100 results on '"Álvarez Rodríguez J"'
Search Results
2. Ureteral replacement with robotic leal interposition
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Carvajal Buitrago, D.F., primary, Martos Calvo, R., additional, López Martínez, J.M., additional, Rodríguez Villamil, N.J., additional, Pellegrinelli, F., additional, Palazzetti, A., additional, Esper Rueda, J.A., additional, Álvarez Rodríguez, J., additional, Salinas Duffo, D., additional, and Pena González, J.A., additional
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- 2023
- Full Text
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3. Plasmapheresis in the intensive care units of the community of Madrid
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Alonso-Ovies, Á., primary and Álvarez Rodríguez, J., additional
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- 2022
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- View/download PDF
4. Plasmaféresis en las UCI de la Comunidad de Madrid
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Alonso-Ovies, Á., primary and Álvarez Rodríguez, J., additional
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- 2022
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5. O139 Carob pulp and high levels of Vitamin E do not affect performance trait and metabolic profile in fattening lambs
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Bottegal, D.N., primary, Álvarez-Rodríguez, J., additional, Latorre, M.A., additional, Espinal, J., additional, Verdú, M., additional, and Lobón, S., additional
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- 2022
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6. Interpretable clinical time-series modeling with intelligent feature selection for early prediction of antimicrobial multidrug resistance
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Universidade de Santiago de Compostela. Centro de Investigación en Tecnoloxías da Información, Martínez-Aguero, Sergio, Soguero-Ruiz, Cristina, Mora-Jiménez, Inmaculada, Álvarez-Rodríguez, J., Alonso Moral, Jose María, Marques, Antonio G., Universidade de Santiago de Compostela. Centro de Investigación en Tecnoloxías da Información, Martínez-Aguero, Sergio, Soguero-Ruiz, Cristina, Mora-Jiménez, Inmaculada, Álvarez-Rodríguez, J., Alonso Moral, Jose María, and Marques, Antonio G.
- Abstract
Electronic health records provide rich, heterogeneous data about the evolution of the patients’ health status. However, such data need to be processed carefully, with the aim of extracting meaningful information for clinical decision support. In this paper, we leverage interpretable (deep) learning and signal processing tools to deal with multivariate time-series data collected from the Intensive Care Unit (ICU) of the University Hospital of Fuenlabrada (Madrid, Spain). The presence of antimicrobial multidrug-resistant (AMR) bacteria is one of the greatest threats to the health system in general and to the ICUs in particular due to the critical health status of the patients therein. Thus, early identification of bacteria at the ICU and early prediction of their antibiotic resistance are key for the patients’ prognosis. While intelligent data-based processing and learning schemes can contribute to this early prediction, their acceptance and deployment in the ICUs require the automatic schemes to be not only accurate but also understandable by clinicians. Accordingly, we have designed trustworthy intelligent models for the early prediction of AMR based on the combination of meaningful feature selection with interpretable recurrent neural networks. These models were created using irregularly sampled clinical measurements, both considering the health status of the patient and the global ICU environment. We explored several strategies to cope with strongly imbalance data, since only a few ICU patients are infected by AMR bacteria. It is worth noting that our approach exhibits a good balance between performance and interpretability, especially when considering the difficulty of the classification task at hand. A multitude of factors are involved in the emergence of AMR (several of them not fully understood), and the records only contain a subset of them. In addition, the limited number of patients, the imbalance between classes, and the irregularity of the data render the
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- 2022
7. Nutritional strategies to cope with reduced litter weight gain and total tract digestibility in lactating sows
- Author
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Álvarez‐Rodríguez, J., Mir, L., Seradj, A. R., Morazán, H., Balcells, J., and Babot, D.
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- 2017
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8. Actitud de los consumidores españoles e italianos frente a jamones curados de cerdos inmunocastrados
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Pérez-Ciria, L., Álvarez-Rodríguez, J., Miana-Mena, F. J., Gallo, L., Schiavon, S., Ripoll, G., Blanco, M., Sanz, M. A., and Latorre, M. A.
- Subjects
Pig, ham, immunocastration, consumers ,Pig ,immunocastration ,Jamón ,Comportamiento del consumidor ,Cerdo castrado ,ham ,consumers - Abstract
Este trabajo ha sido financiado por el Fondo de Inversiones de Teruel (Proyecto TERUEL DRY-CURED HAM) y por el Ministerio de Economía y Competitividad del Gobierno de España (Proyecto AGL2016-78532-R). Published
- Published
- 2021
9. VE27 - Ureteral replacement with robotic leal interposition
- Author
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Carvajal Buitrago, D.F., Martos Calvo, R., López Martínez, J.M., Rodríguez Villamil, N.J., Pellegrinelli, F., Palazzetti, A., Esper Rueda, J.A., Álvarez Rodríguez, J., Salinas Duffo, D., and Pena González, J.A.
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- 2023
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10. Estrategias de alimentación, evaluación del impacto ambiental y valoración económica de dietas de porcino ecológico
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Argemí Armengol, Inma, Villalba Mata, Daniel, Tor, M., Álvarez-Rodríguez, J, Argemí Armengol, Inma, Villalba Mata, Daniel, Tor, M., and Álvarez-Rodríguez, J
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The main dietary challenge for organic swine feeding is ensuring that feed fulfils the nutrient requirements, in particular to protein and amino acid profile, after the expiration that allow producers to include up to 5% non-organic feed within their rations, which is expected to 2020. Thus, this work was designed to propose an organic feeding strategy and to analyse the nutritional, economic and environmental viability of locally produced feedstuff use. A representative sample of organic feed ingredients were selected, according to EC No 834/2007 and No 889/2008, in feed mills and producers from Catalonia and nearby area: cereals (n=22), cereal by-products (n=4) and protein concentrate (n=25). Diets were formulated for the different physiological phases, adjusted to the Spanish (FEDNA, conventional) and French (ITAB, organic) nutritional recommendations. Diets were formulated without soybean expeller or full-fat soybean when using French standards, using instead other protein sources adapted to the Mediterranean climate (Narbonne vetch, beans, peas, and fenugreek) and winter cereals (rye, wheat, barley and triticale). The assessment of environmental impacts (phosphorus demand, non-renewable energy, eutrophication, acidification, climate change and land occupation) of the diets (per unit of produced feed), through life-cycle analysis by means of the database ECOALIM (2016), was higher in piglets and lower in pregnant sows, and much higher when formulating according to FEDNA vs. ITAB standards. In the economic valuation of the diets (purchase or self-production), a business model that integrates agriculture and livestock farming would be more profitable., El principal desafío en alimentación para porcino ecológico es garantizar que los alimentos de la dieta cumplan los requerimientos nutricionales, en particular en proteína y perfil de aminoácidos, al finalizar la moratoria de uso de hasta un 5% de alimentos no ecológicos en las raciones, prevista para 2020. Así, este trabajo se planteó para proponer una estrategia de alimentación y analizar la viabilidad nutricional, económica y ambiental de formular raciones con alimentos alternativos, producidos localmente. Se seleccionó una muestra representativa de productos de cultivos ecológicos, de acuerdo al Reglamento (CE) 834/2007 y 889/2008, de fábricas de piensos y productores de Cataluña y zona próxima: cereales (n=22), subproductos de cereales (n=4) y concentrados de proteína vegetal (n=25). Las dietas se formularon para las diferentes fases fisiológicas, ajustadas a las recomendaciones nutricionales españolas (FEDNA, convencional) y francesas (ITAB, ecológicas). Se formularon dietas prescindiendo de la soja (torta de presión y soja integral) según recomendaciones nutricionales francesas y utilizando fuentes proteicas adaptadas al clima mediterráneo (alverjón, habas, guisantes y alholva) y cereales de invierno (centeno, trigo, cebada y triticale). Los impactos ambientales de las dietas (por unidad de pienso compuesto producido) en cuanto a demanda de fósforo, uso de energía no renovable, eutrofización, acidificación, cambio climático y ocupación de tierra, evaluados mediante el análisis de ciclo de vida de la base de datos francesa ECOALIM (2016), resultan mayores en lechones y menores en cerdas gestantes, y notablemente superiores si se formula según FEDNA vs. ITAB. En la valoración económica de las dietas (compra frente a autoproducción), resultaría más rentable un modelo de negocio con integración agropecuaria.
