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Brain tumors are an abnormal growth of cells in the brain. They can be classified into distinct grades based on their growth. Often grading is performed based on a histological image and is one of the most significant predictors of a patients prognosis, the higher the grade, the more aggressive the tumor. Correct diagnosis of a tumor grade remains challenging. Though histopathological grading has been shown to be prognostic, results are subject to interobserver variability, even among experienced pathologists. Recently, the World Health Organization reported that advances in molecular genetics have led to improvements in tumor classification. This paper seeks to integrate histological images and genetic data for improved computer-aided diagnosis. We propose a novel Multi-modal Outer Arithmetic Block (MOAB) based on arithmetic operations to combine latent representations of the different modalities for predicting the tumor grade (Grade \rom{2}, \rom{3} and \rom{4}). Extensive experiments evaluate the effectiveness of our approach. By applying MOAB to The Cancer Genome Atlas (TCGA) glioma dataset, we show that it can improve separation between similar classes (Grade \rom{2} and \rom{3}) and outperform prior state-of-the-art grade classification techniques.

This paper presents the Geometric Algebra approach to the Wigner little group for photons using the Spacetime Algebra, incorporating a mirror-based view for physical interpretation. The shift from a point-based view to a mirror-based view is a modern movement that allows for a more intuitive representation of geometric and physical entities, with vectors and their higher-grade counterparts viewed as hyperplanes. This reinterpretation simplifies the implementation of homogeneous representations of geometric objects within the Spacetime Algebra and enables a relative view via projective geometry. Then, after utilizing the intrinsic properties of Geometric Algebra, the Wigner little group is seen to induce a projective geometric algebra as a subalgebra of the Spacetime Algebra. However, the dimension-agnostic nature of Geometric Algebra enables the generalization of induced subalgebras to (1+n)-dimensional Minkowski geometric algebras, termed little photon algebras. The lightlike transformations (translations) in these little photon algebras are seen to leave invariant the (pseudo)canonical electromagetic field bivector. Geometrically, this corresponds to Lorentz transformations that do not change the intersection of the spacelike polarization hyperplane with the lightlike wavevector hyperplane while simultaneously not affecting the lightlike wavevector hyperplane. This provides for a framework that unifies the analysis of symmetries and substructures of point-based Geometric Algebra with mirror-based Geometric Algebra., Comment: 13 pages, 4 figures, to be published in Advances in Applied Clifford Algebras

We present GameNGen, the first game engine powered entirely by a neural model that enables real-time interaction with a complex environment over long trajectories at high quality. GameNGen can interactively simulate the classic game DOOM at over 20 frames per second on a single TPU. Next frame prediction achieves a PSNR of 29.4, comparable to lossy JPEG compression. Human raters are only slightly better than random chance at distinguishing short clips of the game from clips of the simulation. GameNGen is trained in two phases: (1) an RL-agent learns to play the game and the training sessions are recorded, and (2) a diffusion model is trained to produce the next frame, conditioned on the sequence of past frames and actions. Conditioning augmentations enable stable auto-regressive generation over long trajectories., Comment: Project page: https://gamengen.github.io/

Content creators often aim to create personalized images using personal subjects that go beyond the capabilities of conventional text-to-image models. Additionally, they may want the resulting image to encompass a specific location, style, ambiance, and more. Existing personalization methods may compromise personalization ability or the alignment to complex textual prompts. This trade-off can impede the fulfillment of user prompts and subject fidelity. We propose a new approach focusing on personalization methods for a \emph{single} prompt to address this issue. We term our approach prompt-aligned personalization. While this may seem restrictive, our method excels in improving text alignment, enabling the creation of images with complex and intricate prompts, which may pose a challenge for current techniques. In particular, our method keeps the personalized model aligned with a target prompt using an additional score distillation sampling term. We demonstrate the versatility of our method in multi- and single-shot settings and further show that it can compose multiple subjects or use inspiration from reference images, such as artworks. We compare our approach quantitatively and qualitatively with existing baselines and state-of-the-art techniques., Comment: Project page available at https://prompt-aligned.github.io/

