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Clinical and Angiographic Features of Patients With Out-of-Hospital Cardiac Arrest and Acute Myocardial Infarction.
- Source :
-
Journal of the American College of Cardiology (JACC) . Oct2020, Vol. 76 Issue 17, p1934-1943. 10p. - Publication Year :
- 2020
-
Abstract
- <bold>Background: </bold>Sudden cardiac arrest is a serious complication of acute myocardial infarction (MI). Although in-hospital mortality from MI has decreased, the mortality of MI patients complicated with out-of-hospital cardiac arrest (OHCA) remains high. However, the features of acute MI patients with OHCA have not been well known.<bold>Objectives: </bold>We sought to characterize the clinical and angiographic features of acute MI patients with OHCA comparing with those without OHCA.<bold>Methods: </bold>We retrospectively analyzed 480 consecutive patients with acute MI undergoing percutaneous coronary intervention. Patients complicated with OHCA were compared with patients without OHCA.<bold>Results: </bold>Of the patients, 141 (29%) were complicated with OHCA. Multivariate analysis revealed that age (odds ratio [OR]: 0.8; 95% confidence interval [CI]: 0.7 to 0.9 per 5 years; p < 0.001), estimated glomerular filtration rate (OR: 0.8; 95% CI: 0.7 to 0.8 per 10 ml/min/1.73 m2; p < 0.001), peak creatine kinase-myocardial band (OR: 1.3; 95% CI: 1.2 to 1.4 per 102 U/l; p < 0.001), calcium-channel antagonists use (OR: 0.4; 95% CI: 0.2 to 0.7; p = 0.002), the culprit lesion at the left main coronary artery (OR: 5.3; 95% CI: 1.9 to 15.1; p = 0.002), and the presence of chronic total occlusion (OR: 2.9; 95% CI: 1.5 to 5.7; p = 0.001) were significantly associated with OHCA.<bold>Conclusions: </bold>Younger age, no use of calcium-channel antagonists, worse renal function, larger infarct size, culprit lesion in the left main coronary artery, and having chronic total occlusion were associated with OHCA. [ABSTRACT FROM AUTHOR]
- Subjects :
- *MYOCARDIAL infarction treatment
*GLOMERULAR filtration rate
*RESEARCH
*CALCIUM antagonists
*AGE distribution
*MULTIVARIATE analysis
*RESEARCH methodology
*MYOCARDIAL infarction
*RETROSPECTIVE studies
*CREATINE kinase
*MEDICAL care
*CORONARY disease
*EVALUATION research
*MEDICAL cooperation
*CORONARY angiography
*HOSPITAL mortality
*CARDIOVASCULAR system
*VENTRICULAR tachycardia
*COMPARATIVE studies
*DISEASE complications
Subjects
Details
- Language :
- English
- ISSN :
- 07351097
- Volume :
- 76
- Issue :
- 17
- Database :
- Academic Search Index
- Journal :
- Journal of the American College of Cardiology (JACC)
- Publication Type :
- Academic Journal
- Accession number :
- 146573748
- Full Text :
- https://doi.org/10.1016/j.jacc.2020.08.057