- Published
- 2020
11. Incorporación de la conexión río acuífero y del flujo subterráneo con r.gwflow en el modelo hidrológico de Témez
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García-Bravo, N, primary, Álvarez-Rodríguez, J, additional, and Potenciano de Las Heras, a, additional
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- 2021
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12. Plasmapheresis in the intensive care units of the community of Madrid
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Alonso-Ovies, Á. and Álvarez Rodríguez, J.
- Published
- 2023
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13. ¿Afectan los taninos condensados de la dieta a los resultados productivos, la composición de ácidos grasos y el color de la carne de cordero?
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Álvarez-Rodríguez, J., primary, Villalba, D., additional, Molina, E., additional, Serrano-Pérez, B., additional, Bertolín, J.R., additional, and Joy, M., additional
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- 2020
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14. Estrategias de alimentación, evaluación del impacto ambiental y valoración económica de dietas de porcino ecológico
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Argemí-Armengol, I., primary, Villalba, D., additional, Tor, M., additional, and Álvarez-Rodríguez, J., additional
- Published
- 2020
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15. Development of a hybrid model to interpolate monthly precipitation maps incorporating the orographic influence
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Universitat Politècnica de València. Departamento de Ingeniería Hidráulica y Medio Ambiente - Departament d'Enginyeria Hidràulica i Medi Ambient, Ministerio de Economía y Competitividad, Álvarez-Rodríguez, J., Llasat, M.C., Estrela Monreal, Teodoro, Universitat Politècnica de València. Departamento de Ingeniería Hidráulica y Medio Ambiente - Departament d'Enginyeria Hidràulica i Medi Ambient, Ministerio de Economía y Competitividad, Álvarez-Rodríguez, J., Llasat, M.C., and Estrela Monreal, Teodoro
- Abstract
[EN] This paper proposes an interpolation model for monthly rainfall in large areas of complex orography. It has been implemented in the Iberian Peninsula (continental territories of Spain and Portugal), Balearic and Canary Islands covering a territory of almost 600.000km(2). To do this a data set that comprises a total number of 11,822 monthly precipitation series has been created (11,042 provided by the Spanish Meteorological Agency and 780 provided by the National Water Resources Information System of the Portuguese Water Institute). The data set covers the period from October 1940 until September 2005. The interpolation model has been based on the assumption of two different components on monthly precipitation. The first component reflects local and seasonal characteristics and 24 different mean monthly precipitation maps (12) and SDs maps (12) compose it. It considers the varying influence of physiographic variables such as altitude and orientation. The second precipitation component reflects the synoptic pattern that dominated each month of the series and it is composed by series of anomalies of monthly precipitation (780). Anomalies have been interpolated by means of ordinary kriging once local spatial continuity was assumed. Gridded maps of each variable have been developed at 200m resolution following a hybrid methodology that implements two different interpolation techniques. The first technique applies a regression analysis to derive maps depending on altitude and orientation; the second one is a weighting technique to consider the non-linearity of the precipitation/altitude dependence. Cross validation has been applied to estimate the goodness of both techniques. Results show an average annual precipitation of 655mm/year. Although this figure is only 4% less than the estimate of MAGRAMA (2004), regional and local differences are highlighted when the spatial distribution is considered. The model constitutes a comprehensive implementation considering the a
- Published
- 2019
16. CAPACITACION DE LOS ESTUDIANTES DE LA ACTIVIDAD FÍSICA Y EL DEPORTE DE LA UNIVERSIDAD DE METROPOLITANA DE PUERTO RICO EN EL AFRONTAMIENTO DEL ACOSO Y LA VIOLENCIA ESCOLAR.
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López-Burgos, C. A., Rodríguez-Sabiote, C., Álvarez-Rodríguez, J., and Álvarez-Ferrándiz, D.
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SCHOOL violence ,PSYCHOLOGICAL adaptation ,TEACHER training ,TEACHER education ,LIKERT scale ,SCHOOL bullying ,BULLYING - Abstract
Copyright of Journal of Sport & Health Research is the property of Journal of Sport & Health Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2021
17. Genetic but not lean grade impact on growth, carcass traits and pork quality under organic husbandry
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Argemí-Armengol, I., primary, Villalba, D., additional, Ripoll, G., additional, and Álvarez-Rodríguez, J., additional
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- 2019
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18. Credence cues of pork are more important than consumers' culinary skills to boost their purchasing intention
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Argemí-Armengol, I., primary, Villalba, D., additional, Ripoll, G., additional, Teixeira, A., additional, and Álvarez-Rodríguez, J., additional
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- 2019
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19. The fatty acid composition of ewe milk or suckling lamb meat can be used to discriminate between ewes fed different diets
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Lobón, S., primary, Joy, M., additional, Sanz, A., additional, Álvarez-Rodríguez, J., additional, and Blanco, M., additional
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- 2019
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20. PSXIII-1 Relationship between estrus expression detected by four methods and initial GnRH treatment with pregnancy per artificial insemination in suckler cows.
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Sanz, A, primary, Rodríguez-Sánchez, J, additional, Ferrer, J, additional, Álvarez-Rodríguez, J, additional, and Casasús, I, additional
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- 2018
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21. Alfalfa but not milk in lamb's diet improves meat fatty acid profile and α-tocopherol content
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Álvarez-Rodríguez, J., primary, Ripoll, G., additional, Lobón, S., additional, Sanz, A., additional, Blanco, M., additional, and Joy, M., additional
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- 2018
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22. Carcass lean-yield effects on the fatty acid and amino acid composition of Duroc pork and its technological quality after vacuum-aging
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Álvarez-Rodríguez, J., primary, Ros-Freixedes, R., additional, Gol, S., additional, Henríquez-Rodríguez, E., additional, Pena, R. N., additional, Bosch, L., additional, Estany, J., additional, Vilaró, F., additional, and Tor, M., additional
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- 2018
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23. Effect of the metal precursor on the catalytic performance of the Ru/KL system for the ethanol transformation reactions
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Almohalla, M., primary, Gallegos-Suárez, E., additional, Arcoya, A., additional, Álvarez-Rodríguez, J., additional, Rodríguez-Ramos, I., additional, and Guerrero-Ruiz, A., additional
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- 2017
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24. Analysis of geographic and orographic influence in Spanish monthly precipitation
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Álvarez-Rodríguez, J., primary, Llasat, M. C., additional, and Estrela, T., additional
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- 2017
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25. Efectos del uso de lonas térmicas de polipropileno en naves de destete durante el invierno
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Dolz, N., Álvarez-Rodríguez, J., Babot, D., and Forcada, F.
