y., Curcio, D., Delibegovic, S., Demetrashvili, Z., De Simone, B., Dhingra, S., Diaz, J. J., Di Carlo, I., Dillip, A., Di Saverio, S., Doyle, M. P., Dorj, G., Dogjani, A., Dupont, H., Eachempati, S. R., Enani, M. A., Egiev, V. N., Elmangory, M. M., Ferrada, P., Fitchett, J. R., Fraga, G. P., Guessennd, N., Giamarellou, H., Ghnnam, W., Gkiokas, G., Goldberg, S. R., Gomes, C. A., Gomi, H., Guzmán-Blanco, M., Haque, M., Hansen, S., Hecker, A., Heizmann, W. R., Herzog, T., Hodonou, A. M., Hong, S. K., Kafka-Ritsch, R., Kaplan, L. J., Kapoor, G., Karamarkovic, A., Kees, M. G., Kenig, J., Kiguba, R., Kim, P. K., Kluger, Y., Khokha, V., Koike, K., Kok, K. Y., Kong, V., Knox, M. C., Inaba, K., Isik, A., Iskandar, K., Ivatury, R. R., Labbate, M., Labricciosa, F. M., Laterre, P. F., Latifi, R., Lee, J. G., Lee, Y. R., Leone, M., Leppaniemi, A., Li, Y., Liang, S. Y., Loho, T., Maegele, M., Malama, S., Marei, H. E., Martin-Loeches, I., Marwah, S., Massele, A., Mcfarlane, M., Melo, R. B., Negoi, I., Nicolau, D. P., Nord, C. E., Ofori-Asenso, R., Omari, A. H., Ordonez, C. A., Ouadii, M., Pereira Júnior, G. A., Piazza, D., Pupelis, G., Rawson, T. M., Rems, M., Rizoli, S., Rocha, C., Sakakushev, B., Sanchez-Garcia, M., Sato, N., Segovia Lohse, H. A., Sganga, G., Siribumrungwong, B., Shelat, V. G., Soreide, K., Soto, R., Talving, P., Tilsed, J. V., Timsit, J. F., Trueba, G., Trung, N. T., Ulrych, J., van Goor, H., Vereczkei, A., Vohra, R. S., Wani, I., Uhl, W., Xiao, Y., Yuan, K. C., Zachariah, S. K., Zahar, J. R., Zakrison, T. L., Corcione, A., Melotti, R. M., Viscoli, C., and Viale, P.
Subjects: Settore MED/18 - CHIRURGIA GENERALE, Surgery, Emergency Medicine
Published: 2017

36. Pre-operative CT scan measurements for predicting complications in patients undergoing complex ventral hernia repair using the component separation technique

Author: Winters, H., Knaapen, L., Buyne, O.R., Hummelink, S.L.M., Ulrich, D.J.O., Goor, H. van, Geffen, E. van, Slater, N.J., Winters, H., Knaapen, L., Buyne, O.R., Hummelink, S.L.M., Ulrich, D.J.O., Goor, H. van, Geffen, E. van, and Slater, N.J.
Abstract: Contains fulltext : 203375.pdf (publisher's version ) (Open Access)
Published: 2019

37. Restrictive strategy versus usual care for cholecystectomy in patients with gallstones and abdominal pain (SECURE): a multicentre, randomised, parallel-arm, non-inferiority trial

Author: Dijk, A.H van, Wennmacker, S.Z., Reuver, P.R. de, Latenstein, C.S.S., Buyne, O.R., Donkervoort, Sandra C., Schaap, H.M, Westert, G.P., Drenth, J.P., Boermeester, Marja A., Laarhoven, C.J.H.M. van, Dijk, A.H van, Wennmacker, S.Z., Reuver, P.R. de, Latenstein, C.S.S., Buyne, O.R., Donkervoort, Sandra C., Schaap, H.M, Westert, G.P., Drenth, J.P., Boermeester, Marja A., and Laarhoven, C.J.H.M. van
Abstract: Contains fulltext : 204615.pdf (publisher's version ) (Closed access)
Published: 2019

38. Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) (vol 11, 33, 2016)

Author: Sartelli, M., Weber, D. G., Ruppe, E., Bassetti, M., Wright, B. J., Ansaloni, L., Catena, F., Coccolini, F., Abu-Zidan, F. M., Coimbra, R., Moore, E. E., Moore, F. A., Maier, R. V., De Waele, J. J., Kirkpatrick, A. W., Griffiths, E. A., Eckmann, C., Brink, A. J., Mazuski, J. E., May, A. K., Sawyer, R. G., Mertz, D., Montravers, P., Kumar, A., Roberts, J. A., Vincent, L., Watkins, R. R., Lowman, W., Spellberg, B., Abbott, I. J., Adesunkanmi, A. K., Al-Dahir, S., Al-Hasan, M. N., Agresta, F., Althani, A. A., Ansari, S., Ansumana, R., Augustin, G., Bala, M., Balogh, Z. J., Baraket, O., Bhangu, A., Beltrán, Anna Maria, Bernhard, M., Biffl, W. L., Boermeester, M. A., Brecher, S. M., Cherry-Bukowiec, J. R., Buyne, O. R., Cainzos, M. A., Cairns, K. A., Camacho-Ortiz, A., Chandy, S. J., Jusoh, A. Che, Chichom-Mefire, A., Colijn, C., Corcione, F., Cui, Y., Curcio, D., Delibegovic, S., Demetrashvili, Z., De Simone, B., Dhingra, S., Diaz, J. J., Di Carlo, I., Dillip, A., Di Saverio, S., Doyle, M. P., Dorj, G., Dogjani, A., Dupont, H., Eachempati, S. R., Enani, M. A., Egiev, V. N., Elmangory, M. M., Ferrada, P., Fitchett, J. R., Fraga, G. P., Guessennd, N., Giamarellou, H., Ghnnam, W., Gkiokas, G., Goldberg, S. R., Gomes, C. A., Gomi, H., Guzman-Blanco, M., Haque, M., Hansen, S., Hecker, A., Heizmann, W. R., Herzog, T., Hodonou, A. M., Hong, S. K., Kafka-Ritsch, R., Kaplan, L. J., Kapoor, G., Karamarkovic, A., Kees, M. G., Kenig, J., Kiguba, R., Kim, P. K., Kluger, Y., Khokha, V., Koike, K., Kok, K. Y., Kong, V., Knox, M. C., Inaba, K., Isik, A., Iskandar, K., Ivatury, R. R., Labbate, M., Labricciosa, F. M., Laterre, P. F., Latifi, R., Lee, J. G., Lee, Y. R., Leone, M., Leppaniemi, A., Li, Y., Liang, S. Y., Loho, T., Maegele, M., Malama, S., Marei, H. E., Martin-Loeches, I., Marwah, S., Massele, A., McFarlane, M., Melo, R. B., Negoi, I., Nicolau, D. P., Nord, C. E., Ofori-Asenso, R., Omari, A. H., Ordonez, C. A., Ouadii, M., Pereira Junior, G. A., Piazza, D., Pupelis, G., Rawson, T. M., Rems, M., Rizoli, S., Rocha, C., Sakakushev, B., Sanchez-Garcia, M., Sato, N., Segovia Lohse, H. A., Sganga, G., Siribumrungwong, B., Shelat, V. G., Soreide, K., Soto, R., Talving, P., Tilsed, J. V., Timsit, J. F., Trueba, G., Trung, N. T., Ulrych, J., Van Goor, H., Vereczkei, A., Vohra, R. S., Wani, I., Uhl, W., Xiao, Y., Yuan, K. C., Zachariah, S. K., Zahar, J. R., Zakrison, T. L., Corcione, A., Melotti, R. M., Viscoli, C., Viale, P., Universita 'La Sapienza' Roma (Istituto CNR), Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA), Universidade de Aveiro, Laboratoire matériaux et microélectronique de Provence (L2MP), Université Paul Cézanne - Aix-Marseille 3-Université de Provence - Aix-Marseille 1-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur de Côte d'Ivoire, Réseau International des Instituts Pasteur (RIIP), National Defence University of Malaysia [Kuala Lumpur], Max Planck Institute for the Physics of Complex Systems (MPI-PKS), Max-Planck-Gesellschaft, Center for Plant Molecular Biology, Plant Physiology, and Biophysical Chemistry, University of Tübingen, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Dipartimento di Fisica 'Giuseppe Occhialini' = Department of Physics 'Giuseppe Occhialini' [Milano-Bicocca], Università degli Studi di Milano-Bicocca = University of Milano-Bicocca (UNIMIB), Atmospheric and Environmental Research, Inc. (AER), Zhejiang University, Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], INSB-INSB-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Università degli Studi di Milano-Bicocca [Milano] (UNIMIB), and COMBE, Isabelle
Subjects: [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, Carbapenems, Antimicrobial Resistance, Invasive Candidiasis, Methicillin Resistant Staphylococcus Aureus, Tigecycline, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract: International audience; Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients.The cornerstones in the management of complicated IAIs are timely effective source control with appropriate antimicrobial therapy. Empiric antimicrobial therapy is important in the management of intra-abdominal infections and must be broad enough to cover all likely organisms because inappropriate initial antimicrobial therapy is associated with poor patient outcomes and the development of bacterial resistance.The overuse of antimicrobials is widely accepted as a major driver of some emerging infections (such as C. difficile), the selection of resistant pathogens in individual patients, and for the continued development of antimicrobial resistance globally. The growing emergence of multi-drug resistant organisms and the limited development of new agents available to counteract them have caused an impending crisis with alarming implications, especially with regards to Gram-negative bacteria.An international task force from 79 different countries has joined this project by sharing a document on the rational use of antimicrobials for patients with IAIs. The project has been termed AGORA (Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections). The authors hope that AGORA, involving many of the world's leading experts, can actively raise awareness in health workers and can improve prescribing behavior in treating IAIs.
Published: 2017
Full Text: View/download PDF

