1. Clinical and Angiographic Features of Patients With Out-of-Hospital Cardiac Arrest and Acute Myocardial Infarction.
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Kosugi, Shumpei, Shinouchi, Kazuya, Ueda, Yasunori, Abe, Haruhiko, Sogabe, Taku, Ishida, Kenichiro, Mishima, Tsuyoshi, Ozaki, Tatsuhisa, Takayasu, Kohtaro, Iida, Yoshinori, Ohashi, Takuya, Toriyama, Chieko, Nakamura, Masayuki, Ueda, Yasuhiro, Sasaki, Shun, Matsumura, Mikiko, Iehara, Takashi, Date, Motoo, Ohnishi, Mitsuo, and Uematsu, Masaaki
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MYOCARDIAL infarction treatment , *GLOMERULAR filtration rate , *RESEARCH , *CALCIUM antagonists , *AGE distribution , *MULTIVARIATE analysis , *RESEARCH methodology , *MYOCARDIAL infarction , *RETROSPECTIVE studies , *CREATINE kinase , *MEDICAL care , *CORONARY disease , *EVALUATION research , *MEDICAL cooperation , *CORONARY angiography , *HOSPITAL mortality , *CARDIOVASCULAR system , *VENTRICULAR tachycardia , *COMPARATIVE studies , *DISEASE complications - Abstract
Background: Sudden cardiac arrest is a serious complication of acute myocardial infarction (MI). Although in-hospital mortality from MI has decreased, the mortality of MI patients complicated with out-of-hospital cardiac arrest (OHCA) remains high. However, the features of acute MI patients with OHCA have not been well known.Objectives: We sought to characterize the clinical and angiographic features of acute MI patients with OHCA comparing with those without OHCA.Methods: We retrospectively analyzed 480 consecutive patients with acute MI undergoing percutaneous coronary intervention. Patients complicated with OHCA were compared with patients without OHCA.Results: Of the patients, 141 (29%) were complicated with OHCA. Multivariate analysis revealed that age (odds ratio [OR]: 0.8; 95% confidence interval [CI]: 0.7 to 0.9 per 5 years; p < 0.001), estimated glomerular filtration rate (OR: 0.8; 95% CI: 0.7 to 0.8 per 10 ml/min/1.73 m2; p < 0.001), peak creatine kinase-myocardial band (OR: 1.3; 95% CI: 1.2 to 1.4 per 102 U/l; p < 0.001), calcium-channel antagonists use (OR: 0.4; 95% CI: 0.2 to 0.7; p = 0.002), the culprit lesion at the left main coronary artery (OR: 5.3; 95% CI: 1.9 to 15.1; p = 0.002), and the presence of chronic total occlusion (OR: 2.9; 95% CI: 1.5 to 5.7; p = 0.001) were significantly associated with OHCA.Conclusions: Younger age, no use of calcium-channel antagonists, worse renal function, larger infarct size, culprit lesion in the left main coronary artery, and having chronic total occlusion were associated with OHCA. [ABSTRACT FROM AUTHOR]- Published
- 2020
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