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Sistemas agropascícolas ,Producción animal ,Gestión - Abstract
published Tomo I . Sección: Sistemas Ganaderos-Economía y Gestión. Sesión: Conejos, abejas, peces y cerdos. Ponencia nº 25
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- 2015
26. Nutritional strategies to cope with reduced litter weight gain and total tract digestibility in lactating sows
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Álvarez-Rodríguez, J., primary, Mir, L., additional, Seradj, A. R., additional, Morazán, H., additional, Balcells, J., additional, and Babot, D., additional
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- 2016
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27. Análisis de los factores contribuyentes en incidentes relacionados con la seguridad del paciente en Medicina Intensiva
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Martín Delgado, M.C., primary, Merino de Cos, P., additional, Sirgo Rodríguez, G., additional, Álvarez Rodríguez, J., additional, Gutiérrez Cía, I., additional, Obón Azuara, B., additional, and Alonso Ovies, Á., additional
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- 2015
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28. Analysis of contributing factors associated to related patients safety incidents in Intensive Care Medicine
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Martín Delgado, M.C., primary, Merino de Cos, P., additional, Sirgo Rodríguez, G., additional, Álvarez Rodríguez, J., additional, Gutiérrez Cía, I., additional, Obón Azuara, B., additional, and Alonso Ovies, Á., additional
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- 2015
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29. Comparison of objective measures of pork colour traits during ageing of the longissimus muscle from pigs housed organically and conventionally
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Álvarez-Rodríguez, J., primary, Tor, M., additional, Cubiló, D., additional, Ripoll, G., additional, Babot, D., additional, and Villalba, D., additional
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- 2015
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30. Protocol de vigilància epidemiològica per a la prevenció i el control de l’hepatitis C
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Álvarez-Rodríguez, Josep, Camps-Cura, Neus, Manzanares-Laya, Sandra, Izquierdo, Conchita, [Álvarez-Rodríguez J] Servei de Vigilància i Resposta a Emergències de Salut Pública al Barcelonès Nord Maresme, Sub-direcció Regional a Barcelona, Agència de Salut Pública de Catalunya, Departament de Salut, Generalitat de Catalunya, Barcelona, Spain. [Camps-Cura N] Servei de Vigilància i Resposta a Emergències de Salut Pública, Regió Sanitària Girona, Agència de Salut Pública de Catalunya, Departament de Salut, Generalitat de Catalunya, Barcelona, Spain. [Izquierdo-Gómez C] Sub-direcció General de Vigilància i Resposta a Emergències de Salut Pública, Agència de Salut Pública de Catalunya, Departament de Salut, Generalitat de Catalunya, Barcelona, Spain. [Manzanares-Laya S] Servei d’Epidemiologia, Agència de Salut Pública de Barcelona, Barcelona, Spain. Agència de Salut Pública de Catalunya, Departament de Salut, Generalitat de Catalunya, Barcelona, Spain, and Departament de Salut
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Other subheadings::Other subheadings::/prevention & control [Other subheadings] ,Otros calificadores::Otros calificadores::/prevención & control [Otros calificadores] ,Hepatitis C - Prevenció ,Virus Diseases::Hepatitis, Viral, Human::Hepatitis C [DISEASES] ,virosis::hepatitis viral humana::hepatitis C [ENFERMEDADES] - Abstract
Hepatitis C; Malalties transmissibles; Prevenció Hepatitis C; Enfermedades trasmisibles; Prevención Hepatitis C; Communicable diseases; Prevention Protocolo de actuación dirigido a los profesionales de la salud para el control y la prevención de la hepatitits C Protocol d'actuació dirigit als professionals de la salut per al control i la prevenció de l'hepatitis C Protocol of action aimed at health professionals to the control and prevention of hepatitis C
- Published
- 2018
31. Il sistema sanzionatorio in materia tributaria: principi e limiti nella prospettiva dei diritti del contribuente. Parte II. La prospettiva italiana
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COPPA, Daria, Amatucci, F., Alfano, R., Abbamonte, G., Amatucci, A., Acosta, E., Plazas Vega, M., Fernández Junquera, M., Petrillo, G., González Valencia, J., Checa González, C., Álvarez Rodríguez, J., Vázquez del Rey Villanueva, A., Ciarcia, A., Bejarano Rodríguez, J., De la Peña Velasco, G., Mendoza Méndez, M., Tejerizo López, J., Nastri, M., Plazas Molina, C., García Frías, A., Pistone, P., Plazas-Gómez, C., Simón Yarza, M., Posada García-Peña, M., Soler Roch, M., Bravo González, J., Durán, M., Selicato, P., Cruz de Quiñones, L., and Coppa, D.
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tax, sanctions, taxpayer ,Settore IUS/12 - Diritto Tributario ,sanzione, tributaria, contribuente - Abstract
Il sistema sanzionatorio tributario italiano, improntato ad una spiccata concezione punitiva, è caratterizzato dall'operatività di taluni principi propri del diritto penale. La scelta del legislatore risponde all'esigenza di restituire alle sanzioni tributarie le naturali funzioni afflittiva ed intimidatoria, proprie di tutte le misure punitive, salvaguardando nel contempo il rispetto delle garanzie riconosciute, nel diritto punitivo comune, al soggetto che, avendo leso o anche soltanto messo in pericolo il bene giuridico protetto, deve subire la conseguenza sanzionatoria. Dall'esame della vigente disciplina emerge tuttavia che l’intento di assicurare una giusta conseguenza punitiva non sempre risulta coerentemente perseguito, a causa delle numerose deroghe a quei principi penalistici forse troppo fortemente enfatizzati. Il saggio esamina talune incongruenze riscontrabili nelle previsioni normative che disciplinano i principi di personalità della sanzione, di legalità, imputabilità e intrasmissibilità della sanzione agli eredi, nonché il procedimento di applicazione della misura punitiva e la sua esecuzione. The Italian tax sanctioning system, based on a marked punitive concept, is characterized by the effectiveness of certain principles of criminal law. The legislator's choice to responds to the need to restore to tax sanctions the natural afflictive and intimidating functions, proper of all punitive measures, while safeguarding compliance with the guarantees recognized, in shared criminal law, to the subject who, having harmed or even only endangered the protected legal good, must suffer the sanctioning consequence. However, from the examination of the current legislation it emerges that the aim of ensuring a fair punitive consequence is not always consistently pursued, due to the numerous exceptions to those penal principles that are perhaps too strongly emphasized. The essay examines certain inconsistencies found in the regulatory provisions regulating the principles of personality of the penalty, legality, imputability and non-transferability of the sanction to the heirs, as well as the procedure for applying the punitive measure and its execution.