State-of-the-art diffusion models can generate highly realistic images based on various conditioning like text, segmentation, and depth. However, an essential aspect often overlooked is the specific camera geometry used during image capture. The influence of different optical systems on the final scene appearance is frequently overlooked. This study introduces a framework that intimately integrates a text-to-image diffusion model with the particular lens geometry used in image rendering. Our method is based on a per-pixel coordinate conditioning method, enabling the control over the rendering geometry. Notably, we demonstrate the manipulation of curvature properties, achieving diverse visual effects, such as fish-eye, panoramic views, and spherical texturing using a single diffusion model., Comment: Project page at https://anylens-diffusion.github.io/

Recent advances in text-to-image generation models have unlocked vast potential for visual creativity. However, the users that use these models struggle with the generation of consistent characters, a crucial aspect for numerous real-world applications such as story visualization, game development, asset design, advertising, and more. Current methods typically rely on multiple pre-existing images of the target character or involve labor-intensive manual processes. In this work, we propose a fully automated solution for consistent character generation, with the sole input being a text prompt. We introduce an iterative procedure that, at each stage, identifies a coherent set of images sharing a similar identity and extracts a more consistent identity from this set. Our quantitative analysis demonstrates that our method strikes a better balance between prompt alignment and identity consistency compared to the baseline methods, and these findings are reinforced by a user study. To conclude, we showcase several practical applications of our approach., Comment: Accepted to SIGGRAPH 2024. Project page is available at https://omriavrahami.com/the-chosen-one/

Text-to-image (T2I) personalization allows users to guide the creative image generation process by combining their own visual concepts in natural language prompts. Recently, encoder-based techniques have emerged as a new effective approach for T2I personalization, reducing the need for multiple images and long training times. However, most existing encoders are limited to a single-class domain, which hinders their ability to handle diverse concepts. In this work, we propose a domain-agnostic method that does not require any specialized dataset or prior information about the personalized concepts. We introduce a novel contrastive-based regularization technique to maintain high fidelity to the target concept characteristics while keeping the predicted embeddings close to editable regions of the latent space, by pushing the predicted tokens toward their nearest existing CLIP tokens. Our experimental results demonstrate the effectiveness of our approach and show how the learned tokens are more semantic than tokens predicted by unregularized models. This leads to a better representation that achieves state-of-the-art performance while being more flexible than previous methods., Comment: Project page at https://datencoder.github.io

Text-to-image personalization aims to teach a pre-trained diffusion model to reason about novel, user provided concepts, embedding them into new scenes guided by natural language prompts. However, current personalization approaches struggle with lengthy training times, high storage requirements or loss of identity. To overcome these limitations, we propose an encoder-based domain-tuning approach. Our key insight is that by underfitting on a large set of concepts from a given domain, we can improve generalization and create a model that is more amenable to quickly adding novel concepts from the same domain. Specifically, we employ two components: First, an encoder that takes as an input a single image of a target concept from a given domain, e.g. a specific face, and learns to map it into a word-embedding representing the concept. Second, a set of regularized weight-offsets for the text-to-image model that learn how to effectively ingest additional concepts. Together, these components are used to guide the learning of unseen concepts, allowing us to personalize a model using only a single image and as few as 5 training steps - accelerating personalization from dozens of minutes to seconds, while preserving quality., Comment: Project page at https://tuning-encoder.github.io/