39. Erratum: Antimicrobials: A global alliance for optimizing their rational use in intra-abdominal infections (AGORA). [World J Emerg Surg. 11, (2016) (33)] DOI: 10.1186/s13017-016-0089-y

Author: Sartelli, M, Weber, DG, Ruppé, E, Bassetti, M, Wright, BJ, Ansaloni, L, Catena, F, Coccolini, F, Abu-Zidan, FM, Coimbra, R, Moore, EE, Moore, FA, Maier, RV, De Waele, JJ, Kirkpatrick, AW, Griffiths, EA, Eckmann, C, Brink, AJ, Mazuski, JE, May, AK, Sawyer, RG, Mertz, D, Montravers, P, Kumar, A, Roberts, JA, Vincent, JL, Watkins, RR, Lowman, W, Spellberg, B, Abbott, IJ, Adesunkanmi, AK, Al-Dahir, S, Al-Hasan, MN, Agresta, F, Althani, AA, Ansari, S, Ansumana, R, Augustin, G, Bala, M, Balogh, ZJ, Baraket, O, Bhangu, A, Beltrán, MA, Bernhard, M, Biffl, WL, Boermeester, MA, Brecher, SM, Cherry-Bukowiec, JR, Buyne, OR, Cainzos, MA, Cairns, KA, Camacho-Ortiz, A, Chandy, SJ, Che Jusoh, A, Chichom-Mefire, A, Colijn, C, Corcione, F, Cui, Y, Curcio, D, Delibegovic, S, Demetrashvili, Z, De Simone, B, Dhingra, S, Diaz, JJ, Di Carlo, I, Dillip, A, Di Saverio, S, Doyle, MP, Dorj, G, Dogjani, A, Dupont, H, Eachempati, SR, Enani, MA, Egiev, VN, Elmangory, MM, Ferrada, P, Fitchett, JR, Fraga, GP, Guessennd, N, Giamarellou, H, Ghnnam, W, Gkiokas, G, Goldberg, SR, Gomes, CA, Gomi, H, Guzmán-Blanco, M, Haque, M, Hansen, S, Hecker, A, Heizmann, WR, Herzog, T, Hodonou, AM, Hong, SK, Kafka-Ritsch, R, Kaplan, LJ, Kapoor, G, Karamarkovic, A, Kees, MG, Kenig, J, and Kiguba, R
Subjects: Surgery
Abstract: © The Author(s). The original article [1] contains an error whereby a co-author, Boris Sakakushev has their family name spelt incorrectly as 'Sakakhushev'. The authors would therefore like it known that the correct spelling of the family name is 'Sakakushev'.
Published: 2017

40. Erratum to: Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)

Author: Kuo Ching Yuan, Sujith J Chandy, Katia Iskandar, Michael McFarlane, Nathalie Guessennd, M. Bala, Timothy M. Rawson, Francesco M. Labricciosa, Sandro Rizoli, Stephen M. Brecher, Alain Chichom-Mefire, Richard Ofori-Asenso, Rao R. Ivatury, Miguel Sanchez-Garcia, Ngo Tat Trung, Carlos Augusto Gomes, Angel Dillip, Yunfeng Cui, Yousheng Li, Antonio Corcione, Tonny Loho, F. Corcione, Vishalkumar G Shelat, Federico Coccolini, Helen Giamarellou, W. R. Heizmann, Richard R. Watkins, Zaza Demetrashvili, Asma Althani, Iain J. Abbott, Andreas Hecker, Addison K. May, Adrián Camacho-Ortiz, Wagih Ghnnam, Sydney Malama, Kenneth Y.Y. Kok, Jonathan Tilsed, Shamshul Ansari, Garima Kapoor, Young R. Lee, B. Sakakushev, A R K Adesunkanmi, Fausto Catena, Kjetil Søreide, Andrew W. Kirkpatrick, Rifat Latifi, Daniel Curcio, Marc Leone, Norio Sato, Arda Isik, Robert G. Sawyer, Gereltuya Dorj, Mouaqit Ouadii, F. A. Moore, Miran Rems, Jason A. Roberts, Ravinder S. Vohra, Fikri M. Abu-Zidan, András Vereczkei, Zsolt J. Balogh, Georgios Gkiokas, Sara Al-Dahir, Walter L. Biffl, Raul Coimbra, Sonja Hansen, Mainul Haque, Kenji Inaba, Ferdinando Agresta, Jean-Ralph Zahar, Miguel Caínzos, Ari Leppäniemi, Pierre-François Laterre, S. Di Saverio, Jean-François Timsit, Vladimir Khokha, Gabriele Sganga, Luca Ansaloni, Brian J. Wright, Jean Louis Vincent, Agron Dogjani, Jan Ulrych, Reinhold Kafka-Ritsch, Paula Ferrada, Sanjay Marwah, Rashid Ansumana, Swati Dhingra, Lewis J. Kaplan, Warren Lowman, Aneel Bhangu, Matthew C Knox, Ionut Negoi, Yonghong Xiao, Gabriel Trueba, H. A. Segovia Lohse, Claudio Rocha, Waldemar Uhl, Joseph R Fitchett, Gustavo Pereira Fraga, Michael P. Doyle, Jae G. Lee, Goran Augustin, Valery N. Egiev, G. A. Pereira Júnior, Jakub Kenig, Ashwani Kumar, Abdelkarim H. Omari, Peter K. Kim, Oussema Baraket, Suk-Kyung Hong, Stephen Y. Liang, Ernest E. Moore, Torsten Herzog, Mutasim M. Elmangory, Victor Y. Kong, Hervé Dupont, John E. Mazuski, H. van Goor, Pierluigi Viale, Kelly A. Cairns, Guntars Pupelis, Martin G. Kees, Philippe Montravers, Christian Eckmann, R. V. Maier, Yoram Kluger, Marja A. Boermeester, Carl Erik Nord, Ronald Kiguba, Etienne Ruppé, Harumi Gomi, Hany E. Marei, Ewen A. Griffiths, J. J. De Waele, Mushira Enani, Ignacio Martin-Loeches, Boonying Siribumrungwong, B. De Simone, Rodolfo Soto, Caroline Colijn, Samir Delibegovic, Stephanie Goldberg, Marcelo A. Beltrán, Rita Maria Melotti, Matteo Bassetti, Adrien Hodonou, Marc Maegele, Sanoop K. Zachariah, Jill R. Cherry-Bukowiec, Dominik Mertz, Claudio Viscoli, Diego Piazza, Massimo Sartelli, O.R. Buyne, Manuel Guzman-Blanco, Majdi N. Al-Hasan, Peep Talving, Michael Bernhard, Imtiaz Wani, Renato Bessa Melo, I. Di Carlo, Tanya L. Zakrison, Dieter G. Weber, Soumitra R. Eachempati, Carlos A. Ordoñez, Amos Massele, Kaoru Koike, Aleksandar Karamarkovic, Adrian Brink, Brad Spellberg, Maurizio Labbate, David P. Nicolau, Jose J. Diaz, A. Che Jusoh, and Engineering & Physical Science Research Council (EPSRC)
Subjects: medicine.medical_specialty, International Cooperation, lcsh:Surgery, Peritonitis, Microbial Sensitivity Tests, Tigecycline, 030230 surgery, medicine.disease_cause, Emerging and Re-emerging Infectious Diseases, 03 medical and health sciences, 0302 clinical medicine, Antibiotic resistance, Anti-Infective Agents, medicine, Humans, Agora, Intensive care medicine, computer.programming_language, Science & Technology, business.industry, Abdominal Infection, lcsh:Medical emergencies. Critical care. Intensive care. First aid, Drug Resistance, Microbial, 030208 emergency & critical care medicine, lcsh:RD1-811, lcsh:RC86-88.9, Prognosis, medicine.disease, Antimicrobial, Methicillin-resistant Staphylococcus aureus, Spelling, 3. Good health, Emergency Medicine, Intraabdominal Infections, Surgery, Artificial intelligence, Erratum, business, computer, Life Sciences & Biomedicine, medicine.drug
Abstract: Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients. The cornerstones in the management of complicated IAIs are timely effective source control with appropriate antimicrobial therapy. Empiric antimicrobial therapy is important in the management of intra-abdominal infections and must be broad enough to cover all likely organisms because inappropriate initial antimicrobial therapy is associated with poor patient outcomes and the development of bacterial resistance. The overuse of antimicrobials is widely accepted as a major driver of some emerging infections (such as C. difficile), the selection of resistant pathogens in individual patients, and for the continued development of antimicrobial resistance globally. The growing emergence of multi-drug resistant organisms and the limited development of new agents available to counteract them have caused an impending crisis with alarming implications, especially with regards to Gram-negative bacteria. An international task force from 79 different countries has joined this project by sharing a document on the rational use of antimicrobials for patients with IAIs. The project has been termed AGORA (Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections). The authors hope that AGORA, involving many of the world's leading experts, can actively raise awareness in health workers and can improve prescribing behavior in treating IAIs.
Published: 2017