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- 2017
32. Combatting resistance in intensive care: the multimodal approach of the Spanish ICU 'Zero Resistance' program
- Author
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Garnacho Montero, José, Álvarez Lerma, Francisco, Ramírez Galleymore, Paula, Palomar Martínez, Mercedes, Álvarez Rocha, Luis, Barcenilla Gaite, Fernando, Álvarez Rodríguez, Joaquín, Catalán González, Mercedes, Fernández Moreno, Inmaculada, Rodríguez Baño, Jesús, Campos, José, Aranaz Andrés, Jesús Ma, Agra Varela, Yolanda, Rodríguez Gay, Carolina, Sánchez García, Miguel, [Garnacho Montero,J] Hospital Vírgen del Rocío, Sevilla, Spain. [Álvarez Lerma,F] Hospital del Mar, Barcelona, Spain. [Ramírez Galleymore,P] Hospital La Fé, Valencia, Spain. [Palomar Martínez,M] Hospital Arnau de Vilanova, Lérida, Spain. [Álvarez Rocha,L] Complejo Hospitalario La Coruña, La Coruña, Spain. [Barcenilla Gaite,F] Hospital Arnau de Vilanova, Lérida, Spain. [Álvarez Rodríguez,J] Hospital de Fuenlabrada, Fuenlabrada, Madrid, Spain. [Catalán González,M] Hospital Doce de Octubre, Madrid, Spain. [Fernández Moreno,I] Hospital Parc Taulí, Sabadell, Barcelona, Spain. [Rodríguez Baño,J] Hospital Vírgen Macarena, Sevilla, Spain. [Campos,J] Centro Nacional de Microbiología, Majadahonda, Madrid, Spain. [Aranaz Andrés,JM] Hospital Ramón y Cajal, Madrid, Spain. [Agra Varela,Y, Rodríguez Gay,C] Spanish Ministry of Health, Madrid, Spain. [Sánchez García,M] Hospital Clínico San Carlos, Madrid, Spain., and Publication of this article was funded by Subdireccion General de Calidad y Cohesion of the Spanish Ministry of Health.
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Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Patient Care::Critical Care::Intensive Care [Medical Subject Headings] ,España ,Diseases::Bacterial Infections and Mycoses::Infection::Cross Infection [Medical Subject Headings] ,Disciplines and Occupations::Health Occupations::Medicine::Emergency Medicine [Medical Subject Headings] ,Cuidados intensivos ,Disciplines and Occupations::Health Occupations::Medicine::Public Health [Medical Subject Headings] ,Health Care::Health Care Facilities, Manpower, and Services::Health Facilities::Hospital Units::Intensive Care Units [Medical Subject Headings] ,Carbapenémicos ,Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings] ,Organisms::Bacteria::Gram-Negative Bacteria::Gram-Negative Aerobic Bacteria::Gram-Negative Aerobic Rods and Cocci::Moraxellaceae::Acinetobacter::Acinetobacter baumannii [Medical Subject Headings] ,Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Incidence [Medical Subject Headings] ,Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Drug Resistance::Drug Resistance, Multiple [Medical Subject Headings] ,Chemicals and Drugs::Organic Chemicals::Amides::Lactams::beta-Lactams [Medical Subject Headings] ,Diseases::Bacterial Infections and Mycoses::Bacterial Infections::Gram-Negative Bacterial Infections::Enterobacteriaceae Infections::Klebsiella Infections [Medical Subject Headings] ,Bacterias grampositivas ,Organisms::Bacteria::Endospore-Forming Bacteria::Gram-Positive Endospore-Forming Bacteria::Gram-Positive Endospore-Forming Rods::Staphylococcaceae::Staphylococcus::Staphylococcus aureus::Methicillin-Resistant Staphylococcus aureus [Medical Subject Headings] ,Geographicals::Geographic Locations::Europe::Spain [Medical Subject Headings] ,Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Amidohydrolases::beta-Lactamases [Medical Subject Headings] ,Organisms::Bacteria::Gram-Negative Bacteria::Gram-Negative Aerobic Bacteria::Gram-Negative Aerobic Rods and Cocci::Pseudomonadaceae::Pseudomonas::Pseudomonas aeruginosa [Medical Subject Headings] ,Geographicals::Geographic Locations::Europe [Medical Subject Headings] ,Organisms::Bacteria::Gram-Negative Bacteria::Gram-Negative Facultatively Anaerobic Rods::Enterobacteriaceae::Escherichia::Escherichia coli [Medical Subject Headings] ,Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Patient Care::Hospitalization [Medical Subject Headings] ,Antibacterianos ,Organisms::Bacteria::Gram-Positive Bacteria [Medical Subject Headings] ,Disciplines and Occupations::Social Sciences::Cost of Illness [Medical Subject Headings] ,Chemicals and Drugs::Organic Chemicals::Amides::Lactams::beta-Lactams::Penicillins::Methicillin [Medical Subject Headings] ,Chemicals and Drugs::Carbohydrates::Glycoconjugates::Glycopeptides::Vancomycin [Medical Subject Headings] ,Organisms::Bacteria::Gram-Positive Bacteria::Lactobacillales::Enterococcaceae::Enterococcus [Medical Subject Headings] ,Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis [Medical Subject Headings] ,Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents [Medical Subject Headings] ,Organisms::Bacteria::Gram-Negative Bacteria::Gram-Negative Facultatively Anaerobic Rods::Enterobacteriaceae::Klebsiella::Klebsiella pneumoniae [Medical Subject Headings] ,Chemicals and Drugs::Organic Chemicals::Amides::Lactams::beta-Lactams::Monobactams [Medical Subject Headings] ,Chemicals and Drugs::Organic Chemicals::Amides::Lactams::beta-Lactams::Carbapenems [Medical Subject Headings] ,Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Anti-Bacterial Agents [Medical Subject Headings] - Abstract
Journal Article; This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2015 and co-published as a series in Critical Care. Other articles in the series can be found online at http://ccforum.com/series/annualupdate2015. Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901. Yes
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- 2015
33. Genetic variants regulating the immune response improve the prediction of COVID-19 severity provided by clinical variables.
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Delgado-Wicke P, Fernández de Córdoba-Oñate S, Roy-Vallejo E, Alegría-Carrasco E, Rodríguez-Serrano DA, Lamana A, Montes N, Nicolao-Gómez A, Carracedo-Rodríguez R, Marcos-Jiménez A, Díaz-Fernández P, Galván-Román JM, Rabes-Rodríguez L, Sanz-Alba M, Álvarez-Rodríguez J, Villa-Martí A, Rodríguez-Franco C, Villapalos-García G, Zubiaur P, Abad-Santos F, de Los Santos I, Gomariz RP, García-Vicuña R, Muñoz-Calleja C, González-Álvaro I, and Fernández-Ruiz E
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- Humans, Male, Female, Middle Aged, Aged, Adult, Toll-Like Receptor 7 genetics, TYK2 Kinase genetics, Genotype, Genetic Predisposition to Disease, 2',5'-Oligoadenylate Synthetase genetics, COVID-19 genetics, COVID-19 immunology, COVID-19 virology, Polymorphism, Single Nucleotide, Severity of Illness Index, SARS-CoV-2 genetics, SARS-CoV-2 immunology
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The characteristics of the host are crucial in the final outcome of COVID-19. Herein, the influence of genetic and clinical variants in COVID-19 severity was investigated in a total of 1350 patients. Twenty-one single nucleotide polymorphisms of genes involved in SARS-CoV-2 sensing as Toll-like-Receptor 7, antiviral immunity as the type I interferon signalling pathway (TYK2, STAT1, STAT4, OAS1, SOCS) and the vasoactive intestinal peptide and its receptors (VIP/VIPR1,2) were studied. To analyse the association between polymorphisms and severity, a model adjusted by age, sex and different comorbidities was generated by ordinal logistic regression. The genotypes rs8108236-AA (OR 0.12 [95% CI 0.02-0.53]; p = 0.007) and rs280519-AG (OR 0.74 [95% CI 0.56-0.99]; p = 0.03) in TYK2, and rs688136-CC (OR 0.7 [95% CI 0.5-0.99]; p = 0.046) in VIP, were associated with lower severity; in contrast, rs3853839-GG in TLR7 (OR 1.44 [95% CI 1.07-1.94]; p = 0.016), rs280500-AG (OR 1.33 [95% CI 0.97-1.82]; p = 0.078) in TYK2 and rs1131454-AA in OAS1 (OR 1.29 [95% CI 0.95-1.75]; p = 0.110) were associated with higher severity. Therefore, these variants could influence the risk of severe COVID-19., (© 2024. The Author(s).)
