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Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. - Provides the latest information on Hypothalamus - Offers outstanding and original reviews on a range of Hypothalamus research topics - Serves as an indispensable reference for researchers and students alike

A comprehensive resource for mental health professionals—now in a fully revised and updated tenth edition. The Handbook of Clinical Psychopharmacology for Therapists is the gold standard for mental health clinicians looking for clear, reliable information about the pharmacological treatment of mental health conditions. Organized by disorder and, within each disorder, by medication, this book is designed to familiarize clinicians and students with the basic terminology and models of psychopharmacology. This fully revised and updated tenth edition provides essential information on medications and treatment options, and includes the latest research on side effects, contraindications, and efficacy of all major medications prescribed for mental health disorders. This handbook makes it simple to: Get the facts about drug interactions and side effects Find out how medications affect adults, children, and adolescents differently Learn how different cultures view medical treatment—vital information for anyone treating clients from a variety of backgrounds Discontinue medication safely when needed The book also includes new material on novel and emerging medications, ethnopsychopharmacology, genomic testing, and psychopharmacology with older adults. This comprehensive guide to psychopharmacology has been adopted as a textbook at universities nationwide and is an important resource for every therapist's library.

The new edition of the highly popular, The Fractal Geometry of the Brain, reviews the most intriguing applications of fractal analysis in neuroscience with a focus on current and future potential, limits, advantages, and disadvantages. It brings an understanding of fractals to clinicians and researchers even if they do not have a mathematical background, and it serves as a valuable tool for teaching the translational applications of computational fractal-based models to both students and scholars. As a consequence of the novel research developed at Professor Di Ieva's laboratory and other centers around the world, the second edition will explore the use of computational fractal-based analysis in many clinical disciplines and different fields of research, including neurology and neurosurgery, neuroanatomy and psychology, magnetoencephalography (MEG), eye-tracking devices (for the fractal computational characterization of “scanpaths”),deep learning in image analysis, radiomics for the characterization of brain MRIs, characterization of neuropsychological and psychiatric diseases and traits, signal complexity analysis in time series, and functional MRI, amongst others.

Equine Neonatal Medicine A comprehensive guide to medical care for pregnant mares and neonatal foals Equine Neonatal Medicine offers an in-depth comprehensive reference for the clinical management of pregnant and periparturient mares and neonatal foals. Edited by leading experts in the field and written by experienced equine specialists, this textbook covers all aspects of providing veterinary care to mares and neonatal foals. Encompassing physiology, pathophysiology, theory, and practice, this textbook offers an authoritative, well-illustrated reference to equine perinatology. Topics covered include fetal monitoring, parturition, and peri-parturient disorders in the mare as well as diagnostic and therapeutic options for ill neonatal foals. The book: Covers aspects of veterinary care for the pregnant and peri-parturient mare and how to diagnose and treat the ill neonate Discusses fetal monitoring and parturition, and peri-parturient disorders in the mare Presents an exhaustive, detailed, and comprehensive reference for any veterinary practitioner involved with breeding management of horses and the care of neonatal foals Provides a clinical perspective, including both theory and practice Features more than 600 color images and diagrams to demonstrate the concepts discussed Equine Neonatal Medicine is an essential reference for any veterinary practitioner engaged with mares and foals, including specialists in equine medicine, equine and mixed animal practitioners, ambulatory practitioners, and veterinary students.

Each volume in the Autonomic Nervous System series deals with a different area of autonomic control in health and disease. This, the second volume, provides an overview on the nature of the factors that exert constraints on the differentiation and maturation of the autonomic nervous system. Subjects covered include: development of autonomic neurones; molecules affecting nerve growth and survival; regeneration after injury; and the degree to which the wiring of the nervous system is rigid or fixed.

This new volume provides a scientifically based exploration of the multifaceted world of endogenous opioids, including endorphins, enkephalins, dynorphins, endomorphins, and orphanin FQ/nociceptin, featuring a strong translational focus. Topics covered range from basic scientific investigations, to clinical applications, to investigations in areas such as oncology, childbirth, and disordered eating, to psychosocial contexts such as volunteering and positive emotions. One of the main goals of Endogenous Opioids is to provide recommendations for new directions in medical research and health policy that are rooted in sound scientific research.