Synthesizing realistic animations of humans, animals, and even imaginary creatures, has long been a goal for artists and computer graphics professionals. Compared to the imaging domain, which is rich with large available datasets, the number of data instances for the motion domain is limited, particularly for the animation of animals and exotic creatures (e.g., dragons), which have unique skeletons and motion patterns. In this work, we present a Single Motion Diffusion Model, dubbed SinMDM, a model designed to learn the internal motifs of a single motion sequence with arbitrary topology and synthesize motions of arbitrary length that are faithful to them. We harness the power of diffusion models and present a denoising network explicitly designed for the task of learning from a single input motion. SinMDM is designed to be a lightweight architecture, which avoids overfitting by using a shallow network with local attention layers that narrow the receptive field and encourage motion diversity. SinMDM can be applied in various contexts, including spatial and temporal in-betweening, motion expansion, style transfer, and crowd animation. Our results show that SinMDM outperforms existing methods both in quality and time-space efficiency. Moreover, while current approaches require additional training for different applications, our work facilitates these applications at inference time. Our code and trained models are available at https://sinmdm.github.io/SinMDM-page., Comment: Video: https://www.youtube.com/watch?v=zuWpVTgb_0U, Project page: https://sinmdm.github.io/SinMDM-page, Code: https://github.com/SinMDM/SinMDM

Vision Transformers (ViT) serve as powerful vision models. Unlike convolutional neural networks, which dominated vision research in previous years, vision transformers enjoy the ability to capture long-range dependencies in the data. Nonetheless, an integral part of any transformer architecture, the self-attention mechanism, suffers from high latency and inefficient memory utilization, making it less suitable for high-resolution input images. To alleviate these shortcomings, hierarchical vision models locally employ self-attention on non-interleaving windows. This relaxation reduces the complexity to be linear in the input size; however, it limits the cross-window interaction, hurting the model performance. In this paper, we propose a new shift-invariant local attention layer, called query and attend (QnA), that aggregates the input locally in an overlapping manner, much like convolutions. The key idea behind QnA is to introduce learned queries, which allow fast and efficient implementation. We verify the effectiveness of our layer by incorporating it into a hierarchical vision transformer model. We show improvements in speed and memory complexity while achieving comparable accuracy with state-of-the-art models. Finally, our layer scales especially well with window size, requiring up-to x10 less memory while being up-to x5 faster than existing methods. The code is publicly available at \url{https://github.com/moabarar/qna}., Comment: CVPR 2022 - Oral

Image augmentation techniques apply transformation functions such as rotation, shearing, or color distortion on an input image. These augmentations were proven useful in improving neural networks' generalization ability. In this paper, we present a novel augmentation operation, InAugment, that exploits image internal statistics. The key idea is to copy patches from the image itself, apply augmentation operations on them, and paste them back at random positions on the same image. This method is simple and easy to implement and can be incorporated with existing augmentation techniques. We test InAugment on two popular datasets -- CIFAR and ImageNet. We show improvement over state-of-the-art augmentation techniques. Incorporating InAugment with Auto Augment yields a significant improvement over other augmentation techniques (e.g., +1% improvement over multiple architectures trained on the CIFAR dataset). We also demonstrate an increase for ResNet50 and EfficientNet-B3 top-1's accuracy on the ImageNet dataset compared to prior augmentation methods. Finally, our experiments suggest that training convolutional neural network using InAugment not only improves the model's accuracy and confidence but its performance on out-of-distribution images.

Statistical and computational methods are widely used in today's scientific studies. Using a female fertility potential in childhood cancer survivors as an example, we illustrate how these methods can be used to extract insight regarding biological processes from noisy observational data in order to inform decision making. We start by contextualizing the computational methods with the working example: the modelling of acute ovarian failure risk in female childhood cancer survivors to quantify the risk of permanent ovarian failure due to exposure to lifesaving but nonetheless toxic cancer treatments. This is followed by a description of the general framework of classification problems. We provide an overview of the modelling algorithms employed in our example, including one classic model (logistic regression) and two popular modern learning methods (random forest and support vector machines). Using the working example, we show the general steps of data preparation for modelling, variable selection steps for the classic model, and how model performance might be improved utilizing visualization tools. We end with a note on the importance of model evaluation., Comment: 15 pages, 9 figures and 1 table