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- 2024
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34. Fattening Pigs with Tannin-Rich Source ( Ceratonia siliqua L.) and High Doses of Vitamin E: Effects on Growth Performance, Economics, Digestibility, Physiology, and Behaviour.
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Bottegal DN, Latorre MÁ, Lobón S, Verdú M, and Álvarez-Rodríguez J
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This study aimed to assess the impact on growth, economic results, apparent nutrient digestibility (CTTAD), physiological variables, and animal behaviour when 214 fattening pigs (78 ± 8.5 kg of initial body weight and 130 ± 4.5 days of age) of both sexes (gilts and boars) were fed two levels of carob pulp (Cp, 0 vs. 20%) and two doses of vitamin E (Vit E, 30 vs. 300 IU/kg) for 40 days. No interaction effects between factors studied (Cp, Vit E, and sex) were observed on the variables. Most productive traits were unaffected by Cp or Vit E inclusion. However, the Cp increased the feed conversion ratio during the first 20 days. The Cp group showed a higher CTTAD of ether extract and hemicellulose but lower CTTAD of crude protein. Pigs fed Cp had a lower plasmatic urea content than the control group. The high Vit E doses increased the CTTAD of every nutrient and the plasmatic α-tocopherol content. The pigs fed Cp tended to spend more time eating in the early morning, likely to mitigate tannins' astringent effects. Dietary inclusion of 20% Cp in finishing high-conformation pigs is possible without affecting overall performance though it reduces nutrient CTTAD and increases feeding cost. Supra-nutritional doses of Vit E do not affect pig performance but increase the α-tocopherol deposition with potential antioxidant effects.
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- 2024
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35. Improving the Meat and Meat Product Quality of Rare Pork Breeds and Genetic Types.
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Teixeira A and Álvarez-Rodríguez J
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Pork is the most consumed meat globally, particularly in Asia, Europe, and America [...].
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- 2024
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36. Clinical characteristics and outcomes of aortic prosthetic valve endocarditis: comparison between transcatheter and surgical bioprostheses.
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Jerónimo A, Olmos C, Zulet P, Gómez-Ramírez D, Anguita M, Carlos Castillo J, Escrihuela-Vidal F, Cuervo G, Calderón-Parra J, Ramos A, Cabezón G, Álvarez Rodríguez J, Pulido P, de Miguel-Álava M, Sáez C, López J, Vilacosta I, and San Román JA
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Purpose: Most data regarding infective endocarditis (IE) after transcatheter aortic valve implantation (TAVI) comes from TAVI registries, rather than IE dedicated cohorts. The objective of our study was to compare the clinical and microbiological profile, imaging features and outcomes of patients with IE after SAVR with a biological prosthetic valve (IE-SAVR) and IE after TAVI (IE-TAVI) from 6 centres with an Endocarditis Team (ET) and broad experience in IE., Methods: Retrospective analysis of prospectively collected data. From the time of first TAVI implantation in each centre to March 2021, all consecutive patients admitted for IE-SAVR or IE-TAVI were prospectively enrolled. Follow-up was monitored during admission and at 12 months after discharge., Results: 169 patients with IE-SAVR and 41 with IE-TAVI were analysed. Early episodes were more frequent among IE-TAVI. Clinical course during hospitalization was similar in both groups, except for a higher incidence of atrioventricular block in IE-SAVR. The most frequently causative microorganisms were S. epidermidis, Enterococcus spp. and S. aureus in both groups. Periannular complications were more frequent in IE-SAVR. Cardiac surgery was performed in 53.6% of IE-SAVR and 7.3% of IE-TAVI (p=0.001), despite up to 54.8% of IE-TAVI patients had an indication. No differences were observed about death during hospitalization (32.7% vs 35.0%), and at 1-year follow-up (41.8% vs 37.5%), regardless of whether the patient underwent surgery or not., Conclusion: Patients with IE-TAVI had a higher incidence of early prosthetic valve IE. Compared to IE-SAVR, IE-TAVI patients underwent cardiac surgery much less frequently, despite having surgical indications. However, in-hospital and 1-year mortality rate was similar between both groups., (© 2024. The Author(s).)
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- 2024
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37. Tools for the identification of victims of domestic abuse and modern slavery in remote services: A systematic review.
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Tomsett B, Álvarez-Rodríguez J, Sherriff N, Edelman N, and Gatuguta A
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Objective: To explore the technology-based tools available for supporting the identification of victims of domestic abuse and modern slavery in remote services and consider the benefits and challenges posed by the existing tools., Methods: We searched six academic databases. Studies were considered for inclusion if they were published in English between 2000 and 2023. The QuADS quality appraisal tool was used to assess the methodological quality of included studies. A narrative synthesis was conducted using the convergent integrated approach., Results: Twenty-four studies were included, of which two were professional guidelines; each reported on a distinct technology-based tool for remote services. All tools related to domestic abuse and 21 focused on screening for intimate partner violence among young and mid-life women (18-65) in high-income countries. The review did not identify tools that support the identification of victims of modern slavery. We identified eight common themes of tool strengths, highlighting that the remote approach to screening was practical, acceptable to victims, and, in some circumstances, elicited better outcomes than face-to-face approaches. Five themes pointed to tool challenges, such as concerns around privacy and safety, and the inability of computerised tools to provide empathy and emotional support., Conclusions: Available technology-based tools may support the identification of victims of domestic abuse by health and social care practitioners in remote services. However, it is important to be mindful of the limitations of such tools and the effects individuals' screening preferences can have on outcomes. Future research should focus on developing tools to support the identification of victims of modern slavery, as well as empirically validating tools for screening during remote consultations., Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
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- 2024
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38. A Preliminary Evaluation of Sex and Dietary Field Pea Effects on Sensory Characteristics of Dry-Cured Loins.
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Argemí-Armengol I, Álvarez-Rodríguez J, Tor M, Salada L, Leite A, Vasconcelos L, Teixeira A, and Rodrigues SSQ
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Two of the main issues related to cured meat products are castration to avoid boar taint and the hefty reliance on soybean meal to feed pigs. However, data on the effects of immunocastration in pigs and alternative crop protein feeds on the sensory traits and consumers' acceptance of dry-cured loin are still limited. A preliminary study was conducted on the effect of sex type (surgical castrated male pigs and immunocastrated male and female pigs, at approximately 140 kg in weight and 7 months of age) and animal diet (pea vs. soya) on dry-cured loins. The study involved a sensory evaluation of six treatments, with a 3 × 2 factorial design, conducted by trained panellists and untrained consumers in Spain ( n = 126) and Portugal ( n = 80). The consumers were also checked for their skatole sensitivity using a pure substance. The results showed that the pea-based diet was significantly different ( p < 0.001) from the soy-based diet, as determined by a trained panel of surgically castrated male pigs, although the immunocastration treatments were not split. Dry-cured loin from immunocastrated male pigs fed with peas was considered tenderer and juicier ( p < 0.05) than those fed soya-based diets. The untrained consumer panel scored higher on the sensory traits (flavour, juiciness, and overall liking) from the loin samples of surgically castrated male pigs fed a pea diet. All consumers scored similarly in boar taint detection. This study demonstrates the applicability of the pea-based diet for the feeding of pigs destined for cured meat and highlights immunocastration as a tool that does not compromise the skatole detection score.