41. Antimicrobials : a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)

Author: Richard R. Watkins, Adrien Hodonou, Brad Spellberg, Fausto Catena, Marc Maegele, Sanoop K. Zachariah, András Vereczkei, Katia Iskandar, Jill R. Cherry-Bukowiec, Jean-Ralph Zahar, Shamshul Ansari, Luca Ansaloni, Addison K. May, Aneel Bhangu, Rao R. Ivatury, Sujith J Chandy, Joseph R Fitchett, Gustavo Pereira Fraga, Peep Talving, Tonny Loho, Amos Massele, Kaoru Koike, Marcelo A. Beltrán, Salomone Di Saverio, Zaza Demetrashvili, Isidoro Di Carlo, Rifat Latifi, Christian Eckmann, Miran Rems, Adrián Camacho-Ortiz, Dieter G. Weber, Majdi N. Al-Hasan, Manuel Guzman-Blanco, Soumitra R. Eachempati, Ravinder S. Vohra, Kjetil Søreide, Etienne Ruppé, Matteo Bassetti, Arda Isik, Andrew W. Kirkpatrick, Hany E. Marei, Gereltuya Dorj, Belinda De Simone, Aleksandar Karamarkovic, Adrian Brink, Jason A. Roberts, Caroline Colijn, Francesco M. Labricciosa, Mainul Haque, Frederick A. Moore, Michael Bernhard, Miguel Caínzos, Ari Leppäniemi, Sara Al-Dahir, Sonja Hansen, Maurizio Labbate, Boonying Siribumrungwong, Hervé Dupont, Rita Maria Melotti, Helen Giamarellou, Vishal G Shelat, Martin G. Kees, Rodolfo Soto, F. Corcione, Michael McFarlane, Kenji Inaba, Samir Delibegovic, Kuo Ching Yuan, David P. Nicolau, Gerson Alves Pereira Júnior, Jose J. Diaz, Dominik Mertz, Claudio Viscoli, Lewis J. Kaplan, George Gkiokas, Torsten Herzog, Alain Chichom-Mefire, Agron Dogjani, Jan Ulrych, Jan J. De Waele, Jean-François Timsit, Warren Lowman, Yunfeng Cui, Asmaa Althani, Yousheng Li, Diego Piazza, Staphanie R. Goldberg, Yoram Kluger, Carlos A. Ordoñez, Carl Erik Nord, Waldemar Uhl, O.R. Buyne, Imtiaz Wani, Wolfgang R. Heizmann, Valery N. Egiev, Timothy M. Rawson, Abdel K. Omari, Renato Bessa Melo, A R K Adesunkanmi, Miguel Sanchez-Garcia, Pierre-François Laterre, Vladimir Khokha, Harumi Gomi, Massimo Sartelli, Boris Sakakhushev, Ewen A. Griffiths, Ngo Tat Trung, Young R. Lee, Tanya L. Zakrison, Mushira Enani, Ignacio Martin-Loeches, Gabriele Sganga, Ionut Negoi, Carlos Augusto Gomes, Jakub Kenig, Ronald V. Maier, Norio Sato, Gabriel Trueba, Kelly A. Cairns, Claudio Rocha, Anand Kumar, Andreas Hecker, Fikri M. Abu-Zidan, Marja A. Boermeester, Michael P. Doyle, Peter K. Kim, Federico Coccolini, Paula Ferrada, Sandro Rizoli, Stephen M. Brecher, Robert G. Sawyer, Victory Kong, Jean Louis Vincent, Goran Augustin, Suk-Kyung Hong, Stephen Y. Liang, Helmut Alfredo Segovia Lohse, Walter L. Biffl, Reinhold Kafka-Ritsch, Jae Gil Lee, Ernest E. Moore, Sameer Dhingra, Miklosh Bala, Sydney Malama, Kenneth Y.Y. Kok, Oussama Baraket, Harry van Goor, Garima Kapoor, Philippe Montravers, Iain J. Abbott, Wagih Ghnnam, Angel Dillip, Raul Coimbra, Sanjay Marwah, Mouaqit Ouadii, Zsolt J. Balogh, Nathalie Guessennd, Richard Ofori-Asenso, Jonathan Tilsed, Antonio Corcione, Daniel Curcio, Marc Leone, Guntars Pupelis, Yonghong Xiao, Ferdinando Agresta, Mutasim M. Elmangory, Brian J. Wright, John E. Mazuski, Asri Che Jusoh, Perluigi Viale, Ronald Kiguba, Rashid Ansumana, Matthew C Knox, CHU Amiens-Picardie, 6th Department of Internal Medicine, Diagnostic and Therapeutic Center of Athens 'Hygeia', Department of Anesthesiology and Intensive Care, Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS), Hartford Hospital, Department of Laboratory Medicine, Karolinska Institutet [Stockholm], Equipe mobile d'infectiologie, CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service Microbiologie-Hygiène Hospitalière, Infectious Diseases, Università degli studi di Genova = University of Genoa (UniGe), Service d'anesthésie - réanimation chirurgicale [CHU Bichat], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7), Université libre de Bruxelles (ULB), Sartelli, Massimo, Weber, Dieter G., Ruppé, Etienne, Bassetti, Matteo, Wright, Brian J., Ansaloni, Luca, Catena, Fausto, Coccolini, Federico, Abu-Zidan, Fikri M., Coimbra, Raul, Moore, Ernest E., Moore, Frederick A., Maier, Ronald V., De Waele, Jan J., Kirkpatrick, Andrew W., Griffiths, Ewen A., Eckmann, Christian, Brink, Adrian J., Mazuski, John E., May, Addison K., Sawyer, Rob G., Mertz, Dominik, Montravers, Philippe, Kumar, Anand, Roberts, Jason A., Vincent, Jean-Loui, Watkins, Richard R., Lowman, Warren, Spellberg, Brad, Abbott, Iain J., Adesunkanmi, Abdulrashid Kayode, Al-Dahir, Sara, Al-Hasan, Majdi N., Agresta, Ferdinando, Althani, Asma A., Ansari, Shamshul, Ansumana, Rashid, Augustin, Goran, Bala, Miklosh, Balogh, Zsolt J., Baraket, Oussama, Bhangu, Aneel, Beltrán, Marcelo A., Bernhard, Michael, Biffl, Walter L., Boermeester, Marja A., Brecher, Stephen M., Cherry-Bukowiec, Jill R., Buyne, Otmar R., Cainzos, Miguel A., Cairns, Kelly A., Camacho-Ortiz, Adrian, Chandy, Sujith J., Che Jusoh, Asri, Chichom-Mefire, Alain, Colijn, Caroline, Corcione, Francesco, Cui, Yunfeng, Curcio, Daniel, Delibegovic, Samir, Demetrashvili, Zaza, De Simone, Belinda, Dhingra, Sameer, Diaz, José J., Di Carlo, Isidoro, Dillip, Angel, Di Saverio, Salomone, Doyle, Michael P., Dorj, Gereltuya, Dogjani, Agron, Dupont, Hervé, Eachempati, Soumitra R., Enani, Mushira Abdulaziz, Egiev, Valery N., Elmangory, Mutasim M., Ferrada, Paula, Fitchett, Joseph R., Fraga, Gustavo P., Guessennd, Nathalie, Giamarellou, Helen, Ghnnam, Wagih, Gkiokas, George, Goldberg, Staphanie R., Gomes, Carlos Augusto, Gomi, Harumi, Guzmán-Blanco, Manuel, Haque, Mainul, Hansen, Sonja, Hecker, Andrea, Heizmann, Wolfgang R., Herzog, Torsten, Hodonou, Adrien Montcho, Hong, Suk-Kyung, Kafka-Ritsch, Reinhold, Kaplan, Lewis J., Kapoor, Garima, Karamarkovic, Aleksandar, Kees, Martin G., Kenig, Jakub, Kiguba, Ronald, Kim, Peter K., Kluger, Yoram, Khokha, Vladimir, Koike, Kaoru, Kok, Kenneth Y. Y., Kong, Victory, Knox, Matthew C., Inaba, Kenji, Isik, Arda, Iskandar, Katia, Ivatury, Rao R., Labbate, Maurizio, Labricciosa, Francesco M., Laterre, Pierre-Françoi, Latifi, Rifat, Lee, Jae Gil, Lee, Young Ran, Leone, Marc, Leppaniemi, Ari, Li, Yousheng, Liang, Stephen Y., Loho, Tonny, Maegele, Marc, Malama, Sydney, Marei, Hany E., Martin-Loeches, Ignacio, Marwah, Sanjay, Massele, Amo, Mcfarlane, Michael, Melo, Renato Bessa, Negoi, Ionut, Nicolau, David P., Nord, Carl Erik, Ofori-Asenso, Richard, Omari, AbdelKarim H., Ordonez, Carlos A., Ouadii, Mouaqit, Pereira Júnior, Gerson Alve, Piazza, Diego, Pupelis, Guntar, Rawson, Timothy Mile, Rems, Miran, Rizoli, Sandro, Rocha, Claudio, Sakakhushev, Bori, Sanchez-Garcia, Miguel, Sato, Norio, Segovia Lohse, Helmut A., Sganga, Gabriele, Siribumrungwong, Boonying, Shelat, Vishal G., Soreide, Kjetil, Soto, Rodolfo, Talving, Peep, Tilsed, Jonathan V., Timsit, Jean-Francoi, Trueba, Gabriel, Trung, Ngo Tat, Ulrych, Jan, van Goor, Harry, Vereczkei, Andra, Vohra, Ravinder S., Wani, Imtiaz, Uhl, Waldemar, Xiao, Yonghong, Yuan, Kuo-Ching, Zachariah, Sanoop K., Zahar, Jean-Ralph, Zakrison, Tanya L., Corcione, Antonio, Melotti, Rita M., Viscoli, Claudio, Viale, Perluigi, UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - (SLuc) Service de soins intensifs, INSB-INSB-Centre National de la Recherche Scientifique (CNRS), University of Genoa (UNIGE), Sartelli, M, Weber, DG, Ruppe, E, Bassetti, M, Dorj, G, Kok, Kenneth Y.Y., and Viale, Pierluigi
Subjects: Anti-Infective Agent, 0301 basic medicine, INTENSIVE-CARE-UNIT, International Cooperation, Settore MED/18 - CHIRURGIA GENERALE, Drug Resistance, morbidity, Review, Drug resistance, Tigecycline, CLOSTRIDIUM-DIFFICILE INFECTION, VANCOMYCIN-RESISTANT ENTEROCOCCI, Microbial, SPECTRUM-BETA-LACTAMASE, 0302 clinical medicine, Anti-Infective Agents, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Medicine and Health Sciences, Agora, 030212 general & internal medicine, wb_330, computer.programming_language, Iais, biology, Microbial Sensitivity Test, Antimicrobials, Drug Resistance, Microbial, Antimicrobials, (AGORA), Prognosis, Antimicrobial, 3. Good health, CARBAPENEMASE-PRODUCING ENTEROBACTERIACEAE, antibiotic-resistance, Intra-abdominal infections (IAI), Surgery, Emergency Medicine, CLINICAL-PRACTICE GUIDELINES, 7c0bbdab, BLOOD-STREAM INFECTIONS, CRITICALLY-ILL PATIENTS, Human, medicine.drug, medicine.medical_specialty, Prognosi, 030106 microbiology, Microbial Sensitivity Tests, wa_110, qw_45, Emerging and Re-emerging Infectious Diseases, 03 medical and health sciences, wi_140, Antibiotic resistance, Intraabdominal Infection, medicine, Humans, intra-abdominal infections, GRAM-NEGATIVE BACTERIA, Intensive care medicine, Chirurgie, VENTILATOR-ASSOCIATED PNEUMONIA, business.industry, Médecine pathologie humaine, Intraabdominal Infections, biology.organism_classification, Review article, Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10], business, computer
Abstract: Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients. The cornerstones in the management of complicated IAIs are timely effective source control with appropriate antimicrobial therapy. Empiric antimicrobial therapy is important in the management of intra-abdominal infections and must be broad enough to cover all likely organisms because inappropriate initial antimicrobial therapy is associated with poor patient outcomes and the development of bacterial resistance. The overuse of antimicrobials is widely accepted as a major driver of some emerging infections (such as C. difficile), the selection of resistant pathogens in individual patients, and for the continued development of antimicrobial resistance globally. The growing emergence of multi-drug resistant organisms and the limited development of new agents available to counteract them have caused an impending crisis with alarming implications, especially with regards to Gram-negative bacteria. An international task force from 79 different countries has joined this project by sharing a document on the rational use of antimicrobials for patients with IAIs. The project has been termed AGORA (Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections). The authors hope that AGORA, involving many of the world's leading experts, can actively raise awareness in health workers and can improve prescribing behavior in treating IAIs., 0, SCOPUS: ar.j, info:eu-repo/semantics/published
Published: 2016
Full Text: View/download PDF