Neuropathic Pain, Volume 179 of the latest release in the International Review of Neurobiology serial,, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in International Review on Neurobiology serials - Updated release includes the latest information on Neuropathic Pain

Executive Brain Vitality: Achieving Optimal Brain Health and Maintenance presents research on the effect of brain exercise as a preventative measure for neurodegenerative diseases and other conditions. This volume examines the neurological impact of such exercises from research to clinical application, offering up-to-date research and practical steps. The current book will be of interest to researchers in neurodegeneration and chronic disease as well as practitioners and clinicians interested in the preventative approach in medicine. - Discusses how to maintain and improve brain health - Includes how to mitigate chronic diseases - Provides practices for brain health and fitness - Suggests preventative exercises for neurodegenerative conditions

Written by established researchers, this two-volume publication provides timely, comprehensive and insightful reviews on recent discoveries in the etiology of hypertension. Structural changes of the blood vessels in hypertension in relation to connective tissue, cerebral vessel structure and innervation, smooth muscle cell hypertrophy and/or hyperplasia, and rarefaction of microvessels are discussed. Also presented are the effects of antihypertensive therapy on vessel structure and function. A unique feature is the inclusion of a chapter on pulmonary vascular changes in pulmonary hypertension, which shows certain changes that are similar to systemic hypertension. This book is of major interest to researchers involved in the study of hypertension and the biology of the blood vessels.

This book deals with molecular neurobiology based on neurochemical approaches and focuses on neural plasticity studied by neurophysiological methods. It offers discussions on prospects of neuroscience from the respective stances of the participants.

As drug discovery for neurodegenerative diseases is one of the largest subspecialties in the field of medicine, the book addresses topics that transcend the borders between disciplines, and presents a wealth of investigations into and discussions on critical questions relevant to the entire field of CNS drug research. This book provides medical professionals and researchers with a comprehensive overview of fundamental concepts and recent advances in neurochemistry, and offers new perspectives for all those involved with research in related disciplines. Combining both conventional and innovative approaches to the topic, the book offers a valuable guide for readers working in medicinal chemistry, the life sciences and allied fields. It summarizes the available data on the fundamentals of neurotransmitters, treatment of and advanced care for neurodegenerative diseases; and outlines current and future research directions in this field.

This is an open access title available under the terms of a CC BY-NC-ND 4.0 International licence. It is free to read at Oxford Academic and offered as a free PDF download from OUP and selected open access locations. Jasper's Basic Mechanisms of the Epilepsies has served as the definitive reference in the field of basic research in the epilepsies for five decades through four well-regarded editions. Since its inception, the book has been an indispensable must-read and belongs in the hands of every experimental epilepsy investigator, practicing epileptologist, clinical neuroscientist, and student for both clinical and basic science reference, doctoral and board exam preparation. This fifth edition is the most ambitious yet and remains the definitive reference in the field, providing encyclopedic and updated coverage of the current understanding of basic research in the epilepsies, while also mapping new research directions for the next decade, and reviewing how molecular laboratory evidence is now being translated into new therapeutics. In 79 chapters, the book considers the role of interactions between neurons, synapses, and glia in the initiation, spread, and arrest of seizures. It examines mechanisms of excitability, synchronization, seizure susceptibility and, ultimately, their contributions to epileptogenesis. It provides a framework for expanding the monogenic epilepsy genome and understanding the complex heredity responsible for common epilepsies. It explores the molecular and cellular disease mechanisms of ion channelopathies, developmental epilepsy genes, and progressive myoclonic epilepsies. It considers newly emerging mechanisms of epilepsy comorbidities. And, for the first time, it describes current efforts to identify biomarkers of disease progression and translate discoveries of epilepsy disease mechanisms into new therapeutic strategies at the frontier of molecular medicine.

This book discusses the regulation of gene transcription by neuronal activity that is evident in a large number of neuronal processes ranging from neural development and refinement of neuronal connections to learning and response to injury. Transcriptional Regulation by Neuronal Activity: To the Nucleus and Back, 2nd edition illustrates how signals are transmitted to the nucleus in response to neuronal activity, which genes are regulated and how this is achieved, and how these changes in gene expression alter neuronal function. The aim of this second edition is to highlight key advances in the field since the first edition. The book is divided into four sections. The first highlights how signals get to the nucleus from the membrane in response to synaptic or neuronal activity. Included are chapters on the pathways that transmit signals from synapses to nuclei. The second section focuses on epigenetic regulatory processes of activity-induced gene transcription, an area that has exploded in the past few years. The third section navigates the role of activity-induced genes in physiological processes such as learning and memory, and human developmental disorders such as those associated with the autism spectrum. The fourth section highlights groundbreaking technological advances in the field, which have allowed activity-regulated transcription to be used as a tool to study learning and memory.