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- 2024
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39. Impact of carob (Ceratonia siliqua L.) pulp inclusion and warm season on gastrointestinal morphological parameters, immune-redox defences and coccidiosis in concentrate-fed light lambs.
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Pelegrin-Valls J, Álvarez-Rodríguez J, Martín-Alonso MJ, Aquilué B, and Serrano-Pérez B
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- Sheep, Animals, Antioxidants, Seasons, Sheep, Domestic, Oxidation-Reduction, Coccidiosis veterinary, Sheep Diseases prevention & control
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This study aimed to evaluate the effects of dietary carob (Ceratonia siliqua L.) pulp and warm season on gastrointestinal morphological parameters, immune-redox defences and coccidiosis in concentrate-fed light lambs. Weaned lambs were assigned to one of three concentrate-based diets: C0 (without carob pulp), C15 (150 g/kg of carob pulp) and C30 (300 g/kg of carob pulp) from 40 to 80 days of age in two consecutive cold and warm batches. Blood samples were collected at Day 80 to determine the metabolic status. Rectal faeces were sampled at Days 50, 65 and 80 to determine consistency and oocyst count per gram. Inclusion of carob pulp in lamb diets did not affect lamb growth but reduced coccidia oocyst excretion, improved faecal consistency and gastrointestinal morphological parameters, enhancing the ruminal thickness of the papilla living strata and reducing the darkness of the epithelium colour. Moreover, carob condensed tannins in the lambs' diet enhanced the expression of antioxidant SOD2 in rumen, while down-regulated NRF2, SOD1, CAT and PPARG in ileum. There was no interaction between the treatments and season in the evaluated variables. Lambs from the warm season exhibited reduced growth performance, altered ruminal epithelium, lower circulating iron levels, increased protein concentrations and higher coccidiosis susceptibility. In addition, regulatory immune and antioxidant mechanisms to counterbalance reactive oxygen species production in gastrointestinal tissues were evident. Dietary inclusion of carob pulp (150 and 300 g/kg) in lamb diets improved gastrointestinal health and homeostasis but did not ameliorate the deleterious effects of warm season., Competing Interests: Declaration of Competing Interest None., (Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.)
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- 2023
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40. Extracorporeal membrane oxygenation (ECMO) and beyond in near fatal asthma: A comprehensive review.
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Lozano-Espinosa M, Antolín-Amérigo D, Riera J, Gordo Vidal F, Quirce S, and Álvarez Rodríguez J
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- Adult, Child, Humans, Extracorporeal Membrane Oxygenation methods, Asthma therapy, Asthma etiology, Respiratory Insufficiency etiology, Respiratory Insufficiency therapy
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The treatment of choice in severe asthma exacerbations with respiratory failure includes ventilatory support, both invasive and/or non-invasive, along with different kinds of asthma medication. Of note, the rate of mortality of patients with asthma has decreased substantially in recent years mainly due to significant advances in pharmacological treatment and other management strategies. However, the risk of death in patients with severe asthma who require invasive mechanical ventilation has been estimated between 6.5% and 10.3%. When conventional measures fail, rescue strategies, such as extracorporeal membrane oxygenation (ECMO) or extracorporeal CO2 removal (ECCO2R) may need to be implemented. While ECMO does not constitute a definitive treatment per se, it can minimize further ventilator associated lung injury (VALI) and can enable diagnostic-therapeutic maneuvers that cannot be performed without ECMO such as bronchoscopy and transfer for diagnostic imaging. Asthma is one of the diseases that is associated with excellent outcomes for patients with refractory respiratory failure requiring ECMO support, as shown by the Extracorporeal Life Support Organization (ELSO) registry. Moreover, in such situations, the use of ECCO2R for rescue has been described and utilized in both children and adults and is more widely spread in different hospitals than ECMO. In this article, we aim to review the evidence for the usefulness of extracorporeal respiratory support measures in the management of severe asthma exacerbations that lead to respiratory failure., Competing Interests: Declaration of competing interest The authors of the article “Near Fatal Asthma and Extracorporeal Respiratory Support: a comprehensive review report no conflicts of interest., (Copyright © 2023 Elsevier Ltd. All rights reserved.)
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- 2023
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41. Colour Stability, Fatty Acid Profile, and Lipid Oxidation in Meat Stored in Modified Atmosphere Packaging from Light Lambs Fed with Concentrate with Carob Pulp ( Ceratonia siliqua L.).
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Bottegal DN, Lobón S, Latorre MÁ, Bertolín JR, and Álvarez-Rodríguez J
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There is a growing interest in using by-products rich in polyphenols, such as carob pulp (Cp, Ceratonia siliqua L.), as a dietary source of antioxidants for animals. This study assesses the effects of including Cp in lambs' diet and meat display time (0, 7, 9, and 11 days) in modified atmosphere packaging on meat colour, fatty acid (FA) composition, tocopherol levels, and lipid oxidation values in the Semimembranosus muscle of 40 light lambs. The lambs were fed with concentrates supplemented with increasing Cp levels (0, 150, and 300 g/kg) for 45 days before slaughter. Metmyoglobin (MMb) and malondialdehyde (MDA) contents increased linearly with display time ( p < 0.05), regardless of diet ( p > 0.05). At 11 days of display, MMb (28 ± 0.8%) and MDA (0.6 ± 0.1 mg MDA/kg of meat) contents remained within the acceptable limits. The α-tocopherol content was lower in the 30% Cp group and meat ( p < 0.05). Total saturated and monounsaturated FA contents (934 ± 64 and 823 ± 65 mg/100 g of meat, respectively) did not differ significantly among the groups. However, the meat from lambs fed with 30% Cp showed reduced levels of branched-chain FAs, while polyunsaturated FAs increased ( p < 0.05) compared to the control lambs. The inclusion of Cp in the lamb's diet, up to 30%, did not lead to meat deterioration and improved certain quality parameters, including a healthier FA profile. These findings highlight Cp's potential as an alternative antioxidant source in animal diets.
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- 2023
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42. Dimensionality reduction and ensemble of LSTMs for antimicrobial resistance prediction.
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Hernàndez-Carnerero À, Sànchez-Marrè M, Mora-Jiménez I, Soguero-Ruiz C, Martínez-Agüero S, and Álvarez-Rodríguez J
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- Humans, Drug Resistance, Bacterial, Neural Networks, Computer, Intensive Care Units, Anti-Bacterial Agents therapeutic use, Bacterial Infections drug therapy
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Bacterial resistance to antibiotics has been rapidly increasing, resulting in low antibiotic effectiveness even treating common infections. The presence of resistant pathogens in environments such as a hospital Intensive Care Unit (ICU) exacerbates the critical admission-acquired infections. This work focuses on the prediction of antibiotic resistance in Pseudomonas aeruginosa nosocomial infections at the ICU, using Long Short-Term Memory (LSTM) artificial neural networks as the predictive method. The analyzed data were extracted from the Electronic Health Records (EHR) of patients admitted to the University Hospital of Fuenlabrada from 2004 to 2019 and were modeled as Multivariate Time Series. A data-driven dimensionality reduction method is built by adapting three feature importance techniques from the literature to the considered data and proposing an algorithm for selecting the most appropriate number of features. This is done using LSTM sequential capabilities so that the temporal aspect of features is taken into account. Furthermore, an ensemble of LSTMs is used to reduce the variance in performance. Our results indicate that the patient's admission information, the antibiotics administered during the ICU stay, and the previous antimicrobial resistance are the most important risk factors. Compared to other conventional dimensionality reduction schemes, our approach is able to improve performance while reducing the number of features for most of the experiments. In essence, the proposed framework achieve, in a computationally cost-efficient manner, promising results for supporting decisions in this clinical task, characterized by high dimensionality, data scarcity, and concept drift., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.)