42. Erratum: Antimicrobials: A global alliance for optimizing their rational use in intra-abdominal infections (AGORA). [World J Emerg Surg. 11, (2016) (33)] DOI: 10.1186/s13017-016-0089-y

Author: Sartelli, M. Weber, D.G. Ruppé, E. Bassetti, M. Wright, B.J. Ansaloni, L. Catena, F. Coccolini, F. Abu-Zidan, F.M. Coimbra, R. Moore, E.E. Moore, F.A. Maier, R.V. De Waele, J.J. Kirkpatrick, A.W. Griffiths, E.A. Eckmann, C. Brink, A.J. Mazuski, J.E. May, A.K. Sawyer, R.G. Mertz, D. Montravers, P. Kumar, A. Roberts, J.A. Vincent, J.L. Watkins, R.R. Lowman, W. Spellberg, B. Abbott, I.J. Adesunkanmi, A.K. Al-Dahir, S. Al-Hasan, M.N. Agresta, F. Althani, A.A. Ansari, S. Ansumana, R. Augustin, G. Bala, M. Balogh, Z.J. Baraket, O. Bhangu, A. Beltrán, M.A. Bernhard, M. Biffl, W.L. Boermeester, M.A. Brecher, S.M. Cherry-Bukowiec, J.R. Buyne, O.R. Cainzos, M.A. Cairns, K.A. Camacho-Ortiz, A. Chandy, S.J. Che Jusoh, A. Chichom-Mefire, A. Colijn, C. Corcione, F. Cui, Y. Curcio, D. Delibegovic, S. Demetrashvili, Z. De Simone, B. Dhingra, S. Diaz, J.J. Di Carlo, I. Dillip, A. Di Saverio, S. Doyle, M.P. Dorj, G. Dogjani, A. Dupont, H. Eachempati, S.R. Enani, M.A. Egiev, V.N. Elmangory, M.M. Ferrada, P. Fitchett, J.R. Fraga, G.P. Guessennd, N. Giamarellou, H. Ghnnam, W. Gkiokas, G. Goldberg, S.R. Gomes, C.A. Gomi, H. Guzmán-Blanco, M. Haque, M. Hansen, S. Hecker, A. Heizmann, W.R. Herzog, T. Hodonou, A.M. Hong, S.K. Kafka-Ritsch, R. Kaplan, L.J. Kapoor, G. Karamarkovic, A. Kees, M.G. Kenig, J. Kiguba, R. Kim, P.K. Kluger, Y. Khokha, V. Koike, K. Kok, K.Y. Kong, V. Knox, M.C. Inaba, K. Isik, A. Iskandar, K. Ivatury, R.R. Labbate, M. Labricciosa, F.M. Laterre, P.F. Latifi, R. Lee, J.G. Lee, Y.R. Leone, M. Leppaniemi, A. Li, Y. Liang, S.Y. Loho, T. Maegele, M. Malama, S. Marei, H.E. Martin-Loeches, I. Marwah, S. Massele, A. McFarlane, M. Melo, R.B. Negoi, I. Nicolau, D.P. Nord, C.E. Ofori-Asenso, R. Omari, A.H. Ordonez, C.A. Ouadii, M. Pereira Júnior, G.A. Piazza, D. Pupelis, G. Rawson, T.M. Rems, M. Rizoli, S. Rocha, C. Sakakushev, B. Sanchez-Garcia, M. Sato, N. Segovia Lohse, H.A. Sganga, G. Siribumrungwong, B. Shelat, V.G. Soreide, K. Soto, R. Talving, P. Tilsed, J.V. Timsit, J.F. Trueba, G. Trung, N.T. Ulrych, J. van Goor, H. Vereczkei, A. Vohra, R.S. Wani, I. Uhl, W. Xiao, Y. Yuan, K.C. Zachariah, S.K. Zahar, J.R. Zakrison, T.L. Corcione, A. Melotti, R.M. Viscoli, C. Viale, P.
Subjects: lipids (amino acids, peptides, and proteins)
Abstract: The original article [1] contains an error whereby a co-author, Boris Sakakushev has their family name spelt incorrectly as 'Sakakhushev'. The authors would therefore like it known that the correct spelling of the family name is 'Sakakushev'. © The Author(s).
Published: 2017