We present a simple and intuitive Focus-and-eXpand (\fax) method to guide the training process of a neural network towards a specific solution. Optimizing a neural network is a highly non-convex problem. Typically, the space of solutions is large, with numerous possible local minima, where reaching a specific minimum depends on many factors. In many cases, however, a solution which considers specific aspects, or features, of the input is desired. For example, in the presence of bias, a solution that disregards the biased feature is a more robust and accurate one. Drawing inspiration from Parameter Continuation methods, we propose steering the training process to consider specific features in the input more than others, through gradual shifts in the input domain. \fax extracts a subset of features from each input data-point, and exposes the learner to these features first, Focusing the solution on them. Then, by using a blending/mixing parameter $\alpha$ it gradually eXpands the learning process to include all features of the input. This process encourages the consideration of the desired features more than others. Though not restricted to this field, we quantitatively evaluate the effectiveness of our approach on various Computer Vision tasks, and achieve state-of-the-art bias removal, improvements to an established augmentation method, and two examples of improvements to image classification tasks. Through these few examples we demonstrate the impact this approach potentially carries for a wide variety of problems, which stand to gain from understanding the solution landscape.

Many applications, such as autonomous driving, heavily rely on multi-modal data where spatial alignment between the modalities is required. Most multi-modal registration methods struggle computing the spatial correspondence between the images using prevalent cross-modality similarity measures. In this work, we bypass the difficulties of developing cross-modality similarity measures, by training an image-to-image translation network on the two input modalities. This learned translation allows training the registration network using simple and reliable mono-modality metrics. We perform multi-modal registration using two networks - a spatial transformation network and a translation network. We show that by encouraging our translation network to be geometry preserving, we manage to train an accurate spatial transformation network. Compared to state-of-the-art multi-modal methods our presented method is unsupervised, requiring no pairs of aligned modalities for training, and can be adapted to any pair of modalities. We evaluate our method quantitatively and qualitatively on commercial datasets, showing that it performs well on several modalities and achieves accurate alignment.

We report on the demonstration of the first axial AlInN ultraviolet core-shell nanowire light-emitting diodes with highly stable emission in the UV wavelength range. During the epitaxial growth of AlInN layer, an AlInN shell is spontaneously formed, resulted in the reduced nonradiative recombination on nanowire surface. The AlInN nanowires exhibit high internal quantum efficiency of ~ 52% at room temperature for emission at 295nm. The peak emission wavelength can be varied from 290 nm to 355 nm by changing the growth condition. Moreover, significantly strong transverse magnetic (TM) polarized emission is recorded which is ~ 4 times stronger compared to the transverse electric (TE) polarized light at 295 nm. This study provides alternative approach for the fabrication of new type of high-performance ultraviolet light-emitters.

Traditional image resizing methods usually work in pixel space and use various saliency measures. The challenge is to adjust the image shape while trying to preserve important content. In this paper we perform image resizing in feature space where the deep layers of a neural network contain rich important semantic information. We directly adjust the image feature maps, extracted from a pre-trained classification network, and reconstruct the resized image using a neural-network based optimization. This novel approach leverages the hierarchical encoding of the network, and in particular, the high-level discriminative power of its deeper layers, that recognizes semantic objects and regions and allows maintaining their aspect ratio. Our use of reconstruction from deep features diminishes the artifacts introduced by image-space resizing operators. We evaluate our method on benchmarks, compare to alternative approaches, and demonstrate its strength on challenging images., Comment: 13 pages, 21 figures

We present a simple randomized reduction from fully-dynamic integral matching algorithms to fully-dynamic "approximately-maximal" fractional matching algorithms. Applying this reduction to the recent fractional matching algorithm of Bhattacharya, Henzinger, and Nanongkai (SODA 2017), we obtain a novel result for the integral problem. Specifically, our main result is a randomized fully-dynamic $(2+\epsilon)$-approximate integral matching algorithm with small polylog worst-case update time. For the $(2+\epsilon)$-approximation regime only a \emph{fractional} fully-dynamic $(2+\epsilon)$-matching algorithm with worst-case polylog update time was previously known, due to Bhattacharya et al.~(SODA 2017). Our algorithm is the first algorithm that maintains approximate matchings with worst-case update time better than polynomial, for any constant approximation ratio. As a consequence, we also obtain the first constant-approximate worst-case polylogarithmic update time maximum weight matching algorithm.