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- 2023
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43. Relevant SARS-CoV-2 viremia is associated with COVID-19 severity: Prospective cohort study and validation cohort.
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Cardeñoso Domingo L, Roy Vallejo E, Zurita Cruz ND, Chicot Llano M, Ávalos Pérez-Urria E, Barrios A, Hernando Santos J, Ortiz J, Rodríguez García SC, Martín Ramírez A, Ciudad Sañudo M, Marcos C, García Castillo E, Fontán García-Rodrigo L, González B, Méndez R, Iturrate I, Sanz García A, Villa A, Sánchez Azofra A, Quicios B, Arribas D, Álvarez Rodríguez J, Patiño P, Trigueros M, Uriarte M, Triguero Martínez A, Arévalo C, Galván Román JM, García-Vicuña R, Ancochea J, Soriano JB, Canabal A, Muñoz Calleja C, De la Cámara R, Suarez Fernández C, González Álvaro I, and Rodríguez-Serrano DA
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- Adult, Hospitalization, Humans, Prospective Studies, Retrospective Studies, SARS-CoV-2, Viremia, COVID-19 diagnosis
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Early kinetics of SARS-CoV-2 viral load (VL) in plasma determined by quantitative reverse-transcription polymerase chain reaction (RT-PCR) was evaluated as a predictor of poor clinical outcome in a prospective study and assessed in a retrospective validation cohort. Prospective observational single-center study including consecutive adult patients hospitalized with COVID-19 between November 2020 and January 2021. Serial plasma samples were obtained until discharge. Quantitative RT-PCR was performed to assess SARS-CoV-2 VL. The main outcomes were in-hospital mortality, admission to the Intensive Care Unit (ICU), and their combination (Poor Outcome). Relevant viremia (RV), established in the prospective study, was assessed in a retrospective cohort including hospitalized COVID-19 patients from April 2021 to May 2022, in which plasma samples were collected according to clinical criteria. Prospective cohort: 57 patients were included. RV was defined as at least a twofold increase in VL within ≤2 days or a VL > 300 copies/ml, in the first week. Patients with RV (N = 14; 24.6%) were more likely to die than those without RV (35.7% vs. 0%), needed ICU admission (57% vs. 0%) or had Poor Outcome (71.4% vs. 0%), (p < 0.001 for the three variables). Retrospective cohort: 326 patients were included, 18.7% presented RV. Patients with RV compared with patients without RV had higher rates of ICU-admission (odds ratio [OR]: 5.6 [95% confidence interval [CI]: 2.1-15.1); p = 0.001), mortality (OR: 13.5 [95% CI: 6.3-28.7]; p < 0.0001) and Poor Outcome (OR: 11.2 [95% CI: 5.8-22]; p < 0.0001). Relevant SARS-CoV-2 viremia in the first week of hospitalization was associated with higher in-hospital mortality, ICU admission, and Poor Outcome. Findings observed in the prospective cohort were confirmed in a larger validation cohort., (© 2022 The Authors. Journal of Medical Virology published by Wiley Periodicals LLC.)
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- 2022
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44. Knowledge structures of scientific production on COVID-19 in the sphere of education: the case of publications indexed in the Web of Science during 2020.
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Rodríguez-Sabiote C, Úbeda-Sánchez ÁM, Lorenzo-Quiles O, and Álvarez-Rodríguez J
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This study seeks to explore the different knowledge structures in the sphere of educational research into COVID-19 during 2020. Using bibliometric methods, analysis was performed of a sample of 308 scientific articles retrieved from the Web of Science database. Using different data analysis techniques combining co-occurrence analysis, co-citation analysis and factorial analysis, All Keywords and Keywords Plus were used to achieve the main research objective: identification of the main themes and trends of production in the sphere of educational research into COVID-19. The main findings of this study in terms of the conceptual structure show that analysis of the centrality and density of the thematic trends points to a generalised structural change in the entire educational system towards methodological teaching-learning procedures oriented towards distance education. As for the intellectual structure, among the host of authors and sources of information involved only a select few have a greater influence on the scientific community. Finally, in terms of social structure, there is limited collaboration between authors and institutions from different countries. However, this collaboration is more intense within countries themselves and in terms of their own production, with the USA being the country with the strongest links., (© The Author(s) 2022.)
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- 2022
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45. Locally Grown Crops and Immunocastration in Fattening Heavy Pigs: Effects on Performance and Welfare.
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Argemí-Armengol I, Villalba D, Vall L, Coma R, Roma J, and Álvarez-Rodríguez J
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This study aimed to explore dietary replacement soybean meal (SBM) with local pea seeds (PS-L) and the effects of surgically castrated (CM) or immunocastration (IM) in heavy male pigs, on growth performance, feeding behaviour, and tail and ear lesions. Four treatments were arranged factorially (2 × 2), with two sexes and two dietary treatments (96 pigs in eight pens). The inclusion of PS-L was 25%, 30%, and 40% during three phases (40−80 kg, 80−110 kg, and 110−140 kg, respectively). No difference in average daily feed intake (ADFI) and body-weight (BW) between PS-L and SBM could be demonstrated (p > 0.05), but PS-L diet decreased the average daily gain (ADG) at 110−140 kg of BW (p < 0.001) and increased feed conversion rate (FCR) (p < 0.05). The ADG was higher (p < 0.01) in IM than CM in all fattening periods, and the FCR in IM was lower (p < 0.05) than in barrows. IM pigs had lower dressing percentage than CM (p < 0.01). Pigs fed a PS-L diet ate faster but increased their passive behaviour compared with those fed SBM. In conclusion, the PS-L diet did not reduce BW and improved passive behaviour, and IM grew more efficiently, regardless of diet.
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- 2022
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46. SARS-CoV-2 Viremia Precedes an IL6 Response in Severe COVID-19 Patients: Results of a Longitudinal Prospective Cohort.