43. Antimicrobials : a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)

Author: Sartelli, Massimo, Weber, Dieter G., Ruppe, Etienne, Bassetti, Matteo, Wright, Brian J., Ansaloni, Luca, Catena, Fausto, Coccolini, Federico, Abu-Zidan, Fikri M., Coimbra, Raul, Moore, Ernest E., Moore, Frederick A., Maier, Ronald V., De Waele, Jan J., Kirkpatrick, Andrew W., Griffiths, Ewen A., Eckmann, Christian, Brink, Adrian J., Mazuski, John E., May, Addison K., Sawyer, Rob G., Mertz, Dominik, Montravers, Philippe, Kumar, Anand, Roberts, Jason A., Vincent, Jean-Louis, Watkins, Richard R., Lowman, Warren, Spellberg, Brad, Abbott, Iain J., Adesunkanmi, Abdulrashid Kayode, Al-Dahir, Sara, Al-Hasan, Majdi N., Agresta, Ferdinando, Althani, Asma A., Ansari, Shamshul, Ansumana, Rashid, Augustin, Goran, Bala, Miklosh, Balogh, Zsolt J., Baraket, Oussama, Bhangu, Aneel, Beltran, Marcelo A., Bernhard, Michael, Biffl, Walter L., Boermeester, Marja A., Brecher, Stephen M., Cherry-Bukowiec, Jill R., Buyne, Otmar R., Cainzos, Miguel A., Cairns, Kelly A., Camacho-Ortiz, Adrian, Chandy, Sujith J., Jusoh, Asri Che, Chichom-Mefire, Alain, Colijn, Caroline, Corcione, Francesco, Cui, Yunfeng, Curcio, Daniel, Delibegovic, Samir, Demetrashvili, Zaza, De Simone, Belinda, Dhingra, Sameer, Diaz, Jose J., Di Carlo, Isidoro, Dillip, Angel, Di Saverio, Salomone, Doyle, Michael P., Dorj, Gereltuya, Dogjani, Agron, Dupont, Herve, Eachempati, Soumitra R., Enani, Mushira Abdulaziz, Egiev, Valery N., Elmangory, Mutasim M., Ferrada, Paula, Fitchett, Joseph R., Fraga, Gustavo P., Guessennd, Nathalie, Giamarellou, Helen, Ghnnam, Wagih, Gkiokas, George, Goldberg, Staphanie R., Gomes, Carlos Augusto, Gomi, Harumi, Guzman-Blanco, Manuel, Haque, Mainul, Hansen, Sonja, Hecker, Andreas, Heizmann, Wolfgang R., Herzog, Torsten, Hodonou, Adrien Montcho, Hong, Suk-Kyung, Kafka-Ritsch, Reinhold, Kaplan, Lewis J., Kapoor, Garima, Karamarkovic, Aleksandar, Kees, Martin G., Kenig, Jakub, Kiguba, Ronald, Kim, Peter K., Kluger, Yoram, Khokha, Vladimir, Koike, Kaoru, Kok, Kenneth Y. Y., Kong, Victory, Knox, Matthew C., Inaba, Kenji, Isik, Arda, Iskandar, Katia, Ivatury, Rao R., Labbate, Maurizio, Labricciosa, Francesco M., Laterre, Pierre-Francois, Latifi, Rifat, Lee, Jae Gil, Lee, Young Ran, Leone, Marc, Leppäniemi, Ari, Li, Yousheng, Liang, Stephen Y., Loho, Tonny, Maegele, Marc, Malama, Sydney, Marei, Hany E., Martin-Loeches, Ignacio, Marwah, Sanjay, Massele, Amos, McFarlane, Michael, Melo, Renato Bessa, Negoi, Ionut, Nicolau, David P., Nord, Carl Erik, Ofori-Asenso, Richard, Omari, AbdelKarim H., Ordonez, Carlos A., Ouadii, Mouaqit, Pereira Junior, Gerson Alves, Piazza, Diego, Pupelis, Guntars, Rawson, Timothy Miles, Rems, Miran, Rizoli, Sandro, Rocha, Claudio, Sakakhushev, Boris, Sanchez-Garcia, Miguel, Sato, Norio, Lohse, Helmut A. Segovia, Sganga, Gabriele, Siribumrungwong, Boonying, Shelat, Vishal G., Soreide, Kjetil, Soto, Rodolfo, Talving, Peep, Tilsed, Jonathan V., Timsit, Jean-Francois, Trueba, Gabriel, Trung, Ngo Tat, Ulrych, Jan, van Goor, Harry, Vereczkei, Andras, Vohra, Ravinder S., Wani, Imtiaz, Uhl, Waldemar, Xiao, Yonghong, Yuan, Kuo-Ching, Zachariah, Sanoop K., Zahar, Jean-Ralph, Zakrison, Tanya L., Corcione, Antonio, Melotti, Rita M., Viscoli, Claudio, Viale, Perluigi, II kirurgian klinikka, Department of Surgery, and Clinicum
Subjects: CARBAPENEMASE-PRODUCING ENTEROBACTERIACEAE, INTENSIVE-CARE-UNIT, SPECTRUM-BETA-LACTAMASE, VENTILATOR-ASSOCIATED PNEUMONIA, CLINICAL-PRACTICE GUIDELINES, GRAM-NEGATIVE BACTERIA, CLOSTRIDIUM-DIFFICILE INFECTION, BLOOD-STREAM INFECTIONS, 3126 Surgery, anesthesiology, intensive care, radiology, CRITICALLY-ILL PATIENTS, VANCOMYCIN-RESISTANT ENTEROCOCCI
Abstract: Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients. The cornerstones in the management of complicated IAIs are timely effective source control with appropriate antimicrobial therapy. Empiric antimicrobial therapy is important in the management of intra-abdominal infections and must be broad enough to cover all likely organisms because inappropriate initial antimicrobial therapy is associated with poor patient outcomes and the development of bacterial resistance. The overuse of antimicrobials is widely accepted as a major driver of some emerging infections (such as C. difficile), the selection of resistant pathogens in individual patients, and for the continued development of antimicrobial resistance globally. The growing emergence of multi-drug resistant organisms and the limited development of new agents available to counteract them have caused an impending crisis with alarming implications, especially with regards to Gram-negative bacteria. An international task force from 79 different countries has joined this project by sharing a document on the rational use of antimicrobials for patients with IAIs. The project has been termed AGORA (Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections). The authors hope that AGORA, involving many of the world's leading experts, can actively raise awareness in health workers and can improve prescribing behavior in treating IAIs.
Published: 2016

44. Antimicrobials: A global alliance for optimizing their rational use in intra-abdominal infections (AGORA)

Author: Sartelli, M, Weber, DG, Ruppé, E, Bassetti, M, Wright, BJ, Ansaloni, L, Catena, F, Coccolini, F, Abu-Zidan, FM, Coimbra, R, Moore, EE, Moore, FA, Maier, RV, De Waele, JJ, Kirkpatrick, AW, Griffiths, EA, Eckmann, C, Brink, AJ, Mazuski, JE, May, AK, Sawyer, RG, Mertz, D, Montravers, P, Kumar, A, Roberts, JA, Vincent, JL, Watkins, RR, Lowman, W, Spellberg, B, Abbott, IJ, Adesunkanmi, AK, Al-Dahir, S, Al-Hasan, MN, Agresta, F, Althani, AA, Ansari, S, Ansumana, R, Augustin, G, Bala, M, Balogh, ZJ, Baraket, O, Bhangu, A, Beltrán, MA, Bernhard, M, Biffl, WL, Boermeester, MA, Brecher, SM, Cherry-Bukowiec, JR, Buyne, OR, Cainzos, MA, Cairns, KA, Camacho-Ortiz, A, Chandy, SJ, Che Jusoh, A, Chichom-Mefire, A, Colijn, C, Corcione, F, Cui, Y, Curcio, D, Delibegovic, S, Demetrashvili, Z, De Simone, B, Dhingra, S, Diaz, JJ, Di Carlo, I, Dillip, A, Di Saverio, S, Doyle, MP, Dorj, G, Dogjani, A, Dupont, H, Eachempati, SR, Enani, MA, Egiev, VN, Elmangory, MM, Ferrada, P, Fitchett, JR, Fraga, GP, Guessennd, N, Giamarellou, H, Ghnnam, W, Gkiokas, G, Goldberg, SR, Gomes, CA, Gomi, H, Guzmán-Blanco, M, Haque, M, Hansen, S, Hecker, A, Heizmann, WR, Herzog, T, Hodonou, AM, Hong, SK, Kafka-Ritsch, R, Kaplan, LJ, Kapoor, G, Karamarkovic, A, Kees, MG, Kenig, J, and Kiguba, R
Subjects: Anti-Infective Agents, International Cooperation, Humans, Intraabdominal Infections, Surgery, Drug Resistance, Microbial, Microbial Sensitivity Tests, Prognosis
Abstract: © 2016 The Author(s). Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients. The cornerstones in the management of complicated IAIs are timely effective source control with appropriate antimicrobial therapy. Empiric antimicrobial therapy is important in the management of intra-abdominal infections and must be broad enough to cover all likely organisms because inappropriate initial antimicrobial therapy is associated with poor patient outcomes and the development of bacterial resistance. The overuse of antimicrobials is widely accepted as a major driver of some emerging infections (such as C. difficile), the selection of resistant pathogens in individual patients, and for the continued development of antimicrobial resistance globally. The growing emergence of multi-drug resistant organisms and the limited development of new agents available to counteract them have caused an impending crisis with alarming implications, especially with regards to Gram-negative bacteria. An international task force from 79 different countries has joined this project by sharing a document on the rational use of antimicrobials for patients with IAIs. The project has been termed AGORA (Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections). The authors hope that AGORA, involving many of the world's leading experts, can actively raise awareness in health workers and can improve prescribing behavior in treating IAIs.
Published: 2016

45. Syntheticvsbiologic mesh for the repair and prevention of parastomal hernia

Author: Knaapen, Loes, primary, Buyne, Otmar, additional, Goor, Harry van, additional, and Slater, Nicholas J, additional
Published: 2017
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46. Erratum to: Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)

Author: Sartelli, M., primary, Weber, D. G., additional, Ruppé, E., additional, Bassetti, M., additional, Wright, B. J., additional, Ansaloni, L., additional, Catena, F., additional, Coccolini, F., additional, Abu-Zidan, F. M., additional, Coimbra, R., additional, Moore, E. E., additional, Moore, F. A., additional, Maier, R. V., additional, De Waele, J. J., additional, Kirkpatrick, A. W., additional, Griffiths, E. A., additional, Eckmann, C., additional, Brink, A. J., additional, Mazuski, J. E., additional, May, A. K., additional, Sawyer, R. G., additional, Mertz, D., additional, Montravers, P., additional, Kumar, A., additional, Roberts, J. A., additional, Vincent, J. L., additional, Watkins, R. R., additional, Lowman, W., additional, Spellberg, B., additional, Abbott, I. J., additional, Adesunkanmi, A. K., additional, Al-Dahir, S., additional, Al-Hasan, M. N., additional, Agresta, F., additional, Althani, A. A., additional, Ansari, S., additional, Ansumana, R., additional, Augustin, G., additional, Bala, M., additional, Balogh, Z. J., additional, Baraket, O., additional, Bhangu, A., additional, Beltrán, M. A., additional, Bernhard, M., additional, Biffl, W. L., additional, Boermeester, M. A., additional, Brecher, S. M., additional, Cherry-Bukowiec, J. R., additional, Buyne, O. R., additional, Cainzos, M. A., additional, Cairns, K. A, additional, Camacho-Ortiz, A., additional, Chandy, S. J., additional, Che Jusoh, A., additional, Chichom-Mefire, A., additional, Colijn, C., additional, Corcione, F., additional, Cui, Y., additional, Curcio, D., additional, Delibegovic, S., additional, Demetrashvili, Z., additional, De Simone, B., additional, Dhingra, S., additional, Diaz, J. J., additional, Di Carlo, I., additional, Dillip, A., additional, Di Saverio, S., additional, Doyle, M. P., additional, Dorj, G., additional, Dogjani, A., additional, Dupont, H., additional, Eachempati, S. R., additional, Enani, M. A., additional, Egiev, V. N., additional, Elmangory, M. M., additional, Ferrada, P., additional, Fitchett, J. R., additional, Fraga, G. P., additional, Guessennd, N., additional, Giamarellou, H., additional, Ghnnam, W., additional, Gkiokas, G., additional, Goldberg, S. R., additional, Gomes, C. A., additional, Gomi, H., additional, Guzmán-Blanco, M., additional, Haque, M., additional, Hansen, S., additional, Hecker, A., additional, Heizmann, W. R., additional, Herzog, T., additional, Hodonou, A. M., additional, Hong, S. K., additional, Kafka-Ritsch, R., additional, Kaplan, L. J., additional, Kapoor, G., additional, Karamarkovic, A., additional, Kees, M. G., additional, Kenig, J., additional, Kiguba, R., additional, Kim, P. K., additional, Kluger, Y., additional, Khokha, V., additional, Koike, K., additional, Kok, K. Y., additional, Kong, V., additional, Knox, M. C., additional, Inaba, K., additional, Isik, A., additional, Iskandar, K., additional, Ivatury, R. R., additional, Labbate, M., additional, Labricciosa, F. M., additional, Laterre, P. F., additional, Latifi, R., additional, Lee, J. G., additional, Lee, Y. R., additional, Leone, M., additional, Leppaniemi, A., additional, Li, Y., additional, Liang, S. Y., additional, Loho, T., additional, Maegele, M., additional, Malama, S., additional, Marei, H. E., additional, Martin-Loeches, I., additional, Marwah, S., additional, Massele, A., additional, McFarlane, M., additional, Melo, R. B., additional, Negoi, I., additional, Nicolau, D. P., additional, Nord, C. E., additional, Ofori-Asenso, R., additional, Omari, A. H., additional, Ordonez, C. A., additional, Ouadii, M., additional, Pereira Júnior, G. A., additional, Piazza, D., additional, Pupelis, G., additional, Rawson, T. M., additional, Rems, M., additional, Rizoli, S., additional, Rocha, C., additional, Sakakushev, B., additional, Sanchez-Garcia, M., additional, Sato, N., additional, Segovia Lohse, H. A., additional, Sganga, G., additional, Siribumrungwong, B., additional, Shelat, V. G., additional, Soreide, K., additional, Soto, R., additional, Talving, P., additional, Tilsed, J. V., additional, Timsit, J. F., additional, Trueba, G., additional, Trung, N. T., additional, Ulrych, J., additional, van Goor, H., additional, Vereczkei, A., additional, Vohra, R. S., additional, Wani, I., additional, Uhl, W., additional, Xiao, Y., additional, Yuan, K. C., additional, Zachariah, S. K., additional, Zahar, J. R., additional, Zakrison, T. L., additional, Corcione, A., additional, Melotti, R. M., additional, Viscoli, C., additional, and Viale, P., additional
Published: 2017
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47. Synthetic vs biologic mesh for the repair and prevention of parastomal hernia

Author: Knaapen, L., Buyne, O.R., Goor, H. van, Slater, N.J., Knaapen, L., Buyne, O.R., Goor, H. van, and Slater, N.J.
Abstract: Contains fulltext : 181803.pdf (publisher's version ) (Open Access)
Published: 2017