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Roy-Vallejo E, Cardeñoso L, Triguero-Martínez A, Chicot Llano M, Zurita N, Ávalos E, Barrios A, Hernando J, Ortiz J, Rodríguez-García SC, Ciudad Sañudo M, Marcos C, García Castillo E, Fontán García-Rodrigo L, González B, Méndez R, Iturrate I, Sanz-García A, Villa A, Sánchez-Azofra A, Quicios B, Arribas D, Álvarez Rodríguez J, Patiño P, Trigueros M, Uriarte M, Martín-Ramírez A, Arévalo Román C, Galván-Román JM, García-Vicuña R, Ancochea J, Muñoz-Calleja C, Fernández-Ruiz E, de la Cámara R, Suárez Fernández C, González-Álvaro I, and Rodríguez-Serrano DA
- Abstract
Background: Interleukin 6 (IL6) levels and SARS-CoV-2 viremia have been correlated with COVID-19 severity. The association over time between them has not been assessed in a prospective cohort. Our aim was to evaluate the relationship between SARS-CoV-2 viremia and time evolution of IL6 levels in a COVID-19 prospective cohort., Methods: Secondary analysis from a prospective cohort including COVID-19 hospitalized patients from Hospital Universitario La Princesa between November 2020 and January 2021. Serial plasma samples were collected from admission until discharge. Viral load was quantified by Real-Time Polymerase Chain Reaction and IL6 levels with an enzyme immunoassay. To represent the evolution over time of both variables we used the graphic command twoway of Stata., Results: A total of 57 patients were recruited, with median age of 63 years (IQR [53-81]), 61.4% male and 68.4% Caucasian. The peak of viremia appeared shortly after symptom onset in patients with persistent viremia (more than 1 sample with > 1.3 log10 copies/ml) and also in those with at least one IL6 > 30 pg/ml, followed by a progressive increase in IL6 around 10 days later. Persistent viremia in the first week of hospitalization was associated with higher levels of IL6. Both IL6 and SARS-CoV-2 viral load were higher in males, with a quicker increase with age., Conclusion: In those patients with worse outcomes, an early peak of SARS-CoV-2 viral load precedes an increase in IL6 levels. Monitoring SARS-CoV-2 viral load during the first week after symptom onset may be helpful to predict disease severity in COVID-19 patients., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Roy-Vallejo, Cardeñoso, Triguero-Martínez, Chicot Llano, Zurita, Ávalos, Barrios, Hernando, Ortiz, Rodríguez-García, Ciudad Sañudo, Marcos, García Castillo, Fontán García-Rodrigo, González, Méndez, Iturrate, Sanz-García, Villa, Sánchez-Azofra, Quicios, Arribas, Álvarez Rodríguez, Patiño, Trigueros, Uriarte, Martín-Ramírez, Arévalo Román, Galván-Román, García-Vicuña, Ancochea, Muñoz-Calleja, Fernández-Ruiz, de la Cámara, Suárez Fernández, González-Álvaro, Rodríguez-Serrano and the PREDINMUN-COVID Group.)
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- 2022
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47. Effect of Castration Type and Diet on Growth Performance, Serum Sex Hormones and Metabolites, and Carcass Quality of Heavy Male Pigs.
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Pérez-Ciria L, Miana-Mena FJ, Álvarez-Rodríguez J, and Latorre MA
- Abstract
A trial was carried out to study the effect of type of castration and diet on pigs destined for Teruel ham production, which is a Spanish protected designation of origin for dry-cured ham. A total of 144 Duroc × (Landrace × Large White) male pigs were used. Half of them were surgically castrated and the other half were immunocastrated with three doses at approximately 25, 58 and 79 kg of body weight. Furthermore, three diets (control vs. high energy vs. low crude protein-CP- and amino acids-AA) were tested from 80 to 137 kg of body weight. Growth performance, serum sex hormones and metabolites, and carcass quality were evaluated. Immunocastrated males grew faster and had better feed conversion ratio than surgically castrated males, but presented lower carcass fatness. Pigs fed the high-energy diet and the low-CP and -AA diet were more efficient at transforming feed into gain than those fed the control diet, but no effect was detected on carcass quality. In conclusion, surgically castrated males are preferable than immunocastrated males for Teruel dry-cured ham elaboration. Besides, a high-energy diet or a low-CP and -AA diet might improve productive performances, but does not provide any benefit in terms of carcass quality.
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- 2022
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48. Insights into the role of major bioactive dietary nutrients in lamb meat quality: a review.
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Álvarez-Rodríguez J, Urrutia O, Lobón S, Ripoll G, Bertolín JR, and Joy M
- Abstract
Feed supplementation with α-linolenic acid (ALA) and linoleic acid (LA) increases their content in muscle, ALA increases n-3 polyunsaturated fatty acids and decrease n-6/n-3 ratio in muscle, and LA increases rumenic acid. However, high LA supplementation may have negative effects on lambs' lipid oxidative stability of meat. When the sources of ALA and LA are fed as fresh forage, the negative effects are counterbalanced by the presence of other bioactive compounds, as vitamin E (mainly α-tocopherol) and polyphenols, which delay the lipid oxidation in meat. There is a wide consensus on the capability of vitamin E delaying lipid oxidation on lamb meat, and its feed content should be adjusted to the length of supplementation. A high dietary inclusion of proanthocyanidins, phenolic compounds and terpenes reduce the lipid oxidation in muscle and may improve the shelf life of meat, probably as a result of a combined effect with dietary vitamin E. However, the recommended dietary inclusion levels depend on the polyphenol type and concentration and antioxidant capacity of the feedstuffs, which cannot be compared easily because no routine analytical grading methods are yet available. Unless phenolic compounds content in dietary ingredients/supplements for lambs are reported, no specific association with animal physiology responses may be established., (© 2022. The Author(s).)
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- 2022
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49. The Influence of the Locus of Control Construct on the Efficacy of Physiotherapy Treatments in Patients with Chronic Pain: A Systematic Review.
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Álvarez-Rodríguez J, Leirós-Rodríguez R, Morera-Balaguer J, Marqués-Sánchez P, and Rodríguez-Nogueira Ó
- Abstract
The biopsychosocial paradigm contemplates the patient's personality traits in physiotherapy treatments for chronic pain. Among these traits, the locus of control has a direct relationship with the person's coping strategies in the face of their health problems. The objective of this systematic review was to assess the influence of locus of control on the efficacy of physiotherapy treatments in patients with chronic pain. A systematic review of the publications of the last ten years in Pubmed, Scopus, Science Direct and Web of Science databases was conducting with the terms physical therapy modalities, chronic pain, internal-external control, self-management, physical therapy and physiotherapy. The inclusion criteria were participants with chronic pain lasting at least three months who have received at least one session of physical therapy; the studies should have collected the patient's locus of control as a prognostic factor at the beginning of physiotherapy treatment; the variables studied should include the pain intensity or clinical variables related to pain. A total of 13 articles were found, of which three were experimental studies and ten were observational studies. The included samples had chronic knee pain, nonspecific back pain, low back pain or neck pain; were people over 65 years of age or patients who had undergone hand surgery. In patients with chronic pain for more than three months, the locus of control construct participates as a predictor of the results of physiotherapy treatment. The presence of an internal locus of control favors better results. The personality traits of the subjects represent an important factor to take into account when planning physiotherapy treatments.
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- 2022
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50. Influence of Immunocastration and Diet on Meat and Fat Quality of Heavy Female and Male Pigs.
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Pérez-Ciria L, Miana-Mena FJ, López-Mendoza MC, Álvarez-Rodríguez J, and Latorre MA
- Abstract
Two experiments were carried out; one with female pigs and the other with male pigs destined for Teruel dry-cured ham production, to evaluate the effect of immunocastration (entire gilts-EG vs. immunocastrated gilts-IG and surgically castrated males vs. immunocastrated males-IM) and diet (control vs. high energy vs. low crude protein and amino acids) on meat quality and fat composition. Fifteen meat samples and eight fat samples of each treatment were analyzed in both experiments. In the case of males, six fat samples per treatment were analyzed to determine boar taint. Immunocastration is a good strategy in gilts intended for dry-cured ham production because improves meat composition; however, in males, immunocastration impairs the results of pork chemical composition compared with surgical castration. The IG presented a lower polyunsaturated/saturated fatty acids ratio than EG, improving fat technological quality. Diets had little effect on pork or fat quality in gilts, but a high-energy level using oilseeds and a low-crude-protein and -amino-acids diet from 80 to 137 kg of body weight could be interesting in IM to maintain or increase fat consistency, respectively. Moreover, in general, immunocastration is effective in avoiding boar taint in males.
- Published
- 2021
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