48. Large Contaminated Ventral Hernia Repair Using Component Separation Technique with Synthetic Mesh

Author: Dietmar J.O. Ulrich, Robert P. Bleichrodt, Marleen J. A. Biemans, O.R. Buyne, Nicholas J. Slater, L. Knaapen, Harry van Goor, and W. J. V. Bökkerink
Subjects: Adult, Male, medicine.medical_specialty, New materials, Young Adult, Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], medicine, Humans, Surgical Wound Infection, Hernia, Herniorrhaphy, Aged, Retrospective Studies, Ventral hernia repair, business.industry, Surgical wound, Retrospective cohort study, Equipment Design, Middle Aged, Surgical Mesh, medicine.disease, Component separation, Hernia, Ventral, Surgery, Women's cancers Radboud Institute for Health Sciences [Radboudumc 17], Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10], Surgical mesh, Reconstructive and regenerative medicine Radboud Institute for Molecular Life Sciences [Radboudumc 10], Ventral hernia, Female, business
Abstract: Item does not contain fulltext BACKGROUND: Large ventral hernia repair represents a major reconstructive surgical challenge, especially under contaminated conditions. Synthetic mesh is usually avoided in these circumstances because of fear of mesh infection, although evidence is outdated and does not regard new materials and techniques. The authors evaluated the safety of synthetic mesh in large contaminated ventral hernia repair. METHODS: All large ventral hernias repaired with the components separation technique and polypropylene mesh were included in analysis. Primary outcomes were wound and medical complications, with a focus on surgical-site infection and mesh removal. For risk analysis, patients were stratified by surgical wound class, Ventral Hernia Working Group grade, and modified Ventral Hernia Working Group grade. RESULTS: One hundred thirty-seven patients were included, with a mean age of 58.6 years, mean body mass index of 26.6 cm, and mean defect size of 235.6 cm. Surgical-site infection and total wound complication rates were 16.1 and 48.9 percent, respectively. The surgical wound class distribution of surgical-site infections was as follows: clean, five of 56 (9.1 percent); clean-contaminated, five of 34 (14.7 percent); contaminated, three of 19 (15.8 percent); and dirty/infected, nine of 28 (32.1 percent). Seven meshes (5.1 percent) needed removal, two after clean repairs, three after clean-contaminated repairs, and two after dirty/infected repairs. Surgical wound class (OR, 1.77; 95 percent CI, 1.20 to 2.61) and Ventral Hernia Working Group grade (OR, 2.31; 95 percent CI, 1.24 to 4.28) were predictors of surgical-site infection. CONCLUSION: Rate of surgical-site infection after large contaminated ventral hernia repair with synthetic mesh is considerable but with a low mesh removal rate. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.
Published: 2015
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49. Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)

Author: Sartelli, M., Weber, D.G., Ruppe, E., Bassetti, M., Wright, B.J., Ansaloni, L., Catena, F., Coccolini, F., Abu-Zidan, F.M., Coimbra, R., Moore, E.E., Moore, F.A., Maier, R.V., Waele, J.J. De, Kirkpatrick, A.W., Griffiths, E.A., Eckmann, C., Brink, A.J., Mazuski, J.E., May, A.K., Sawyer, R.G., Mertz, D., Montravers, P., Kumar, A., Roberts, J.A., Vincent, J.L., Watkins, R.R., Lowman, W., Spellberg, B., Abbott, I.J., Adesunkanmi, A.K., Al-Dahir, S., Al-Hasan, M.N., Agresta, F., Althani, A.A., Ansari, S., Ansumana, R., Augustin, G., Bala, M., Balogh, Z.J., Baraket, O., Bhangu, A., Beltran, M.A., Bernhard, M., Biffl, W.L., Boermeester, M.A., Brecher, S.M., Cherry-Bukowiec, J.R., Buyne, O.R., Cainzos, M.A., Cairns, K.A., Camacho-Ortiz, A., Chandy, S.J., Jusoh, A. Che, Chichom-Mefire, A., Colijn, C., Corcione, F., Cui, Y., Curcio, D., Delibegovic, S., Demetrashvili, Z., Simone, B. De, Dhingra, S., Diaz, J.J., Carlo, I. Di, Dillip, A., Saverio, S. Di, Doyle, M.P., Dorj, G., Dogjani, A., Dupont, H., Eachempati, S.R., Enani, M.A., Egiev, V.N., Elmangory, M.M., Ferrada, P., Fitchett, J.R., Fraga, G.P., Guessennd, N., Giamarellou, H., Ghnnam, W., Gkiokas, G., Goldberg, S.R., Gomes, C.A., Gomi, H., Guzman-Blanco, M., Haque, M., Hansen, S., Hecker, A., Heizmann, W.R., Herzog, T., Hodonou, A.M., Hong, S.K., Kafka-Ritsch, R., Kaplan, L.J., Kapoor, G., Karamarkovic, A., Kees, M.G., Kenig, J., Kiguba, R., et al., Sartelli, M., Weber, D.G., Ruppe, E., Bassetti, M., Wright, B.J., Ansaloni, L., Catena, F., Coccolini, F., Abu-Zidan, F.M., Coimbra, R., Moore, E.E., Moore, F.A., Maier, R.V., Waele, J.J. De, Kirkpatrick, A.W., Griffiths, E.A., Eckmann, C., Brink, A.J., Mazuski, J.E., May, A.K., Sawyer, R.G., Mertz, D., Montravers, P., Kumar, A., Roberts, J.A., Vincent, J.L., Watkins, R.R., Lowman, W., Spellberg, B., Abbott, I.J., Adesunkanmi, A.K., Al-Dahir, S., Al-Hasan, M.N., Agresta, F., Althani, A.A., Ansari, S., Ansumana, R., Augustin, G., Bala, M., Balogh, Z.J., Baraket, O., Bhangu, A., Beltran, M.A., Bernhard, M., Biffl, W.L., Boermeester, M.A., Brecher, S.M., Cherry-Bukowiec, J.R., Buyne, O.R., Cainzos, M.A., Cairns, K.A., Camacho-Ortiz, A., Chandy, S.J., Jusoh, A. Che, Chichom-Mefire, A., Colijn, C., Corcione, F., Cui, Y., Curcio, D., Delibegovic, S., Demetrashvili, Z., Simone, B. De, Dhingra, S., Diaz, J.J., Carlo, I. Di, Dillip, A., Saverio, S. Di, Doyle, M.P., Dorj, G., Dogjani, A., Dupont, H., Eachempati, S.R., Enani, M.A., Egiev, V.N., Elmangory, M.M., Ferrada, P., Fitchett, J.R., Fraga, G.P., Guessennd, N., Giamarellou, H., Ghnnam, W., Gkiokas, G., Goldberg, S.R., Gomes, C.A., Gomi, H., Guzman-Blanco, M., Haque, M., Hansen, S., Hecker, A., Heizmann, W.R., Herzog, T., Hodonou, A.M., Hong, S.K., Kafka-Ritsch, R., Kaplan, L.J., Kapoor, G., Karamarkovic, A., Kees, M.G., Kenig, J., Kiguba, R., and et al.
Abstract: Contains fulltext : 168575.pdf (publisher's version ) (Open Access), Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients. The cornerstones in the management of complicated IAIs are timely effective source control with appropriate antimicrobial therapy. Empiric antimicrobial therapy is important in the management of intra-abdominal infections and must be broad enough to cover all likely organisms because inappropriate initial antimicrobial therapy is associated with poor patient outcomes and the development of bacterial resistance. The overuse of antimicrobials is widely accepted as a major driver of some emerging infections (such as C. difficile), the selection of resistant pathogens in individual patients, and for the continued development of antimicrobial resistance globally. The growing emergence of multi-drug resistant organisms and the limited development of new agents available to counteract them have caused an impending crisis with alarming implications, especially with regards to Gram-negative bacteria. An international task force from 79 different countries has joined this project by sharing a document on the rational use of antimicrobials for patients with IAIs. The project has been termed AGORA (Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections). The authors hope that AGORA, involving many of the world's leading experts, can actively raise awareness in health workers and can improve prescribing behavior in treating IAIs.
Published: 2016

50. Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA).

Author: UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - (SLuc) Service de soins intensifs, Sartelli, Massimo, Weber, Dieter G, Ruppé, Etienne, Bassetti, Matteo, Wright, Brian J, Ansaloni, Luca, Catena, Fausto, Coccolini, Federico, Abu-Zidan, Fikri M, Coimbra, Raul, Moore, Ernest E, Moore, Frederick A, Maier, Ronald V, De Waele, Jan J, Kirkpatrick, Andrew W, Griffiths, Ewen A, Eckmann, Christian, Brink, Adrian J, Mazuski, John E, May, Addison K, Sawyer, Rob G, Mertz, Dominik, Montravers, Philippe, Kumar, Anand, Roberts, Jason A, Vincent, Jean-Louis, Watkins, Richard R, Lowman, Warren, Spellberg, Brad, Abbott, Iain J, Adesunkanmi, Abdulrashid Kayode, Al-Dahir, Sara, Al-Hasan, Majdi N, Agresta, Ferdinando, Althani, Asma A, Ansari, Shamshul, Ansumana, Rashid, Augustin, Goran, Bala, Miklosh, Balogh, Zsolt J, Baraket, Oussama, Bhangu, Aneel, Beltrán, Marcelo A, Bernhard, Michael, Biffl, Walter L, Boermeester, Marja A, Brecher, Stephen M, Cherry-Bukowiec, Jill R, Buyne, Otmar R, Cainzos, Miguel A, Cairns, Kelly A, Camacho-Ortiz, Adrian, Chandy, Sujith J, Che Jusoh, Asri, Chichom-Mefire, Alain, Colijn, Caroline, Corcione, Francesco, Cui, Yunfeng, Curcio, Daniel, Delibegovic, Samir, Demetrashvili, Zaza, De Simone, Belinda, Dhingra, Sameer, Diaz, José J, Di Carlo, Isidoro, Dillip, Angel, Di Saverio, Salomone, Doyle, Michael P, Dorj, Gereltuya, Dogjani, Agron, Dupont, Hervé, Eachempati, Soumitra R, Enani, Mushira Abdulaziz, Egiev, Valery N, Elmangory, Mutasim M, Ferrada, Paula, Fitchett, Joseph R, Fraga, Gustavo P, Guessennd, Nathalie, Giamarellou, Helen, Ghnnam, Wagih, Gkiokas, George, Goldberg, Staphanie R, Gomes, Carlos Augusto, Gomi, Harumi, Guzmán-Blanco, Manuel, Haque, Mainul, Hansen, Sonja, Hecker, Andreas, Heizmann, Wolfgang R, Herzog, Torsten, Hodonou, Adrien Montcho, Hong, Suk-Kyung, Kafka-Ritsch, Reinhold, Kaplan, Lewis J, Kapoor, Garima, Karamarkovic, Aleksandar, Kees, Martin G, Kenig, Jakub, Kiguba, Ronald, Kim, Peter K, Kluger, Yoram, Khokha, Vladimir, Koike, Kaoru, Kok, Kenneth Y Y, Kong, Victory, Knox, Matthew C, Inaba, Kenji, Isik, Arda, Iskandar, Katia, Ivatury, Rao R, Labbate, Maurizio, Labricciosa, Francesco M, Laterre, Pierre-François, Latifi, Rifat, Lee, Jae Gil, Lee, Young Ran, Leone, Marc, Leppaniemi, Ari, Li, Yousheng, Liang, Stephen Y, Loho, Tonny, Maegele, Marc, Malama, Sydney, Marei, Hany E, Martin-Loeches, Ignacio, Marwah, Sanjay, Massele, Amos, McFarlane, Michael, Melo, Renato Bessa, Negoi, Ionut, Nicolau, David P, Nord, Carl Erik, Ofori-Asenso, Richard, Omari, AbdelKarim H, Ordonez, Carlos A, Ouadii, Mouaqit, Pereira Júnior, Gerson Alves, Piazza, Diego, Pupelis, Guntars, Rawson, Timothy Miles, Rems, Miran, Rizoli, Sandro, Rocha, Claudio, Sakakhushev, Boris, Sanchez-Garcia, Miguel, Sato, Norio, Segovia Lohse, Helmut A, Sganga, Gabriele, Siribumrungwong, Boonying, Shelat, Vishal G, Soreide, Kjetil, Soto, Rodolfo, Talving, Peep, Tilsed, Jonathan V, Timsit, Jean-Francois, Trueba, Gabriel, Trung, Ngo Tat, Ulrych, Jan, van Goor, Harry, Vereczkei, Andras, Vohra, Ravinder S, Wani, Imtiaz, Uhl, Waldemar, Xiao, Yonghong, Yuan, Kuo-Ching, Zachariah, Sanoop K, Zahar, Jean-Ralph, Zakrison, Tanya L, Corcione, Antonio, Melotti, Rita M, Viscoli, Claudio, Viale, Perluigi, UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - (SLuc) Service de soins intensifs, Sartelli, Massimo, Weber, Dieter G, Ruppé, Etienne, Bassetti, Matteo, Wright, Brian J, Ansaloni, Luca, Catena, Fausto, Coccolini, Federico, Abu-Zidan, Fikri M, Coimbra, Raul, Moore, Ernest E, Moore, Frederick A, Maier, Ronald V, De Waele, Jan J, Kirkpatrick, Andrew W, Griffiths, Ewen A, Eckmann, Christian, Brink, Adrian J, Mazuski, John E, May, Addison K, Sawyer, Rob G, Mertz, Dominik, Montravers, Philippe, Kumar, Anand, Roberts, Jason A, Vincent, Jean-Louis, Watkins, Richard R, Lowman, Warren, Spellberg, Brad, Abbott, Iain J, Adesunkanmi, Abdulrashid Kayode, Al-Dahir, Sara, Al-Hasan, Majdi N, Agresta, Ferdinando, Althani, Asma A, Ansari, Shamshul, Ansumana, Rashid, Augustin, Goran, Bala, Miklosh, Balogh, Zsolt J, Baraket, Oussama, Bhangu, Aneel, Beltrán, Marcelo A, Bernhard, Michael, Biffl, Walter L, Boermeester, Marja A, Brecher, Stephen M, Cherry-Bukowiec, Jill R, Buyne, Otmar R, Cainzos, Miguel A, Cairns, Kelly A, Camacho-Ortiz, Adrian, Chandy, Sujith J, Che Jusoh, Asri, Chichom-Mefire, Alain, Colijn, Caroline, Corcione, Francesco, Cui, Yunfeng, Curcio, Daniel, Delibegovic, Samir, Demetrashvili, Zaza, De Simone, Belinda, Dhingra, Sameer, Diaz, José J, Di Carlo, Isidoro, Dillip, Angel, Di Saverio, Salomone, Doyle, Michael P, Dorj, Gereltuya, Dogjani, Agron, Dupont, Hervé, Eachempati, Soumitra R, Enani, Mushira Abdulaziz, Egiev, Valery N, Elmangory, Mutasim M, Ferrada, Paula, Fitchett, Joseph R, Fraga, Gustavo P, Guessennd, Nathalie, Giamarellou, Helen, Ghnnam, Wagih, Gkiokas, George, Goldberg, Staphanie R, Gomes, Carlos Augusto, Gomi, Harumi, Guzmán-Blanco, Manuel, Haque, Mainul, Hansen, Sonja, Hecker, Andreas, Heizmann, Wolfgang R, Herzog, Torsten, Hodonou, Adrien Montcho, Hong, Suk-Kyung, Kafka-Ritsch, Reinhold, Kaplan, Lewis J, Kapoor, Garima, Karamarkovic, Aleksandar, Kees, Martin G, Kenig, Jakub, Kiguba, Ronald, Kim, Peter K, Kluger, Yoram, Khokha, Vladimir, Koike, Kaoru, Kok, Kenneth Y Y, Kong, Victory, Knox, Matthew C, Inaba, Kenji, Isik, Arda, Iskandar, Katia, Ivatury, Rao R, Labbate, Maurizio, Labricciosa, Francesco M, Laterre, Pierre-François, Latifi, Rifat, Lee, Jae Gil, Lee, Young Ran, Leone, Marc, Leppaniemi, Ari, Li, Yousheng, Liang, Stephen Y, Loho, Tonny, Maegele, Marc, Malama, Sydney, Marei, Hany E, Martin-Loeches, Ignacio, Marwah, Sanjay, Massele, Amos, McFarlane, Michael, Melo, Renato Bessa, Negoi, Ionut, Nicolau, David P, Nord, Carl Erik, Ofori-Asenso, Richard, Omari, AbdelKarim H, Ordonez, Carlos A, Ouadii, Mouaqit, Pereira Júnior, Gerson Alves, Piazza, Diego, Pupelis, Guntars, Rawson, Timothy Miles, Rems, Miran, Rizoli, Sandro, Rocha, Claudio, Sakakhushev, Boris, Sanchez-Garcia, Miguel, Sato, Norio, Segovia Lohse, Helmut A, Sganga, Gabriele, Siribumrungwong, Boonying, Shelat, Vishal G, Soreide, Kjetil, Soto, Rodolfo, Talving, Peep, Tilsed, Jonathan V, Timsit, Jean-Francois, Trueba, Gabriel, Trung, Ngo Tat, Ulrych, Jan, van Goor, Harry, Vereczkei, Andras, Vohra, Ravinder S, Wani, Imtiaz, Uhl, Waldemar, Xiao, Yonghong, Yuan, Kuo-Ching, Zachariah, Sanoop K, Zahar, Jean-Ralph, Zakrison, Tanya L, Corcione, Antonio, Melotti, Rita M, Viscoli, Claudio, and Viale, Perluigi
Abstract: Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients. The cornerstones in the management of complicated IAIs are timely effective source control with appropriate antimicrobial therapy. Empiric antimicrobial therapy is important in the management of intra-abdominal infections and must be broad enough to cover all likely organisms because inappropriate initial antimicrobial therapy is associated with poor patient outcomes and the development of bacterial resistance. The overuse of antimicrobials is widely accepted as a major driver of some emerging infections (such as C. difficile), the selection of resistant pathogens in individual patients, and for the continued development of antimicrobial resistance globally. The growing emergence of multi-drug resistant organisms and the limited development of new agents available to counteract them have caused an impending crisis with alarming implications, especially with regards to Gram-negative bacteria. An international task force from 79 different countries has joined this project by sharing a document on the rational use of antimicrobials for patients with IAIs. The project has been termed AGORA (Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections). The authors hope that AGORA, involving many of the world's leading experts, can actively raise awareness in health workers and can improve prescribing behavior in treating IAIs.
Published: 2016

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